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The map label for this gene is yngJ [H]

Identifier: 13472711

GI number: 13472711

Start: 2488310

End: 2489542

Strand: Reverse

Name: yngJ [H]

Synonym: mll3094

Alternate gene names: 13472711

Gene position: 2489542-2488310 (Counterclockwise)

Preceding gene: 13472718

Following gene: 13472710

Centisome position: 35.38

GC content: 65.77

Gene sequence:

>1233_bases
ATGAATCTCGGCATGACCGAGCGGCTGAAGCCGATCCACGCGCGCGTCGCGGCCATGGTACGTGACGAGATCATGCCGCT
CGACAAGGAATTCCTGGGCGAGGTGGGCAAGGCGGGCGACCGCTGGGTGTACAGCCCACGCCAGAGTGAAATCCTCGAAG
GGCTGAAGAAGACCGCCAGGGAGCGCGGTCTGTGGAATTTCTGGCTGACCGGCTCCGAACGCGGCTACGGCCTGTCCACC
GTCGAATACGCCTATCTGGCGGAGGAGATGGGCAAGGCGCATCTCGGCGCCGAAACCTTCAACTGCTCGGCGCCCGACAC
CGGCAATATGGAGGTGCTGGAGCGTTACGGCTCGGCCGACCACAAGAAGGAGTGGCTCGAGCCGCTTTTGGATGGAAAAA
TCCGCTCGGCCTATCTGATGACCGAGCCTGATGTCGCCTCGTCCGACGCCACCAACATTGGGATGCGCTGCGAGCGGCAG
GGCGACGATTATGTGCTCAATGGCGAGAAATGGTGGGCCTCGGGGGCCGGCGACCCGCGCTGCGCCATCTACATCGTCAT
GGTGCGGACCGGCGGCGACGGCGAGCCGCAGCACCGCCGCCATTCGATGATCCTGGTGCCTTCCGACACGAAAGGCGTGA
CCAAGCTCCGCGCCATGCAGGTTTACGGCGACGACGACGCGCCGCATGGCCATATGCACCTGCGCTTCGACAATGTGCGT
GTGCCCGCCTCGAACCTGATCCTCGGCGAGGGCAGGGGGTTCGAGATCGCGCAAGGGCGGCTCGGTCCCGGCCGCATACA
TCACTGCATGCGCGCCATCGGTCAGGCCGAGATGGCGCTGGAGATGCTGTGCCAGCGCTCCGTGCGCCGTGAGGCCTTCG
GCCAGAAGCTGGCCAAACTCGGCGCCAATTTCGACATCATCGCCGAATGCCGCATGGAGATCGAGATGGCCCGGCTGCTC
TGCCTCAAGGCGGCGTGGATGATCGACCAGGGCGATGCGCGCGCCGCCGCGCCCTGGATCAGCCAGATCAAGGTCATCGC
GCCGCGCGTCGCGTTGAGGATCACCGACGAGGCGGTGCAGATGTTCGGCGCGCAAGGCATCAGCCAGGACACGCCGCTGG
CGCGGTCGTGGACGCATCTGAGGACATTGCGCCTCGCCGACGGGCCGGACGCCGTGCATCGCCGGCAGGTGGCGCGGACG
GAGCTGAAGAAGTACACGCAGGAGAAGCTCTGA

Upstream 100 bases:

>100_bases
GGGCAAAGAGTTCGCGTTGACAAGGCTATCCGAAGTACGGTCATCCTTGCCACGGGTAAATTGCCGGGCCTCTATGAAGG
GTTAGCGACCGATGACGGAG

Downstream 100 bases:

>100_bases
GCAGCCGCGGCTCTACCATGAGCCTTCTGTCGACAACCAAGGAGTGTCACCGATGACCATTCCCTCCGAAATGAAGGCGT
TGCTCCTGGTCGGCGACGGC

Product: acyl-CoA dehydrogenase

Products: 2,3-dehydroacyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 410; Mature: 410

Protein sequence:

>410_residues
MNLGMTERLKPIHARVAAMVRDEIMPLDKEFLGEVGKAGDRWVYSPRQSEILEGLKKTARERGLWNFWLTGSERGYGLST
VEYAYLAEEMGKAHLGAETFNCSAPDTGNMEVLERYGSADHKKEWLEPLLDGKIRSAYLMTEPDVASSDATNIGMRCERQ
GDDYVLNGEKWWASGAGDPRCAIYIVMVRTGGDGEPQHRRHSMILVPSDTKGVTKLRAMQVYGDDDAPHGHMHLRFDNVR
VPASNLILGEGRGFEIAQGRLGPGRIHHCMRAIGQAEMALEMLCQRSVRREAFGQKLAKLGANFDIIAECRMEIEMARLL
CLKAAWMIDQGDARAAAPWISQIKVIAPRVALRITDEAVQMFGAQGISQDTPLARSWTHLRTLRLADGPDAVHRRQVART
ELKKYTQEKL

Sequences:

>Translated_410_residues
MNLGMTERLKPIHARVAAMVRDEIMPLDKEFLGEVGKAGDRWVYSPRQSEILEGLKKTARERGLWNFWLTGSERGYGLST
VEYAYLAEEMGKAHLGAETFNCSAPDTGNMEVLERYGSADHKKEWLEPLLDGKIRSAYLMTEPDVASSDATNIGMRCERQ
GDDYVLNGEKWWASGAGDPRCAIYIVMVRTGGDGEPQHRRHSMILVPSDTKGVTKLRAMQVYGDDDAPHGHMHLRFDNVR
VPASNLILGEGRGFEIAQGRLGPGRIHHCMRAIGQAEMALEMLCQRSVRREAFGQKLAKLGANFDIIAECRMEIEMARLL
CLKAAWMIDQGDARAAAPWISQIKVIAPRVALRITDEAVQMFGAQGISQDTPLARSWTHLRTLRLADGPDAVHRRQVART
ELKKYTQEKL
>Mature_410_residues
MNLGMTERLKPIHARVAAMVRDEIMPLDKEFLGEVGKAGDRWVYSPRQSEILEGLKKTARERGLWNFWLTGSERGYGLST
VEYAYLAEEMGKAHLGAETFNCSAPDTGNMEVLERYGSADHKKEWLEPLLDGKIRSAYLMTEPDVASSDATNIGMRCERQ
GDDYVLNGEKWWASGAGDPRCAIYIVMVRTGGDGEPQHRRHSMILVPSDTKGVTKLRAMQVYGDDDAPHGHMHLRFDNVR
VPASNLILGEGRGFEIAQGRLGPGRIHHCMRAIGQAEMALEMLCQRSVRREAFGQKLAKLGANFDIIAECRMEIEMARLL
CLKAAWMIDQGDARAAAPWISQIKVIAPRVALRITDEAVQMFGAQGISQDTPLARSWTHLRTLRLADGPDAVHRRQVART
ELKKYTQEKL

Specific function: Unknown

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI38505218, Length=402, Percent_Identity=49.5024875621891, Blast_Score=387, Evalue=1e-107,
Organism=Homo sapiens, GI48976061, Length=405, Percent_Identity=48.3950617283951, Blast_Score=373, Evalue=1e-103,
Organism=Homo sapiens, GI211971008, Length=405, Percent_Identity=48.3950617283951, Blast_Score=373, Evalue=1e-103,
Organism=Homo sapiens, GI4557231, Length=410, Percent_Identity=27.3170731707317, Blast_Score=149, Evalue=4e-36,
Organism=Homo sapiens, GI187960098, Length=406, Percent_Identity=27.3399014778325, Blast_Score=149, Evalue=5e-36,
Organism=Homo sapiens, GI4557233, Length=337, Percent_Identity=27.893175074184, Blast_Score=116, Evalue=4e-26,
Organism=Homo sapiens, GI7656849, Length=350, Percent_Identity=26.5714285714286, Blast_Score=109, Evalue=5e-24,
Organism=Homo sapiens, GI21361497, Length=399, Percent_Identity=27.0676691729323, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI4501859, Length=361, Percent_Identity=24.6537396121884, Blast_Score=102, Evalue=5e-22,
Organism=Homo sapiens, GI226958412, Length=328, Percent_Identity=24.0853658536585, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI226958414, Length=328, Percent_Identity=24.0853658536585, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI4501857, Length=312, Percent_Identity=27.2435897435897, Blast_Score=91, Evalue=1e-18,
Organism=Escherichia coli, GI87081958, Length=316, Percent_Identity=25.6329113924051, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1786223, Length=269, Percent_Identity=24.5353159851301, Blast_Score=70, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17562446, Length=406, Percent_Identity=45.8128078817734, Blast_Score=360, Evalue=1e-100,
Organism=Caenorhabditis elegans, GI17570075, Length=418, Percent_Identity=26.7942583732057, Blast_Score=135, Evalue=4e-32,
Organism=Caenorhabditis elegans, GI17533517, Length=360, Percent_Identity=27.2222222222222, Blast_Score=122, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI17569725, Length=362, Percent_Identity=25.1381215469613, Blast_Score=121, Evalue=8e-28,
Organism=Caenorhabditis elegans, GI17534899, Length=410, Percent_Identity=23.6585365853659, Blast_Score=117, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17508101, Length=352, Percent_Identity=25.8522727272727, Blast_Score=102, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI71985184, Length=387, Percent_Identity=26.6149870801034, Blast_Score=98, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI17505929, Length=334, Percent_Identity=25.4491017964072, Blast_Score=95, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI17551932, Length=334, Percent_Identity=23.9520958083832, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17538396, Length=358, Percent_Identity=24.0223463687151, Blast_Score=93, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17506239, Length=343, Percent_Identity=25.3644314868805, Blast_Score=92, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI71990804, Length=288, Percent_Identity=28.4722222222222, Blast_Score=85, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17534353, Length=335, Percent_Identity=26.5671641791045, Blast_Score=79, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI71985192, Length=249, Percent_Identity=27.3092369477912, Blast_Score=78, Evalue=8e-15,
Organism=Drosophila melanogaster, GI24660351, Length=400, Percent_Identity=27.5, Blast_Score=134, Evalue=1e-31,
Organism=Drosophila melanogaster, GI21356377, Length=337, Percent_Identity=28.1899109792285, Blast_Score=123, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24646207, Length=348, Percent_Identity=26.4367816091954, Blast_Score=112, Evalue=5e-25,
Organism=Drosophila melanogaster, GI24666513, Length=404, Percent_Identity=24.2574257425743, Blast_Score=101, Evalue=7e-22,
Organism=Drosophila melanogaster, GI281363737, Length=357, Percent_Identity=26.3305322128852, Blast_Score=95, Evalue=1e-19,
Organism=Drosophila melanogaster, GI21355753, Length=338, Percent_Identity=23.9644970414201, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI19920834, Length=328, Percent_Identity=26.219512195122, Blast_Score=73, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.3

Molecular weight: Translated: 45914; Mature: 45914

Theoretical pI: Translated: 7.85; Mature: 7.85

Prosite motif: PS00639 THIOL_PROTEASE_HIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLGMTERLKPIHARVAAMVRDEIMPLDKEFLGEVGKAGDRWVYSPRQSEILEGLKKTAR
CCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCEEECCCHHHHHHHHHHHHH
ERGLWNFWLTGSERGYGLSTVEYAYLAEEMGKAHLGAETFNCSAPDTGNMEVLERYGSAD
HCCCEEEEEECCCCCCCCCHHHHHHHHHHHCHHHCCCCCEECCCCCCCCHHHHHHHCCCC
HKKEWLEPLLDGKIRSAYLMTEPDVASSDATNIGMRCERQGDDYVLNGEKWWASGAGDPR
HHHHHHHHHHCCCHHEEEEEECCCCCCCCCCCCCCEEECCCCCEEECCCEEEECCCCCCC
CAIYIVMVRTGGDGEPQHRRHSMILVPSDTKGVTKLRAMQVYGDDDAPHGHMHLRFDNVR
EEEEEEEEEECCCCCCCHHCCCEEEEECCCCCHHHEEEEEEECCCCCCCCEEEEEECCEE
VPASNLILGEGRGFEIAQGRLGPGRIHHCMRAIGQAEMALEMLCQRSVRREAFGQKLAKL
CCCCCEEEECCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GANFDIIAECRMEIEMARLLCLKAAWMIDQGDARAAAPWISQIKVIAPRVALRITDEAVQ
CCCCEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCEEEEECHHHHH
MFGAQGISQDTPLARSWTHLRTLRLADGPDAVHRRQVARTELKKYTQEKL
HHCCCCCCCCCCCHHHHHHHEEEEECCCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNLGMTERLKPIHARVAAMVRDEIMPLDKEFLGEVGKAGDRWVYSPRQSEILEGLKKTAR
CCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCEEECCCHHHHHHHHHHHHH
ERGLWNFWLTGSERGYGLSTVEYAYLAEEMGKAHLGAETFNCSAPDTGNMEVLERYGSAD
HCCCEEEEEECCCCCCCCCHHHHHHHHHHHCHHHCCCCCEECCCCCCCCHHHHHHHCCCC
HKKEWLEPLLDGKIRSAYLMTEPDVASSDATNIGMRCERQGDDYVLNGEKWWASGAGDPR
HHHHHHHHHHCCCHHEEEEEECCCCCCCCCCCCCCEEECCCCCEEECCCEEEECCCCCCC
CAIYIVMVRTGGDGEPQHRRHSMILVPSDTKGVTKLRAMQVYGDDDAPHGHMHLRFDNVR
EEEEEEEEEECCCCCCCHHCCCEEEEECCCCCHHHEEEEEEECCCCCCCCEEEEEECCEE
VPASNLILGEGRGFEIAQGRLGPGRIHHCMRAIGQAEMALEMLCQRSVRREAFGQKLAKL
CCCCCEEEECCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GANFDIIAECRMEIEMARLLCLKAAWMIDQGDARAAAPWISQIKVIAPRVALRITDEAVQ
CCCCEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCEEEEECHHHHH
MFGAQGISQDTPLARSWTHLRTLRLADGPDAVHRRQVARTELKKYTQEKL
HHCCCCCCCCCCCHHHHHHHEEEEECCCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acceptor

Specific reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9387222; 9384377 [H]