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The map label for this gene is nlpI [C]

Identifier: 13472730

GI number: 13472730

Start: 2504392

End: 2505234

Strand: Direct

Name: nlpI [C]

Synonym: mlr3120

Alternate gene names: 13472730

Gene position: 2504392-2505234 (Clockwise)

Preceding gene: 13472729

Following gene: 13472731

Centisome position: 35.59

GC content: 62.63

Gene sequence:

>843_bases
ATGAACGCAATGAGCGTGGAGCGCGGGACCGCATTGCGTGGTTTCGCCCTGACGGCAGCCCTGCTTTCCGGATTGTTGCT
GGCCGGCTGCCAGACATCAGGCCCGACCGGCGAGTTCAACAACATCGACAAGGCGCAGGGGTCGAGCGAGAACATTTCCT
CGCTGTCCGCAGTCATCCAGCGCAATCCCCAGGATCCCGAAGGCTACAATGTGCGCGGCTCGGCCTATGGCCGCGGCGGC
CAGTATCAGGCGGCGCTCAAGGACTTCAACCAGGCCATCCAGCTCAATCCGAATTTCTACCAGGCCTATTCCAACCGCGC
GCTCATCCAGCGCTTCCTCGGCAATCAGGCGGCCGCGCTCGGCGACTATAACAAGTCGATCCAGATCAACGGCAATTATG
ACGCCGCCTATATCGGCCGCGGCAATCTCTACCGCAAGGCGGGCCGCACCCAGGACGCCTTCAACGACTTCCAGAAGGCG
ATCCAGCTCGACACGACGGACGCTCGCGCCTACCACAATCGCGGCCTGATCTATCAGAGCCAGGGCCAGCACAAATTCGC
CATCGAGGATTTCTCGACCGCCATCTCGCTGGCGCCGGATGCAGCCGAGCCCTACAACGGCCGTGGCCTTTCCTATCTGG
CGACGGGCGACGAGGACAACGCCTTCTCCGACTTCAACATGGCCATCAAGCTCGACGGCCAGAACGCTGAGGCCTGGGCC
AATCAGGCGCTCATCTACGAGCGGCGCGGCGACAAGGCGAAGGCCGCGAAATCCTATAAGGAAGCCGTCCGCCTCAACCC
CAATTACCAGCCTGCCAAGGACGGCCTCGCCCGCGTCAGCTGA

Upstream 100 bases:

>100_bases
CGATGCGGAATCGCCGCCACCTTTTTATTTTGATTGTGACCCGGCCCGGAGGGGGGATCCGGACCTGAGCGACGCGGCTT
GAAGTGAGGACAGGGCAGAC

Downstream 100 bases:

>100_bases
TATCAGCTTTAGCAGATCCGGCTAAGCATTGTGGGGACGTTGGCGTGTCCGAAAGGACACGCAGCGCCGAAGATCGCCAC
CGATCCGGCAACCGCGCGTT

Product: O-linked GlcNAc transferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 280; Mature: 280

Protein sequence:

>280_residues
MNAMSVERGTALRGFALTAALLSGLLLAGCQTSGPTGEFNNIDKAQGSSENISSLSAVIQRNPQDPEGYNVRGSAYGRGG
QYQAALKDFNQAIQLNPNFYQAYSNRALIQRFLGNQAAALGDYNKSIQINGNYDAAYIGRGNLYRKAGRTQDAFNDFQKA
IQLDTTDARAYHNRGLIYQSQGQHKFAIEDFSTAISLAPDAAEPYNGRGLSYLATGDEDNAFSDFNMAIKLDGQNAEAWA
NQALIYERRGDKAKAAKSYKEAVRLNPNYQPAKDGLARVS

Sequences:

>Translated_280_residues
MNAMSVERGTALRGFALTAALLSGLLLAGCQTSGPTGEFNNIDKAQGSSENISSLSAVIQRNPQDPEGYNVRGSAYGRGG
QYQAALKDFNQAIQLNPNFYQAYSNRALIQRFLGNQAAALGDYNKSIQINGNYDAAYIGRGNLYRKAGRTQDAFNDFQKA
IQLDTTDARAYHNRGLIYQSQGQHKFAIEDFSTAISLAPDAAEPYNGRGLSYLATGDEDNAFSDFNMAIKLDGQNAEAWA
NQALIYERRGDKAKAAKSYKEAVRLNPNYQPAKDGLARVS
>Mature_280_residues
MNAMSVERGTALRGFALTAALLSGLLLAGCQTSGPTGEFNNIDKAQGSSENISSLSAVIQRNPQDPEGYNVRGSAYGRGG
QYQAALKDFNQAIQLNPNFYQAYSNRALIQRFLGNQAAALGDYNKSIQINGNYDAAYIGRGNLYRKAGRTQDAFNDFQKA
IQLDTTDARAYHNRGLIYQSQGQHKFAIEDFSTAISLAPDAAEPYNGRGLSYLATGDEDNAFSDFNMAIKLDGQNAEAWA
NQALIYERRGDKAKAAKSYKEAVRLNPNYQPAKDGLARVS

Specific function: May Be Involved In Cell Division. Overexpression Of Nlpi Results In The Loss Of The Rod Morphology And The Formation Of Single Prolate Ellipsoids And Pairs Of Prolate Ellipsoids Joined By Partial Constrictions. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Attached To The Membrane By A Lipid Anchor [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 4 TPR repeats [H]

Homologues:

Organism=Homo sapiens, GI32307150, Length=229, Percent_Identity=28.82096069869, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI32307148, Length=229, Percent_Identity=28.82096069869, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI310110582, Length=201, Percent_Identity=32.3383084577114, Blast_Score=92, Evalue=7e-19,
Organism=Homo sapiens, GI310131789, Length=201, Percent_Identity=32.3383084577114, Blast_Score=92, Evalue=7e-19,
Organism=Homo sapiens, GI310123097, Length=201, Percent_Identity=32.3383084577114, Blast_Score=92, Evalue=8e-19,
Organism=Homo sapiens, GI170784867, Length=223, Percent_Identity=27.3542600896861, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI5453980, Length=221, Percent_Identity=26.2443438914027, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI301336134, Length=186, Percent_Identity=24.7311827956989, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI83415184, Length=186, Percent_Identity=24.7311827956989, Blast_Score=65, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI115532692, Length=219, Percent_Identity=31.9634703196347, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI115532690, Length=219, Percent_Identity=31.9634703196347, Blast_Score=99, Evalue=2e-21,
Organism=Drosophila melanogaster, GI17647755, Length=219, Percent_Identity=29.2237442922374, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24585827, Length=219, Percent_Identity=29.2237442922374, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24585829, Length=219, Percent_Identity=29.2237442922374, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24647123, Length=180, Percent_Identity=26.1111111111111, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001440
- InterPro:   IPR013026
- InterPro:   IPR011990
- InterPro:   IPR019734 [H]

Pfam domain/function: PF00515 TPR_1 [H]

EC number: NA

Molecular weight: Translated: 30481; Mature: 30481

Theoretical pI: Translated: 8.75; Mature: 8.75

Prosite motif: PS50005 TPR ; PS50293 TPR_REGION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAMSVERGTALRGFALTAALLSGLLLAGCQTSGPTGEFNNIDKAQGSSENISSLSAVIQ
CCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHCCCCCCHHHHHHHHHH
RNPQDPEGYNVRGSAYGRGGQYQAALKDFNQAIQLNPNFYQAYSNRALIQRFLGNQAAAL
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHEEECCCHHHHHHHHHHHHHHHHCCCHHCC
GDYNKSIQINGNYDAAYIGRGNLYRKAGRTQDAFNDFQKAIQLDTTDARAYHNRGLIYQS
CCCCCEEEEECCCCEEEECCCCHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHCCCCEEEC
QGQHKFAIEDFSTAISLAPDAAEPYNGRGLSYLATGDEDNAFSDFNMAIKLDGQNAEAWA
CCCEEEEHHHHHHHEEECCCCCCCCCCCCEEEEEECCCCCCCCCCEEEEEECCCCHHHHH
NQALIYERRGDKAKAAKSYKEAVRLNPNYQPAKDGLARVS
CCEEEEECCCCHHHHHHHHHHHHCCCCCCCCHHHHHHCCC
>Mature Secondary Structure
MNAMSVERGTALRGFALTAALLSGLLLAGCQTSGPTGEFNNIDKAQGSSENISSLSAVIQ
CCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHCCCCCCHHHHHHHHHH
RNPQDPEGYNVRGSAYGRGGQYQAALKDFNQAIQLNPNFYQAYSNRALIQRFLGNQAAAL
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHEEECCCHHHHHHHHHHHHHHHHCCCHHCC
GDYNKSIQINGNYDAAYIGRGNLYRKAGRTQDAFNDFQKAIQLDTTDARAYHNRGLIYQS
CCCCCEEEEECCCCEEEECCCCHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHCCCCEEEC
QGQHKFAIEDFSTAISLAPDAAEPYNGRGLSYLATGDEDNAFSDFNMAIKLDGQNAEAWA
CCCEEEEHHHHHHHEEECCCCCCCCCCCCEEEEEECCCCCCCCCCEEEEEECCCCHHHHH
NQALIYERRGDKAKAAKSYKEAVRLNPNYQPAKDGLARVS
CCEEEEECCCCHHHHHHHHHHHHCCCCCCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1368342; 8905231 [H]