Click here to switch to the map view.

The map label for this gene is sppA [C]

Identifier: 13472792

GI number: 13472792

Start: 2561470

End: 2562426

Strand: Direct

Name: sppA [C]

Synonym: mlr3201

Alternate gene names: 13472792

Gene position: 2561470-2562426 (Clockwise)

Preceding gene: 13472785

Following gene: 13472793

Centisome position: 36.4

GC content: 62.38

Gene sequence:

>957_bases
ATGGCATTGAGAGCCGACGACCTGATCGACCGCCGCCGTTTGCGGCGCAAGCTGACATTCTGGCGTGTTGCGGCCATCGG
CATCGTCGCCCTCGGAGTGATCGCGCTGTCGGCCTGGTTCTATCGCGACGATCTCGGCGGCTCGACTGTCGACCATATCG
CCAAGGTCAGGATCGAAGGTACGATCACCGAGGACGAGGAACTGATCAAGCGTCTGGAAGACATCCGCAAGTCGTCGAAG
GTGAAGGGCGTGATCCTCGCGATCGATTCCCCCGGCGGCACCACCGTCGGCGGTGAATCGATCTATGAGGAAGTGCGCAA
GGTGGCTGCCGACAAGCCGGTCGTGGCCGAAGTCGGCACGCTCGCCGCATCGGCGGGCTATATGATCGCAAGTGCTGCCG
ACCACATTGTCGCCCGCAAAACCTCGATCGTCGGTTCGATCGGCGTGCTGATCCAGTATCCTGACGTCAGCGGCCTGATG
GACAAGCTCGGCATCAAGCTGGAGGAGGTGAAATCCTCGCCGCTCAAGGCTTCACCTTCTCCCTTCAAGCCGACCAATGA
CGACGAGCGCGCCATGGTCCGCAAGCTCATCCTCGACAGCTACGACTGGTTTGTCGGCATCGTCGCCGAACGCCGCAAGA
TGACCCACGAACAGGCGCTGGCGCTTGCCGACGGATCGATCTTCACCGGCCGCCAGGGTGTCACCAACGGGCTGATCGAT
GCCGTCGGCGGCGAAACCGAGGCGATCGACTGGCTGGCGACCAAGGGCGTCGACGCCAAGCTCAAGGTGGTCGAATGGAA
GGACACGGAGCGCCGCGGCAGCTTCCTGTGGTCAAAAGCCATGGTGAAAACGGTCGGCAGCGCGCTCGGCCTGCCGGGCT
ACAGCAGTGATGTCATCCACGAACTTGGCGCCGACCGCTTGTTTCTTGACGGCCTCGTTTCTGTCTGGCACCCTTGA

Upstream 100 bases:

>100_bases
GACGCGGGCGGATTGCCGCGCCATAGGCAAGACGAACTGCTTCCCGATGAAGACATCATGGTCTAAAAGCGTCTCTTCCC
GCCGACTGTGAGGCTGAACC

Downstream 100 bases:

>100_bases
GCGCCGTTTGGAACAGCTGAAAAAGCCAATAAAATCATCCTCATAATTTCGACCGAACTGCTTTCACGGGGACCCGTCTG
ATGATCAAGTCCGAACTTGT

Product: protease IV

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 318; Mature: 317

Protein sequence:

>318_residues
MALRADDLIDRRRLRRKLTFWRVAAIGIVALGVIALSAWFYRDDLGGSTVDHIAKVRIEGTITEDEELIKRLEDIRKSSK
VKGVILAIDSPGGTTVGGESIYEEVRKVAADKPVVAEVGTLAASAGYMIASAADHIVARKTSIVGSIGVLIQYPDVSGLM
DKLGIKLEEVKSSPLKASPSPFKPTNDDERAMVRKLILDSYDWFVGIVAERRKMTHEQALALADGSIFTGRQGVTNGLID
AVGGETEAIDWLATKGVDAKLKVVEWKDTERRGSFLWSKAMVKTVGSALGLPGYSSDVIHELGADRLFLDGLVSVWHP

Sequences:

>Translated_318_residues
MALRADDLIDRRRLRRKLTFWRVAAIGIVALGVIALSAWFYRDDLGGSTVDHIAKVRIEGTITEDEELIKRLEDIRKSSK
VKGVILAIDSPGGTTVGGESIYEEVRKVAADKPVVAEVGTLAASAGYMIASAADHIVARKTSIVGSIGVLIQYPDVSGLM
DKLGIKLEEVKSSPLKASPSPFKPTNDDERAMVRKLILDSYDWFVGIVAERRKMTHEQALALADGSIFTGRQGVTNGLID
AVGGETEAIDWLATKGVDAKLKVVEWKDTERRGSFLWSKAMVKTVGSALGLPGYSSDVIHELGADRLFLDGLVSVWHP
>Mature_317_residues
ALRADDLIDRRRLRRKLTFWRVAAIGIVALGVIALSAWFYRDDLGGSTVDHIAKVRIEGTITEDEELIKRLEDIRKSSKV
KGVILAIDSPGGTTVGGESIYEEVRKVAADKPVVAEVGTLAASAGYMIASAADHIVARKTSIVGSIGVLIQYPDVSGLMD
KLGIKLEEVKSSPLKASPSPFKPTNDDERAMVRKLILDSYDWFVGIVAERRKMTHEQALALADGSIFTGRQGVTNGLIDA
VGGETEAIDWLATKGVDAKLKVVEWKDTERRGSFLWSKAMVKTVGSALGLPGYSSDVIHELGADRLFLDGLVSVWHP

Specific function: Digestion Of The Cleaved Signal Peptides. This Activity Is Necessary To Maintain Proper Secretion Of Mature Proteins Across The Membrane. [C]

COG id: COG0616

COG function: function code OU; Periplasmic serine proteases (ClpP class)

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S49 family [H]

Homologues:

Organism=Escherichia coli, GI1788064, Length=225, Percent_Identity=32.4444444444444, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1787527, Length=168, Percent_Identity=30.3571428571429, Blast_Score=70, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004635
- InterPro:   IPR002142 [H]

Pfam domain/function: PF01343 Peptidase_S49 [H]

EC number: 3.4.21.-

Molecular weight: Translated: 34511; Mature: 34380

Theoretical pI: Translated: 7.10; Mature: 7.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALRADDLIDRRRLRRKLTFWRVAAIGIVALGVIALSAWFYRDDLGGSTVDHIAKVRIEG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHEEEEC
TITEDEELIKRLEDIRKSSKVKGVILAIDSPGGTTVGGESIYEEVRKVAADKPVVAEVGT
CCCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCHHHHHHH
LAASAGYMIASAADHIVARKTSIVGSIGVLIQYPDVSGLMDKLGIKLEEVKSSPLKASPS
HHHHCCHHHHHHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHCCCHHHHCCCCCCCCCC
PFKPTNDDERAMVRKLILDSYDWFVGIVAERRKMTHEQALALADGSIFTGRQGVTNGLID
CCCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCHHHHHH
AVGGETEAIDWLATKGVDAKLKVVEWKDTERRGSFLWSKAMVKTVGSALGLPGYSSDVIH
HCCCCCHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
ELGADRLFLDGLVSVWHP
HHCCCHHHHHHHHHHCCC
>Mature Secondary Structure 
ALRADDLIDRRRLRRKLTFWRVAAIGIVALGVIALSAWFYRDDLGGSTVDHIAKVRIEG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHEEEEC
TITEDEELIKRLEDIRKSSKVKGVILAIDSPGGTTVGGESIYEEVRKVAADKPVVAEVGT
CCCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCHHHHHHH
LAASAGYMIASAADHIVARKTSIVGSIGVLIQYPDVSGLMDKLGIKLEEVKSSPLKASPS
HHHHCCHHHHHHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHCCCHHHHCCCCCCCCCC
PFKPTNDDERAMVRKLILDSYDWFVGIVAERRKMTHEQALALADGSIFTGRQGVTNGLID
CCCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCHHHHHH
AVGGETEAIDWLATKGVDAKLKVVEWKDTERRGSFLWSKAMVKTVGSALGLPGYSSDVIH
HCCCCCHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
ELGADRLFLDGLVSVWHP
HHCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]