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The map label for this gene is pbpG [H]

Identifier: 13472823

GI number: 13472823

Start: 2589370

End: 2591637

Strand: Reverse

Name: pbpG [H]

Synonym: mll3238

Alternate gene names: 13472823

Gene position: 2591637-2589370 (Counterclockwise)

Preceding gene: 13472824

Following gene: 13472822

Centisome position: 36.83

GC content: 65.74

Gene sequence:

>2268_bases
ATGGCGAACCGCAGAGACAGCCGCATCGAGCCCAGTTTCGAGGGACCGCCACAGGCGCGATCCCAGCCGGGTCTTTCGGT
GAGCGAAGAGGACCGCGTCGTGCCAAGCAACCGCAAAGCCTCCGCAAAACGCAAATCATCGAAGGCGAAATCGTCGCGCG
GCGGGCGCGGCAGGAGCCGGCGCGGCCTGTTCGGCGTGCTTGGCCGGCTTTTCTACTGGTGCTTCGTGCTCGCCATCTGG
GGTGGCATCGCGGTGGCCGGCGTCGTTATCTACTACGGCGCCAAGATGCCTGCGGCCACCACCTGGTCGATCCCCGACCG
CGCCCCCAACATCAAGATCGTCTCGGCCGATGACCAGTTGCTGGCAAACAGGGGCATGAGCGGCGGCGAAGCCGTCGGCC
TGCACGAAATGTCGCCTTACATTCCCGAAGCCGTCATCGCCATCGAGGACCGCCGGTTCTATTCGCATTTCGGCGTCGAC
CCGATCGGTCTGTCGCGCGCCATGGTGACCAACCTGCTCGGCGGGCATTTCTCGCAAGGCGGTTCGACGCTGACGCAGCA
ATTGGCCAAGAATCTGTTCCTGAAGCCTGACCGCACGCTGGAGCGCAAGGTACAGGAGGTGTTGCTGGCGCTGTGGCTGG
AGCACAAGCACACCAAGGACCAGATCCTCGAAATGTACCTCAACCGGGTCTATTTCGGCTCCGGCGCCTTTGGTGTCGAG
GCGGCTTCGCGGCGTTATTTCGGCAAGAGCGCGCGCGATGTCACGCTCTCGGAAGCAGCGCTGCTTGCGGGCTTGCTGAA
GGCGCCGTCGCGGCTGTCGCCGGCGCGCGATCCCAAGGCCGCGGAGGAGCGTTCGCAGCTTGTGCTCGCGGCTATGCGTG
AAGAGGGCAAGATCAGTGACAAGGAGTTGAAGACGGCGCTCAGCGCGCCGGCGACGCGCGCGCCGTCCTACTGGACCGGT
TCGGAGAACTATGTCGCCGACACCATCATGGAAGAACTGCCAGACCTGATCGGCGACGTGCGCGGCGACATCGTCATCGA
TTCCACCGTCGACCTGAACCTGCAGAAGCTCGCCGAGCAGTCGATCCGCCGGCTGATCGACGAAAGCGGCAAGAAGCTCA
ACGTCACCCAGGGCGCGCTGGTGTCGATCGACGATTCCGGCGCGGTGCGCGCTATGGTCGGCGGCTACGACTATTCGACC
AGCCAGTTCGACCGCGCCTCGGAAGCGCGCCGCCAGCCGGGCTCGGCGTTCAAGCCGTTCGTCTATATGGCGGCACTGGA
AGCCGGCCGCACGCCCGACAGCATCCGCAACGACGCGCCGATCAAGATCGGCAACTGGACGCCCGACAATTACGGCGGCA
AATATTTTGGCAAGGTCACGCTGGCGACGGCGCTGGCCAAGTCGCTGAACTCGGTCGCCGCGCAGCTGACGATGGAGGTC
GGGCCGAACGCGGTGGTGGAAGCGGCGCACCGCATGGGCATCCAGTCCGAACTGCAGGCCAACACCTCGATCGCGCTCGG
CACCTCGGAAGTGACGCCGCTGGAGCTGACGTCGGCCTATGTGCCGTTCGCCAATGGCGGCTACAAGCCCGACATCCACT
TCATCCGCCGCATCACGACCGCCGAGGGCAAGGTGCTCTACGACAGCGGTGGTGGCAGCGCGCCGCGTGTCGTGAAACCC
GAGATCGTCGGCATGATGAACTCGATGATGACCGGCACCGTCGAGGTCGGCACGGCCAAGAAGGCGGCCTTCGCCTGGCC
GTCGGCCGGCAAGACCGGCACCAGCCAGAATTCGCGCGATGCCTGGTTCGTCGGCTACACCGCCAATCTCACCACCGGTG
TGTGGTTCGGCAATGATGACGGCACGGGGATGAAGAAGGTCACCGGTGGCGCGCTGCCGGCGCAGGCCTGGCACGAATTC
ATGGTCGCCGCACACGAGGGCGTGCCGGTGCGGCCGCTGCCCGGCACCTGGAAATCGACGCCGGCCGACACGATCGTGCC
CGACGACATACCTTCGGCCGACAACAACCAGCCAGCGCCGGTCCCGTCCGCGTCGGTTGGCCAGAAGGCGCCGTCAACAC
AGCCGACCCAGGCGGCAGCGCCGGCCCGTGTGGCGCGGCCTGCCCAGACCGTCGATGCCGATGGCTTCAACATGCCAGCG
GATGACGGCACCACTGCTTCGGTCGGCCATCCGGTGCCGCCGGGCAATGTTGGCGGTCCGCTGAAGAAGAAACAGACCTC
GATCCTGGATATTCTGGGCGGCGGCTGA

Upstream 100 bases:

>100_bases
TACTAATCGCCTCGAATTTTTCCGATTTAACCCGCCCTTAAATCGCCGCATCTACTCTGCAACCGGAGCGCCATAGGCAC
CGGGGACAGCAAGCGCAGGC

Downstream 100 bases:

>100_bases
AGGCTGTCGCCCCGGCGGTTCGCAGCGGCGTCAATCCGCCTCTCGCCAGCGCCACGCTGTTCGGCTACACCTCCGGCCGG
AGACCGCGACATGGCTGAAT

Product: penicillin-binding protein

Products: NA

Alternate protein names: PBP-2D; PBP2d [H]

Number of amino acids: Translated: 755; Mature: 754

Protein sequence:

>755_residues
MANRRDSRIEPSFEGPPQARSQPGLSVSEEDRVVPSNRKASAKRKSSKAKSSRGGRGRSRRGLFGVLGRLFYWCFVLAIW
GGIAVAGVVIYYGAKMPAATTWSIPDRAPNIKIVSADDQLLANRGMSGGEAVGLHEMSPYIPEAVIAIEDRRFYSHFGVD
PIGLSRAMVTNLLGGHFSQGGSTLTQQLAKNLFLKPDRTLERKVQEVLLALWLEHKHTKDQILEMYLNRVYFGSGAFGVE
AASRRYFGKSARDVTLSEAALLAGLLKAPSRLSPARDPKAAEERSQLVLAAMREEGKISDKELKTALSAPATRAPSYWTG
SENYVADTIMEELPDLIGDVRGDIVIDSTVDLNLQKLAEQSIRRLIDESGKKLNVTQGALVSIDDSGAVRAMVGGYDYST
SQFDRASEARRQPGSAFKPFVYMAALEAGRTPDSIRNDAPIKIGNWTPDNYGGKYFGKVTLATALAKSLNSVAAQLTMEV
GPNAVVEAAHRMGIQSELQANTSIALGTSEVTPLELTSAYVPFANGGYKPDIHFIRRITTAEGKVLYDSGGGSAPRVVKP
EIVGMMNSMMTGTVEVGTAKKAAFAWPSAGKTGTSQNSRDAWFVGYTANLTTGVWFGNDDGTGMKKVTGGALPAQAWHEF
MVAAHEGVPVRPLPGTWKSTPADTIVPDDIPSADNNQPAPVPSASVGQKAPSTQPTQAAAPARVARPAQTVDADGFNMPA
DDGTTASVGHPVPPGNVGGPLKKKQTSILDILGGG

Sequences:

>Translated_755_residues
MANRRDSRIEPSFEGPPQARSQPGLSVSEEDRVVPSNRKASAKRKSSKAKSSRGGRGRSRRGLFGVLGRLFYWCFVLAIW
GGIAVAGVVIYYGAKMPAATTWSIPDRAPNIKIVSADDQLLANRGMSGGEAVGLHEMSPYIPEAVIAIEDRRFYSHFGVD
PIGLSRAMVTNLLGGHFSQGGSTLTQQLAKNLFLKPDRTLERKVQEVLLALWLEHKHTKDQILEMYLNRVYFGSGAFGVE
AASRRYFGKSARDVTLSEAALLAGLLKAPSRLSPARDPKAAEERSQLVLAAMREEGKISDKELKTALSAPATRAPSYWTG
SENYVADTIMEELPDLIGDVRGDIVIDSTVDLNLQKLAEQSIRRLIDESGKKLNVTQGALVSIDDSGAVRAMVGGYDYST
SQFDRASEARRQPGSAFKPFVYMAALEAGRTPDSIRNDAPIKIGNWTPDNYGGKYFGKVTLATALAKSLNSVAAQLTMEV
GPNAVVEAAHRMGIQSELQANTSIALGTSEVTPLELTSAYVPFANGGYKPDIHFIRRITTAEGKVLYDSGGGSAPRVVKP
EIVGMMNSMMTGTVEVGTAKKAAFAWPSAGKTGTSQNSRDAWFVGYTANLTTGVWFGNDDGTGMKKVTGGALPAQAWHEF
MVAAHEGVPVRPLPGTWKSTPADTIVPDDIPSADNNQPAPVPSASVGQKAPSTQPTQAAAPARVARPAQTVDADGFNMPA
DDGTTASVGHPVPPGNVGGPLKKKQTSILDILGGG
>Mature_754_residues
ANRRDSRIEPSFEGPPQARSQPGLSVSEEDRVVPSNRKASAKRKSSKAKSSRGGRGRSRRGLFGVLGRLFYWCFVLAIWG
GIAVAGVVIYYGAKMPAATTWSIPDRAPNIKIVSADDQLLANRGMSGGEAVGLHEMSPYIPEAVIAIEDRRFYSHFGVDP
IGLSRAMVTNLLGGHFSQGGSTLTQQLAKNLFLKPDRTLERKVQEVLLALWLEHKHTKDQILEMYLNRVYFGSGAFGVEA
ASRRYFGKSARDVTLSEAALLAGLLKAPSRLSPARDPKAAEERSQLVLAAMREEGKISDKELKTALSAPATRAPSYWTGS
ENYVADTIMEELPDLIGDVRGDIVIDSTVDLNLQKLAEQSIRRLIDESGKKLNVTQGALVSIDDSGAVRAMVGGYDYSTS
QFDRASEARRQPGSAFKPFVYMAALEAGRTPDSIRNDAPIKIGNWTPDNYGGKYFGKVTLATALAKSLNSVAAQLTMEVG
PNAVVEAAHRMGIQSELQANTSIALGTSEVTPLELTSAYVPFANGGYKPDIHFIRRITTAEGKVLYDSGGGSAPRVVKPE
IVGMMNSMMTGTVEVGTAKKAAFAWPSAGKTGTSQNSRDAWFVGYTANLTTGVWFGNDDGTGMKKVTGGALPAQAWHEFM
VAAHEGVPVRPLPGTWKSTPADTIVPDDIPSADNNQPAPVPSASVGQKAPSTQPTQAAAPARVARPAQTVDADGFNMPAD
DGTTASVGHPVPPGNVGGPLKKKQTSILDILGGG

Specific function: Involved in the polymerization and cross-linking of spore peptidoglycan. May be required for synthesis of the spore germ cell wall, the first layer of peptidoglycan synthesized on the surface of the inner forespore membrane [H]

COG id: COG0744

COG function: function code M; Membrane carboxypeptidase (penicillin-binding protein)

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the transpeptidase family [H]

Homologues:

Organism=Escherichia coli, GI1786343, Length=538, Percent_Identity=33.271375464684, Blast_Score=236, Evalue=5e-63,
Organism=Escherichia coli, GI1788867, Length=524, Percent_Identity=32.6335877862595, Blast_Score=204, Evalue=2e-53,
Organism=Escherichia coli, GI87082258, Length=295, Percent_Identity=38.3050847457627, Blast_Score=194, Evalue=2e-50,
Organism=Escherichia coli, GI1789601, Length=242, Percent_Identity=36.7768595041322, Blast_Score=114, Evalue=2e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001264
- InterPro:   IPR011816
- InterPro:   IPR001460 [H]

Pfam domain/function: PF00912 Transgly; PF00905 Transpeptidase [H]

EC number: 2.4.1.129; 3.4.-.- [C]

Molecular weight: Translated: 80525; Mature: 80394

Theoretical pI: Translated: 9.62; Mature: 9.62

Prosite motif: PS01159 WW_DOMAIN_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANRRDSRIEPSFEGPPQARSQPGLSVSEEDRVVPSNRKASAKRKSSKAKSSRGGRGRSR
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCC
RGLFGVLGRLFYWCFVLAIWGGIAVAGVVIYYGAKMPAATTWSIPDRAPNIKIVSADDQL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCCCCCEEEECCCHHH
LANRGMSGGEAVGLHEMSPYIPEAVIAIEDRRFYSHFGVDPIGLSRAMVTNLLGGHFSQG
HHHCCCCCCCEECCHHCCCCCCCEEEEEECCHHHHHCCCCCHHHHHHHHHHHHCCCCCCC
GSTLTQQLAKNLFLKPDRTLERKVQEVLLALWLEHKHTKDQILEMYLNRVYFGSGAFGVE
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHEECCCCCCHH
AASRRYFGKSARDVTLSEAALLAGLLKAPSRLSPARDPKAAEERSQLVLAAMREEGKISD
HHHHHHCCCCCCCCHHHHHHHHHHHHHCCHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCH
KELKTALSAPATRAPSYWTGSENYVADTIMEELPDLIGDVRGDIVIDSTVDLNLQKLAEQ
HHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHH
SIRRLIDESGKKLNVTQGALVSIDDSGAVRAMVGGYDYSTSQFDRASEARRQPGSAFKPF
HHHHHHHHCCCEEEECCCEEEEECCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCCCHH
VYMAALEAGRTPDSIRNDAPIKIGNWTPDNYGGKYFGKVTLATALAKSLNSVAAQLTMEV
HHHHHHHCCCCCHHHCCCCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHC
GPNAVVEAAHRMGIQSELQANTSIALGTSEVTPLELTSAYVPFANGGYKPDIHFIRRITT
CCHHHHHHHHHCCCHHHHHCCCEEEECCCCCCCEEHHHCCCCCCCCCCCCCHHHHHHHHC
AEGKVLYDSGGGSAPRVVKPEIVGMMNSMMTGTVEVGTAKKAAFAWPSAGKTGTSQNSRD
CCCEEEEECCCCCCCCEECHHHHHHHHHHHCCEEEECCCCHHEEECCCCCCCCCCCCCCC
AWFVGYTANLTTGVWFGNDDGTGMKKVTGGALPAQAWHEFMVAAHEGVPVRPLPGTWKST
EEEEEEECCCEEEEEECCCCCCCHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCC
PADTIVPDDIPSADNNQPAPVPSASVGQKAPSTQPTQAAAPARVARPAQTVDADGFNMPA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCCHHHCCCCHHCCCCCCCCCC
DDGTTASVGHPVPPGNVGGPLKKKQTSILDILGGG
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCC
>Mature Secondary Structure 
ANRRDSRIEPSFEGPPQARSQPGLSVSEEDRVVPSNRKASAKRKSSKAKSSRGGRGRSR
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCC
RGLFGVLGRLFYWCFVLAIWGGIAVAGVVIYYGAKMPAATTWSIPDRAPNIKIVSADDQL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCCCCCEEEECCCHHH
LANRGMSGGEAVGLHEMSPYIPEAVIAIEDRRFYSHFGVDPIGLSRAMVTNLLGGHFSQG
HHHCCCCCCCEECCHHCCCCCCCEEEEEECCHHHHHCCCCCHHHHHHHHHHHHCCCCCCC
GSTLTQQLAKNLFLKPDRTLERKVQEVLLALWLEHKHTKDQILEMYLNRVYFGSGAFGVE
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHEECCCCCCHH
AASRRYFGKSARDVTLSEAALLAGLLKAPSRLSPARDPKAAEERSQLVLAAMREEGKISD
HHHHHHCCCCCCCCHHHHHHHHHHHHHCCHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCH
KELKTALSAPATRAPSYWTGSENYVADTIMEELPDLIGDVRGDIVIDSTVDLNLQKLAEQ
HHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHH
SIRRLIDESGKKLNVTQGALVSIDDSGAVRAMVGGYDYSTSQFDRASEARRQPGSAFKPF
HHHHHHHHCCCEEEECCCEEEEECCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCCCHH
VYMAALEAGRTPDSIRNDAPIKIGNWTPDNYGGKYFGKVTLATALAKSLNSVAAQLTMEV
HHHHHHHCCCCCHHHCCCCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHC
GPNAVVEAAHRMGIQSELQANTSIALGTSEVTPLELTSAYVPFANGGYKPDIHFIRRITT
CCHHHHHHHHHCCCHHHHHCCCEEEECCCCCCCEEHHHCCCCCCCCCCCCCHHHHHHHHC
AEGKVLYDSGGGSAPRVVKPEIVGMMNSMMTGTVEVGTAKKAAFAWPSAGKTGTSQNSRD
CCCEEEEECCCCCCCCEECHHHHHHHHHHHCCEEEECCCCHHEEECCCCCCCCCCCCCCC
AWFVGYTANLTTGVWFGNDDGTGMKKVTGGALPAQAWHEFMVAAHEGVPVRPLPGTWKST
EEEEEEECCCEEEEEECCCCCCCHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCC
PADTIVPDDIPSADNNQPAPVPSASVGQKAPSTQPTQAAAPARVARPAQTVDADGFNMPA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCCHHHCCCCHHCCCCCCCCCC
DDGTTASVGHPVPPGNVGGPLKKKQTSILDILGGG
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferases; Acyltransferases; Aminoacyltransferases [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]