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The map label for this gene is mocR [H]

Identifier: 13471750

GI number: 13471750

Start: 1506248

End: 1507690

Strand: Direct

Name: mocR [H]

Synonym: mlr1821

Alternate gene names: 13471750

Gene position: 1506248-1507690 (Clockwise)

Preceding gene: 13471746

Following gene: 13471752

Centisome position: 21.41

GC content: 69.02

Gene sequence:

>1443_bases
ATGGCATTGGTCGAGAAAAGAACCAATCACAGCGATAAAATTCAGACCAATCCGCCGGATTGGTCGGCGCTGATCCCGGT
CCTGCCGGGCGACGGACCGCGCAGCCGCGAGCTTTACGCGGCGCTGCGGCGGCTGATCGAGACCGGCGCGCTGGCCGCCG
GCGCCAAGCTGCCGACCACCCGCGACCTTGCCCGGCGCTTCGGCCTGTCGCGTTCGGCGGCGGTCGCCTGTTTCGAAATG
CTGATCTCGGAGGGCTTTGCCGTGGCCAAGGTCGGCGCCGGCACCTTCGTCGCGCCCGATGTGCCATATCTGCCGACAAC
GCTGGTCAAGCCGCGCCCGCCGGAGATCGACGCCGCTATCTCGCTGCCTTGCGGCCTTGGCGTGGCGGTGTCCGACCCGC
GCACGCTCAACCTGTTCCGCATCCTGCTGTCGCGCCACCTCGCCCGCCCCGGCCCCGAGCATTTCCGCTACGGCGATCCG
CGCGGCGGCCTGCCGCTGCGCACCGCGATTGCCACGTATCTACGAACCGCGCGCGGCGTGCGCTGCGACGCCGGCCAGAT
CCTGCTGACCTCGGGCACGCAGCAGGGGCTCGACCTGCTGGCGCGCGCGGCACTTCGCCCCGGCGACGCCGTCTGGCTGG
AAAACCCCTGCTATCCCATGGCGCACGCCGTGCTGGCCGGCAGCGGCGCCAGGATTGTCGCCGTGACGGTCGACGCCGAG
GGGCTCGATCCCGAGATCGGCGAACGTCTCTGCCCAAAGGCACGCGCGGCCTATGTCACGCCCTCGCACCAATATCCGCT
CGGCGTGACCATGACGATGCGCCGGCGGCTTGCCCTGCTCGACTGGGCGCGGCGCAACGAGGCCTGGATCATCGAGGACG
ATTACGACAGCGAGTTCCGCTATGCCGGCCCGCCGTTGACCTCGCTGCAAGGCATGGATGGCGCGGGCCGCGTCGCCTAT
CTCGGCACCTTCTCCAAGGTGCTCTTCCCCGGCCTGCGCATCGGCTATGTCGTGGTGCCGGAACCCTTGCTCGATGCCGT
CATGGCGATCAGGGCGCGCTCCGACCGTTACCCCTCGACGCTGGCCGAAGGCGCGCTGACCGACCTGTTGAACGAGGGCC
ATTTCGCCGCGCATCTCCGGCGCGTGCGTCGCCGTGTGCAAGCCGCGCGCGACGTGCTGGTGGCGGGCCTCCAGGCGCAT
TGCGGCGACAGGCTCGATGTGACGGTGCCCGAACAGGGGTTGCATCTGATGGCGATGTTAAGGGGCAACGGACCGGACAC
GGCGATCGTCGAGGCGGCGAAGGCCGTGGGTGTCGGCGTGCGGGCGCTGTCCGCGATGTTCATCGACGGCGCGCCGAGAC
ATGGCCTGGTGCTGGGCTTTTCCGGGTTTTCGGATGAGGAGTTGAGGGGAGCGACGGTAAGGTTAGGCGGGGTGATGCGG
TAA

Upstream 100 bases:

>100_bases
TCATGCAGGCGCTTGACCCGGTTGCGGCTGGTGGTCGGAAAGCTGGCGGAAACGTCGTTCACGGCTTGCGTCCTCGGCTG
TTGTCTGCCAACCATGCGCC

Downstream 100 bases:

>100_bases
CCGCTTAATCCGCATCAGCGGCAGGCTTCGCCTTCCCGCACTGCGCCAGCACCTTGCCGATGGCCCCCTTCGAACCCTTC
AGCGGAAAACTGCTCGAACC

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 480; Mature: 479

Protein sequence:

>480_residues
MALVEKRTNHSDKIQTNPPDWSALIPVLPGDGPRSRELYAALRRLIETGALAAGAKLPTTRDLARRFGLSRSAAVACFEM
LISEGFAVAKVGAGTFVAPDVPYLPTTLVKPRPPEIDAAISLPCGLGVAVSDPRTLNLFRILLSRHLARPGPEHFRYGDP
RGGLPLRTAIATYLRTARGVRCDAGQILLTSGTQQGLDLLARAALRPGDAVWLENPCYPMAHAVLAGSGARIVAVTVDAE
GLDPEIGERLCPKARAAYVTPSHQYPLGVTMTMRRRLALLDWARRNEAWIIEDDYDSEFRYAGPPLTSLQGMDGAGRVAY
LGTFSKVLFPGLRIGYVVVPEPLLDAVMAIRARSDRYPSTLAEGALTDLLNEGHFAAHLRRVRRRVQAARDVLVAGLQAH
CGDRLDVTVPEQGLHLMAMLRGNGPDTAIVEAAKAVGVGVRALSAMFIDGAPRHGLVLGFSGFSDEELRGATVRLGGVMR

Sequences:

>Translated_480_residues
MALVEKRTNHSDKIQTNPPDWSALIPVLPGDGPRSRELYAALRRLIETGALAAGAKLPTTRDLARRFGLSRSAAVACFEM
LISEGFAVAKVGAGTFVAPDVPYLPTTLVKPRPPEIDAAISLPCGLGVAVSDPRTLNLFRILLSRHLARPGPEHFRYGDP
RGGLPLRTAIATYLRTARGVRCDAGQILLTSGTQQGLDLLARAALRPGDAVWLENPCYPMAHAVLAGSGARIVAVTVDAE
GLDPEIGERLCPKARAAYVTPSHQYPLGVTMTMRRRLALLDWARRNEAWIIEDDYDSEFRYAGPPLTSLQGMDGAGRVAY
LGTFSKVLFPGLRIGYVVVPEPLLDAVMAIRARSDRYPSTLAEGALTDLLNEGHFAAHLRRVRRRVQAARDVLVAGLQAH
CGDRLDVTVPEQGLHLMAMLRGNGPDTAIVEAAKAVGVGVRALSAMFIDGAPRHGLVLGFSGFSDEELRGATVRLGGVMR
>Mature_479_residues
ALVEKRTNHSDKIQTNPPDWSALIPVLPGDGPRSRELYAALRRLIETGALAAGAKLPTTRDLARRFGLSRSAAVACFEML
ISEGFAVAKVGAGTFVAPDVPYLPTTLVKPRPPEIDAAISLPCGLGVAVSDPRTLNLFRILLSRHLARPGPEHFRYGDPR
GGLPLRTAIATYLRTARGVRCDAGQILLTSGTQQGLDLLARAALRPGDAVWLENPCYPMAHAVLAGSGARIVAVTVDAEG
LDPEIGERLCPKARAAYVTPSHQYPLGVTMTMRRRLALLDWARRNEAWIIEDDYDSEFRYAGPPLTSLQGMDGAGRVAYL
GTFSKVLFPGLRIGYVVVPEPLLDAVMAIRARSDRYPSTLAEGALTDLLNEGHFAAHLRRVRRRVQAARDVLVAGLQAHC
GDRLDVTVPEQGLHLMAMLRGNGPDTAIVEAAKAVGVGVRALSAMFIDGAPRHGLVLGFSGFSDEELRGATVRLGGVMR

Specific function: Could play a regulatory role in the transcription of the moc genes for rhizopine catabolism. Could also have an aminotransferase activity [H]

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=313, Percent_Identity=29.073482428115, Blast_Score=115, Evalue=1e-25,
Organism=Homo sapiens, GI33469970, Length=313, Percent_Identity=29.073482428115, Blast_Score=115, Evalue=1e-25,
Organism=Escherichia coli, GI1790797, Length=465, Percent_Identity=26.6666666666667, Blast_Score=119, Evalue=4e-28,
Organism=Escherichia coli, GI1787710, Length=399, Percent_Identity=27.8195488721804, Blast_Score=117, Evalue=2e-27,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 51629; Mature: 51498

Theoretical pI: Translated: 9.47; Mature: 9.47

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALVEKRTNHSDKIQTNPPDWSALIPVLPGDGPRSRELYAALRRLIETGALAAGAKLPTT
CCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCHHCCCCCCCH
RDLARRFGLSRSAAVACFEMLISEGFAVAKVGAGTFVAPDVPYLPTTLVKPRPPEIDAAI
HHHHHHHCCCHHHHHHHHHHHHHCCCEEEEECCCCEECCCCCCCCCCCCCCCCCCCCCEE
SLPCGLGVAVSDPRTLNLFRILLSRHLARPGPEHFRYGDPRGGLPLRTAIATYLRTARGV
ECCCCCCEEECCCCHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCHHHHHHHHHHHHHCCC
RCDAGQILLTSGTQQGLDLLARAALRPGDAVWLENPCYPMAHAVLAGSGARIVAVTVDAE
CCCCCCEEEECCCHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHCCCCCEEEEEEECCC
GLDPEIGERLCPKARAAYVTPSHQYPLGVTMTMRRRLALLDWARRNEAWIIEDDYDSEFR
CCCHHHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCE
YAGPPLTSLQGMDGAGRVAYLGTFSKVLFPGLRIGYVVVPEPLLDAVMAIRARSDRYPST
ECCCCCCCCCCCCCCCCEEEHHHHHHHHCCCCEEEEEEECHHHHHHHHHHHHCCCCCCHH
LAEGALTDLLNEGHFAAHLRRVRRRVQAARDVLVAGLQAHCGDRLDVTVPEQGLHLMAML
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCEEEEEE
RGNGPDTAIVEAAKAVGVGVRALSAMFIDGAPRHGLVLGFSGFSDEELRGATVRLGGVMR
ECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCEEECCCCCC
>Mature Secondary Structure 
ALVEKRTNHSDKIQTNPPDWSALIPVLPGDGPRSRELYAALRRLIETGALAAGAKLPTT
CCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCHHCCCCCCCH
RDLARRFGLSRSAAVACFEMLISEGFAVAKVGAGTFVAPDVPYLPTTLVKPRPPEIDAAI
HHHHHHHCCCHHHHHHHHHHHHHCCCEEEEECCCCEECCCCCCCCCCCCCCCCCCCCCEE
SLPCGLGVAVSDPRTLNLFRILLSRHLARPGPEHFRYGDPRGGLPLRTAIATYLRTARGV
ECCCCCCEEECCCCHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCHHHHHHHHHHHHHCCC
RCDAGQILLTSGTQQGLDLLARAALRPGDAVWLENPCYPMAHAVLAGSGARIVAVTVDAE
CCCCCCEEEECCCHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHCCCCCEEEEEEECCC
GLDPEIGERLCPKARAAYVTPSHQYPLGVTMTMRRRLALLDWARRNEAWIIEDDYDSEFR
CCCHHHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCE
YAGPPLTSLQGMDGAGRVAYLGTFSKVLFPGLRIGYVVVPEPLLDAVMAIRARSDRYPST
ECCCCCCCCCCCCCCCCEEEHHHHHHHHCCCCEEEEEEECHHHHHHHHHHHHCCCCCCHH
LAEGALTDLLNEGHFAAHLRRVRRRVQAARDVLVAGLQAHCGDRLDVTVPEQGLHLMAML
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCEEEEEE
RGNGPDTAIVEAAKAVGVGVRALSAMFIDGAPRHGLVLGFSGFSDEELRGATVRLGGVMR
ECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7845353 [H]