Click here to switch to the map view.

The map label for this gene is slt [C]

Identifier: 13471559

GI number: 13471559

Start: 1306922

End: 1307776

Strand: Reverse

Name: slt [C]

Synonym: mll1569

Alternate gene names: 13471559

Gene position: 1307776-1306922 (Counterclockwise)

Preceding gene: 13471560

Following gene: 13471557

Centisome position: 18.59

GC content: 60.7

Gene sequence:

>855_bases
GTGACTTGCCCCGCCTTCATTGGCGCCAATTCGGGCCTCAAAGGGCAATTCGTACAGTTTGTCGGACCTCTAGCCCCCAG
ATGTTCCGATATTAATCAAGCCGCACCGCGCGAACATCTTCGCGTGGTCCAGACAGAACAGGATCACATGCAGAAATTGA
CCGTTGTAACGGCAGCTCTTGCTGCCGGCGTAATGACTTTTGCCTTCAGCGCGGCTGATGCCGCGCCGTTGAGCCCACGA
GCCGATGAAGGGCTCGTCGCGGCGACCGCCAAAGGCAAGGCCATTTCGGCCAAAAGCAGCAGGAGTGTGAAGGCGACGGC
GAAGCAGGCTTCCGCGAAGGTCGAAAAGGCCAGCTGGGCCAAGGCGAAGAAATCCTCCGCCAAAAGGCAGACGAAGCGTG
GCCGCAAGACCGTCGACATGACGACAACGGCATCGATCGGTCTCAGGAATGTCGCCGCGTCGACGGCAGCCGTGGCCAGC
AGCAGCCAGTATTCCGCGATCGTTGCCCGCTATGCGGCAAGCTACGGCGTTCCGGTGTCGCTGGCCAATGCCGTCATCAC
CATCGAGAGCAACTATCGGCCGAACATGGTCGGCAGTGCCGGCGAGATCGGCCTGATGCAGGTCAAGCCGGCGACGGCGC
GGATGATGGGCTACAACGGTTCGGCCAAGGGCCTGTTCGATCCCGACACCAACATCAAATACGGCATGAAGTATCTCGCT
TTGGCGCAGAACCTTGGCGGTGGCACGACCTGCGGCACGATCCTGAAATACAATGCCGGCCATGCCGCGACGCGGATGAA
CCCGGTCTCGGCCGCCTATTGCAGCAAGGTCAAGGTTCAGATGGCCGCCCTTTGA

Upstream 100 bases:

>100_bases
CACGCTGCAGAACTTGCTTGCCTCCGTGAGCGGCTGACGCGGCGGCAAGGTGTCGCCCAAGTAATCTTTTCCACTGCCAG
GTTACAAACTGTCACTCAAA

Downstream 100 bases:

>100_bases
TCGCAAGTTGCGAGAGCCGGCGGACAAGCCGGCTTTTTCATTTGCGTTTTCCCGGCTGAACCCCTTTATACGCCTTGCCA
GCTGGCTGGGCGGCCGCACT

Product: transglycosylase

Products: 1,6-Anhydrobond [C]

Alternate protein names: Transglycosylase; Transglycosylase Protein; Lytic Murein Transglycosylase; Soluble Lytic Transglycosylase; Transmembrane Protein; Transglycosylase SLT Domain Protein; Lytic Transglycosylase Catalytic Subunit; Soluble Lytic Murein Transglycosylase

Number of amino acids: Translated: 284; Mature: 283

Protein sequence:

>284_residues
MTCPAFIGANSGLKGQFVQFVGPLAPRCSDINQAAPREHLRVVQTEQDHMQKLTVVTAALAAGVMTFAFSAADAAPLSPR
ADEGLVAATAKGKAISAKSSRSVKATAKQASAKVEKASWAKAKKSSAKRQTKRGRKTVDMTTTASIGLRNVAASTAAVAS
SSQYSAIVARYAASYGVPVSLANAVITIESNYRPNMVGSAGEIGLMQVKPATARMMGYNGSAKGLFDPDTNIKYGMKYLA
LAQNLGGGTTCGTILKYNAGHAATRMNPVSAAYCSKVKVQMAAL

Sequences:

>Translated_284_residues
MTCPAFIGANSGLKGQFVQFVGPLAPRCSDINQAAPREHLRVVQTEQDHMQKLTVVTAALAAGVMTFAFSAADAAPLSPR
ADEGLVAATAKGKAISAKSSRSVKATAKQASAKVEKASWAKAKKSSAKRQTKRGRKTVDMTTTASIGLRNVAASTAAVAS
SSQYSAIVARYAASYGVPVSLANAVITIESNYRPNMVGSAGEIGLMQVKPATARMMGYNGSAKGLFDPDTNIKYGMKYLA
LAQNLGGGTTCGTILKYNAGHAATRMNPVSAAYCSKVKVQMAAL
>Mature_283_residues
TCPAFIGANSGLKGQFVQFVGPLAPRCSDINQAAPREHLRVVQTEQDHMQKLTVVTAALAAGVMTFAFSAADAAPLSPRA
DEGLVAATAKGKAISAKSSRSVKATAKQASAKVEKASWAKAKKSSAKRQTKRGRKTVDMTTTASIGLRNVAASTAAVASS
SQYSAIVARYAASYGVPVSLANAVITIESNYRPNMVGSAGEIGLMQVKPATARMMGYNGSAKGLFDPDTNIKYGMKYLAL
AQNLGGGTTCGTILKYNAGHAATRMNPVSAAYCSKVKVQMAAL

Specific function: Murein-Degrading Enzyme. Catalyzes The Cleavage Of The Glycosidic Bonds Between N-Acetylmuramic Acid And N- Acetylglucosamine Residues In Peptidoglycan. May Play A Role In Recycling Of Muropeptides During Cell Elongation And/Or Cell Division. [C]

COG id: COG0741

COG function: function code M; Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)

Gene ontology:

Cell location: Periplasmic Protein. Tightly Associated With The Murein Sacculus [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 3.2.1.- [C]

Molecular weight: Translated: 29459; Mature: 29328

Theoretical pI: Translated: 10.69; Mature: 10.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTCPAFIGANSGLKGQFVQFVGPLAPRCSDINQAAPREHLRVVQTEQDHMQKLTVVTAAL
CCCCCEECCCCCCCHHHHHHHCCCCCCCCCCCCCCCHHHHEECCCCHHHHHHHHHHHHHH
AAGVMTFAFSAADAAPLSPRADEGLVAATAKGKAISAKSSRSVKATAKQASAKVEKASWA
HHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCEECCCCCCCHHHHHHHHHHHHHHHHHH
KAKKSSAKRQTKRGRKTVDMTTTASIGLRNVAASTAAVASSSQYSAIVARYAASYGVPVS
HHHHHHHHHHHHCCCCEEEEEEHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEE
LANAVITIESNYRPNMVGSAGEIGLMQVKPATARMMGYNGSAKGLFDPDTNIKYGMKYLA
ECCEEEEEECCCCCCCCCCCCCEEEEEECCHHHHEECCCCCCCCCCCCCCCHHHHHHHHH
LAQNLGGGTTCGTILKYNAGHAATRMNPVSAAYCSKVKVQMAAL
HHHHCCCCCCCCCEEEECCCCCHHCCCCHHHHHHHHHEEEEECC
>Mature Secondary Structure 
TCPAFIGANSGLKGQFVQFVGPLAPRCSDINQAAPREHLRVVQTEQDHMQKLTVVTAAL
CCCCEECCCCCCCHHHHHHHCCCCCCCCCCCCCCCHHHHEECCCCHHHHHHHHHHHHHH
AAGVMTFAFSAADAAPLSPRADEGLVAATAKGKAISAKSSRSVKATAKQASAKVEKASWA
HHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCEECCCCCCCHHHHHHHHHHHHHHHHHH
KAKKSSAKRQTKRGRKTVDMTTTASIGLRNVAASTAAVASSSQYSAIVARYAASYGVPVS
HHHHHHHHHHHHCCCCEEEEEEHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEE
LANAVITIESNYRPNMVGSAGEIGLMQVKPATARMMGYNGSAKGLFDPDTNIKYGMKYLA
ECCEEEEEECCCCCCCCCCCCCEEEEEECCHHHHEECCCCCCCCCCCCCCCHHHHHHHHH
LAQNLGGGTTCGTILKYNAGHAATRMNPVSAAYCSKVKVQMAAL
HHHHCCCCCCCCCEEEECCCCCHHCCCCHHHHHHHHHEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Muramic Acid Residue (N-Acetylmuramic Acid And N-Acetylglucosamine Residues) [C]

Specific reaction: Cleavage Of The Beta-1,4-Glycosidic Bond Between N-Acetylmuramic Acid And N-Acetylglucosamine Residues, Thereby Conserving The Energy In A Newly Synthesized 1,6-Anhydrobond In The Muramic Acid Residue. [C]

General reaction: Cleavage Of The Beta-1,4-Glycosidic Bond [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA