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The map label for this gene is aprE [H]

Identifier: 13472323

GI number: 13472323

Start: 2087003

End: 2088325

Strand: Reverse

Name: aprE [H]

Synonym: mll2582

Alternate gene names: 13472323

Gene position: 2088325-2087003 (Counterclockwise)

Preceding gene: 13472324

Following gene: 13472320

Centisome position: 29.68

GC content: 63.72

Gene sequence:

>1323_bases
ATGGCGGCGCAGAGCCTCACCTGGGACGAGGGCAACCCCCGTACCAACATAAGGCGCGTGGCATTCGCCGGATACGCGGC
AACGGCGCTGTTGGTGGGTTGCTTTGGCTATTGGGCTGTCAGCGCGCCCTTGTCTGGAGCGGTGATCACGCAAGGGACGA
TCTCGGCGACCGGCGGAAACATCCTGATTCAGCATCCCGAGGGCGGCATCATCGAGGCGTTGCTGGTCCATGACGGCGAT
CGCGTGCAACAGGCCCAGGATCTGATCGTGCTGGATCCGACAGCCGCGCAGGCCGAGCTCAATCGGCTGACGAGGCAGTC
GATCGCGCTCAGGGCGGCTGCAGCGCGGCTGGAGGCGGAACGCGACGGGTTGGACAGGCTCGCGCCAATCACCAAGCCGG
CGCCAGCATCGCTCCAAGCCGATTTTGAAGCCCTGATTCGAGAACAGCAAAAGGAATTCGATGCCAGACTCGCCCGGTTC
CGATCGGAACAATCGATCCTCGCCCAACGCGTAGCCATGCATCGGCAGTCCGTCGTGGGGCTGCAGTCCCAGAAAGAGGC
CGTTCAGCAGCAGGCCGAAATCGTGAAGAAGGAGCTCGGCATCAAAACCGGCCTGCTGGACAAGGGCCTCACCAATCGTA
CCGAATACTCGCAGCTTTTGCGCAGCGAGGCCGATCTCGTCGGGCAGGCCGGGGCGCTGGAAGCCAACCTGGCGGCGGCC
AACACCCAGATCGTCGAAGCCCAGGAGCAGATCGAGCGCCTGACCACGCAACGCGTGGAGGAGGCGCTGACGAAGCTGGA
CGAGGTTCGTTCCAACCTGGCCGACGTCGAGGAACAGATCAGGGCGGCCGAGGCGGTGCTGCGGCGCACGACGATCAAGG
CACCGGCCGCGGGCATCGTGGTGTCCTCGACCTATAATACCAAGGGCAGCGTGATTGCGCGCGGCGAGAAGATCATGGAA
ATCCTGCCCACGGCACCGGGTCTGATTGTCGATGCAAGGCTGCGGCCGAAGGACGTCGATCAGGTCCGTGTCGGCCAACC
GGCGAAACTGCGATTGTCCGCCTTGAACATGCGGCTCACCCCCGAGGTTTCAGCCACCGTGGCACAAATTTCCGCGGACC
GGCTCATCGACGAGGCTACCCATGAGCCCTATTTCCGCGTCAAACTCAGGATTGCCGCCGACCTGCCGCCCGGCGTGAAG
CCCGGGCAGCTCTATCCCGGAACGCCGGTCGAGGCGTTCATCAATACTGGCGACCGGACTTTCTTCGAGTATCTGGTACG
GCCAATGCTCGATTCCTTCGCGCGCGCGTTCACGGAGCGGTAG

Upstream 100 bases:

>100_bases
GGTCGTTGGCAAGGGCCTTCCCGCGCAGCCGAATACGGTGGTGACAGGATCCTTCGCCACGACGATCCGCGCGCATAACA
CCCGTTTTGGATCGTAGATG

Downstream 100 bases:

>100_bases
CTGCCACGCAATCCACCGGCCAACCGCCAATGACCGCCAAGGCCTGAAGCTGACATTCAAACAATCAGCGCACCGCCTCG
CGGTGGGTGCCGGGCAAGCG

Product: metalloprotease transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 440; Mature: 439

Protein sequence:

>440_residues
MAAQSLTWDEGNPRTNIRRVAFAGYAATALLVGCFGYWAVSAPLSGAVITQGTISATGGNILIQHPEGGIIEALLVHDGD
RVQQAQDLIVLDPTAAQAELNRLTRQSIALRAAAARLEAERDGLDRLAPITKPAPASLQADFEALIREQQKEFDARLARF
RSEQSILAQRVAMHRQSVVGLQSQKEAVQQQAEIVKKELGIKTGLLDKGLTNRTEYSQLLRSEADLVGQAGALEANLAAA
NTQIVEAQEQIERLTTQRVEEALTKLDEVRSNLADVEEQIRAAEAVLRRTTIKAPAAGIVVSSTYNTKGSVIARGEKIME
ILPTAPGLIVDARLRPKDVDQVRVGQPAKLRLSALNMRLTPEVSATVAQISADRLIDEATHEPYFRVKLRIAADLPPGVK
PGQLYPGTPVEAFINTGDRTFFEYLVRPMLDSFARAFTER

Sequences:

>Translated_440_residues
MAAQSLTWDEGNPRTNIRRVAFAGYAATALLVGCFGYWAVSAPLSGAVITQGTISATGGNILIQHPEGGIIEALLVHDGD
RVQQAQDLIVLDPTAAQAELNRLTRQSIALRAAAARLEAERDGLDRLAPITKPAPASLQADFEALIREQQKEFDARLARF
RSEQSILAQRVAMHRQSVVGLQSQKEAVQQQAEIVKKELGIKTGLLDKGLTNRTEYSQLLRSEADLVGQAGALEANLAAA
NTQIVEAQEQIERLTTQRVEEALTKLDEVRSNLADVEEQIRAAEAVLRRTTIKAPAAGIVVSSTYNTKGSVIARGEKIME
ILPTAPGLIVDARLRPKDVDQVRVGQPAKLRLSALNMRLTPEVSATVAQISADRLIDEATHEPYFRVKLRIAADLPPGVK
PGQLYPGTPVEAFINTGDRTFFEYLVRPMLDSFARAFTER
>Mature_439_residues
AAQSLTWDEGNPRTNIRRVAFAGYAATALLVGCFGYWAVSAPLSGAVITQGTISATGGNILIQHPEGGIIEALLVHDGDR
VQQAQDLIVLDPTAAQAELNRLTRQSIALRAAAARLEAERDGLDRLAPITKPAPASLQADFEALIREQQKEFDARLARFR
SEQSILAQRVAMHRQSVVGLQSQKEAVQQQAEIVKKELGIKTGLLDKGLTNRTEYSQLLRSEADLVGQAGALEANLAAAN
TQIVEAQEQIERLTTQRVEEALTKLDEVRSNLADVEEQIRAAEAVLRRTTIKAPAAGIVVSSTYNTKGSVIARGEKIMEI
LPTAPGLIVDARLRPKDVDQVRVGQPAKLRLSALNMRLTPEVSATVAQISADRLIDEATHEPYFRVKLRIAADLPPGVKP
GQLYPGTPVEAFINTGDRTFFEYLVRPMLDSFARAFTER

Specific function: Involved in the secretion of alkaline protease [H]

COG id: COG0845

COG function: function code M; Membrane-fusion protein

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003997
- InterPro:   IPR006143
- InterPro:   IPR006144
- InterPro:   IPR010129 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 47918; Mature: 47787

Theoretical pI: Translated: 6.56; Mature: 6.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAQSLTWDEGNPRTNIRRVAFAGYAATALLVGCFGYWAVSAPLSGAVITQGTISATGGN
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCEEEECCCE
ILIQHPEGGIIEALLVHDGDRVQQAQDLIVLDPTAAQAELNRLTRQSIALRAAAARLEAE
EEEECCCCCEEEEEEECCCHHHHHHCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHH
RDGLDRLAPITKPAPASLQADFEALIREQQKEFDARLARFRSEQSILAQRVAMHRQSVVG
HCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
LQSQKEAVQQQAEIVKKELGIKTGLLDKGLTNRTEYSQLLRSEADLVGQAGALEANLAAA
CHHHHHHHHHHHHHHHHHHCCHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHC
NTQIVEAQEQIERLTTQRVEEALTKLDEVRSNLADVEEQIRAAEAVLRRTTIKAPAAGIV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEE
VSSTYNTKGSVIARGEKIMEILPTAPGLIVDARLRPKDVDQVRVGQPAKLRLSALNMRLT
EEECCCCCCCEEECCHHHHHHHCCCCCEEEECCCCCCCCCHHCCCCCCCEEHEECCEEEC
PEVSATVAQISADRLIDEATHEPYFRVKLRIAADLPPGVKPGQLYPGTPVEAFINTGDRT
CCHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCCCCCCCCCCCCCCHHHHHCCCCHH
FFEYLVRPMLDSFARAFTER
HHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AAQSLTWDEGNPRTNIRRVAFAGYAATALLVGCFGYWAVSAPLSGAVITQGTISATGGN
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCEEEECCCE
ILIQHPEGGIIEALLVHDGDRVQQAQDLIVLDPTAAQAELNRLTRQSIALRAAAARLEAE
EEEECCCCCEEEEEEECCCHHHHHHCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHH
RDGLDRLAPITKPAPASLQADFEALIREQQKEFDARLARFRSEQSILAQRVAMHRQSVVG
HCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
LQSQKEAVQQQAEIVKKELGIKTGLLDKGLTNRTEYSQLLRSEADLVGQAGALEANLAAA
CHHHHHHHHHHHHHHHHHHCCHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHC
NTQIVEAQEQIERLTTQRVEEALTKLDEVRSNLADVEEQIRAAEAVLRRTTIKAPAAGIV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEE
VSSTYNTKGSVIARGEKIMEILPTAPGLIVDARLRPKDVDQVRVGQPAKLRLSALNMRLT
EEECCCCCCCEEECCHHHHHHHCCCCCEEEECCCCCCCCCHHCCCCCCCEEHEECCEEEC
PEVSATVAQISADRLIDEATHEPYFRVKLRIAADLPPGVKPGQLYPGTPVEAFINTGDRT
CCHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCCCCCCCCCCCCCCHHHHHCCCCHH
FFEYLVRPMLDSFARAFTER
HHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1427098; 10984043 [H]