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The map label for this gene is argS

Identifier: 13471188

GI number: 13471188

Start: 914349

End: 916106

Strand: Reverse

Name: argS

Synonym: mll1091

Alternate gene names: 13471188

Gene position: 916106-914349 (Counterclockwise)

Preceding gene: 13471189

Following gene: 13471187

Centisome position: 13.02

GC content: 62.29

Gene sequence:

>1758_bases
ATGAACATCTTCGCCGATTTCACCGCGCGAGTCACAAAGGCTGTCGAAGCTCTTGATTTGAAAGACAAGGACGGCATTTC
GCCCGACCTGTCGCGCATTGCCGTCGAACCGCCGCGCGACGCCAGCCATGGTGACCTCGCGACCAATGCGGCGATGGTGC
TGGCCAAGCCCACCGGCCAGAACCCGCGCGCGCTGGCCGAGAAGCTGGCGTTGGCGCTGCGCGATGACAAGGATGTCGCC
GCCGCCGAGGTTGCCGGCCCGGGCTTCGTCAATCTGCGGCTCAAGGACGGCTTCTGGCAGGCACATCTGTCGGCGCTGCT
GGGCGATGGCCGCAATTACGGCCGCTCGACGGTCGGCGCCGGCCGGAAAACCAATGTCGAATATGTCTCGGCCAACCCGA
CGGGGCCGATGCATGTCGGCCATTGCCGGGGCGCCGTTGTCGGTGATGCGCTCGCCAATCTGATGGCCTTCGCCGGTTAC
GACGTGACCAAGGAATATGTCATCAACGATGCCGGCGGACAGATCGACGTGCTCGGCCGTTCTGTCATACTGCGGTACCG
GGAGGCGCTCGGCGACGAGATCGGCGAGATTCCGCCCGGCCTTTATCCCGGCGACTATCTGGTTCCTCTCGGCCAGGCGC
TGGCGAAGGAGTTCGGCCACGGCCTGCTCCAGATGCCGGAGGATGAGGCGCTGGCCATCGTCAAGGACCGTGCGATCGAC
GCGATGATGGCGATGATCCGCGATGATCTGGCGCTGCTCAACGTCCATCACGACGTGTTCTTCTCCGAGCGCACGCTGCA
TGCCGACAATGCCAGGAAGATCCGTTCGGCGATCAATGACCTGACGCTGAAGGGGCATATCTACAAGGGCAAGCTGCCGC
CGCCCAAGGGCGAGAAGCCGGACGATTGGGAAGATCGCGAGCAGACGTTGTTCCGCTCGACGGCGGTCGGCGACGATATG
GACCGGGCGCTGGTCAAGTCGGACGGGTCGTTCACCTATTTCGCCGCCGACGTGGCGTATCTGAAGGACAAGGTCGATCG
CGGCTTCGTCGACCTCATTTACGTGCTCGGCGCCGACCATGGCGGTTACGTCAAACGGCTGGAAGCGTTGGCGAGGGCAA
TCGCCGGCGACGAGGTGAAACTCACTGTCCTGTTGTGCAATCTGGTCAAGCTGTATCGTGACGGCGAGCCCATTCGCATG
TCGAAGCGGTCGGGCGATTTTGTCACGCTACGGGAAGTCGTGGAGGAGGTTGGCCGCGACGCCATCCGTTTCATGATGCT
GTACCGCAAGAGCGATGCGCCGCTCGATTTCGATTTCGCCAAGGTGACCGAACAGTCCAAGGACAATCCGGTGTTTTACG
TGCAGTACGCCTCGGCGCGCTGCCATTCGGTGTTCCGGCAGGCAAGCGAGCAATTGGGCGAGGCGAATTTCGATCGCAAG
AGCCTGGCTGCCGCCGCGGCTTCGCTGACCGACGAGGGCGAGATCGGCCTGATCCGCAAGCTCGCCGAATATCCCCGCCT
GATCGAGTCCGCCGCTCTTGCGCTGGAGCCGCATAGGCTGGCATTTTACCTCTATGATCTGGCTTCCAGTTTCCACGGAC
ACTGGAACCGGGGCACGGATAATCCGGACTTACGTTTTGTTAAGGTTAACGACCGACAATTGACGCATGCCAGACTAGGG
CTGGTGCAGGCTGTTTCGGACGTTCTGACGTCCGGCCTGACGCTGATCGGAGCCGCTGCGCCCACCGAAATGCGTTAG

Upstream 100 bases:

>100_bases
CACAGGCGTTTGTTTGACCGCACCCCGGATTTGAGCTAGGGCGAGCGCGATTTTGCCGGCCAACGAGCCGGATTCGCCTA
AAACCGCCAGAGCAATACCC

Downstream 100 bases:

>100_bases
GTTTGACTAAAAAACCTGTCACCTTTTGCCCACATTGCGCTGGTAAGGGCCAACCCTGCGCGACGTCCATGGCGTCCGAA
TGAGTGCGAGTTCGGGAACA

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS

Number of amino acids: Translated: 585; Mature: 585

Protein sequence:

>585_residues
MNIFADFTARVTKAVEALDLKDKDGISPDLSRIAVEPPRDASHGDLATNAAMVLAKPTGQNPRALAEKLALALRDDKDVA
AAEVAGPGFVNLRLKDGFWQAHLSALLGDGRNYGRSTVGAGRKTNVEYVSANPTGPMHVGHCRGAVVGDALANLMAFAGY
DVTKEYVINDAGGQIDVLGRSVILRYREALGDEIGEIPPGLYPGDYLVPLGQALAKEFGHGLLQMPEDEALAIVKDRAID
AMMAMIRDDLALLNVHHDVFFSERTLHADNARKIRSAINDLTLKGHIYKGKLPPPKGEKPDDWEDREQTLFRSTAVGDDM
DRALVKSDGSFTYFAADVAYLKDKVDRGFVDLIYVLGADHGGYVKRLEALARAIAGDEVKLTVLLCNLVKLYRDGEPIRM
SKRSGDFVTLREVVEEVGRDAIRFMMLYRKSDAPLDFDFAKVTEQSKDNPVFYVQYASARCHSVFRQASEQLGEANFDRK
SLAAAAASLTDEGEIGLIRKLAEYPRLIESAALALEPHRLAFYLYDLASSFHGHWNRGTDNPDLRFVKVNDRQLTHARLG
LVQAVSDVLTSGLTLIGAAAPTEMR

Sequences:

>Translated_585_residues
MNIFADFTARVTKAVEALDLKDKDGISPDLSRIAVEPPRDASHGDLATNAAMVLAKPTGQNPRALAEKLALALRDDKDVA
AAEVAGPGFVNLRLKDGFWQAHLSALLGDGRNYGRSTVGAGRKTNVEYVSANPTGPMHVGHCRGAVVGDALANLMAFAGY
DVTKEYVINDAGGQIDVLGRSVILRYREALGDEIGEIPPGLYPGDYLVPLGQALAKEFGHGLLQMPEDEALAIVKDRAID
AMMAMIRDDLALLNVHHDVFFSERTLHADNARKIRSAINDLTLKGHIYKGKLPPPKGEKPDDWEDREQTLFRSTAVGDDM
DRALVKSDGSFTYFAADVAYLKDKVDRGFVDLIYVLGADHGGYVKRLEALARAIAGDEVKLTVLLCNLVKLYRDGEPIRM
SKRSGDFVTLREVVEEVGRDAIRFMMLYRKSDAPLDFDFAKVTEQSKDNPVFYVQYASARCHSVFRQASEQLGEANFDRK
SLAAAAASLTDEGEIGLIRKLAEYPRLIESAALALEPHRLAFYLYDLASSFHGHWNRGTDNPDLRFVKVNDRQLTHARLG
LVQAVSDVLTSGLTLIGAAAPTEMR
>Mature_585_residues
MNIFADFTARVTKAVEALDLKDKDGISPDLSRIAVEPPRDASHGDLATNAAMVLAKPTGQNPRALAEKLALALRDDKDVA
AAEVAGPGFVNLRLKDGFWQAHLSALLGDGRNYGRSTVGAGRKTNVEYVSANPTGPMHVGHCRGAVVGDALANLMAFAGY
DVTKEYVINDAGGQIDVLGRSVILRYREALGDEIGEIPPGLYPGDYLVPLGQALAKEFGHGLLQMPEDEALAIVKDRAID
AMMAMIRDDLALLNVHHDVFFSERTLHADNARKIRSAINDLTLKGHIYKGKLPPPKGEKPDDWEDREQTLFRSTAVGDDM
DRALVKSDGSFTYFAADVAYLKDKVDRGFVDLIYVLGADHGGYVKRLEALARAIAGDEVKLTVLLCNLVKLYRDGEPIRM
SKRSGDFVTLREVVEEVGRDAIRFMMLYRKSDAPLDFDFAKVTEQSKDNPVFYVQYASARCHSVFRQASEQLGEANFDRK
SLAAAAASLTDEGEIGLIRKLAEYPRLIESAALALEPHRLAFYLYDLASSFHGHWNRGTDNPDLRFVKVNDRQLTHARLG
LVQAVSDVLTSGLTLIGAAAPTEMR

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI15149476, Length=610, Percent_Identity=25.4098360655738, Blast_Score=129, Evalue=5e-30,
Organism=Escherichia coli, GI1788184, Length=178, Percent_Identity=30.8988764044944, Blast_Score=78, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6320548, Length=616, Percent_Identity=24.3506493506494, Blast_Score=103, Evalue=5e-23,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYR_RHILO (Q98LC0)

Other databases:

- EMBL:   BA000012
- RefSeq:   NP_102757.1
- ProteinModelPortal:   Q98LC0
- GeneID:   1225420
- GenomeReviews:   BA000012_GR
- KEGG:   mlo:mll1091
- NMPDR:   fig|266835.1.peg.862
- HOGENOM:   HBG695395
- OMA:   FDVYFHE
- ProtClustDB:   PRK01611
- BRENDA:   6.1.1.19
- GO:   GO:0005737
- HAMAP:   MF_00123
- InterPro:   IPR001412
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080
- Gene3D:   G3DSA:3.30.1360.70
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR11956
- PRINTS:   PR01038
- SMART:   SM00836
- TIGRFAMs:   TIGR00456

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d; SSF55190 Arg-tRNA-synth_Ic_N; SSF47323 tRNAsyn_1a_bind

EC number: =6.1.1.19

Molecular weight: Translated: 64096; Mature: 64096

Theoretical pI: Translated: 6.02; Mature: 6.02

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIFADFTARVTKAVEALDLKDKDGISPDLSRIAVEPPRDASHGDLATNAAMVLAKPTGQ
CCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHEECCCCCCCCCCCCCCCCEEEEECCCCC
NPRALAEKLALALRDDKDVAAAEVAGPGFVNLRLKDGFWQAHLSALLGDGRNYGRSTVGA
CHHHHHHHHHHHHCCCCCHHHHHCCCCCEEEEEEECCHHHHHHHHHHHCCCCCCCHHCCC
GRKTNVEYVSANPTGPMHVGHCRGAVVGDALANLMAFAGYDVTKEYVINDAGGQIDVLGR
CCCCCEEEEECCCCCCCEECCCCCHHHHHHHHHHHHHHCCCCCHHHEEECCCCEEEHHHH
SVILRYREALGDEIGEIPPGLYPGDYLVPLGQALAKEFGHGLLQMPEDEALAIVKDRAID
HHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCEEHHHHHHHH
AMMAMIRDDLALLNVHHDVFFSERTLHADNARKIRSAINDLTLKGHIYKGKLPPPKGEKP
HHHHHHHHHHHHEEEHHHHHCCCCEECCCHHHHHHHHHHHCEEEEEEEECCCCCCCCCCC
DDWEDREQTLFRSTAVGDDMDRALVKSDGSFTYFAADVAYLKDKVDRGFVDLIYVLGADH
CCHHHHHHHHHHHHCCCCHHHHHHHHCCCCEEEEHHHHHHHHHHHCCCHHHHHHHHCCCC
GGYVKRLEALARAIAGDEVKLTVLLCNLVKLYRDGEPIRMSKRSGDFVTLREVVEEVGRD
CHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHCCCCCEEEECCCCCEEHHHHHHHHHHHH
AIRFMMLYRKSDAPLDFDFAKVTEQSKDNPVFYVQYASARCHSVFRQASEQLGEANFDRK
HHHHHHHHHCCCCCCCCHHHHHHHCCCCCCEEEEEECHHHHHHHHHHHHHHHCCCCCCHH
SLAAAAASLTDEGEIGLIRKLAEYPRLIESAALALEPHRLAFYLYDLASSFHGHWNRGTD
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCC
NPDLRFVKVNDRQLTHARLGLVQAVSDVLTSGLTLIGAAAPTEMR
CCCEEEEEECCCCHHHHHHHHHHHHHHHHHCCHHEEECCCCCCCC
>Mature Secondary Structure
MNIFADFTARVTKAVEALDLKDKDGISPDLSRIAVEPPRDASHGDLATNAAMVLAKPTGQ
CCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHEECCCCCCCCCCCCCCCCEEEEECCCCC
NPRALAEKLALALRDDKDVAAAEVAGPGFVNLRLKDGFWQAHLSALLGDGRNYGRSTVGA
CHHHHHHHHHHHHCCCCCHHHHHCCCCCEEEEEEECCHHHHHHHHHHHCCCCCCCHHCCC
GRKTNVEYVSANPTGPMHVGHCRGAVVGDALANLMAFAGYDVTKEYVINDAGGQIDVLGR
CCCCCEEEEECCCCCCCEECCCCCHHHHHHHHHHHHHHCCCCCHHHEEECCCCEEEHHHH
SVILRYREALGDEIGEIPPGLYPGDYLVPLGQALAKEFGHGLLQMPEDEALAIVKDRAID
HHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCEEHHHHHHHH
AMMAMIRDDLALLNVHHDVFFSERTLHADNARKIRSAINDLTLKGHIYKGKLPPPKGEKP
HHHHHHHHHHHHEEEHHHHHCCCCEECCCHHHHHHHHHHHCEEEEEEEECCCCCCCCCCC
DDWEDREQTLFRSTAVGDDMDRALVKSDGSFTYFAADVAYLKDKVDRGFVDLIYVLGADH
CCHHHHHHHHHHHHCCCCHHHHHHHHCCCCEEEEHHHHHHHHHHHCCCHHHHHHHHCCCC
GGYVKRLEALARAIAGDEVKLTVLLCNLVKLYRDGEPIRMSKRSGDFVTLREVVEEVGRD
CHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHCCCCCEEEECCCCCEEHHHHHHHHHHHH
AIRFMMLYRKSDAPLDFDFAKVTEQSKDNPVFYVQYASARCHSVFRQASEQLGEANFDRK
HHHHHHHHHCCCCCCCCHHHHHHHCCCCCCEEEEEECHHHHHHHHHHHHHHHCCCCCCHH
SLAAAAASLTDEGEIGLIRKLAEYPRLIESAALALEPHRLAFYLYDLASSFHGHWNRGTD
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCC
NPDLRFVKVNDRQLTHARLGLVQAVSDVLTSGLTLIGAAAPTEMR
CCCEEEEEECCCCHHHHHHHHHHHHHHHHHCCHHEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11214968