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The map label for this gene is htpG

Identifier: 13471897

GI number: 13471897

Start: 1654638

End: 1656524

Strand: Direct

Name: htpG

Synonym: mlr2017

Alternate gene names: 13471897

Gene position: 1654638-1656524 (Clockwise)

Preceding gene: 13471896

Following gene: 13471899

Centisome position: 23.52

GC content: 66.35

Gene sequence:

>1887_bases
ATGACGACGGACACGAAAGCGACGGAAACCAGGGCATTCGAGGCGGATGTTTCGCGGCTGCTGCACATGATGGTGCATTC
GGTCTATTCCGATAAGGACGTGTTCCTGCGCGAGCTGATTTCCAACGCCGCCGACGCCTGCGAAAAGCTGCGCTTCGAGG
CCGTCAGCCGTCCCGAATTGCTGGGCGACGATCCCAAGCCGCGCATTTCGATTTCGGCCGATCCGGACAACAAGGAGATC
ACCGTCGAGGACAACGGCATCGGCATGAGCCGCGACGACATGGCCGAGGCCCTGGGCACGATCGCCCGCTCGGGCACGCG
CGCCTTCATCGAGCGCGTCGGCTCAGGCACGGAGGACACGCAGCTCATCGGCCAGTTCGGCGTCGGCTTCTATTCCGCCT
TCATGGTCGCCGACCGCGTCGATGTCATCAGCCGCCTGGCCGGAAGCGAAGAGGCCTGGCGCTGGTCCTCCGACGGCAAG
GGTTCCTACGAAATCGCCCCCGCCCCTCTCGAAGCAGCACCCAGGCGCGGCACCCGCGTCGTGCTCCATCTGATGGACGA
CGCCGTTTCCTACACCGGCTCCTACCGGCTCGAGCAGTTGGCCAAGTCGCAGTCGGGCCATGTGCCGGTGCCGATCACGC
TCATCGAAAAACCCGGCGCCGAGGCGCGCGACATTGCCGATGGCACGGCACTCTGGGTGCGACCGAAGAGCGAGATCAAG
CCCGAGGAATATACCGACTTCTACCGCAGCGTCGCCGGCCAGTATGACGAGCCGGCCGCCACCATCCATTTCCGCGCCGA
GGGCCGGCAGGAATACTCCGTGCTTGCCTTCGTGCCCGGCTCGCGCCCGTTCGATCTGTTCGACCAGGACCGCAAGGGCC
GCATGAAGCTCTATGTGCGCCGCGTCTTCATCACCGACGATGCCGACCTGCTGCCGCGCTATCTGCGCTTCGTGCGCGGC
CTGGTCGATTCCGCCGACCTGCCGCTCAACGTCTCGCGCGAAATGATCCAGGAAAGCCCGCTGCTGGCCTCGATCCGCAA
GGGCCTGACCAACCGCGTGCTGGGCGACCTCGCCAAGCTGGCGGAGAACGAGGCCGAGGCCTATGCCAAGGTCTGGGAGA
ATTTCGGCGTCGTCCTGAAGGAAGGGCTCTACGAGGATTACGAGCGGCGCGAGCAATTGCTGAAGCTCGCCCGCTTCCAC
TCGACCGCCTCGGGCGAAGGCTGGCGCGGCCTGGCCGACTATGTCGCGGCGATGAAGGAAGGCCAGAAGGCGATCTTCTT
CATGGCCGGCGACGACCGCGCCAGGCTCGAAGCCTCGCCGCAGCTCGAAGGTTTCAAGGCGCGCGGCATCGAGGTGCTGC
TGCTCACCGACCCGGTCGACAGTTTCTGGGTGACGATGGCGCCGGACTTCGACGGCAAGCCGTTCAAGTCGGTGACGCAA
GGCGTCGCCGAACTGTCCGACATTCCGCTGCTCGACGACGCAAAGAAGCCGGATACGGCTGCAGCGCCGGAGGTCGACGG
CTTCCTGGCCTTCGTCAAATCGGCGCTTGGCGATGCCGTCTCGGATGTGAAGGCCTCCGACCGCCTGACCGAGAGCGCCG
TCTGCCTGGTCGCGCCCGAACATGGCCCCGACCGGCAGTTCGAGCGGCTGATGAACGCCGCCGGCCGCCTCGACAAGGCG
GCCAAGCCCATCCTCGAAATCAACCCGCGCCACGAGCGCGTGCTGGCGCTCGCCGGCCTCGGCGACGAGGACCAGGCCTT
CAAGGATGACGCGGCCCATCTCCTCTACGACGAGGCGCGCGTGCTCGACGGCGACAAGCCGGCCGACGCCAGGGCATTCT
CGGAGCGTCTGGCGCGGCTGATCGCACGCGGCATCGCGAAGGGCTGA

Upstream 100 bases:

>100_bases
GCACACTGAACGCAGTTGCCAGCACCGCAAAAAATGGTTGAAAGGAAAGTCCCGAACGCGCCCGGCGCGGCGGGCGGATG
AACAGCGTGGGAAAATCTGA

Downstream 100 bases:

>100_bases
GCGCAGGCCGATTCTGGTAAAATCGACGCCGATCGCCCCGGACGCTCCGGCGACGTTTCGCCTCCAGCGAGTGCTAAAAA
GCCTGGGTGCCGCCAAGCAC

Product: heat shock protein 90

Products: NA

Alternate protein names: Heat shock protein htpG; High temperature protein G

Number of amino acids: Translated: 628; Mature: 627

Protein sequence:

>628_residues
MTTDTKATETRAFEADVSRLLHMMVHSVYSDKDVFLRELISNAADACEKLRFEAVSRPELLGDDPKPRISISADPDNKEI
TVEDNGIGMSRDDMAEALGTIARSGTRAFIERVGSGTEDTQLIGQFGVGFYSAFMVADRVDVISRLAGSEEAWRWSSDGK
GSYEIAPAPLEAAPRRGTRVVLHLMDDAVSYTGSYRLEQLAKSQSGHVPVPITLIEKPGAEARDIADGTALWVRPKSEIK
PEEYTDFYRSVAGQYDEPAATIHFRAEGRQEYSVLAFVPGSRPFDLFDQDRKGRMKLYVRRVFITDDADLLPRYLRFVRG
LVDSADLPLNVSREMIQESPLLASIRKGLTNRVLGDLAKLAENEAEAYAKVWENFGVVLKEGLYEDYERREQLLKLARFH
STASGEGWRGLADYVAAMKEGQKAIFFMAGDDRARLEASPQLEGFKARGIEVLLLTDPVDSFWVTMAPDFDGKPFKSVTQ
GVAELSDIPLLDDAKKPDTAAAPEVDGFLAFVKSALGDAVSDVKASDRLTESAVCLVAPEHGPDRQFERLMNAAGRLDKA
AKPILEINPRHERVLALAGLGDEDQAFKDDAAHLLYDEARVLDGDKPADARAFSERLARLIARGIAKG

Sequences:

>Translated_628_residues
MTTDTKATETRAFEADVSRLLHMMVHSVYSDKDVFLRELISNAADACEKLRFEAVSRPELLGDDPKPRISISADPDNKEI
TVEDNGIGMSRDDMAEALGTIARSGTRAFIERVGSGTEDTQLIGQFGVGFYSAFMVADRVDVISRLAGSEEAWRWSSDGK
GSYEIAPAPLEAAPRRGTRVVLHLMDDAVSYTGSYRLEQLAKSQSGHVPVPITLIEKPGAEARDIADGTALWVRPKSEIK
PEEYTDFYRSVAGQYDEPAATIHFRAEGRQEYSVLAFVPGSRPFDLFDQDRKGRMKLYVRRVFITDDADLLPRYLRFVRG
LVDSADLPLNVSREMIQESPLLASIRKGLTNRVLGDLAKLAENEAEAYAKVWENFGVVLKEGLYEDYERREQLLKLARFH
STASGEGWRGLADYVAAMKEGQKAIFFMAGDDRARLEASPQLEGFKARGIEVLLLTDPVDSFWVTMAPDFDGKPFKSVTQ
GVAELSDIPLLDDAKKPDTAAAPEVDGFLAFVKSALGDAVSDVKASDRLTESAVCLVAPEHGPDRQFERLMNAAGRLDKA
AKPILEINPRHERVLALAGLGDEDQAFKDDAAHLLYDEARVLDGDKPADARAFSERLARLIARGIAKG
>Mature_627_residues
TTDTKATETRAFEADVSRLLHMMVHSVYSDKDVFLRELISNAADACEKLRFEAVSRPELLGDDPKPRISISADPDNKEIT
VEDNGIGMSRDDMAEALGTIARSGTRAFIERVGSGTEDTQLIGQFGVGFYSAFMVADRVDVISRLAGSEEAWRWSSDGKG
SYEIAPAPLEAAPRRGTRVVLHLMDDAVSYTGSYRLEQLAKSQSGHVPVPITLIEKPGAEARDIADGTALWVRPKSEIKP
EEYTDFYRSVAGQYDEPAATIHFRAEGRQEYSVLAFVPGSRPFDLFDQDRKGRMKLYVRRVFITDDADLLPRYLRFVRGL
VDSADLPLNVSREMIQESPLLASIRKGLTNRVLGDLAKLAENEAEAYAKVWENFGVVLKEGLYEDYERREQLLKLARFHS
TASGEGWRGLADYVAAMKEGQKAIFFMAGDDRARLEASPQLEGFKARGIEVLLLTDPVDSFWVTMAPDFDGKPFKSVTQG
VAELSDIPLLDDAKKPDTAAAPEVDGFLAFVKSALGDAVSDVKASDRLTESAVCLVAPEHGPDRQFERLMNAAGRLDKAA
KPILEINPRHERVLALAGLGDEDQAFKDDAAHLLYDEARVLDGDKPADARAFSERLARLIARGIAKG

Specific function: Molecular chaperone. Has ATPase activity

COG id: COG0326

COG function: function code O; Molecular chaperone, HSP90 family

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 90 family

Homologues:

Organism=Homo sapiens, GI20149594, Length=684, Percent_Identity=35.233918128655, Blast_Score=397, Evalue=1e-110,
Organism=Homo sapiens, GI155722983, Length=634, Percent_Identity=33.2807570977918, Blast_Score=352, Evalue=5e-97,
Organism=Homo sapiens, GI4507677, Length=413, Percent_Identity=37.5302663438257, Blast_Score=259, Evalue=7e-69,
Organism=Homo sapiens, GI154146191, Length=406, Percent_Identity=36.4532019704434, Blast_Score=256, Evalue=6e-68,
Organism=Homo sapiens, GI153792590, Length=406, Percent_Identity=36.4532019704434, Blast_Score=253, Evalue=3e-67,
Organism=Escherichia coli, GI1786679, Length=632, Percent_Identity=42.5632911392405, Blast_Score=491, Evalue=1e-140,
Organism=Caenorhabditis elegans, GI17559162, Length=673, Percent_Identity=34.6210995542348, Blast_Score=401, Evalue=1e-112,
Organism=Caenorhabditis elegans, GI17542208, Length=675, Percent_Identity=33.7777777777778, Blast_Score=355, Evalue=3e-98,
Organism=Caenorhabditis elegans, GI115535205, Length=633, Percent_Identity=33.0173775671406, Blast_Score=309, Evalue=3e-84,
Organism=Caenorhabditis elegans, GI115535167, Length=420, Percent_Identity=36.1904761904762, Blast_Score=249, Evalue=4e-66,
Organism=Saccharomyces cerevisiae, GI6323840, Length=679, Percent_Identity=34.9042709867452, Blast_Score=401, Evalue=1e-112,
Organism=Saccharomyces cerevisiae, GI6325016, Length=683, Percent_Identity=34.2606149341142, Blast_Score=397, Evalue=1e-111,
Organism=Drosophila melanogaster, GI17647529, Length=684, Percent_Identity=33.6257309941521, Blast_Score=394, Evalue=1e-110,
Organism=Drosophila melanogaster, GI21357739, Length=678, Percent_Identity=33.9233038348083, Blast_Score=352, Evalue=4e-97,
Organism=Drosophila melanogaster, GI24586016, Length=650, Percent_Identity=33.3846153846154, Blast_Score=329, Evalue=4e-90,

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 2419 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): HTPG_RHILO (Q98JB6)

Other databases:

- EMBL:   BA000012
- RefSeq:   NP_103464.1
- ProteinModelPortal:   Q98JB6
- GeneID:   1226125
- GenomeReviews:   BA000012_GR
- KEGG:   mlo:mlr2017
- NMPDR:   fig|266835.1.peg.1568
- HOGENOM:   HBG631012
- OMA:   AIYYITA
- ProtClustDB:   PRK05218
- GO:   GO:0005737
- HAMAP:   MF_00505
- InterPro:   IPR003594
- InterPro:   IPR019805
- InterPro:   IPR001404
- InterPro:   IPR020575
- InterPro:   IPR020568
- Gene3D:   G3DSA:3.30.565.10
- PANTHER:   PTHR11528
- PIRSF:   PIRSF002583
- PRINTS:   PR00775
- SMART:   SM00387

Pfam domain/function: PF02518 HATPase_c; PF00183 HSP90; SSF55874 ATP_bd_ATPase; SSF54211 Ribosomal_S5_D2-typ_fold

EC number: NA

Molecular weight: Translated: 69284; Mature: 69153

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: PS00298 HSP90

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTDTKATETRAFEADVSRLLHMMVHSVYSDKDVFLRELISNAADACEKLRFEAVSRPEL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
LGDDPKPRISISADPDNKEITVEDNGIGMSRDDMAEALGTIARSGTRAFIERVGSGTEDT
CCCCCCCCEEEECCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
QLIGQFGVGFYSAFMVADRVDVISRLAGSEEAWRWSSDGKGSYEIAPAPLEAAPRRGTRV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCCCEEECCCCCCCCCCCCCEE
VLHLMDDAVSYTGSYRLEQLAKSQSGHVPVPITLIEKPGAEARDIADGTALWVRPKSEIK
EHHHHHHHHHHCCCHHHHHHHHCCCCCCCEEEEEEECCCCCHHHCCCCCEEEECCHHCCC
PEEYTDFYRSVAGQYDEPAATIHFRAEGRQEYSVLAFVPGSRPFDLFDQDRKGRMKLYVR
CHHHHHHHHHHCCCCCCCCEEEEEEECCCCCEEEEEECCCCCCCCCCCCCCCCCEEEEEE
RVFITDDADLLPRYLRFVRGLVDSADLPLNVSREMIQESPLLASIRKGLTNRVLGDLAKL
EEEECCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHH
AENEAEAYAKVWENFGVVLKEGLYEDYERREQLLKLARFHSTASGEGWRGLADYVAAMKE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHC
GQKAIFFMAGDDRARLEASPQLEGFKARGIEVLLLTDPVDSFWVTMAPDFDGKPFKSVTQ
CCEEEEEEECCCCCCCCCCCCCCCEECCCEEEEEEECCCCCCEEEECCCCCCCCHHHHHH
GVAELSDIPLLDDAKKPDTAAAPEVDGFLAFVKSALGDAVSDVKASDRLTESAVCLVAPE
HHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECC
HGPDRQFERLMNAAGRLDKAAKPILEINPRHERVLALAGLGDEDQAFKDDAAHLLYDEAR
CCCCHHHHHHHHHHHHHHHHCCCCEECCCCHHEEEEEECCCCCHHHHHHHHHHHHHHHHH
VLDGDKPADARAFSERLARLIARGIAKG
HCCCCCCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TTDTKATETRAFEADVSRLLHMMVHSVYSDKDVFLRELISNAADACEKLRFEAVSRPEL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
LGDDPKPRISISADPDNKEITVEDNGIGMSRDDMAEALGTIARSGTRAFIERVGSGTEDT
CCCCCCCCEEEECCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
QLIGQFGVGFYSAFMVADRVDVISRLAGSEEAWRWSSDGKGSYEIAPAPLEAAPRRGTRV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCCCEEECCCCCCCCCCCCCEE
VLHLMDDAVSYTGSYRLEQLAKSQSGHVPVPITLIEKPGAEARDIADGTALWVRPKSEIK
EHHHHHHHHHHCCCHHHHHHHHCCCCCCCEEEEEEECCCCCHHHCCCCCEEEECCHHCCC
PEEYTDFYRSVAGQYDEPAATIHFRAEGRQEYSVLAFVPGSRPFDLFDQDRKGRMKLYVR
CHHHHHHHHHHCCCCCCCCEEEEEEECCCCCEEEEEECCCCCCCCCCCCCCCCCEEEEEE
RVFITDDADLLPRYLRFVRGLVDSADLPLNVSREMIQESPLLASIRKGLTNRVLGDLAKL
EEEECCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHH
AENEAEAYAKVWENFGVVLKEGLYEDYERREQLLKLARFHSTASGEGWRGLADYVAAMKE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHC
GQKAIFFMAGDDRARLEASPQLEGFKARGIEVLLLTDPVDSFWVTMAPDFDGKPFKSVTQ
CCEEEEEEECCCCCCCCCCCCCCCEECCCEEEEEEECCCCCCEEEECCCCCCCCHHHHHH
GVAELSDIPLLDDAKKPDTAAAPEVDGFLAFVKSALGDAVSDVKASDRLTESAVCLVAPE
HHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECC
HGPDRQFERLMNAAGRLDKAAKPILEINPRHERVLALAGLGDEDQAFKDDAAHLLYDEAR
CCCCHHHHHHHHHHHHHHHHCCCCEECCCCHHEEEEEECCCCCHHHHHHHHHHHHHHHHH
VLDGDKPADARAFSERLARLIARGIAKG
HCCCCCCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11214968