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The map label for this gene is cspA [H]

Identifier: 13472374

GI number: 13472374

Start: 2141071

End: 2141277

Strand: Direct

Name: cspA [H]

Synonym: mlr2648

Alternate gene names: 13472374

Gene position: 2141071-2141277 (Clockwise)

Preceding gene: 13472371

Following gene: 13472375

Centisome position: 30.43

GC content: 60.39

Gene sequence:

>207_bases
ATGACCACGGGAATCGTGAAATTCTACAACGGCCAGAAGGGTTTTGGCTTCATTCAACCAGCCGATGGCGGCAAGGACGT
TTTCGTCCATGTCAGCGCGCTGGAGCGCGCCGGCTTTCCAGGCCTGGCCGAAGGCCAGAAGCTGCAGTTCGACCTGGAGC
GTGACGGCAAGGGCCGCGAGTCCGCCGCCAATCTGCAACTGATCTGA

Upstream 100 bases:

>100_bases
CATCTCGCGGCGTTTCTCGACCCGCCAATCTCATTCCAAATCGTCGATGACGCACGGCACATTTGCCCTGCGACGATTTT
TCAATCCGCGAAAGACAGAT

Downstream 100 bases:

>100_bases
TCCGGCCGAATTCGATGAACGCTGACCACGGATGTACTGGCAGCTCTCGAAAGCGGCTTATTTCCAGCGATTGCCGGAAA
TAGAAAAGCGGGGCTCGTCC

Product: cold shock protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 68; Mature: 67

Protein sequence:

>68_residues
MTTGIVKFYNGQKGFGFIQPADGGKDVFVHVSALERAGFPGLAEGQKLQFDLERDGKGRESAANLQLI

Sequences:

>Translated_68_residues
MTTGIVKFYNGQKGFGFIQPADGGKDVFVHVSALERAGFPGLAEGQKLQFDLERDGKGRESAANLQLI
>Mature_67_residues
TTGIVKFYNGQKGFGFIQPADGGKDVFVHVSALERAGFPGLAEGQKLQFDLERDGKGRESAANLQLI

Specific function: Binds To And Stimulates The Transcription Of The CCAAT- Containing, Cold-Shock-Inducible Promoters Of The H-Ns And Gyra Proteins. Binds Also To The Inverted Repeat 5'-ATTGG-3'. [C]

COG id: COG1278

COG function: function code K; Cold shock proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 CSD (cold-shock) domain [H]

Homologues:

Organism=Escherichia coli, GI1789979, Length=56, Percent_Identity=58.9285714285714, Blast_Score=72, Evalue=9e-15,
Organism=Escherichia coli, GI1786841, Length=62, Percent_Identity=56.4516129032258, Blast_Score=71, Evalue=2e-14,
Organism=Escherichia coli, GI1787839, Length=65, Percent_Identity=52.3076923076923, Blast_Score=71, Evalue=2e-14,
Organism=Escherichia coli, GI1788126, Length=65, Percent_Identity=53.8461538461538, Blast_Score=69, Evalue=5e-14,
Organism=Escherichia coli, GI2367114, Length=63, Percent_Identity=50.7936507936508, Blast_Score=67, Evalue=2e-13,
Organism=Escherichia coli, GI1787834, Length=56, Percent_Identity=53.5714285714286, Blast_Score=66, Evalue=3e-13,
Organism=Escherichia coli, GI1787107, Length=62, Percent_Identity=43.5483870967742, Blast_Score=60, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019844
- InterPro:   IPR012156
- InterPro:   IPR011129
- InterPro:   IPR002059
- InterPro:   IPR012340
- InterPro:   IPR016027 [H]

Pfam domain/function: PF00313 CSD [H]

EC number: NA

Molecular weight: Translated: 7327; Mature: 7196

Theoretical pI: Translated: 7.54; Mature: 7.54

Prosite motif: PS00352 COLD_SHOCK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTGIVKFYNGQKGFGFIQPADGGKDVFVHVSALERAGFPGLAEGQKLQFDLERDGKGRE
CCCCEEEEECCCCCCEEEECCCCCCEEEEEEEECCCCCCCCCCCCCEEEEEECCCCCCCC
SAANLQLI
CCCEEEEC
>Mature Secondary Structure 
TTGIVKFYNGQKGFGFIQPADGGKDVFVHVSALERAGFPGLAEGQKLQFDLERDGKGRE
CCCEEEEECCCCCCEEEECCCCCCEEEEEEEECCCCCCCCCCCCCEEEEEECCCCCCCC
SAANLQLI
CCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10618253; 11481430 [H]