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The map label for this gene is catB4 [H]

Identifier: 13472117

GI number: 13472117

Start: 1863941

End: 1864531

Strand: Reverse

Name: catB4 [H]

Synonym: mll2311

Alternate gene names: 13472117

Gene position: 1864531-1863941 (Counterclockwise)

Preceding gene: 13472118

Following gene: 13472115

Centisome position: 26.5

GC content: 56.01

Gene sequence:

>591_bases
ATGGGATTTGCAAGAAAACTTCGAACCATGCTCGGTCTTAGACGAGCGCCAAAGCCGGAAAAGATACCGCTGCACGCATC
GATCGGGCGAAGAACGCTCTTTTACACGAAGCCCAGCAATATCTATGGCTGTGACGAGACCTCGCCGCTTGAGATAGGAG
CGTTCTGCTCCATAGCGGAGGAGACGCTGTTCCTTTGCCGCGCCAATCATCCGACGCACTTCGTCTCGACTTTTCCATTT
GAAGTTCACATGACAAATTCGATCGCGGCCTTTGATGACCTGGTGGTCAACGGGCCGACAAAAATCGGCAACGATGTCTG
GATTGGACGACGCGCAATCATCCTGCCGGGAATAACCATTGGAGATGGTGCCGTTGTCGGAGCCGGCTCGGTCGTCACGA
AGGACGTCGCACCCTACGCGGTCGTCGCGGGAAATCCCGCCAGGTTCATCCGGAACAGGTTTACGGATGACCAGATCGCG
AGTTTGCTGGCGATTCGCTGGTGGGAGTGGAGCGACGAGAGGATCAAGGCCGAACTGCCGACCTTCCTTGGATCGATTGA
TGCCTTCATCGCCGCCAACCGTGCATCATAG

Upstream 100 bases:

>100_bases
GGTGTTGCGAAAGCCGACCTGATGGGTATGGAAATGGACGCCTCCGCACGCAAGCCCTTTCCGTGACGGCCGGTCAAGAC
CAACCATGGCTTAGAAACAA

Downstream 100 bases:

>100_bases
CCCAGCGGTGTCAATACAGAACTCATGGAACTGCTTTCCGCTTGTGCTGAACGGCACCATGCCCTCACCCGATCCCGCCG
GTAACCACATAGGCGCCGGC

Product: chloramphenicol acetyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 196; Mature: 195

Protein sequence:

>196_residues
MGFARKLRTMLGLRRAPKPEKIPLHASIGRRTLFYTKPSNIYGCDETSPLEIGAFCSIAEETLFLCRANHPTHFVSTFPF
EVHMTNSIAAFDDLVVNGPTKIGNDVWIGRRAIILPGITIGDGAVVGAGSVVTKDVAPYAVVAGNPARFIRNRFTDDQIA
SLLAIRWWEWSDERIKAELPTFLGSIDAFIAANRAS

Sequences:

>Translated_196_residues
MGFARKLRTMLGLRRAPKPEKIPLHASIGRRTLFYTKPSNIYGCDETSPLEIGAFCSIAEETLFLCRANHPTHFVSTFPF
EVHMTNSIAAFDDLVVNGPTKIGNDVWIGRRAIILPGITIGDGAVVGAGSVVTKDVAPYAVVAGNPARFIRNRFTDDQIA
SLLAIRWWEWSDERIKAELPTFLGSIDAFIAANRAS
>Mature_195_residues
GFARKLRTMLGLRRAPKPEKIPLHASIGRRTLFYTKPSNIYGCDETSPLEIGAFCSIAEETLFLCRANHPTHFVSTFPFE
VHMTNSIAAFDDLVVNGPTKIGNDVWIGRRAIILPGITIGDGAVVGAGSVVTKDVAPYAVVAGNPARFIRNRFTDDQIAS
LLAIRWWEWSDERIKAELPTFLGSIDAFIAANRAS

Specific function: This enzyme is an effector of chloramphenicol resistance in bacteria [H]

COG id: COG0110

COG function: function code R; Acetyltransferase (isoleucine patch superfamily)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family [H]

Homologues:

Organism=Escherichia coli, GI1786664, Length=106, Percent_Identity=41.5094339622642, Blast_Score=74, Evalue=7e-15,
Organism=Escherichia coli, GI1786537, Length=53, Percent_Identity=60.377358490566, Blast_Score=71, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018357
- InterPro:   IPR011004 [H]

Pfam domain/function: NA

EC number: =2.3.1.28 [H]

Molecular weight: Translated: 21532; Mature: 21401

Theoretical pI: Translated: 8.87; Mature: 8.87

Prosite motif: PS00101 HEXAPEP_TRANSFERASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGFARKLRTMLGLRRAPKPEKIPLHASIGRRTLFYTKPSNIYGCDETSPLEIGAFCSIAE
CCHHHHHHHHHHHHCCCCCCCCEEEECCCCEEEEEECCCCEECCCCCCCEEEHHHHHHHH
ETLFLCRANHPTHFVSTFPFEVHMTNSIAAFDDLVVNGPTKIGNDVWIGRRAIILPGITI
HEEEEEECCCCCEEEEECCEEEEECCCHHHHHHEEECCCCCCCCEEEECCEEEEECCEEE
GDGAVVGAGSVVTKDVAPYAVVAGNPARFIRNRFTDDQIASLLAIRWWEWSDERIKAELP
CCCCEEECCCEEECCCCCEEEEECCHHHHHHHCCCHHHHHHHHHHHEECCCCCHHHHHHH
TFLGSIDAFIAANRAS
HHHHHHHHHEEECCCC
>Mature Secondary Structure 
GFARKLRTMLGLRRAPKPEKIPLHASIGRRTLFYTKPSNIYGCDETSPLEIGAFCSIAE
CHHHHHHHHHHHHCCCCCCCCEEEECCCCEEEEEECCCCEECCCCCCCEEEHHHHHHHH
ETLFLCRANHPTHFVSTFPFEVHMTNSIAAFDDLVVNGPTKIGNDVWIGRRAIILPGITI
HEEEEEECCCCCEEEEECCEEEEECCCHHHHHHEEECCCCCCCCEEEECCEEEEECCEEE
GDGAVVGAGSVVTKDVAPYAVVAGNPARFIRNRFTDDQIASLLAIRWWEWSDERIKAELP
CCCCEEECCCEEECCCCCEEEEECCHHHHHHHCCCHHHHHHHHHHHEECCCCCHHHHHHH
TFLGSIDAFIAANRAS
HHHHHHHHHEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7793874 [H]