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The map label for this gene is ftsA [H]

Identifier: 13471544

GI number: 13471544

Start: 1287665

End: 1288972

Strand: Reverse

Name: ftsA [H]

Synonym: mll1549

Alternate gene names: 13471544

Gene position: 1288972-1287665 (Counterclockwise)

Preceding gene: 13471545

Following gene: 13471543

Centisome position: 18.32

GC content: 66.28

Gene sequence:

>1308_bases
ATGAGCTGGCTTGGCGGTTCAGGCGATGCCTCGTCGCGCCGGTCCGGCACTCTGACGGTGCTGGATGTCGGCTCGAACAA
GGTCTGCTGTATGGTGGCCAAGCTCAAGCCGAACGATGACGGCAAGCTGTTGCGCGGCCGTTCGCACCGGATCCAGGTGA
TCGGCATCGGTCATCAGAAGTCGCAAGGCGTGAAGTCGGGCGTGGTCGTCGATCTCGACCGGGCCGAGCATGCCATCCGC
CTGTCCGTCGACGCCGCCGAGCGCATGGCGGGGCTGACGGTCGATTCGCTCATCGTCAACATGACCGCCGGCCGGCTGAA
GAGCGAAGCCTTCTCGGCGACCATCAATCTTGGCGGCCACGAGGCCGACGAGGCCGACATCAAGCGTGTGCTCGGCGCCG
GCGCCAAGCAGGCGCTCAAGGCCGAGCGCGAGGTGATCCATTCGCTGCCCGTCGGCTTCTCGCTCGATGCCGAGCGCGGC
GTGCGCGATCCGCGCGGCATGGTCGGCGACGCGCTTGGCGTCGACATGCATGTGCTGACGGGTGACGCAGCGCCGATGCG
CAATCTGGAGCTTTCCATCAACCGTTCGCATCTGTCGGTCGAGCGCATGGTGGCGACGCCCTATGCCAGCGGGCTGGCGG
CTCTGGTCGACGACGAGTTGGAACTGGGTGCCGCCTGCATCGACATGGGCGGCGGCACGACGACGATCTCGGTGTTTTCG
GAAGGCAAGTTCGTTCATGGCGACGCCATCGCCATCGGCGGCAATCACGTCACGCTCGACATGGCCAAGGGGCTCTCGAC
CTCGCTCGACGCCGCCGAAAGGCTGAAGGTCATGCATGGCTCGGCGCTGCCGGGCAGTGCCGATGACCGCGACCTGGTCT
CGATCCAGCCGATCGGCGACGATGGCGACGTGCCGCTGCAGATCCCGCGTTCGGTGATGACGCGCATCGTGCGCGCCCGC
ATCGACGAGACGCTCGAATTGTTGCGCGACCGGCTGAACAAGTCCGGCTACGGCAATGCCGTCGGCAAGCGTGTCGTGCT
GACCGGCGGCGCCAGCCAGCTGGCCGGCCTGCCGGAAGCGGCGCGCCGCATCCTGGGGCGCAATGTGCGCATCGGCCGCC
CGCTCGGCGTGGCGGGCCTGCCCGAAGCGGCGAAGGGACCGGCCTTCTCGGCCGCCGTCGGGCTTCTGATCTATCCGCAG
ATGGCGAGTTTTGAGAGCCATCCTGCAAAAGGCATTTCCGGTCTCAGGATGACCGGAACGGGTGGAAAACTGCATCGCAT
GAGTCAGTGGTTGAGAGACAGTTTCTAA

Upstream 100 bases:

>100_bases
ACCGGCTGGTCGTGGAGCTGACGCCCGAAGCGGCGACGCAGCGCGAGGCCGCGCTCAACGAAAAGCCGAAGACCCTCAAG
CGCAAGTCGGAGACGAAGAT

Downstream 100 bases:

>100_bases
TTGACGGGGACAGCCCCATAGGCGGCCGCGGCGGCGAAGCGGCGTGAAAGGCAAAGGACGGAGACAATGACCATCAATCT
GCAGAAGCCGGACATCACCG

Product: cell division protein FtsA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 435; Mature: 434

Protein sequence:

>435_residues
MSWLGGSGDASSRRSGTLTVLDVGSNKVCCMVAKLKPNDDGKLLRGRSHRIQVIGIGHQKSQGVKSGVVVDLDRAEHAIR
LSVDAAERMAGLTVDSLIVNMTAGRLKSEAFSATINLGGHEADEADIKRVLGAGAKQALKAEREVIHSLPVGFSLDAERG
VRDPRGMVGDALGVDMHVLTGDAAPMRNLELSINRSHLSVERMVATPYASGLAALVDDELELGAACIDMGGGTTTISVFS
EGKFVHGDAIAIGGNHVTLDMAKGLSTSLDAAERLKVMHGSALPGSADDRDLVSIQPIGDDGDVPLQIPRSVMTRIVRAR
IDETLELLRDRLNKSGYGNAVGKRVVLTGGASQLAGLPEAARRILGRNVRIGRPLGVAGLPEAAKGPAFSAAVGLLIYPQ
MASFESHPAKGISGLRMTGTGGKLHRMSQWLRDSF

Sequences:

>Translated_435_residues
MSWLGGSGDASSRRSGTLTVLDVGSNKVCCMVAKLKPNDDGKLLRGRSHRIQVIGIGHQKSQGVKSGVVVDLDRAEHAIR
LSVDAAERMAGLTVDSLIVNMTAGRLKSEAFSATINLGGHEADEADIKRVLGAGAKQALKAEREVIHSLPVGFSLDAERG
VRDPRGMVGDALGVDMHVLTGDAAPMRNLELSINRSHLSVERMVATPYASGLAALVDDELELGAACIDMGGGTTTISVFS
EGKFVHGDAIAIGGNHVTLDMAKGLSTSLDAAERLKVMHGSALPGSADDRDLVSIQPIGDDGDVPLQIPRSVMTRIVRAR
IDETLELLRDRLNKSGYGNAVGKRVVLTGGASQLAGLPEAARRILGRNVRIGRPLGVAGLPEAAKGPAFSAAVGLLIYPQ
MASFESHPAKGISGLRMTGTGGKLHRMSQWLRDSF
>Mature_434_residues
SWLGGSGDASSRRSGTLTVLDVGSNKVCCMVAKLKPNDDGKLLRGRSHRIQVIGIGHQKSQGVKSGVVVDLDRAEHAIRL
SVDAAERMAGLTVDSLIVNMTAGRLKSEAFSATINLGGHEADEADIKRVLGAGAKQALKAEREVIHSLPVGFSLDAERGV
RDPRGMVGDALGVDMHVLTGDAAPMRNLELSINRSHLSVERMVATPYASGLAALVDDELELGAACIDMGGGTTTISVFSE
GKFVHGDAIAIGGNHVTLDMAKGLSTSLDAAERLKVMHGSALPGSADDRDLVSIQPIGDDGDVPLQIPRSVMTRIVRARI
DETLELLRDRLNKSGYGNAVGKRVVLTGGASQLAGLPEAARRILGRNVRIGRPLGVAGLPEAAKGPAFSAAVGLLIYPQM
ASFESHPAKGISGLRMTGTGGKLHRMSQWLRDSF

Specific function: This protein may be involved in anomalous filament growth. May be a component of the septum [H]

COG id: COG0849

COG function: function code D; Actin-like ATPase involved in cell division

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsA/mreB family [H]

Homologues:

Organism=Escherichia coli, GI1786282, Length=424, Percent_Identity=28.7735849056604, Blast_Score=199, Evalue=4e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020823
- InterPro:   IPR003494 [H]

Pfam domain/function: PF02491 FtsA [H]

EC number: NA

Molecular weight: Translated: 45673; Mature: 45542

Theoretical pI: Translated: 8.84; Mature: 8.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSWLGGSGDASSRRSGTLTVLDVGSNKVCCMVAKLKPNDDGKLLRGRSHRIQVIGIGHQK
CCCCCCCCCCCCCCCCCEEEEECCCCCEEEEEEEECCCCCCCEECCCCCEEEEEEECCCC
SQGVKSGVVVDLDRAEHAIRLSVDAAERMAGLTVDSLIVNMTAGRLKSEAFSATINLGGH
CCCCCCCEEEEECCCCCEEEEEECHHHHHHCCCHHHHHHHHHHHHHHHCCEEEEEECCCC
EADEADIKRVLGAGAKQALKAEREVIHSLPVGFSLDAERGVRDPRGMVGDALGVDMHVLT
CCCHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCHHCCCCCCCCCCCHHCCCEEEEEE
GDAAPMRNLELSINRSHLSVERMVATPYASGLAALVDDELELGAACIDMGGGTTTISVFS
CCCCCCCCEEEEEECCHHHHHHHHHCCHHCCHHHHHCCHHHHCEEEEECCCCEEEEEEEE
EGKFVHGDAIAIGGNHVTLDMAKGLSTSLDAAERLKVMHGSALPGSADDRDLVSIQPIGD
CCCEEECCEEEECCCEEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCC
DGDVPLQIPRSVMTRIVRARIDETLELLRDRLNKSGYGNAVGKRVVLTGGASQLAGLPEA
CCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCHHHHCCCHHH
ARRILGRNVRIGRPLGVAGLPEAAKGPAFSAAVGLLIYPQMASFESHPAKGISGLRMTGT
HHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHEEECCHHCCCCCCCCCCCCEEEECC
GGKLHRMSQWLRDSF
CCHHHHHHHHHHHCC
>Mature Secondary Structure 
SWLGGSGDASSRRSGTLTVLDVGSNKVCCMVAKLKPNDDGKLLRGRSHRIQVIGIGHQK
CCCCCCCCCCCCCCCCEEEEECCCCCEEEEEEEECCCCCCCEECCCCCEEEEEEECCCC
SQGVKSGVVVDLDRAEHAIRLSVDAAERMAGLTVDSLIVNMTAGRLKSEAFSATINLGGH
CCCCCCCEEEEECCCCCEEEEEECHHHHHHCCCHHHHHHHHHHHHHHHCCEEEEEECCCC
EADEADIKRVLGAGAKQALKAEREVIHSLPVGFSLDAERGVRDPRGMVGDALGVDMHVLT
CCCHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCHHCCCCCCCCCCCHHCCCEEEEEE
GDAAPMRNLELSINRSHLSVERMVATPYASGLAALVDDELELGAACIDMGGGTTTISVFS
CCCCCCCCEEEEEECCHHHHHHHHHCCHHCCHHHHHCCHHHHCEEEEECCCCEEEEEEEE
EGKFVHGDAIAIGGNHVTLDMAKGLSTSLDAAERLKVMHGSALPGSADDRDLVSIQPIGD
CCCEEECCEEEECCCEEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCC
DGDVPLQIPRSVMTRIVRARIDETLELLRDRLNKSGYGNAVGKRVVLTGGASQLAGLPEA
CCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCHHHHCCCHHH
ARRILGRNVRIGRPLGVAGLPEAAKGPAFSAAVGLLIYPQMASFESHPAKGISGLRMTGT
HHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHEEECCHHCCCCCCCCCCCCEEEECC
GGKLHRMSQWLRDSF
CCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9352931; 11481430 [H]