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The map label for this gene is clcB [H]

Identifier: 13472607

GI number: 13472607

Start: 2375971

End: 2377752

Strand: Reverse

Name: clcB [H]

Synonym: mll2953

Alternate gene names: 13472607

Gene position: 2377752-2375971 (Counterclockwise)

Preceding gene: 13472608

Following gene: 13472606

Centisome position: 33.79

GC content: 66.89

Gene sequence:

>1782_bases
GTGCTTTCCAGAAACCAGCCACAAGTCTATGCCCGCCGGCTGCGTGCGGTGCTGCTGCGGTCAATTCCGCTGCTCGAGGC
GCGCGGCATCGCCGTGGTCATCCTGGCGGGCGTCGTCGGGGTGATGGCGGGCATACTGGTCACGGCGATGAGCCAGATCG
TGCAGGATCTGCACGGGCTGTTGTTCGGCGTTCAACCCGGCGGCCGGCTTTCCGGCATGTTCTCGCTCGCCAATCCCATG
CAGGCGCTGATCCCGGCGGTCGGCGGCGCCCTGCTCGGATTGACGGTGATCTGGCTGCGGCTGCGGAAATTCCGCACTCC
GGTCGATCCGATCGAGGCCAACGCGCTCTATGGCGGGCGCATGTCGCTGACCGACACCTTCATCATCGCCGGCCAGACCA
TGATCTCCAGCGGCTTCGGCGCCTCGGTCGGCCTGGAAGCCGGCTACACGCAGGTCGGATCCGGCCTGGCGTCGCGGCTG
GCGCGCATCTTCCGGCTGCGCCGCAACGATGTCCGTGTCCTTGTCGGCTGCGGCGCGGCCGGCGCCATCGCCGCCGCTTT
CGACGCGCCGCTTACCGGCGCCTTCTACGGTTTCGAACTGGTCATCGGCATCTACTCGGTCGCCAATGTCGCGCCTGTCA
TGACTGCGGCGATCTCCGCCTCGCTGACGGCGGAAATGTTCGGCGGCGTGCCGTTTCCGTTGGAGCTTTCAGGGCTGCCG
CAACTCACCCCCAGCCAGTATGTGCCGTTCCTGCTGCTCGGGCTGCTGGGCGGCGCGGCCTCGATCGCCATCATGCAGTT
GGTGACGCTGATCGAACGCGGTTTCAACAGGCTGTCGGTCGATGCCTCGCTGCGCCCCGTCATCGGCGGCGTCATCGTCG
GCCTGCTGGGATTGATCACGCCGCAGGTGCTGTCCAGCGGCCATGGCGCGCTGCACCGCGAATTCGCCATGAACTATGGG
CTGACCGTTGTGGCCAGCGTCTTCGTGCTGAAGCTGGCGGCGTCAGCCATCTCGCTGGGCTCGGGCTTTCGCGGCGGCTT
GTTCTTTGCCTCGCTGTTCCTCGGCGCGCTGCTCGGCAAGGCATTCGCCGGCGTGATGGCGCTGATTTCGCCGGCGACCG
GCATCGACCCTTCGGTTGCCGCTGTCGTCGGCATGACCTCGCTTGCCGTCGGTGTCGTCGGCGGCCCGCTGACGATGACC
TTCCTGGCGCTGGAATCGACCCGCGACCTGACGCTCACCGGCGTCGTGCTGGCCGCCTCGATCATGGCGGCGATCCTGGT
GCGCGAAACCTTCGGTTATTCGTTCTCGACATGGCGCTTCCACCTGCGCGGCGAGACGATCCGCAGCGCCCATGATGTCG
GCTGGATGCGGAGCCTCACCGTCGGCTCGATGATGCGCAAGGACATCAAGACCATCGATGCCTCGACGACACTGGCCGAC
TTCCGCAAGCAGATCCCACTGGGTTCGGCGCAGCGCGTCATCGCCGTCGACCCGGGCGATCAGTATGTCGGCGTGCTGAT
CGTGGCCGAACTGCACAGCGATCCCGCCGGCGGCGAGGTGCCGGTGCGCGATCTCGCCCAGTACAAGGATGCCGTCCTGG
TGCCCAGCATGAACGTGCAGGCCGCTGCCGAAACATTCCAGCGCGCCGGCGCCGAGGAACTGGCGGTCGTCGAGGATTTC
ACCGACCGCATCGTGCTCGGCCTGCTGACCGAGGGCCATCTGATGCGGCGCTATGCCGAGGAACTCGAAAAGGCGCGCCG
GGATCTGTCGGGCGAGGGCTAA

Upstream 100 bases:

>100_bases
AAAACGATCCTCGCAGCGGGGAGCCGGCATCGCGGTTGCCATGCGGTATCGCCGGGCGTATCAGCCTTCTGCGTTCTTTT
GATATCGGCGAGCCGCCCGA

Downstream 100 bases:

>100_bases
GGCTTCTCCCTACGCGTCCGTGTTAATCGGCGGCGCGGCTTACTCGCGTGACCCCTCCTGGCCCAGCTATTGGCCCCATG
CTGGCGCCCTTGCGTAGCTT

Product: chloride channel protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 593; Mature: 593

Protein sequence:

>593_residues
MLSRNQPQVYARRLRAVLLRSIPLLEARGIAVVILAGVVGVMAGILVTAMSQIVQDLHGLLFGVQPGGRLSGMFSLANPM
QALIPAVGGALLGLTVIWLRLRKFRTPVDPIEANALYGGRMSLTDTFIIAGQTMISSGFGASVGLEAGYTQVGSGLASRL
ARIFRLRRNDVRVLVGCGAAGAIAAAFDAPLTGAFYGFELVIGIYSVANVAPVMTAAISASLTAEMFGGVPFPLELSGLP
QLTPSQYVPFLLLGLLGGAASIAIMQLVTLIERGFNRLSVDASLRPVIGGVIVGLLGLITPQVLSSGHGALHREFAMNYG
LTVVASVFVLKLAASAISLGSGFRGGLFFASLFLGALLGKAFAGVMALISPATGIDPSVAAVVGMTSLAVGVVGGPLTMT
FLALESTRDLTLTGVVLAASIMAAILVRETFGYSFSTWRFHLRGETIRSAHDVGWMRSLTVGSMMRKDIKTIDASTTLAD
FRKQIPLGSAQRVIAVDPGDQYVGVLIVAELHSDPAGGEVPVRDLAQYKDAVLVPSMNVQAAAETFQRAGAEELAVVEDF
TDRIVLGLLTEGHLMRRYAEELEKARRDLSGEG

Sequences:

>Translated_593_residues
MLSRNQPQVYARRLRAVLLRSIPLLEARGIAVVILAGVVGVMAGILVTAMSQIVQDLHGLLFGVQPGGRLSGMFSLANPM
QALIPAVGGALLGLTVIWLRLRKFRTPVDPIEANALYGGRMSLTDTFIIAGQTMISSGFGASVGLEAGYTQVGSGLASRL
ARIFRLRRNDVRVLVGCGAAGAIAAAFDAPLTGAFYGFELVIGIYSVANVAPVMTAAISASLTAEMFGGVPFPLELSGLP
QLTPSQYVPFLLLGLLGGAASIAIMQLVTLIERGFNRLSVDASLRPVIGGVIVGLLGLITPQVLSSGHGALHREFAMNYG
LTVVASVFVLKLAASAISLGSGFRGGLFFASLFLGALLGKAFAGVMALISPATGIDPSVAAVVGMTSLAVGVVGGPLTMT
FLALESTRDLTLTGVVLAASIMAAILVRETFGYSFSTWRFHLRGETIRSAHDVGWMRSLTVGSMMRKDIKTIDASTTLAD
FRKQIPLGSAQRVIAVDPGDQYVGVLIVAELHSDPAGGEVPVRDLAQYKDAVLVPSMNVQAAAETFQRAGAEELAVVEDF
TDRIVLGLLTEGHLMRRYAEELEKARRDLSGEG
>Mature_593_residues
MLSRNQPQVYARRLRAVLLRSIPLLEARGIAVVILAGVVGVMAGILVTAMSQIVQDLHGLLFGVQPGGRLSGMFSLANPM
QALIPAVGGALLGLTVIWLRLRKFRTPVDPIEANALYGGRMSLTDTFIIAGQTMISSGFGASVGLEAGYTQVGSGLASRL
ARIFRLRRNDVRVLVGCGAAGAIAAAFDAPLTGAFYGFELVIGIYSVANVAPVMTAAISASLTAEMFGGVPFPLELSGLP
QLTPSQYVPFLLLGLLGGAASIAIMQLVTLIERGFNRLSVDASLRPVIGGVIVGLLGLITPQVLSSGHGALHREFAMNYG
LTVVASVFVLKLAASAISLGSGFRGGLFFASLFLGALLGKAFAGVMALISPATGIDPSVAAVVGMTSLAVGVVGGPLTMT
FLALESTRDLTLTGVVLAASIMAAILVRETFGYSFSTWRFHLRGETIRSAHDVGWMRSLTVGSMMRKDIKTIDASTTLAD
FRKQIPLGSAQRVIAVDPGDQYVGVLIVAELHSDPAGGEVPVRDLAQYKDAVLVPSMNVQAAAETFQRAGAEELAVVEDF
TDRIVLGLLTEGHLMRRYAEELEKARRDLSGEG

Specific function: Probably acts as an electrical shunt for an outwardly- directed proton pump that is linked to amino acid decarboxylation, as part of the extreme acid resistance (XAR) response [H]

COG id: COG0038

COG function: function code P; Chloride channel protein EriC

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chloride channel (TC 2.A.49) family. ClcB subfamily [H]

Homologues:

Organism=Escherichia coli, GI87081943, Length=402, Percent_Identity=26.3681592039801, Blast_Score=86, Evalue=8e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014743
- InterPro:   IPR001807 [H]

Pfam domain/function: PF00654 Voltage_CLC [H]

EC number: NA

Molecular weight: Translated: 62208; Mature: 62208

Theoretical pI: Translated: 9.42; Mature: 9.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSRNQPQVYARRLRAVLLRSIPLLEARGIAVVILAGVVGVMAGILVTAMSQIVQDLHGL
CCCCCCHHHHHHHHHHHHHHHCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LFGVQPGGRLSGMFSLANPMQALIPAVGGALLGLTVIWLRLRKFRTPVDPIEANALYGGR
EEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEECCC
MSLTDTFIIAGQTMISSGFGASVGLEAGYTQVGSGLASRLARIFRLRRNDVRVLVGCGAA
CCCCCEEEEECHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCH
GAIAAAFDAPLTGAFYGFELVIGIYSVANVAPVMTAAISASLTAEMFGGVPFPLELSGLP
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCC
QLTPSQYVPFLLLGLLGGAASIAIMQLVTLIERGFNRLSVDASLRPVIGGVIVGLLGLIT
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHH
PQVLSSGHGALHREFAMNYGLTVVASVFVLKLAASAISLGSGFRGGLFFASLFLGALLGK
HHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
AFAGVMALISPATGIDPSVAAVVGMTSLAVGVVGGPLTMTFLALESTRDLTLTGVVLAAS
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHH
IMAAILVRETFGYSFSTWRFHLRGETIRSAHDVGWMRSLTVGSMMRKDIKTIDASTTLAD
HHHHHHHHHHHCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
FRKQIPLGSAQRVIAVDPGDQYVGVLIVAELHSDPAGGEVPVRDLAQYKDAVLVPSMNVQ
HHHHCCCCCCCEEEEECCCCCEEEEEEEEEECCCCCCCCCCHHHHHHHCCEEECCCCCHH
AAAETFQRAGAEELAVVEDFTDRIVLGLLTEGHLMRRYAEELEKARRDLSGEG
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MLSRNQPQVYARRLRAVLLRSIPLLEARGIAVVILAGVVGVMAGILVTAMSQIVQDLHGL
CCCCCCHHHHHHHHHHHHHHHCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LFGVQPGGRLSGMFSLANPMQALIPAVGGALLGLTVIWLRLRKFRTPVDPIEANALYGGR
EEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEECCC
MSLTDTFIIAGQTMISSGFGASVGLEAGYTQVGSGLASRLARIFRLRRNDVRVLVGCGAA
CCCCCEEEEECHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCH
GAIAAAFDAPLTGAFYGFELVIGIYSVANVAPVMTAAISASLTAEMFGGVPFPLELSGLP
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCC
QLTPSQYVPFLLLGLLGGAASIAIMQLVTLIERGFNRLSVDASLRPVIGGVIVGLLGLIT
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHH
PQVLSSGHGALHREFAMNYGLTVVASVFVLKLAASAISLGSGFRGGLFFASLFLGALLGK
HHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
AFAGVMALISPATGIDPSVAAVVGMTSLAVGVVGGPLTMTFLALESTRDLTLTGVVLAAS
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHH
IMAAILVRETFGYSFSTWRFHLRGETIRSAHDVGWMRSLTVGSMMRKDIKTIDASTTLAD
HHHHHHHHHHHCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
FRKQIPLGSAQRVIAVDPGDQYVGVLIVAELHSDPAGGEVPVRDLAQYKDAVLVPSMNVQ
HHHHCCCCCCCEEEEECCCCCEEEEEEEEEECCCCCCCCCCHHHHHHHCCEEECCCCCHH
AAAETFQRAGAEELAVVEDFTDRIVLGLLTEGHLMRRYAEELEKARRDLSGEG
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA