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The map label for this gene is fabH [H]

Identifier: 13471587

GI number: 13471587

Start: 1334304

End: 1335248

Strand: Reverse

Name: fabH [H]

Synonym: mll1602

Alternate gene names: 13471587

Gene position: 1335248-1334304 (Counterclockwise)

Preceding gene: 13471588

Following gene: 13471586

Centisome position: 18.98

GC content: 63.49

Gene sequence:

>945_bases
GTGAAATCCCGTCATGTCATCGAGCGGGAAGGCATTCTCGACCCGACGCGGATGACGCCGCGCATTCCAGCGCGGCCCGA
CGATGCGCTGTCGCTGGAGGCCGAGTTCGGCATCGCTTCGGCCAGGAAGGCGCTCGACCATGCCGGAGTTGAACCGTCCC
AGATCGACCTGATCATCTGCTCGGCCTCGCACCACCAGCGGCCCTATCCGGCGATCGCCATCGAAATGCAGGAGGCGCTC
GGCACGACCGGCGCCGGCTTCGACATGGGGCTCGGCTGTTCGTCCGCGGCGGCGGCGCTGCACATGGCGGTCAATCTGGT
GCGCTCGGGCGCGCACAAGCGCATCCTGGTAACCACGCCGGAAATCATCACCGGCCATCTCAATTTCCGCGACCGGCAGA
CGCATTTCATCTTCGGCGACGCCTCGGTGTCGATGGTGGTGGAGGGGCTTGCCCAGGGCGACAAACGGCCGGGGCGTTTC
GAGGTGCTGGACACGCGGCTGTGGACGCAGATGTCGAACAACATCCGCACCAATCTGGGCTACCACACCCGCACGGCCCA
GGATGATCCCTACATGATCAATCTGGAAGGCAATCTGATCAAACAGGTCGGCAACAAGGTGTTTAAGGAAGTCACCGTCG
CCGGCCAGAAATTCATCGTCGAGTTCCTGGCCGAGCACGGGCTGACGCCGCAGGCGATCCGGCGCTTCTGGCTGCATCAG
GCGAATGCCCGCATGAATGCGATGATCCTGAAACTGTCGTTCGGCCACGATGTCGATCACGATCGCGCGCCGATGGTTCT
GGAGCGGCTGGGCAACACGGCTGGCGCCGGCGCCATCGTCGCGCTGTCGGAGAACCATGCTGACATGAAGCCCGGTGATT
TCGGCTTGATCTGCGCCTTTGGCGCGGGGTATTCGATAGGCGGCGCGCTTATCCGCATGCTTTGA

Upstream 100 bases:

>100_bases
CTTCAACAGCTGGGTCGACACGGAGAATGCGCGCCGTCAAGGCACCGGCGAGGCGCTGCTGCAGAAATCCGACAGCGACT
TCATCGTCCATGCCTCGGGC

Downstream 100 bases:

>100_bases
GCAATCTCGCGGTGACGCTGGCCTGAAAAGGCCATTCGGACTTTCATCATCAATCGGGCCGCTTAGCGCCCGTCTTCCAA
TCCCGTTCAGCCTGAACCTG

Product: 3-oxoacyl-(acyl carrier protein) synthase III

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III; Beta-ketoacyl-ACP synthase III; KAS III [H]

Number of amino acids: Translated: 314; Mature: 314

Protein sequence:

>314_residues
MKSRHVIEREGILDPTRMTPRIPARPDDALSLEAEFGIASARKALDHAGVEPSQIDLIICSASHHQRPYPAIAIEMQEAL
GTTGAGFDMGLGCSSAAAALHMAVNLVRSGAHKRILVTTPEIITGHLNFRDRQTHFIFGDASVSMVVEGLAQGDKRPGRF
EVLDTRLWTQMSNNIRTNLGYHTRTAQDDPYMINLEGNLIKQVGNKVFKEVTVAGQKFIVEFLAEHGLTPQAIRRFWLHQ
ANARMNAMILKLSFGHDVDHDRAPMVLERLGNTAGAGAIVALSENHADMKPGDFGLICAFGAGYSIGGALIRML

Sequences:

>Translated_314_residues
MKSRHVIEREGILDPTRMTPRIPARPDDALSLEAEFGIASARKALDHAGVEPSQIDLIICSASHHQRPYPAIAIEMQEAL
GTTGAGFDMGLGCSSAAAALHMAVNLVRSGAHKRILVTTPEIITGHLNFRDRQTHFIFGDASVSMVVEGLAQGDKRPGRF
EVLDTRLWTQMSNNIRTNLGYHTRTAQDDPYMINLEGNLIKQVGNKVFKEVTVAGQKFIVEFLAEHGLTPQAIRRFWLHQ
ANARMNAMILKLSFGHDVDHDRAPMVLERLGNTAGAGAIVALSENHADMKPGDFGLICAFGAGYSIGGALIRML
>Mature_314_residues
MKSRHVIEREGILDPTRMTPRIPARPDDALSLEAEFGIASARKALDHAGVEPSQIDLIICSASHHQRPYPAIAIEMQEAL
GTTGAGFDMGLGCSSAAAALHMAVNLVRSGAHKRILVTTPEIITGHLNFRDRQTHFIFGDASVSMVVEGLAQGDKRPGRF
EVLDTRLWTQMSNNIRTNLGYHTRTAQDDPYMINLEGNLIKQVGNKVFKEVTVAGQKFIVEFLAEHGLTPQAIRRFWLHQ
ANARMNAMILKLSFGHDVDHDRAPMVLERLGNTAGAGAIVALSENHADMKPGDFGLICAFGAGYSIGGALIRML

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family [H]

Homologues:

Organism=Escherichia coli, GI1787333, Length=308, Percent_Identity=28.8961038961039, Blast_Score=105, Evalue=4e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C [H]

EC number: =2.3.1.180 [H]

Molecular weight: Translated: 34267; Mature: 34267

Theoretical pI: Translated: 7.48; Mature: 7.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSRHVIEREGILDPTRMTPRIPARPDDALSLEAEFGIASARKALDHAGVEPSQIDLIIC
CCCCCCCHHCCCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHCCCCCCEEEEEEE
SASHHQRPYPAIAIEMQEALGTTGAGFDMGLGCSSAAAALHMAVNLVRSGAHKRILVTTP
ECCCCCCCCCEEEEEEHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEECC
EIITGHLNFRDRQTHFIFGDASVSMVVEGLAQGDKRPGRFEVLDTRLWTQMSNNIRTNLG
HHEEEECCCCCCCEEEEEECCHHHHHHHHHHCCCCCCCCEEEEHHHHHHHHHCCCCCCCC
YHTRTAQDDPYMINLEGNLIKQVGNKVFKEVTVAGQKFIVEFLAEHGLTPQAIRRFWLHQ
CCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
ANARMNAMILKLSFGHDVDHDRAPMVLERLGNTAGAGAIVALSENHADMKPGDFGLICAF
CCCCEEEEEEEEECCCCCCCCCHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCEEEEEEE
GAGYSIGGALIRML
CCCCHHHHHHHHCC
>Mature Secondary Structure
MKSRHVIEREGILDPTRMTPRIPARPDDALSLEAEFGIASARKALDHAGVEPSQIDLIIC
CCCCCCCHHCCCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHCCCCCCEEEEEEE
SASHHQRPYPAIAIEMQEALGTTGAGFDMGLGCSSAAAALHMAVNLVRSGAHKRILVTTP
ECCCCCCCCCEEEEEEHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEECC
EIITGHLNFRDRQTHFIFGDASVSMVVEGLAQGDKRPGRFEVLDTRLWTQMSNNIRTNLG
HHEEEECCCCCCCEEEEEECCHHHHHHHHHHCCCCCCCCEEEEHHHHHHHHHCCCCCCCC
YHTRTAQDDPYMINLEGNLIKQVGNKVFKEVTVAGQKFIVEFLAEHGLTPQAIRRFWLHQ
CCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
ANARMNAMILKLSFGHDVDHDRAPMVLERLGNTAGAGAIVALSENHADMKPGDFGLICAF
CCCCEEEEEEEEECCCCCCCCCHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCEEEEEEE
GAGYSIGGALIRML
CCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14528314 [H]