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The map label for this gene is ydfI [H]

Identifier: 13471794

GI number: 13471794

Start: 1550992

End: 1552485

Strand: Direct

Name: ydfI [H]

Synonym: mlr1886

Alternate gene names: 13471794

Gene position: 1550992-1552485 (Clockwise)

Preceding gene: 13471793

Following gene: 13471795

Centisome position: 22.04

GC content: 66.47

Gene sequence:

>1494_bases
TTGCTGGACCAGCTTCCGGCCGCTGTCCGGACGCCTGGATATGACCGGACAACCCTTGCGCCAGGCATGGCGCATCTCGG
CGTCGGCGCGTTCCACCGCTGCCATCAAGCCGAATACACCGATGATTTGCTGGCGCGCCAGTTCGACCGCTGGGGCGTTG
TCGGCATCAACATCCGTCCGCCCACCCTTGCCGACACGCTCGGCCGGCAGAGCGGGCTCTACACAAGGCTGATCCGCGAA
AACAGCCATATCGAGGCCCGCATCATCGGCAGCATCGTGAAGGTGGTGGACAGCCAGGCAAGTGCCGGGCCGGCACTCAC
GGTGCTGTCCTCACGCGATATCGAACTGGTGACGATGACGGTGACGGAGAAAGGCTATTGCCACATCCCGTCGAGCGGCG
CGCTCGATCTCGGCCATCCCGACATTGTCCATGATCTCGCCAACCCTCATGCGCCGCGCAGCGTGCCCGGCATCCTCGCG
CGGGCGCTGGAACTGCGCCGGGCCACGCATGGCCGGCCATTGACGCTGCTCTCCTGCGACAACATCCCGGCCAACGGCGT
CATCCTGGAAACTGTCGTGCGGAGCTTTGCCGAGCGGCGCGGCAATGGCTTGGCCGAATGGATCGCCGCCAATGCCGCCT
TCCCGTCGGCCATGGTCGACCGCATCGCGCCGGCGGTGACGCAGCACGATCTGGACAGCGTCGAGCAATGGTTCGGCTAC
CGCGACGCCGCCGTCGCCGTCGGCGAGCCGTTCCGGCAATGGGTGATCGAGCAGAAATTCGCCGGCCGCGTGCCGCGCTG
GGACCTGGTCGGCGCGACCTTTGTCGACGATGTCACGCCGTTCGAGCATCTCAAGATGCGGGTGCTGAACGGCACCCAGA
CGACGCTCGCCACGCTCGGCGTGCTGGCCGGGCTGGAGCATACATCGGATGCCATCGCCGACCCGCTGCTATCGGCCTTC
ACCAGGCGCATGCTGGTCGAGGAAACGCTGCCGACGCTGATGCCGGTGCCCGGCATGGACCCATCGGCCTATGTCGAGCA
GAGCCTCGGCCGGCTTAAGAACACGGCGATCCGCCACCGCAACCACCAGATCGCCACCGACGGCTCGCAGAAGATCGTGC
AGCGCCTGCTCAACCCGATCCGCGACCGCTTGCGGCTGGGCCAGACCATCGGCCTGCTGTCGGTGCCGGTCGCCGGCTGG
ATGGCCTATCTCATCCAGGCCTCGGACCGCTTCGGCAAACGCTGGCCGGTCTCCGATCCCTATGCGGGCAAAGTCGCCGA
GATCGCCGACGCAACCGGGCGCGATGCGCCGGCTTTGGCCTCGGCCATCCTTGCCATCGACACGATCTTCGACCCCGGCC
TTGCCGCGAACGCTGCGTTTCGCGCGGCCGTGACTTCGGCGCTGGGCGAGCTGCTTTCGGACGATCCGATGGCGGCTGTC
CGGCACGGTCTCGAACAAGATGAGGTCGCAAGGTTGAAACGATCCAAACAATAG

Upstream 100 bases:

>100_bases
CCGGGCCGATGACCGGCGCTGTGATCGACCAGGAGCAGTCGGTGATCGGGGCGAACCGGTGAACGCGGCTTCGACAGCGC
CGGAAACACTCGGTCCAGCC

Downstream 100 bases:

>100_bases
GCATTATGAAGGCTGGGAGGCACTATGAAACTTGGACTGCTCACCGCACCCTTCGCGGAGACGCCGCTTGCCGATGTCGC
CGCCTGGGCCAGCTCTGCCG

Product: D-mannonate oxidoreductase

Products: D-fructuronate; NADH [C]

Alternate protein names: NA

Number of amino acids: Translated: 497; Mature: 497

Protein sequence:

>497_residues
MLDQLPAAVRTPGYDRTTLAPGMAHLGVGAFHRCHQAEYTDDLLARQFDRWGVVGINIRPPTLADTLGRQSGLYTRLIRE
NSHIEARIIGSIVKVVDSQASAGPALTVLSSRDIELVTMTVTEKGYCHIPSSGALDLGHPDIVHDLANPHAPRSVPGILA
RALELRRATHGRPLTLLSCDNIPANGVILETVVRSFAERRGNGLAEWIAANAAFPSAMVDRIAPAVTQHDLDSVEQWFGY
RDAAVAVGEPFRQWVIEQKFAGRVPRWDLVGATFVDDVTPFEHLKMRVLNGTQTTLATLGVLAGLEHTSDAIADPLLSAF
TRRMLVEETLPTLMPVPGMDPSAYVEQSLGRLKNTAIRHRNHQIATDGSQKIVQRLLNPIRDRLRLGQTIGLLSVPVAGW
MAYLIQASDRFGKRWPVSDPYAGKVAEIADATGRDAPALASAILAIDTIFDPGLAANAAFRAAVTSALGELLSDDPMAAV
RHGLEQDEVARLKRSKQ

Sequences:

>Translated_497_residues
MLDQLPAAVRTPGYDRTTLAPGMAHLGVGAFHRCHQAEYTDDLLARQFDRWGVVGINIRPPTLADTLGRQSGLYTRLIRE
NSHIEARIIGSIVKVVDSQASAGPALTVLSSRDIELVTMTVTEKGYCHIPSSGALDLGHPDIVHDLANPHAPRSVPGILA
RALELRRATHGRPLTLLSCDNIPANGVILETVVRSFAERRGNGLAEWIAANAAFPSAMVDRIAPAVTQHDLDSVEQWFGY
RDAAVAVGEPFRQWVIEQKFAGRVPRWDLVGATFVDDVTPFEHLKMRVLNGTQTTLATLGVLAGLEHTSDAIADPLLSAF
TRRMLVEETLPTLMPVPGMDPSAYVEQSLGRLKNTAIRHRNHQIATDGSQKIVQRLLNPIRDRLRLGQTIGLLSVPVAGW
MAYLIQASDRFGKRWPVSDPYAGKVAEIADATGRDAPALASAILAIDTIFDPGLAANAAFRAAVTSALGELLSDDPMAAV
RHGLEQDEVARLKRSKQ
>Mature_497_residues
MLDQLPAAVRTPGYDRTTLAPGMAHLGVGAFHRCHQAEYTDDLLARQFDRWGVVGINIRPPTLADTLGRQSGLYTRLIRE
NSHIEARIIGSIVKVVDSQASAGPALTVLSSRDIELVTMTVTEKGYCHIPSSGALDLGHPDIVHDLANPHAPRSVPGILA
RALELRRATHGRPLTLLSCDNIPANGVILETVVRSFAERRGNGLAEWIAANAAFPSAMVDRIAPAVTQHDLDSVEQWFGY
RDAAVAVGEPFRQWVIEQKFAGRVPRWDLVGATFVDDVTPFEHLKMRVLNGTQTTLATLGVLAGLEHTSDAIADPLLSAF
TRRMLVEETLPTLMPVPGMDPSAYVEQSLGRLKNTAIRHRNHQIATDGSQKIVQRLLNPIRDRLRLGQTIGLLSVPVAGW
MAYLIQASDRFGKRWPVSDPYAGKVAEIADATGRDAPALASAILAIDTIFDPGLAANAAFRAAVTSALGELLSDDPMAAV
RHGLEQDEVARLKRSKQ

Specific function: Unknown

COG id: COG0246

COG function: function code G; Mannitol-1-phosphate/altronate dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mannitol dehydrogenase family. UxuB subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787823, Length=479, Percent_Identity=39.874739039666, Blast_Score=331, Evalue=7e-92,
Organism=Escherichia coli, GI1790779, Length=470, Percent_Identity=40.2127659574468, Blast_Score=325, Evalue=3e-90,
Organism=Escherichia coli, GI1788497, Length=471, Percent_Identity=37.3673036093418, Blast_Score=316, Evalue=3e-87,
Organism=Escherichia coli, GI48994885, Length=416, Percent_Identity=25.2403846153846, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1790028, Length=248, Percent_Identity=25.8064516129032, Blast_Score=70, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6324401, Length=490, Percent_Identity=33.469387755102, Blast_Score=281, Evalue=2e-76,
Organism=Saccharomyces cerevisiae, GI6320765, Length=490, Percent_Identity=33.469387755102, Blast_Score=281, Evalue=2e-76,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR000669
- InterPro:   IPR013118
- InterPro:   IPR023027
- InterPro:   IPR013131
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01232 Mannitol_dh; PF08125 Mannitol_dh_C [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 53923; Mature: 53923

Theoretical pI: Translated: 7.08; Mature: 7.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDQLPAAVRTPGYDRTTLAPGMAHLGVGAFHRCHQAEYTDDLLARQFDRWGVVGINIRP
CCCCCCCHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCC
PTLADTLGRQSGLYTRLIRENSHIEARIIGSIVKVVDSQASAGPALTVLSSRDIELVTMT
CHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCEEEEECCCCEEEEEEE
VTEKGYCHIPSSGALDLGHPDIVHDLANPHAPRSVPGILARALELRRATHGRPLTLLSCD
EECCCEEECCCCCCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECC
NIPANGVILETVVRSFAERRGNGLAEWIAANAAFPSAMVDRIAPAVTQHDLDSVEQWFGY
CCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
RDAAVAVGEPFRQWVIEQKFAGRVPRWDLVGATFVDDVTPFEHLKMRVLNGTQTTLATLG
CHHHHHHCHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCCHHHHHHHHHCCCHHHHHHHH
VLAGLEHTSDAIADPLLSAFTRRMLVEETLPTLMPVPGMDPSAYVEQSLGRLKNTAIRHR
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHC
NHQIATDGSQKIVQRLLNPIRDRLRLGQTIGLLSVPVAGWMAYLIQASDRFGKRWPVSDP
CCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
YAGKVAEIADATGRDAPALASAILAIDTIFDPGLAANAAFRAAVTSALGELLSDDPMAAV
CCCHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHH
RHGLEQDEVARLKRSKQ
HCCCCHHHHHHHHHCCC
>Mature Secondary Structure
MLDQLPAAVRTPGYDRTTLAPGMAHLGVGAFHRCHQAEYTDDLLARQFDRWGVVGINIRP
CCCCCCCHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCC
PTLADTLGRQSGLYTRLIRENSHIEARIIGSIVKVVDSQASAGPALTVLSSRDIELVTMT
CHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCEEEEECCCCEEEEEEE
VTEKGYCHIPSSGALDLGHPDIVHDLANPHAPRSVPGILARALELRRATHGRPLTLLSCD
EECCCEEECCCCCCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECC
NIPANGVILETVVRSFAERRGNGLAEWIAANAAFPSAMVDRIAPAVTQHDLDSVEQWFGY
CCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
RDAAVAVGEPFRQWVIEQKFAGRVPRWDLVGATFVDDVTPFEHLKMRVLNGTQTTLATLG
CHHHHHHCHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCCHHHHHHHHHCCCHHHHHHHH
VLAGLEHTSDAIADPLLSAFTRRMLVEETLPTLMPVPGMDPSAYVEQSLGRLKNTAIRHR
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHC
NHQIATDGSQKIVQRLLNPIRDRLRLGQTIGLLSVPVAGWMAYLIQASDRFGKRWPVSDP
CCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
YAGKVAEIADATGRDAPALASAILAIDTIFDPGLAANAAFRAAVTSALGELLSDDPMAAV
CCCHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHH
RHGLEQDEVARLKRSKQ
HCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: D-mannonate; NAD(+) [C]

Specific reaction: D-mannonate + NAD(+) = D-fructuronate + NADH [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]