Click here to switch to the map view.

The map label for this gene is mraW

Identifier: 13471557

GI number: 13471557

Start: 1303328

End: 1304344

Strand: Reverse

Name: mraW

Synonym: mll1565

Alternate gene names: 13471557

Gene position: 1304344-1303328 (Counterclockwise)

Preceding gene: 13471559

Following gene: 13471556

Centisome position: 18.54

GC content: 67.65

Gene sequence:

>1017_bases
ATGACGGTGGGCGACGGCGATGACATCCACGCCGTTGGCGGATCGGTCCGCCACATTCCGGTCCTCCTTGGCGAAGTGCT
CGAGGCACTGGCGCCGGCGGAGCGCGACATCATCATCGACGGCACGTTCGGCGCCGGCGGCTACACCAGGGCTATTCTGG
CGACCGGCGCTTCCGTCGTGGCGATCGACCGCGATCCCGATGCCATCGCCGCCGGCCGCGATCTCGAGGTACAATCGGGC
GGCAGGCTGAGACTGGTGCAGGCGCCGTTCTCGACGCTGGACGAACATGTCGAAAGCGCCGACGGCGTTGTGCTCGACAT
TGGCGTTTCCTCCATGCAGCTCGACCAGGCCGAGCGCGGCTTTTCCTTCCGTTTCGACGGGCCGCTCGACATGCGCATGG
CGCAGGCGGGCCTGAGTGCTGCCGATGTCGTCAACAGTTTCAAGCCGGGCGATCTTGCCCGCATCTTCGGCTTCCTCGGC
GAGGAGCGCCACGCCGGCCGCATCGCCCGCATGATCGAAGCGCGCCGCGAAAAGAAGCCGTTCGAGGGCACGTTGGAACT
GGCCGACGCCATCGAGACGCATATTGGCCGCGCGCCGAAGGACAAGATCCACCCGGCGACCCGCGTCTTCCAGGCGCTGC
GTATCTACGTCAATGACGAACTCGGCGAACTGGCCAAGGCGTTGTTCGCTGCCGAACGTGCATTGAAGCCCGGCGGACGC
CTGGTGGTGGTGACGTTCCATTCGCTGGAAGACCGCATCGTCAAGCGCTTCATCGCCGACCGCGCCGACGTCGCCACCGG
CTCACGTCATCTACCCGAGGCGCAGGCGCGCACGGCGACCTTCCGCAAGGCCGGCGGCGGCGTGACGGCGGGCGACGCCG
AGGTCGCTGCCAATCCGCGCGCCCGCTCGGCAAGGCTGCGCGCGGCGATCCGCACCGAGGCGCCGGCGCGCGCCGGTGAT
TTTTCGATTTTCGGCCTTCCAAAGCTTCCCGGCATCGATCGCCCGGGGGAGAGGTAA

Upstream 100 bases:

>100_bases
TTCAGATCTGGGAGCCGGGACGGCTTGCGGCCTATGGGGCGCAGGCGCGGGCCAGGCTTTTGCAGCTTCGGCAGGGGACG
AAGCCTGGGGAGCGACCGGA

Downstream 100 bases:

>100_bases
GCACGTGTTCCGTACCAGCGACATTGTCCTGATCGCCGTCATGGTTTCGGCGGCGGCCCTGACCTACAAGACCAAGCGCG
AGGCCGAGGACCAGTTGGCG

Product: S-adenosyl-methyltransferase MraW

Products: NA

Alternate protein names: 16S rRNA m(4)C1402 methyltransferase; rRNA (cytosine-N(4)-)-methyltransferase RsmH

Number of amino acids: Translated: 338; Mature: 337

Protein sequence:

>338_residues
MTVGDGDDIHAVGGSVRHIPVLLGEVLEALAPAERDIIIDGTFGAGGYTRAILATGASVVAIDRDPDAIAAGRDLEVQSG
GRLRLVQAPFSTLDEHVESADGVVLDIGVSSMQLDQAERGFSFRFDGPLDMRMAQAGLSAADVVNSFKPGDLARIFGFLG
EERHAGRIARMIEARREKKPFEGTLELADAIETHIGRAPKDKIHPATRVFQALRIYVNDELGELAKALFAAERALKPGGR
LVVVTFHSLEDRIVKRFIADRADVATGSRHLPEAQARTATFRKAGGGVTAGDAEVAANPRARSARLRAAIRTEAPARAGD
FSIFGLPKLPGIDRPGER

Sequences:

>Translated_338_residues
MTVGDGDDIHAVGGSVRHIPVLLGEVLEALAPAERDIIIDGTFGAGGYTRAILATGASVVAIDRDPDAIAAGRDLEVQSG
GRLRLVQAPFSTLDEHVESADGVVLDIGVSSMQLDQAERGFSFRFDGPLDMRMAQAGLSAADVVNSFKPGDLARIFGFLG
EERHAGRIARMIEARREKKPFEGTLELADAIETHIGRAPKDKIHPATRVFQALRIYVNDELGELAKALFAAERALKPGGR
LVVVTFHSLEDRIVKRFIADRADVATGSRHLPEAQARTATFRKAGGGVTAGDAEVAANPRARSARLRAAIRTEAPARAGD
FSIFGLPKLPGIDRPGER
>Mature_337_residues
TVGDGDDIHAVGGSVRHIPVLLGEVLEALAPAERDIIIDGTFGAGGYTRAILATGASVVAIDRDPDAIAAGRDLEVQSGG
RLRLVQAPFSTLDEHVESADGVVLDIGVSSMQLDQAERGFSFRFDGPLDMRMAQAGLSAADVVNSFKPGDLARIFGFLGE
ERHAGRIARMIEARREKKPFEGTLELADAIETHIGRAPKDKIHPATRVFQALRIYVNDELGELAKALFAAERALKPGGRL
VVVTFHSLEDRIVKRFIADRADVATGSRHLPEAQARTATFRKAGGGVTAGDAEVAANPRARSARLRAAIRTEAPARAGDF
SIFGLPKLPGIDRPGER

Specific function: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA

COG id: COG0275

COG function: function code M; Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmH family

Homologues:

Organism=Homo sapiens, GI165377209, Length=338, Percent_Identity=39.9408284023669, Blast_Score=207, Evalue=1e-53,
Organism=Homo sapiens, GI165377202, Length=187, Percent_Identity=42.2459893048128, Blast_Score=130, Evalue=2e-30,
Organism=Escherichia coli, GI1786270, Length=315, Percent_Identity=45.3968253968254, Blast_Score=223, Evalue=2e-59,
Organism=Drosophila melanogaster, GI62472493, Length=331, Percent_Identity=41.3897280966767, Blast_Score=196, Evalue=1e-50,
Organism=Drosophila melanogaster, GI28571637, Length=331, Percent_Identity=41.3897280966767, Blast_Score=196, Evalue=1e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RSMH_RHILO (Q98KA5)

Other databases:

- EMBL:   BA000012
- RefSeq:   NP_103123.1
- ProteinModelPortal:   Q98KA5
- SMR:   Q98KA5
- GeneID:   1225786
- GenomeReviews:   BA000012_GR
- KEGG:   mlo:mll1565
- NMPDR:   fig|266835.1.peg.1228
- HOGENOM:   HBG302779
- OMA:   PQLDDPE
- ProtClustDB:   PRK00050
- GO:   GO:0005737
- HAMAP:   MF_01007
- InterPro:   IPR002903
- PANTHER:   PTHR11265
- PIRSF:   PIRSF004486
- TIGRFAMs:   TIGR00006

Pfam domain/function: PF01795 Methyltransf_5

EC number: NA

Molecular weight: Translated: 36064; Mature: 35933

Theoretical pI: Translated: 6.74; Mature: 6.74

Prosite motif: NA

Important sites: BINDING 63-63 BINDING 90-90 BINDING 106-106 BINDING 113-113

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVGDGDDIHAVGGSVRHIPVLLGEVLEALAPAERDIIIDGTFGAGGYTRAILATGASVV
CCCCCCCCCHHCCCCHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHHHHCCCEEE
AIDRDPDAIAAGRDLEVQSGGRLRLVQAPFSTLDEHVESADGVVLDIGVSSMQLDQAERG
EEECCCCHHHCCCCEEECCCCCEEEEECCHHHHHHHHHHCCCEEEEECCCHHHHHHHHCC
FSFRFDGPLDMRMAQAGLSAADVVNSFKPGDLARIFGFLGEERHAGRIARMIEARREKKP
CEEEECCCHHHHHHHHCCCHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCC
FEGTLELADAIETHIGRAPKDKIHPATRVFQALRIYVNDELGELAKALFAAERALKPGGR
CCHHHHHHHHHHHHHCCCCCHHCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCC
LVVVTFHSLEDRIVKRFIADRADVATGSRHLPEAQARTATFRKAGGGVTAGDAEVAANPR
EEEEEECHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHCCCCC
ARSARLRAAIRTEAPARAGDFSIFGLPKLPGIDRPGER
HHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCCCC
>Mature Secondary Structure 
TVGDGDDIHAVGGSVRHIPVLLGEVLEALAPAERDIIIDGTFGAGGYTRAILATGASVV
CCCCCCCCHHCCCCHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHHHHCCCEEE
AIDRDPDAIAAGRDLEVQSGGRLRLVQAPFSTLDEHVESADGVVLDIGVSSMQLDQAERG
EEECCCCHHHCCCCEEECCCCCEEEEECCHHHHHHHHHHCCCEEEEECCCHHHHHHHHCC
FSFRFDGPLDMRMAQAGLSAADVVNSFKPGDLARIFGFLGEERHAGRIARMIEARREKKP
CEEEECCCHHHHHHHHCCCHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCC
FEGTLELADAIETHIGRAPKDKIHPATRVFQALRIYVNDELGELAKALFAAERALKPGGR
CCHHHHHHHHHHHHHCCCCCHHCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCC
LVVVTFHSLEDRIVKRFIADRADVATGSRHLPEAQARTATFRKAGGGVTAGDAEVAANPR
EEEEEECHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHCCCCC
ARSARLRAAIRTEAPARAGDFSIFGLPKLPGIDRPGER
HHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11214968