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The map label for this gene is putR [H]

Identifier: 13471244

GI number: 13471244

Start: 974341

End: 974802

Strand: Direct

Name: putR [H]

Synonym: mlr1161

Alternate gene names: 13471244

Gene position: 974341-974802 (Clockwise)

Preceding gene: 13471242

Following gene: 13471247

Centisome position: 13.85

GC content: 63.85

Gene sequence:

>462_bases
GTGATTTTGACAACAGAAGACCAATTGGACCGCATCGACCGCAACATCCTGTCGGCGCTGGCCAGCAATGGCCGGCTTTC
CATGTCGGAACTCGCGGCCAGGGTCGGCCTCTCCAAGACGCCGGTGCAGGCGCGCGTCAAGCGGCTGGAAAAGGACGGCT
ATATCAGGGGCTACCAGGCGATCATCGACCGCGAGCGCATGGGCGAAGGCCATGTCGCCTTCGTCCAGGTGAAATTGTCC
GACACGCGTTCCGCCGCGCTCGACGCTTTCAACCGGTCTGTGCAGGCCGTGCCGGAGATCGAGCAGTGCCACATGATGGC
GTCAAGCTTCGATTACCTGCTGAAGGTCCGCACCCGGGACATCGCCGCCTACCGCCGGGTGTTGGGCGAGCGCATCTCGG
CGCTGCCGCACGTCGCCCAGACCTCGACCTTCGTGGCGATGGAGACGGTGAAGGATCGCTGA

Upstream 100 bases:

>100_bases
TGGCGCAAGCTAGCACAGGCGCGGATTTCAGTCGGTCCAAAGAAATCGACAAGACAGATCGATCGATCTATCGTTATGTC
AACCCCTCTGAGTTTGGACT

Downstream 100 bases:

>100_bases
CCATGATCCCGAAAAGTGGATGCCGGTTTTCGGACAAGATCATGGTCAAACAAGAGCCTACTCCGTCAGCGTCCTCAAAA
ATGCCACCAGCGCTGCGCGC

Product: proline dehydrogenase transcriptional activator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 153; Mature: 153

Protein sequence:

>153_residues
MILTTEDQLDRIDRNILSALASNGRLSMSELAARVGLSKTPVQARVKRLEKDGYIRGYQAIIDRERMGEGHVAFVQVKLS
DTRSAALDAFNRSVQAVPEIEQCHMMASSFDYLLKVRTRDIAAYRRVLGERISALPHVAQTSTFVAMETVKDR

Sequences:

>Translated_153_residues
MILTTEDQLDRIDRNILSALASNGRLSMSELAARVGLSKTPVQARVKRLEKDGYIRGYQAIIDRERMGEGHVAFVQVKLS
DTRSAALDAFNRSVQAVPEIEQCHMMASSFDYLLKVRTRDIAAYRRVLGERISALPHVAQTSTFVAMETVKDR
>Mature_153_residues
MILTTEDQLDRIDRNILSALASNGRLSMSELAARVGLSKTPVQARVKRLEKDGYIRGYQAIIDRERMGEGHVAFVQVKLS
DTRSAALDAFNRSVQAVPEIEQCHMMASSFDYLLKVRTRDIAAYRRVLGERISALPHVAQTSTFVAMETVKDR

Specific function: Transcriptional activator of the putA gene in response to proline [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH asnC-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787116, Length=143, Percent_Identity=46.8531468531469, Blast_Score=144, Evalue=4e-36,
Organism=Escherichia coli, GI87081742, Length=143, Percent_Identity=34.965034965035, Blast_Score=94, Evalue=4e-21,
Organism=Escherichia coli, GI1790182, Length=143, Percent_Identity=24.4755244755245, Blast_Score=61, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011008
- InterPro:   IPR000485
- InterPro:   IPR019885
- InterPro:   IPR019888
- InterPro:   IPR019887
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01037 AsnC_trans_reg [H]

EC number: NA

Molecular weight: Translated: 17182; Mature: 17182

Theoretical pI: Translated: 9.85; Mature: 9.85

Prosite motif: PS00519 HTH_ASNC_1 ; PS50956 HTH_ASNC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILTTEDQLDRIDRNILSALASNGRLSMSELAARVGLSKTPVQARVKRLEKDGYIRGYQA
CCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHCCCHHHHHH
IIDRERMGEGHVAFVQVKLSDTRSAALDAFNRSVQAVPEIEQCHMMASSFDYLLKVRTRD
HHHHHHCCCCCEEEEEEEECCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
IAAYRRVLGERISALPHVAQTSTFVAMETVKDR
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MILTTEDQLDRIDRNILSALASNGRLSMSELAARVGLSKTPVQARVKRLEKDGYIRGYQA
CCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHCCCHHHHHH
IIDRERMGEGHVAFVQVKLSDTRSAALDAFNRSVQAVPEIEQCHMMASSFDYLLKVRTRD
HHHHHHCCCCCEEEEEEEECCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
IAAYRRVLGERISALPHVAQTSTFVAMETVKDR
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8606160 [H]