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The map label for this gene is katE [H]

Identifier: 13471962

GI number: 13471962

Start: 1719496

End: 1721604

Strand: Direct

Name: katE [H]

Synonym: mlr2101

Alternate gene names: 13471962

Gene position: 1719496-1721604 (Clockwise)

Preceding gene: 13471961

Following gene: 13471965

Centisome position: 24.44

GC content: 63.63

Gene sequence:

>2109_bases
ATGGCGAAGCAAGCATCCAAATTGGCCGGAACGGCCGCGACCATCCACGATCAGAAACTGCAGCGCGGCGAAGGCGGCGA
ACTGCACCAGACCGCGTCCGGTTCGACAGCCGTACTGACCACCGCACAGGGCGGCCCTGTCTCGGACGACCAGAACTCGC
TGAGGATCGGTGCGCGTGGGCCAACCGTGCTCGAGGACTTCCACTTCCGCGAAAAGATCTTCCATTTCGATCACGAGCGC
ATTCCCGAGCGCGTCGTCCATGCGCGTGGCTATGGCGCGCACGGCTATTTCGAAACCTATGAATCGCTGGCCAAATACAC
CCGCGCCGACATCTTCCAGCGCGCCGGCGAAAAGACGCCGGCTTTCGTGCGCTTCTCCACCGTTGCCGGCAATAAGGGCT
CCGCCGATCTTGCCCGCGACGTCCGTGGCTTCGCCGTAAAACTCTACACGCAGGAAGGCAATTGGGACATTGTCGGCAAC
AACATGCCGGTGTTCTTCATCCAGGATGCGATCAAGTTTCCCGACCTGATCCATGCCGCGAAGGCCGAGCCCAACAGCGA
TTTCCCGCAGGCACAGACCGCGCACGACAATTTCTGGGATTTCATCTCGCTCACGCCGGAAAGCATGCACATGATCATGT
GGGCGATGTCCGACCGCGCCATCCCGCGCTCGCTGCGCTTCATGGAAGGGTTCGGCGTCCACACTTTCCGGCTGCTCAAC
GCGAAGGATGAATCGACCTTCGTCAAATTCCTCTGGAAGCCGAAGCTCGGCCTCCAGTCGGTCGCCTGGAACGAGGCGGT
CAAGATCAACGGCGCCGACCCCGACTTCCATCGCCGCGACCTCTGGGACGCGATCCACGCCGGGAATTTCCCCGAATGGG
AACTGCAGCTGCAGCTCTTCGACCAGGCCTTCGCCGACAGCTTCGACTTCGACATCCTCGATCCGACCAAACTCATCCCC
GAGGAGGTGCTGCCGCCGATCGCGGTCGGCCGACTGGTCCTCGATCGCATGCCCGACAATTTCTTCGCCGAGACCGAGCA
GGTGGCGTTCATGACGCAGAACGTGCCGCCCGGCGTCGACTTCTCCAACGACCCGCTGCTGCAGGGCCGCAATTTTTCCT
ATCTCGACACGCAGATCAAACGGCTGGGCAGCACCAACTTCACCCACCTCCCGATCAACGCGCCGAAATGCCCCTTCCAC
ACTTTCCAGCAGGACGGGCACATGGCGATGCGCAACCCGGTGGGCCGCGCCAACTACCAGCCCAATTCATGGGATGAAGG
CCCGCGCGAATCTCCGCAAAAGGGCTTCCGATCCTTTGCCGAAGCCGAAGCCGGACCGAAGGCCCGCCTGCGGGCGGAAA
GCTTTGCCGATCACTACAGCCAGGCACGCCAATTCTACATCAGCCAGCACCCCGTGGAACAAGGCCACATCGCCTCGGCG
CTGACCTTCGAACTGAGCAAGGTGCACACCCCGGTCATCCGCGAGCGCATCGTATCCCACCTCCTCAATATCGATGATGC
GTTGGCTCGCAAGGTGGCGGATGCGCTGGGCCTGAAGGCGATGCCGAAGCCCGCCGATGCGGGGGCGCCGACGCGCACCG
ACCTTCCCGCGTCCGACGCGCTCAGCATCCTCAAGAACGGCCCCGGCCGCTTCGAGGGACGCAAGCTCGGCATCCTGGTG
ACCGACGGCACCGACGCAGCTCTGCTCAATGCTCTGAAGCAGGCGCTGACCAAGGCCGGCGCCAAGTTCGAGATCATCGC
GCCGAAGGTCGGCGGCGCCAAGGCCAGCGACGGCAGCTGGATGGACGCGCAGCAGATGATCGCCGGCGCGCCGTCTGTTC
TCTACGACGCCATTGCGCTGCTGGCGGCAAAGCCTGCAATGGCCGGGCTGCTGAGGGAATCGACCGCCCGCGACTTCGTC
GCCGACGCCTTTGCGCACTGCAAATTCATCGGCTTCGTCGAGGCGGCGGCACCACTGCTGGACAAGGCCGGAGTTGTCGA
GGACGAGGCGGTGATCCCGCTTGCATCCGCCAAGGATGTCGCGGGCTTCATCACCAGGCTCGGCGACCTGCGCCTCTGGG
CACGCGAGCCGAAGGTGAAGCTGGGCTGA

Upstream 100 bases:

>100_bases
CTTTCTTCATTCGCGGATTTGAAATCGGCGGGGAACGCATTGCCACCCCAGAGATTGAGGAACCAGCGCAGCCCGCGCAT
TGACCCAGGGATTTTCAGTC

Downstream 100 bases:

>100_bases
ACCACGAACTGAACCTGGCTGCGCCCACGCGACCGAGGCGCGGCCAGATCCAGCCGCGTGCGCATTGAGGCATCCGTGCA
GCCAGATCAGCCAAGACCTG

Product: catalase

Products: NA

Alternate protein names: KAT2 [H]

Number of amino acids: Translated: 702; Mature: 701

Protein sequence:

>702_residues
MAKQASKLAGTAATIHDQKLQRGEGGELHQTASGSTAVLTTAQGGPVSDDQNSLRIGARGPTVLEDFHFREKIFHFDHER
IPERVVHARGYGAHGYFETYESLAKYTRADIFQRAGEKTPAFVRFSTVAGNKGSADLARDVRGFAVKLYTQEGNWDIVGN
NMPVFFIQDAIKFPDLIHAAKAEPNSDFPQAQTAHDNFWDFISLTPESMHMIMWAMSDRAIPRSLRFMEGFGVHTFRLLN
AKDESTFVKFLWKPKLGLQSVAWNEAVKINGADPDFHRRDLWDAIHAGNFPEWELQLQLFDQAFADSFDFDILDPTKLIP
EEVLPPIAVGRLVLDRMPDNFFAETEQVAFMTQNVPPGVDFSNDPLLQGRNFSYLDTQIKRLGSTNFTHLPINAPKCPFH
TFQQDGHMAMRNPVGRANYQPNSWDEGPRESPQKGFRSFAEAEAGPKARLRAESFADHYSQARQFYISQHPVEQGHIASA
LTFELSKVHTPVIRERIVSHLLNIDDALARKVADALGLKAMPKPADAGAPTRTDLPASDALSILKNGPGRFEGRKLGILV
TDGTDAALLNALKQALTKAGAKFEIIAPKVGGAKASDGSWMDAQQMIAGAPSVLYDAIALLAAKPAMAGLLRESTARDFV
ADAFAHCKFIGFVEAAAPLLDKAGVVEDEAVIPLASAKDVAGFITRLGDLRLWAREPKVKLG

Sequences:

>Translated_702_residues
MAKQASKLAGTAATIHDQKLQRGEGGELHQTASGSTAVLTTAQGGPVSDDQNSLRIGARGPTVLEDFHFREKIFHFDHER
IPERVVHARGYGAHGYFETYESLAKYTRADIFQRAGEKTPAFVRFSTVAGNKGSADLARDVRGFAVKLYTQEGNWDIVGN
NMPVFFIQDAIKFPDLIHAAKAEPNSDFPQAQTAHDNFWDFISLTPESMHMIMWAMSDRAIPRSLRFMEGFGVHTFRLLN
AKDESTFVKFLWKPKLGLQSVAWNEAVKINGADPDFHRRDLWDAIHAGNFPEWELQLQLFDQAFADSFDFDILDPTKLIP
EEVLPPIAVGRLVLDRMPDNFFAETEQVAFMTQNVPPGVDFSNDPLLQGRNFSYLDTQIKRLGSTNFTHLPINAPKCPFH
TFQQDGHMAMRNPVGRANYQPNSWDEGPRESPQKGFRSFAEAEAGPKARLRAESFADHYSQARQFYISQHPVEQGHIASA
LTFELSKVHTPVIRERIVSHLLNIDDALARKVADALGLKAMPKPADAGAPTRTDLPASDALSILKNGPGRFEGRKLGILV
TDGTDAALLNALKQALTKAGAKFEIIAPKVGGAKASDGSWMDAQQMIAGAPSVLYDAIALLAAKPAMAGLLRESTARDFV
ADAFAHCKFIGFVEAAAPLLDKAGVVEDEAVIPLASAKDVAGFITRLGDLRLWAREPKVKLG
>Mature_701_residues
AKQASKLAGTAATIHDQKLQRGEGGELHQTASGSTAVLTTAQGGPVSDDQNSLRIGARGPTVLEDFHFREKIFHFDHERI
PERVVHARGYGAHGYFETYESLAKYTRADIFQRAGEKTPAFVRFSTVAGNKGSADLARDVRGFAVKLYTQEGNWDIVGNN
MPVFFIQDAIKFPDLIHAAKAEPNSDFPQAQTAHDNFWDFISLTPESMHMIMWAMSDRAIPRSLRFMEGFGVHTFRLLNA
KDESTFVKFLWKPKLGLQSVAWNEAVKINGADPDFHRRDLWDAIHAGNFPEWELQLQLFDQAFADSFDFDILDPTKLIPE
EVLPPIAVGRLVLDRMPDNFFAETEQVAFMTQNVPPGVDFSNDPLLQGRNFSYLDTQIKRLGSTNFTHLPINAPKCPFHT
FQQDGHMAMRNPVGRANYQPNSWDEGPRESPQKGFRSFAEAEAGPKARLRAESFADHYSQARQFYISQHPVEQGHIASAL
TFELSKVHTPVIRERIVSHLLNIDDALARKVADALGLKAMPKPADAGAPTRTDLPASDALSILKNGPGRFEGRKLGILVT
DGTDAALLNALKQALTKAGAKFEIIAPKVGGAKASDGSWMDAQQMIAGAPSVLYDAIALLAAKPAMAGLLRESTARDFVA
DAFAHCKFIGFVEAAAPLLDKAGVVEDEAVIPLASAKDVAGFITRLGDLRLWAREPKVKLG

Specific function: Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide. Could protect cells in nodules which have a high potential to produce hydrogen peroxide because of the strong reducing conditions requ

COG id: COG0753

COG function: function code P; Catalase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the catalase family. HPII subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557014, Length=468, Percent_Identity=43.5897435897436, Blast_Score=382, Evalue=1e-106,
Organism=Escherichia coli, GI48994891, Length=675, Percent_Identity=49.4814814814815, Blast_Score=646, Evalue=0.0,
Organism=Caenorhabditis elegans, GI25147792, Length=479, Percent_Identity=42.1711899791232, Blast_Score=372, Evalue=1e-103,
Organism=Caenorhabditis elegans, GI25151141, Length=479, Percent_Identity=42.1711899791232, Blast_Score=372, Evalue=1e-103,
Organism=Caenorhabditis elegans, GI71998444, Length=434, Percent_Identity=43.3179723502304, Blast_Score=365, Evalue=1e-101,
Organism=Saccharomyces cerevisiae, GI6320462, Length=505, Percent_Identity=35.2475247524752, Blast_Score=295, Evalue=1e-80,
Organism=Saccharomyces cerevisiae, GI6321525, Length=521, Percent_Identity=33.2053742802303, Blast_Score=276, Evalue=1e-74,
Organism=Drosophila melanogaster, GI17981717, Length=497, Percent_Identity=39.8390342052314, Blast_Score=361, Evalue=1e-100,
Organism=Drosophila melanogaster, GI19920968, Length=488, Percent_Identity=37.5, Blast_Score=347, Evalue=2e-95,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002226
- InterPro:   IPR020835
- InterPro:   IPR010582
- InterPro:   IPR018028
- InterPro:   IPR011614 [H]

Pfam domain/function: PF00199 Catalase; PF06628 Catalase-rel [H]

EC number: =1.11.1.6 [H]

Molecular weight: Translated: 77266; Mature: 77135

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: PS00437 CATALASE_1 ; PS00438 CATALASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKQASKLAGTAATIHDQKLQRGEGGELHQTASGSTAVLTTAQGGPVSDDQNSLRIGARG
CCCCHHHHHCCHHHHHHHHHHCCCCCCEEECCCCCEEEEEECCCCCCCCCCCCEEECCCC
PTVLEDFHFREKIFHFDHERIPERVVHARGYGAHGYFETYESLAKYTRADIFQRAGEKTP
CHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCC
AFVRFSTVAGNKGSADLARDVRGFAVKLYTQEGNWDIVGNNMPVFFIQDAIKFPDLIHAA
CEEEEEEECCCCCCHHHHHHHCCEEEEEEEECCCEEEECCCCCEEEECCHHCCHHHHHHH
KAEPNSDFPQAQTAHDNFWDFISLTPESMHMIMWAMSDRAIPRSLRFMEGFGVHTFRLLN
CCCCCCCCCCCCCCCCCCHHHEEECHHHHHHHHHHHCCCCCHHHHHHHHCCCCEEEEEEC
AKDESTFVKFLWKPKLGLQSVAWNEAVKINGADPDFHRRDLWDAIHAGNFPEWELQLQLF
CCCCCCEEHEEECCCCCCHHHCCCCEEEECCCCCCHHHHHHHHHHHCCCCCCHHHHHHHH
DQAFADSFDFDILDPTKLIPEEVLPPIAVGRLVLDRMPDNFFAETEQVAFMTQNVPPGVD
HHHHHCCCCCCCCCCHHHCHHHHCCHHHHHHHHHHHCCCHHHHCCHHHEEEECCCCCCCC
FSNDPLLQGRNFSYLDTQIKRLGSTNFTHLPINAPKCPFHTFQQDGHMAMRNPVGRANYQ
CCCCCCCCCCCCHHHHHHHHHHCCCCCEEECCCCCCCCCHHHCCCCCCHHCCCCCCCCCC
PNSWDEGPRESPQKGFRSFAEAEAGPKARLRAESFADHYSQARQFYISQHPVEQGHIASA
CCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
LTFELSKVHTPVIRERIVSHLLNIDDALARKVADALGLKAMPKPADAGAPTRTDLPASDA
HHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHH
LSILKNGPGRFEGRKLGILVTDGTDAALLNALKQALTKAGAKFEIIAPKVGGAKASDGSW
HHHHHCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCC
MDAQQMIAGAPSVLYDAIALLAAKPAMAGLLRESTARDFVADAFAHCKFIGFVEAAAPLL
CCHHHHHHCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DKAGVVEDEAVIPLASAKDVAGFITRLGDLRLWAREPKVKLG
HHCCCCCCCCEEECCCHHHHHHHHHHHHCCEEEECCCCCCCC
>Mature Secondary Structure 
AKQASKLAGTAATIHDQKLQRGEGGELHQTASGSTAVLTTAQGGPVSDDQNSLRIGARG
CCCHHHHHCCHHHHHHHHHHCCCCCCEEECCCCCEEEEEECCCCCCCCCCCCEEECCCC
PTVLEDFHFREKIFHFDHERIPERVVHARGYGAHGYFETYESLAKYTRADIFQRAGEKTP
CHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCC
AFVRFSTVAGNKGSADLARDVRGFAVKLYTQEGNWDIVGNNMPVFFIQDAIKFPDLIHAA
CEEEEEEECCCCCCHHHHHHHCCEEEEEEEECCCEEEECCCCCEEEECCHHCCHHHHHHH
KAEPNSDFPQAQTAHDNFWDFISLTPESMHMIMWAMSDRAIPRSLRFMEGFGVHTFRLLN
CCCCCCCCCCCCCCCCCCHHHEEECHHHHHHHHHHHCCCCCHHHHHHHHCCCCEEEEEEC
AKDESTFVKFLWKPKLGLQSVAWNEAVKINGADPDFHRRDLWDAIHAGNFPEWELQLQLF
CCCCCCEEHEEECCCCCCHHHCCCCEEEECCCCCCHHHHHHHHHHHCCCCCCHHHHHHHH
DQAFADSFDFDILDPTKLIPEEVLPPIAVGRLVLDRMPDNFFAETEQVAFMTQNVPPGVD
HHHHHCCCCCCCCCCHHHCHHHHCCHHHHHHHHHHHCCCHHHHCCHHHEEEECCCCCCCC
FSNDPLLQGRNFSYLDTQIKRLGSTNFTHLPINAPKCPFHTFQQDGHMAMRNPVGRANYQ
CCCCCCCCCCCCHHHHHHHHHHCCCCCEEECCCCCCCCCHHHCCCCCCHHCCCCCCCCCC
PNSWDEGPRESPQKGFRSFAEAEAGPKARLRAESFADHYSQARQFYISQHPVEQGHIASA
CCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
LTFELSKVHTPVIRERIVSHLLNIDDALARKVADALGLKAMPKPADAGAPTRTDLPASDA
HHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHH
LSILKNGPGRFEGRKLGILVTDGTDAALLNALKQALTKAGAKFEIIAPKVGGAKASDGSW
HHHHHCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCC
MDAQQMIAGAPSVLYDAIALLAAKPAMAGLLRESTARDFVADAFAHCKFIGFVEAAAPLL
CCHHHHHHCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DKAGVVEDEAVIPLASAKDVAGFITRLGDLRLWAREPKVKLG
HHCCCCCCCCEEECCCHHHHHHHHHHHHCCEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10198032; 11481431 [H]