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The map label for this gene is yafC [H]

Identifier: 13472475

GI number: 13472475

Start: 2235024

End: 2235947

Strand: Reverse

Name: yafC [H]

Synonym: mll2784

Alternate gene names: 13472475

Gene position: 2235947-2235024 (Counterclockwise)

Preceding gene: 13472477

Following gene: 13472470

Centisome position: 31.78

GC content: 64.29

Gene sequence:

>924_bases
ATGGATCGTCTCAGTGGCCTCCTGGCCTTCGCCCGTACCGCCGAGCTCGGCAGTTTCATCGCTGCCGGCCGGGCGCTCGG
CATTTCGGCCTCCGCCGTCGGCAAAAGCGTCGCCAGGCTCGAACAGGAGCTCGGCGTCCGGCTCCTGCAGCGCAGCACGC
GACGCGTTGGCCTGACGGAAGAGGGCAGGCTGTTCAACGAGCGGGTGCGGCGCATTCTCGACGACATCGACGATGCCGAG
GCGATGCTGTCGCGGACGCGGGAGACGCCGCACGGACGGCTGCGCGTCTCGACTCCGATCGTCACCTACCATCTGCTTTT
GCCGGTGCTGTCGGAGTTCATGTCCCGCTATCCCGAGATCGAACTCGACATCGATTTCAACGACCGCATCGTCGACGTCA
TCGAGGAAGGCATCGACGTCGCGATCCGCAGCGGCGAGCTGCCCGATTCACGATTGGTGTCGAGACCCGTTGGACCCTTT
CGCATGCTTTTGTGCGCGGCGCCCTCCTATCTCGAGCGCCACGGCACGCCCGGCGAGCCGGCGGACCTCATCCGGCATTT
CGGCATAAATTTCCGCTTTCTCAACAGCGGCAGGCTGCTTGAATGGCCATTCATCACCGGAAGCGCCGAACCGCAGATAC
GCTCGAAGCTGACCTGCAACAATATGGAAGCCTTGAAGGGCGCCACGATCGCCGGGCTCGGCATCGCCTGCATGCCGGAT
TTCCTGGTCCGCGAGGCGCTGCTGGACGGAAGGCTGCGCACGGTGCTGGACGATCATATCGACGGCCGTGGCCAGTTCCG
GATGCTGTGGCCCTCCAATCGCCATCTGTCGCCAAAAGTTCGCGTCTTCGTCGATTTCCTTCCCGAGCGGCTTGCGGCGG
CGCCGAATACAGCGGCGGTGAAGAGTGGGCACCGAAAGCGCTGA

Upstream 100 bases:

>100_bases
GGCGCCGGTCGCAAGGACAAGATAGGTCAAGGACCTTTCCGGAAAAATGGTATTATATCTCCTGATATACCGGACTGAAA
CGCTCGAATGGAAGACTGTG

Downstream 100 bases:

>100_bases
AGCCTGTCAGTCCCTGATGCTTCTGGCCACCAGCCGGGCGACGCTCGGGCCGACGAGCAGCACGATCAGGAAGCGGGCCG
ATTGCAGCGCCATGACGAAG

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 307; Mature: 307

Protein sequence:

>307_residues
MDRLSGLLAFARTAELGSFIAAGRALGISASAVGKSVARLEQELGVRLLQRSTRRVGLTEEGRLFNERVRRILDDIDDAE
AMLSRTRETPHGRLRVSTPIVTYHLLLPVLSEFMSRYPEIELDIDFNDRIVDVIEEGIDVAIRSGELPDSRLVSRPVGPF
RMLLCAAPSYLERHGTPGEPADLIRHFGINFRFLNSGRLLEWPFITGSAEPQIRSKLTCNNMEALKGATIAGLGIACMPD
FLVREALLDGRLRTVLDDHIDGRGQFRMLWPSNRHLSPKVRVFVDFLPERLAAAPNTAAVKSGHRKR

Sequences:

>Translated_307_residues
MDRLSGLLAFARTAELGSFIAAGRALGISASAVGKSVARLEQELGVRLLQRSTRRVGLTEEGRLFNERVRRILDDIDDAE
AMLSRTRETPHGRLRVSTPIVTYHLLLPVLSEFMSRYPEIELDIDFNDRIVDVIEEGIDVAIRSGELPDSRLVSRPVGPF
RMLLCAAPSYLERHGTPGEPADLIRHFGINFRFLNSGRLLEWPFITGSAEPQIRSKLTCNNMEALKGATIAGLGIACMPD
FLVREALLDGRLRTVLDDHIDGRGQFRMLWPSNRHLSPKVRVFVDFLPERLAAAPNTAAVKSGHRKR
>Mature_307_residues
MDRLSGLLAFARTAELGSFIAAGRALGISASAVGKSVARLEQELGVRLLQRSTRRVGLTEEGRLFNERVRRILDDIDDAE
AMLSRTRETPHGRLRVSTPIVTYHLLLPVLSEFMSRYPEIELDIDFNDRIVDVIEEGIDVAIRSGELPDSRLVSRPVGPF
RMLLCAAPSYLERHGTPGEPADLIRHFGINFRFLNSGRLLEWPFITGSAEPQIRSKLTCNNMEALKGATIAGLGIACMPD
FLVREALLDGRLRTVLDDHIDGRGQFRMLWPSNRHLSPKVRVFVDFLPERLAAAPNTAAVKSGHRKR

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=296, Percent_Identity=36.8243243243243, Blast_Score=189, Evalue=2e-49,
Organism=Escherichia coli, GI145693193, Length=290, Percent_Identity=35.5172413793103, Blast_Score=174, Evalue=7e-45,
Organism=Escherichia coli, GI1787128, Length=286, Percent_Identity=31.8181818181818, Blast_Score=156, Evalue=1e-39,
Organism=Escherichia coli, GI1789639, Length=292, Percent_Identity=33.9041095890411, Blast_Score=153, Evalue=1e-38,
Organism=Escherichia coli, GI1787589, Length=290, Percent_Identity=31.3793103448276, Blast_Score=138, Evalue=4e-34,
Organism=Escherichia coli, GI87081978, Length=301, Percent_Identity=31.5614617940199, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI1789440, Length=280, Percent_Identity=28.9285714285714, Blast_Score=101, Evalue=5e-23,
Organism=Escherichia coli, GI1788706, Length=300, Percent_Identity=25.3333333333333, Blast_Score=85, Evalue=8e-18,
Organism=Escherichia coli, GI1789173, Length=296, Percent_Identity=26.0135135135135, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1786448, Length=290, Percent_Identity=25.8620689655172, Blast_Score=78, Evalue=8e-16,
Organism=Escherichia coli, GI1788481, Length=290, Percent_Identity=27.5862068965517, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI157672245, Length=137, Percent_Identity=31.3868613138686, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1788748, Length=252, Percent_Identity=30.5555555555556, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1787879, Length=293, Percent_Identity=26.962457337884, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1789492, Length=254, Percent_Identity=29.9212598425197, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI1790783, Length=275, Percent_Identity=23.6363636363636, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI87082132, Length=263, Percent_Identity=26.615969581749, Blast_Score=61, Evalue=9e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34256; Mature: 34256

Theoretical pI: Translated: 9.29; Mature: 9.29

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRLSGLLAFARTAELGSFIAAGRALGISASAVGKSVARLEQELGVRLLQRSTRRVGLTE
CCHHHHHHHHHHHHHHHHHHHHCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
EGRLFNERVRRILDDIDDAEAMLSRTRETPHGRLRVSTPIVTYHLLLPVLSEFMSRYPEI
CCHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHHHHHHHHHCCCE
ELDIDFNDRIVDVIEEGIDVAIRSGELPDSRLVSRPVGPFRMLLCAAPSYLERHGTPGEP
EEEECCCHHHHHHHHHCHHEEEECCCCCCHHHHHCCCCHHHHHHHHCHHHHHHCCCCCCH
ADLIRHFGINFRFLNSGRLLEWPFITGSAEPQIRSKLTCNNMEALKGATIAGLGIACMPD
HHHHHHCCCCEEEECCCCEEEECEECCCCCCHHHHHCCCCCHHHHCCCHHHCCHHHHHHH
FLVREALLDGRLRTVLDDHIDGRGQFRMLWPSNRHLSPKVRVFVDFLPERLAAAPNTAAV
HHHHHHHHCCHHHHHHHHCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCHHHH
KSGHRKR
CCCCCCC
>Mature Secondary Structure
MDRLSGLLAFARTAELGSFIAAGRALGISASAVGKSVARLEQELGVRLLQRSTRRVGLTE
CCHHHHHHHHHHHHHHHHHHHHCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
EGRLFNERVRRILDDIDDAEAMLSRTRETPHGRLRVSTPIVTYHLLLPVLSEFMSRYPEI
CCHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHHHHHHHHHCCCE
ELDIDFNDRIVDVIEEGIDVAIRSGELPDSRLVSRPVGPFRMLLCAAPSYLERHGTPGEP
EEEECCCHHHHHHHHHCHHEEEECCCCCCHHHHHCCCCHHHHHHHHCHHHHHHCCCCCCH
ADLIRHFGINFRFLNSGRLLEWPFITGSAEPQIRSKLTCNNMEALKGATIAGLGIACMPD
HHHHHHCCCCEEEECCCCEEEECEECCCCCCHHHHHCCCCCHHHHCCCHHHCCHHHHHHH
FLVREALLDGRLRTVLDDHIDGRGQFRMLWPSNRHLSPKVRVFVDFLPERLAAAPNTAAV
HHHHHHHHCCHHHHHHHHCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCHHHH
KSGHRKR
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]