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The map label for this gene is 13472036

Identifier: 13472036

GI number: 13472036

Start: 1780205

End: 1781365

Strand: Direct

Name: 13472036

Synonym: mlr2199

Alternate gene names: NA

Gene position: 1780205-1781365 (Clockwise)

Preceding gene: 13472035

Following gene: 13472037

Centisome position: 25.3

GC content: 65.89

Gene sequence:

>1161_bases
ATGAGGATCGCGGTTCTCGGCGGCCTCGGCCTGCAAGGCCGGGCGGCCATCGCCGATCTCGTCGCCAGCGGTGTCGATGA
GGTGATCTGCGTCGATACCGCGCCGGATGGCGCGGCCCGGCTGGCTGATCTGACCGACCTTTCCCGCGTGCGCTTCGTCG
TGCCAGAAGGCGCGATCGGACCGGCGCTTGCCGATGTGCTGGCTGACGCCGACTCCGTCATCGATTTGCTGCCGCAGCCG
CTGATGCGCGAGGCGGTGCAAGCCGCGATCGCAACCCGCACGCCGCTGGTCACCACCAATTACGGCAAGGCCATCGCCGA
CCTGGCGCCGGAAGCCGAACGGGCCGGCGTTTCGGTCATGACCGAATGCGGGCTCGACCCCGGCATCGACCTTGTGCTCT
ACGCCCGCGCCGCAAAACAGTTCGATGCGATCACATCGATCGATTCCTATTGCGGCGGCATCCCCGAGCCGAAGGCGATG
GCCAAGCCGCTTTGCTACAAGGTGAGCTGGAACTTCGACATGGTCCTGGTCAGCCAGAACCGCGACAGCGTGATGATCGA
GGACGGCAAGCGCGTCGAAGTACCCGCCGCCCGCCAGCATGACAGCCCTTTCATCCATGAGATCGAAGTCGCCGGCCTCG
GCCGGCTGGAAGCCTTCCCCAATGGCGATGCGCTGCATTATGTCGAGATGCTTCCCGCCGCAAAGGGGCTGCGCCGCTCC
GGCCGCTACACGTTGCGCTGGCCGGGATGGTCGGCCTTCTGGGCGCCGTTGAAGGAGCTTGGTTTTCTCTCCGAGGACAA
GGTGCCCGGCACCTCCAGCAGCCCGCGCGAATTCCTCGGCCGGCTGCTCGGCCCGCAACTGCAATACGGCCCCGGCGAGA
AGGACCTTTGCGTGATGCGCAATGTCTTTTCCGGCCTCGAAGGCGGCCGCGCCAAGACCGTGACATCCGATCTGATCATC
GAGCGCGACCTCGCGTCGGGCCTGTTCGGCATGAGCCTCGGCGTCGGCTATCCCGCCAGCATCGTGGCGCAGATGCTCGC
GCGGCGCGAGATCATCACGCCGGGCCTTTTGAACCCGCTGCTCGACGTGCCCGACGAACCCTTCTTCGACGAATTGGCCA
AACGCGGCATCAAAATTGCCGAGACGGTGGCCTGGGACTGA

Upstream 100 bases:

>100_bases
GCGAGGTCGTGCGCAGCGAGACCTTCGTCGTCATGGCGTCCTGCAACAAATGGGTCAGCCTGCCAGAAGGCTGCTGGTCG
GACGACCGCAAGGAGCCGGC

Downstream 100 bases:

>100_bases
GGATTTCGAACGGTGGCCGCCGCCGGCAACGGCGCTGCCGCTCAAAAAAGCACCCCGAAGGGTGAAACAACAACGTGGAA
CAATAAAACAAGGAGGAATG

Product: lysine oxoglutarate reductase/saccharopine dehydrogenase

Products: NA

Alternate protein names: L-Lysine Dehydrogenase; Saccharopine Reductase; Oxidoreductase; Saccharopine Dehydrogenase-Like Protein; Saccharopine Dehydrogenase Family Protein; Lysine Oxoglutarate Reductase/Saccharopine Dehydrogenase

Number of amino acids: Translated: 386; Mature: 386

Protein sequence:

>386_residues
MRIAVLGGLGLQGRAAIADLVASGVDEVICVDTAPDGAARLADLTDLSRVRFVVPEGAIGPALADVLADADSVIDLLPQP
LMREAVQAAIATRTPLVTTNYGKAIADLAPEAERAGVSVMTECGLDPGIDLVLYARAAKQFDAITSIDSYCGGIPEPKAM
AKPLCYKVSWNFDMVLVSQNRDSVMIEDGKRVEVPAARQHDSPFIHEIEVAGLGRLEAFPNGDALHYVEMLPAAKGLRRS
GRYTLRWPGWSAFWAPLKELGFLSEDKVPGTSSSPREFLGRLLGPQLQYGPGEKDLCVMRNVFSGLEGGRAKTVTSDLII
ERDLASGLFGMSLGVGYPASIVAQMLARREIITPGLLNPLLDVPDEPFFDELAKRGIKIAETVAWD

Sequences:

>Translated_386_residues
MRIAVLGGLGLQGRAAIADLVASGVDEVICVDTAPDGAARLADLTDLSRVRFVVPEGAIGPALADVLADADSVIDLLPQP
LMREAVQAAIATRTPLVTTNYGKAIADLAPEAERAGVSVMTECGLDPGIDLVLYARAAKQFDAITSIDSYCGGIPEPKAM
AKPLCYKVSWNFDMVLVSQNRDSVMIEDGKRVEVPAARQHDSPFIHEIEVAGLGRLEAFPNGDALHYVEMLPAAKGLRRS
GRYTLRWPGWSAFWAPLKELGFLSEDKVPGTSSSPREFLGRLLGPQLQYGPGEKDLCVMRNVFSGLEGGRAKTVTSDLII
ERDLASGLFGMSLGVGYPASIVAQMLARREIITPGLLNPLLDVPDEPFFDELAKRGIKIAETVAWD
>Mature_386_residues
MRIAVLGGLGLQGRAAIADLVASGVDEVICVDTAPDGAARLADLTDLSRVRFVVPEGAIGPALADVLADADSVIDLLPQP
LMREAVQAAIATRTPLVTTNYGKAIADLAPEAERAGVSVMTECGLDPGIDLVLYARAAKQFDAITSIDSYCGGIPEPKAM
AKPLCYKVSWNFDMVLVSQNRDSVMIEDGKRVEVPAARQHDSPFIHEIEVAGLGRLEAFPNGDALHYVEMLPAAKGLRRS
GRYTLRWPGWSAFWAPLKELGFLSEDKVPGTSSSPREFLGRLLGPQLQYGPGEKDLCVMRNVFSGLEGGRAKTVTSDLII
ERDLASGLFGMSLGVGYPASIVAQMLARREIITPGLLNPLLDVPDEPFFDELAKRGIKIAETVAWD

Specific function: Unknown

COG id: COG1748

COG function: function code E; Saccharopine dehydrogenase and related proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI13027640, Length=384, Percent_Identity=29.9479166666667, Blast_Score=112, Evalue=6e-25,
Organism=Caenorhabditis elegans, GI17541738, Length=450, Percent_Identity=25.5555555555556, Blast_Score=100, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6324378, Length=215, Percent_Identity=34.4186046511628, Blast_Score=102, Evalue=1e-22,
Organism=Drosophila melanogaster, GI23397395, Length=207, Percent_Identity=30.9178743961353, Blast_Score=91, Evalue=9e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 41382; Mature: 41382

Theoretical pI: Translated: 4.61; Mature: 4.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIAVLGGLGLQGRAAIADLVASGVDEVICVDTAPDGAARLADLTDLSRVRFVVPEGAIG
CEEEEEECCCCCCHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHEEEECCCCCCH
PALADVLADADSVIDLLPQPLMREAVQAAIATRTPLVTTNYGKAIADLAPEAERAGVSVM
HHHHHHHHCHHHHHHHCCCHHHHHHHHHHHHHCCCEEECCCCHHHHHHCCCHHHCCCHHH
TECGLDPGIDLVLYARAAKQFDAITSIDSYCGGIPEPKAMAKPLCYKVSWNFDMVLVSQN
HHCCCCCCCCEEEEHHHHHHHHHHHHHHHHHCCCCCCHHHHCCEEEEEECCEEEEEEECC
RDSVMIEDGKRVEVPAARQHDSPFIHEIEVAGLGRLEAFPNGDALHYVEMLPAAKGLRRS
CCEEEEECCCEEECCCCCCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHC
GRYTLRWPGWSAFWAPLKELGFLSEDKVPGTSSSPREFLGRLLGPQLQYGPGEKDLCVMR
CCEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHH
NVFSGLEGGRAKTVTSDLIIERDLASGLFGMSLGVGYPASIVAQMLARREIITPGLLNPL
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHH
LDVPDEPFFDELAKRGIKIAETVAWD
HCCCCCCHHHHHHHCCCEEHHHHCCC
>Mature Secondary Structure
MRIAVLGGLGLQGRAAIADLVASGVDEVICVDTAPDGAARLADLTDLSRVRFVVPEGAIG
CEEEEEECCCCCCHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHEEEECCCCCCH
PALADVLADADSVIDLLPQPLMREAVQAAIATRTPLVTTNYGKAIADLAPEAERAGVSVM
HHHHHHHHCHHHHHHHCCCHHHHHHHHHHHHHCCCEEECCCCHHHHHHCCCHHHCCCHHH
TECGLDPGIDLVLYARAAKQFDAITSIDSYCGGIPEPKAMAKPLCYKVSWNFDMVLVSQN
HHCCCCCCCCEEEEHHHHHHHHHHHHHHHHHCCCCCCHHHHCCEEEEEECCEEEEEEECC
RDSVMIEDGKRVEVPAARQHDSPFIHEIEVAGLGRLEAFPNGDALHYVEMLPAAKGLRRS
CCEEEEECCCEEECCCCCCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHC
GRYTLRWPGWSAFWAPLKELGFLSEDKVPGTSSSPREFLGRLLGPQLQYGPGEKDLCVMR
CCEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHH
NVFSGLEGGRAKTVTSDLIIERDLASGLFGMSLGVGYPASIVAQMLARREIITPGLLNPL
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHH
LDVPDEPFFDELAKRGIKIAETVAWD
HCCCCCCHHHHHHHCCCEEHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA