Click here to switch to the map view.

The map label for this gene is des [H]

Identifier: 13472810

GI number: 13472810

Start: 2575302

End: 2576324

Strand: Direct

Name: des [H]

Synonym: mlr3223

Alternate gene names: 13472810

Gene position: 2575302-2576324 (Clockwise)

Preceding gene: 13472809

Following gene: 13472818

Centisome position: 36.6

GC content: 64.13

Gene sequence:

>1023_bases
ATGAACATGATTTCCCCCGATGCGGCCGCCAACAGCAAGCGTGCCTGGCTGAAGATCCTCGCGCGCTACAAGAAGCCGGA
CCGGCGACGCAGCGCCGTCGAACTTGCCATCACCCTCATCCCGTTCGCCACGCTCTGGGCGCTGTCCTCGGCCGCCTATG
CCTATGGCCATTGGTGGGGGCTGATCCTGATCCTTCCGGCGGCCGGGTTCTTGGTGCGCATCTTCATGATCCAGCACGAT
TGCGGCCATGGCTCCTTCTTCGCCAACCGCTATGCCGACGACTGGATCGGCCGCGCGCTCGGCGTCCTGACTTTGACGCC
CTACGATTGCTGGCGGCGCGCCCACGCGACGCATCATGCCAGCGCCGGCAATCTTGACGAGCGCGGCATGGGCGATATCA
GGACGCTGACCGTTGCCGAATACCGGCAATTGTCCTGGCGCGGGCGCCTCGCCTACCGCCTCTATCGCCATCCGCTGGTG
ATGTTCGGGCTTGGACCGATCTGGCTGTTCATCTTCTCGCAAAGGCTGCCCATCGGCATGATGCGCGGCGGCCTGACGCC
CTGGGTGTCGTCCATGACCACCAATCTCGCCATCGCGCTGGCTGCGGCCCTGCTTATCTGGGCCGTCGGCCCCGGTGCTT
TCCTGGTCGTCCATCTGCCGATCGTCATCCTTGCCGGCTCGGCCGGAATCTGGCTGTTCTATGTCCAGCACCAGTTCGAG
GAGACGGAATGGGCTAAGGATGACGACTGGGAGTTTCAGCATGCCGCCTTGCACGGCTCGTCCTATTACGACCTGCCGCC
GGTGCTGAACTGGTTCACCGGCAATATCGGCGTCCATCACGTCCACCATCTCTCCGCCAAGGTGCCGGGCTACCGGCTGC
AGGAAGTGCTGCGCGATTATCCGGAACTGCGCGGCATCGGTCGCGTCACGCTGCTCGACAGCCTGCGCTGCGTCAAACTG
GCACTATGGGACGAGAACCGCCGCAAGCTGGTGTCGTTCCGCGAGGCACGGGCGACGATGTAG

Upstream 100 bases:

>100_bases
GGCGGCAGTAGCTCTCGGCACTCTTTACGCGACAATTACGCACAGTAATTTTGCGTGATGGCTGCCTTGCGGTAGCCACA
CGCCGCGCCTATGCTTCCTG

Downstream 100 bases:

>100_bases
AGCAATTCCAGGAAAAGTGTGAGCGGTTTTCCCGGGAAAAGCGCGTAGCGCTTTCCCTTGGGAATTGCGTCAAAACATAG
AGTTGGAGCGGTTCGCCGTT

Product: fatty acid desaturase

Products: NA

Alternate protein names: Delta(5) acyl-lipid desaturase; Delta(5) desaturase [H]

Number of amino acids: Translated: 340; Mature: 340

Protein sequence:

>340_residues
MNMISPDAAANSKRAWLKILARYKKPDRRRSAVELAITLIPFATLWALSSAAYAYGHWWGLILILPAAGFLVRIFMIQHD
CGHGSFFANRYADDWIGRALGVLTLTPYDCWRRAHATHHASAGNLDERGMGDIRTLTVAEYRQLSWRGRLAYRLYRHPLV
MFGLGPIWLFIFSQRLPIGMMRGGLTPWVSSMTTNLAIALAAALLIWAVGPGAFLVVHLPIVILAGSAGIWLFYVQHQFE
ETEWAKDDDWEFQHAALHGSSYYDLPPVLNWFTGNIGVHHVHHLSAKVPGYRLQEVLRDYPELRGIGRVTLLDSLRCVKL
ALWDENRRKLVSFREARATM

Sequences:

>Translated_340_residues
MNMISPDAAANSKRAWLKILARYKKPDRRRSAVELAITLIPFATLWALSSAAYAYGHWWGLILILPAAGFLVRIFMIQHD
CGHGSFFANRYADDWIGRALGVLTLTPYDCWRRAHATHHASAGNLDERGMGDIRTLTVAEYRQLSWRGRLAYRLYRHPLV
MFGLGPIWLFIFSQRLPIGMMRGGLTPWVSSMTTNLAIALAAALLIWAVGPGAFLVVHLPIVILAGSAGIWLFYVQHQFE
ETEWAKDDDWEFQHAALHGSSYYDLPPVLNWFTGNIGVHHVHHLSAKVPGYRLQEVLRDYPELRGIGRVTLLDSLRCVKL
ALWDENRRKLVSFREARATM
>Mature_340_residues
MNMISPDAAANSKRAWLKILARYKKPDRRRSAVELAITLIPFATLWALSSAAYAYGHWWGLILILPAAGFLVRIFMIQHD
CGHGSFFANRYADDWIGRALGVLTLTPYDCWRRAHATHHASAGNLDERGMGDIRTLTVAEYRQLSWRGRLAYRLYRHPLV
MFGLGPIWLFIFSQRLPIGMMRGGLTPWVSSMTTNLAIALAAALLIWAVGPGAFLVVHLPIVILAGSAGIWLFYVQHQFE
ETEWAKDDDWEFQHAALHGSSYYDLPPVLNWFTGNIGVHHVHHLSAKVPGYRLQEVLRDYPELRGIGRVTLLDSLRCVKL
ALWDENRRKLVSFREARATM

Specific function: Catalyzes the introduction of a cis-double bond at the delta(5) position of existing saturated fatty acids attached to membrane phospholipids. It is not strictly specific for palmitic acid (C16) but can also accept C14 as well as C18 species to yield unsa

COG id: COG3239

COG function: function code I; Fatty acid desaturase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fatty acid desaturase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005804 [H]

Pfam domain/function: PF00487 FA_desaturase [H]

EC number: 1.14.99.-

Molecular weight: Translated: 38629; Mature: 38629

Theoretical pI: Translated: 9.92; Mature: 9.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNMISPDAAANSKRAWLKILARYKKPDRRRSAVELAITLIPFATLWALSSAAYAYGHWWG
CCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LILILPAAGFLVRIFMIQHDCGHGSFFANRYADDWIGRALGVLTLTPYDCWRRAHATHHA
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHEEECHHHHHHHHHHHCCC
SAGNLDERGMGDIRTLTVAEYRQLSWRGRLAYRLYRHPLVMFGLGPIWLFIFSQRLPIGM
CCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHCCHHEECHHHHHHHHHHCCCCHHH
MRGGLTPWVSSMTTNLAIALAAALLIWAVGPGAFLVVHLPIVILAGSAGIWLFYVQHQFE
HHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHEECCCCEEEEEEEHHHH
ETEWAKDDDWEFQHAALHGSSYYDLPPVLNWFTGNIGVHHVHHLSAKVPGYRLQEVLRDY
HCCCCCCCCCCHHHHEECCCCCCCCCHHHHHHCCCCCHHHHHHHHCCCCCHHHHHHHHHH
PELRGIGRVTLLDSLRCVKLALWDENRRKLVSFREARATM
HHHCCCCHHHHHHHHHHEEEEEECCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MNMISPDAAANSKRAWLKILARYKKPDRRRSAVELAITLIPFATLWALSSAAYAYGHWWG
CCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LILILPAAGFLVRIFMIQHDCGHGSFFANRYADDWIGRALGVLTLTPYDCWRRAHATHHA
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHEEECHHHHHHHHHHHCCC
SAGNLDERGMGDIRTLTVAEYRQLSWRGRLAYRLYRHPLVMFGLGPIWLFIFSQRLPIGM
CCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHCCHHEECHHHHHHHHHHCCCCHHH
MRGGLTPWVSSMTTNLAIALAAALLIWAVGPGAFLVVHLPIVILAGSAGIWLFYVQHQFE
HHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHEECCCCEEEEEEEHHHH
ETEWAKDDDWEFQHAALHGSSYYDLPPVLNWFTGNIGVHHVHHLSAKVPGYRLQEVLRDY
HCCCCCCCCCCHHHHEECCCCCCCCCHHHHHHCCCCCHHHHHHHHCCCCCHHHHHHHHHH
PELRGIGRVTLLDSLRCVKLALWDENRRKLVSFREARATM
HHHCCCCHHHHHHHHHHEEEEEECCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9555904; 9384377 [H]