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The map label for this gene is pabB [H]

Identifier: 13472643

GI number: 13472643

Start: 2412976

End: 2414121

Strand: Direct

Name: pabB [H]

Synonym: mlr3005

Alternate gene names: 13472643

Gene position: 2412976-2414121 (Clockwise)

Preceding gene: 13472642

Following gene: 13472644

Centisome position: 34.29

GC content: 64.92

Gene sequence:

>1146_bases
ATGTCCCTGCCCGCCGCCATTTTCCGCAACGACGAAAGCGCGCGTCAGCTCGTGTTCGACCGGCCGGCCGATATCATCGT
GGCGCATGAGGCCCGGGATTTCGGGGCGGCGCTGGAAGCAGTGCAGGCCGCGCACGACGCCGGCAAATGGCTGGCCGGCT
ATTTCTCCTACGAGGCCGGTTATCTGCTCGAACCGAAACTCGTTCCCTTGCTGCCGCGGGAACGTCGCGCGCCGTTGATC
TGCCTCGGTGTCTTCGATGCTCCGGTCGAAGAAGCGGTGCCGCCACGCAACGCAGCAACCCCGAACGGCCCGATCTTCGA
CGCGCGGGCGACGTGGTCTTTCGAGGACTATGAAAAGCGCTTCTCGCGGCTGCACCAGCACATCAGGCAAGGCGACTGCT
ACCAGGGCAATCTGACTTTTCCGGTGCAGGCGCAATGGTCCGGCGACCCGCTTGCCGCCTTCGACGCGCTGACCGAACGC
CAGCCGGTAAAGTATGGCGCGCTGGTGGCGCTGGGCGATCCCGTCGTGCTGTCGCGCTCGCCCGAACTGTTCTTCGAGAT
CAACGGCGCCGGGATGATCGAGACGCATCCAATGAAGGGCACTGCCCCGCGCGGCGCGACCAAGGCCGAGGATGAGCGGC
AGAAGACCTTCCTGCGCAATGACGAGAAGAACCAGGCCGAGAACCGGATGATCGTCGACCTCTTGCGCAACGACATTTCG
CTGATCAGCGAGGTCGGCACGCTGGAGGTGCCGGAACTGTTCCGCATCGAGAGCTACCCGACCGTCCACCAGATGGTGAG
CGACGTCAGGGCGAAGCTGCTGCCGGGCCTCACCATCCGCGAGGTGTTTGCGGCACTGTTTCCTTGCGGCTCGATCACCG
GCGCGCCGAAGATCCGCGCCATGGAGATCCTGCACGATCTGGAGGGCGCGCCGCGCGATGTCTATTGCGGCGCCATCGGC
TGGATCGCACCGGGCGGCACGATGCGCTTTTCCGTGGCGATCCGCACCATCTCGCTCTTTGCCAGCGGCGAGGCCGTCTA
CAATGTCGGCGGCGGCATCGTCTTCGATTCGACGCCTGAGGAGGAGTATCAGGAGTGCCTGCTCAAAGCCCGCTTCGCGA
CGGGGACACCGCCGATTTCGAGCTGA

Upstream 100 bases:

>100_bases
GCCAAAAGGTCGGCTTTGAGGGGCAGGGTGCCGTTCCCTCGATTGCACGCGAGCGGCCCCCCATATAGAGCGATCGACGG
CTTCATCGATCCTGGTCCCC

Downstream 100 bases:

>100_bases
TCGAAACCATGCGCTGGCAGCCCGGGACGAGCTTCCTGCGCTTCGATCGCCACCTTGCACGCCTCTATGGCTCGGCGGCG
GAGCTCGGCTTCGCCTGTGA

Product: aminodeoxychorismate synthase

Products: NA

Alternate protein names: ADC synthase; Para-aminobenzoate synthase component I [H]

Number of amino acids: Translated: 381; Mature: 380

Protein sequence:

>381_residues
MSLPAAIFRNDESARQLVFDRPADIIVAHEARDFGAALEAVQAAHDAGKWLAGYFSYEAGYLLEPKLVPLLPRERRAPLI
CLGVFDAPVEEAVPPRNAATPNGPIFDARATWSFEDYEKRFSRLHQHIRQGDCYQGNLTFPVQAQWSGDPLAAFDALTER
QPVKYGALVALGDPVVLSRSPELFFEINGAGMIETHPMKGTAPRGATKAEDERQKTFLRNDEKNQAENRMIVDLLRNDIS
LISEVGTLEVPELFRIESYPTVHQMVSDVRAKLLPGLTIREVFAALFPCGSITGAPKIRAMEILHDLEGAPRDVYCGAIG
WIAPGGTMRFSVAIRTISLFASGEAVYNVGGGIVFDSTPEEEYQECLLKARFATGTPPISS

Sequences:

>Translated_381_residues
MSLPAAIFRNDESARQLVFDRPADIIVAHEARDFGAALEAVQAAHDAGKWLAGYFSYEAGYLLEPKLVPLLPRERRAPLI
CLGVFDAPVEEAVPPRNAATPNGPIFDARATWSFEDYEKRFSRLHQHIRQGDCYQGNLTFPVQAQWSGDPLAAFDALTER
QPVKYGALVALGDPVVLSRSPELFFEINGAGMIETHPMKGTAPRGATKAEDERQKTFLRNDEKNQAENRMIVDLLRNDIS
LISEVGTLEVPELFRIESYPTVHQMVSDVRAKLLPGLTIREVFAALFPCGSITGAPKIRAMEILHDLEGAPRDVYCGAIG
WIAPGGTMRFSVAIRTISLFASGEAVYNVGGGIVFDSTPEEEYQECLLKARFATGTPPISS
>Mature_380_residues
SLPAAIFRNDESARQLVFDRPADIIVAHEARDFGAALEAVQAAHDAGKWLAGYFSYEAGYLLEPKLVPLLPRERRAPLIC
LGVFDAPVEEAVPPRNAATPNGPIFDARATWSFEDYEKRFSRLHQHIRQGDCYQGNLTFPVQAQWSGDPLAAFDALTERQ
PVKYGALVALGDPVVLSRSPELFFEINGAGMIETHPMKGTAPRGATKAEDERQKTFLRNDEKNQAENRMIVDLLRNDISL
ISEVGTLEVPELFRIESYPTVHQMVSDVRAKLLPGLTIREVFAALFPCGSITGAPKIRAMEILHDLEGAPRDVYCGAIGW
IAPGGTMRFSVAIRTISLFASGEAVYNVGGGIVFDSTPEEEYQECLLKARFATGTPPISS

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine [H]

COG id: COG0147

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate synthase component I family [H]

Homologues:

Organism=Escherichia coli, GI1788114, Length=263, Percent_Identity=41.8250950570342, Blast_Score=206, Evalue=2e-54,
Organism=Escherichia coli, GI1787518, Length=294, Percent_Identity=30.2721088435374, Blast_Score=125, Evalue=5e-30,
Organism=Escherichia coli, GI1786809, Length=217, Percent_Identity=25.3456221198157, Blast_Score=65, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6320935, Length=256, Percent_Identity=38.671875, Blast_Score=169, Evalue=1e-42,
Organism=Saccharomyces cerevisiae, GI6324361, Length=279, Percent_Identity=29.7491039426523, Blast_Score=100, Evalue=5e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR019999
- InterPro:   IPR006805
- InterPro:   IPR015890
- InterPro:   IPR005802 [H]

Pfam domain/function: PF04715 Anth_synt_I_N; PF00425 Chorismate_bind [H]

EC number: =2.6.1.85 [H]

Molecular weight: Translated: 41875; Mature: 41744

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLPAAIFRNDESARQLVFDRPADIIVAHEARDFGAALEAVQAAHDAGKWLAGYFSYEAG
CCCCCHHHCCCHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
YLLEPKLVPLLPRERRAPLICLGVFDAPVEEAVPPRNAATPNGPIFDARATWSFEDYEKR
EEECCCCCCCCCCCCCCCEEEEECCCCCHHHCCCCCCCCCCCCCEEECEECCCHHHHHHH
FSRLHQHIRQGDCYQGNLTFPVQAQWSGDPLAAFDALTERQPVKYGALVALGDPVVLSRS
HHHHHHHHHCCCCCCCCEEEEEEECCCCCCHHHHHHHHCCCCCCCCEEEEECCCEEEECC
PELFFEINGAGMIETHPMKGTAPRGATKAEDERQKTFLRNDEKNQAENRMIVDLLRNDIS
CCEEEEECCCCEEEECCCCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
LISEVGTLEVPELFRIESYPTVHQMVSDVRAKLLPGLTIREVFAALFPCGSITGAPKIRA
HHHHCCCCCCCHHHEECCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCHHH
MEILHDLEGAPRDVYCGAIGWIAPGGTMRFSVAIRTISLFASGEAVYNVGGGIVFDSTPE
HHHHHHHCCCCCEEEECEEEEECCCCCEEEEEEEEEEEEEECCCEEEECCCEEEECCCCH
EEYQECLLKARFATGTPPISS
HHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
SLPAAIFRNDESARQLVFDRPADIIVAHEARDFGAALEAVQAAHDAGKWLAGYFSYEAG
CCCCHHHCCCHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
YLLEPKLVPLLPRERRAPLICLGVFDAPVEEAVPPRNAATPNGPIFDARATWSFEDYEKR
EEECCCCCCCCCCCCCCCEEEEECCCCCHHHCCCCCCCCCCCCCEEECEECCCHHHHHHH
FSRLHQHIRQGDCYQGNLTFPVQAQWSGDPLAAFDALTERQPVKYGALVALGDPVVLSRS
HHHHHHHHHCCCCCCCCEEEEEEECCCCCCHHHHHHHHCCCCCCCCEEEEECCCEEEECC
PELFFEINGAGMIETHPMKGTAPRGATKAEDERQKTFLRNDEKNQAENRMIVDLLRNDIS
CCEEEEECCCCEEEECCCCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
LISEVGTLEVPELFRIESYPTVHQMVSDVRAKLLPGLTIREVFAALFPCGSITGAPKIRA
HHHHCCCCCCCHHHEECCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCHHH
MEILHDLEGAPRDVYCGAIGWIAPGGTMRFSVAIRTISLFASGEAVYNVGGGIVFDSTPE
HHHHHHHCCCCCEEEECEEEEECCCCCEEEEEEEEEEEEEECCCEEEECCCEEEECCCCH
EEYQECLLKARFATGTPPISS
HHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3057324; 2251281 [H]