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The map label for this gene is glnII [H]

Identifier: 13470587

GI number: 13470587

Start: 236271

End: 237311

Strand: Direct

Name: glnII [H]

Synonym: mlr0339

Alternate gene names: 13470587

Gene position: 236271-237311 (Clockwise)

Preceding gene: 13470586

Following gene: 13470588

Centisome position: 3.36

GC content: 61.77

Gene sequence:

>1041_bases
ATGACGAAATACAAGCTCGAGTACATTTGGCTCGATGGTTACACCCCGGTCCCCAACCTTCGCGGCAAGACGCAGATCAA
GGAATTCGCCGAATTCCCGACGCTCGAACAGCTGCCGCTGTGGGGCTTCGACGGTTCCTCGACCATGCAGGCCGAAGGCC
GCAGCTCCGATTGCGTGTTGAAGCCGGTGGCGCTTTACCCGGATCCGGCCCGCACCAACGGCATTCTCGTCATGTGCGAG
GTCATGATGCCCGACGGCGTCACCCCGCATGAATCGAACAGCCGCGCGACCATCCTCGACGACGAGGACGCCTGGTTTGG
TTTCGAGCAAGAGTACTTCTTCTACAAGGACGGCCGCCCGCTCGGCTTCCCGGAGAGCGGTTATCCCGCGCCGCAGGGCC
CTTACTACACCGGCGTCGGCTACAAGAACGTCGGCGACGTCGCGCGCAAGATCGTCGAAGAGCATCTCGACCAGTGCCTC
GCGGCCGGCATCAACCATGAAGGCATCAACGCCGAAGTGGCCAAGGGCCAGTGGGAATTCCAGATTTTCGGCAAGGGCTC
CAAGAAGGCCGCCGACCAGATCTGGATGGCGCGCTACCTGCTCCTGCGTCTGACCGAGACTTACGGCATCGACATCGAGT
TCCACTGCAAGCCGCTCGGCGACACCGACTGGAACGGCTCGGGCATGCACTGCAATTTCTCGACCAAGTTCATGCGCGAA
GTCGGCGGCAAGGCCTATTTCGAAGCCCTGATGGCGCAGTTCGACAAAAACCTGATGGACCACATCGCCGTCTACGGGCC
GGACAACGACAAGCGCCTGACCGGCAAGCACGAGACCGCGCCGTGGAACAAGTTTAGCTATGGCGTCGCCGACCGTGGCG
CATCGATCCGCGTGCCGCACTCCTTCGTCAAGAATGACTACAAGGGCTATCTGGAAGACCGTCGTCCGAACTCCCAGGGC
GACCCCTACCAGATCGCTTCGCAGGTGCTGAAGACGATCTCGCAGGTTGCGACCGACGCGAAGGTCTCGGCCGCCGCCTG
A

Upstream 100 bases:

>100_bases
GCACACGAATTGCATTTTAGGGATCGGCAGCGCCGGCTGCCGACGGCAGACGTGTGTCGACGCCGTTTGGTGTTCGGTGA
ACAAGCAACGAGAGGCTAGA

Downstream 100 bases:

>100_bases
GTGTTTTCGCGGCGCGGATCGCAAGGTCCTCGCCGCGACCGAAACTCTGCAACGAAAAAGCCCTGGCGGAAACGCCAGGG
CTTTTTCGTATTTGCGAGGT

Product: glutamine synthetase II

Products: NA

Alternate protein names: Glutamate--ammonia ligase II; Glutamine synthetase II; GSII [H]

Number of amino acids: Translated: 346; Mature: 345

Protein sequence:

>346_residues
MTKYKLEYIWLDGYTPVPNLRGKTQIKEFAEFPTLEQLPLWGFDGSSTMQAEGRSSDCVLKPVALYPDPARTNGILVMCE
VMMPDGVTPHESNSRATILDDEDAWFGFEQEYFFYKDGRPLGFPESGYPAPQGPYYTGVGYKNVGDVARKIVEEHLDQCL
AAGINHEGINAEVAKGQWEFQIFGKGSKKAADQIWMARYLLLRLTETYGIDIEFHCKPLGDTDWNGSGMHCNFSTKFMRE
VGGKAYFEALMAQFDKNLMDHIAVYGPDNDKRLTGKHETAPWNKFSYGVADRGASIRVPHSFVKNDYKGYLEDRRPNSQG
DPYQIASQVLKTISQVATDAKVSAAA

Sequences:

>Translated_346_residues
MTKYKLEYIWLDGYTPVPNLRGKTQIKEFAEFPTLEQLPLWGFDGSSTMQAEGRSSDCVLKPVALYPDPARTNGILVMCE
VMMPDGVTPHESNSRATILDDEDAWFGFEQEYFFYKDGRPLGFPESGYPAPQGPYYTGVGYKNVGDVARKIVEEHLDQCL
AAGINHEGINAEVAKGQWEFQIFGKGSKKAADQIWMARYLLLRLTETYGIDIEFHCKPLGDTDWNGSGMHCNFSTKFMRE
VGGKAYFEALMAQFDKNLMDHIAVYGPDNDKRLTGKHETAPWNKFSYGVADRGASIRVPHSFVKNDYKGYLEDRRPNSQG
DPYQIASQVLKTISQVATDAKVSAAA
>Mature_345_residues
TKYKLEYIWLDGYTPVPNLRGKTQIKEFAEFPTLEQLPLWGFDGSSTMQAEGRSSDCVLKPVALYPDPARTNGILVMCEV
MMPDGVTPHESNSRATILDDEDAWFGFEQEYFFYKDGRPLGFPESGYPAPQGPYYTGVGYKNVGDVARKIVEEHLDQCLA
AGINHEGINAEVAKGQWEFQIFGKGSKKAADQIWMARYLLLRLTETYGIDIEFHCKPLGDTDWNGSGMHCNFSTKFMREV
GGKAYFEALMAQFDKNLMDHIAVYGPDNDKRLTGKHETAPWNKFSYGVADRGASIRVPHSFVKNDYKGYLEDRRPNSQGD
PYQIASQVLKTISQVATDAKVSAAA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutamine synthetase family [H]

Homologues:

Organism=Homo sapiens, GI74271826, Length=343, Percent_Identity=43.731778425656, Blast_Score=263, Evalue=2e-70,
Organism=Homo sapiens, GI74271837, Length=343, Percent_Identity=43.731778425656, Blast_Score=263, Evalue=2e-70,
Organism=Homo sapiens, GI19923206, Length=343, Percent_Identity=43.731778425656, Blast_Score=263, Evalue=2e-70,
Organism=Caenorhabditis elegans, GI115532978, Length=355, Percent_Identity=46.7605633802817, Blast_Score=286, Evalue=1e-77,
Organism=Caenorhabditis elegans, GI115532980, Length=355, Percent_Identity=46.7605633802817, Blast_Score=286, Evalue=2e-77,
Organism=Caenorhabditis elegans, GI17554028, Length=345, Percent_Identity=45.2173913043478, Blast_Score=275, Evalue=3e-74,
Organism=Caenorhabditis elegans, GI17540008, Length=346, Percent_Identity=45.0867052023121, Blast_Score=270, Evalue=6e-73,
Organism=Caenorhabditis elegans, GI17538856, Length=346, Percent_Identity=42.1965317919075, Blast_Score=259, Evalue=2e-69,
Organism=Caenorhabditis elegans, GI17551038, Length=318, Percent_Identity=40.8805031446541, Blast_Score=217, Evalue=6e-57,
Organism=Saccharomyces cerevisiae, GI6325292, Length=345, Percent_Identity=47.536231884058, Blast_Score=291, Evalue=1e-79,
Organism=Drosophila melanogaster, GI24641290, Length=338, Percent_Identity=48.5207100591716, Blast_Score=287, Evalue=6e-78,
Organism=Drosophila melanogaster, GI24641292, Length=338, Percent_Identity=48.5207100591716, Blast_Score=287, Evalue=6e-78,
Organism=Drosophila melanogaster, GI281360453, Length=345, Percent_Identity=45.2173913043478, Blast_Score=282, Evalue=2e-76,
Organism=Drosophila melanogaster, GI17136208, Length=345, Percent_Identity=45.2173913043478, Blast_Score=282, Evalue=2e-76,
Organism=Drosophila melanogaster, GI24580558, Length=345, Percent_Identity=45.2173913043478, Blast_Score=282, Evalue=2e-76,
Organism=Drosophila melanogaster, GI45554830, Length=268, Percent_Identity=48.8805970149254, Blast_Score=234, Evalue=6e-62,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008147
- InterPro:   IPR014746
- InterPro:   IPR008146 [H]

Pfam domain/function: PF00120 Gln-synt_C; PF03951 Gln-synt_N [H]

EC number: =6.3.1.2 [H]

Molecular weight: Translated: 38841; Mature: 38710

Theoretical pI: Translated: 5.44; Mature: 5.44

Prosite motif: PS00180 GLNA_1 ; PS00181 GLNA_ATP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKYKLEYIWLDGYTPVPNLRGKTQIKEFAEFPTLEQLPLWGFDGSSTMQAEGRSSDCVL
CCEEEEEEEEECCCCCCCCCCCHHHHHHHHHCCCHHHCEEECCCCCCEEECCCCCCCEEE
KPVALYPDPARTNGILVMCEVMMPDGVTPHESNSRATILDDEDAWFGFEQEYFFYKDGRP
EEEEECCCCCCCCCEEEEEEEECCCCCCCCCCCCEEEEECCCCCCCCCCCCEEEEECCCC
LGFPESGYPAPQGPYYTGVGYKNVGDVARKIVEEHLDQCLAAGINHEGINAEVAKGQWEF
CCCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCEEEE
QIFGKGSKKAADQIWMARYLLLRLTETYGIDIEFHCKPLGDTDWNGSGMHCNFSTKFMRE
EEEECCCHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCCCCCCCCEEECCHHHHHHH
VGGKAYFEALMAQFDKNLMDHIAVYGPDNDKRLTGKHETAPWNKFSYGVADRGASIRVPH
HCCHHHHHHHHHHHHHHHHHHEEEECCCCCCEECCCCCCCCCCCEECCCCCCCCEEECCH
SFVKNDYKGYLEDRRPNSQGDPYQIASQVLKTISQVATDAKVSAAA
HHHHCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHCCCC
>Mature Secondary Structure 
TKYKLEYIWLDGYTPVPNLRGKTQIKEFAEFPTLEQLPLWGFDGSSTMQAEGRSSDCVL
CEEEEEEEEECCCCCCCCCCCHHHHHHHHHCCCHHHCEEECCCCCCEEECCCCCCCEEE
KPVALYPDPARTNGILVMCEVMMPDGVTPHESNSRATILDDEDAWFGFEQEYFFYKDGRP
EEEEECCCCCCCCCEEEEEEEECCCCCCCCCCCCEEEEECCCCCCCCCCCCEEEEECCCC
LGFPESGYPAPQGPYYTGVGYKNVGDVARKIVEEHLDQCLAAGINHEGINAEVAKGQWEF
CCCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCEEEE
QIFGKGSKKAADQIWMARYLLLRLTETYGIDIEFHCKPLGDTDWNGSGMHCNFSTKFMRE
EEEECCCHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCCCCCCCCEEECCHHHHHHH
VGGKAYFEALMAQFDKNLMDHIAVYGPDNDKRLTGKHETAPWNKFSYGVADRGASIRVPH
HCCHHHHHHHHHHHHHHHHHHEEEECCCCCCEECCCCCCCCCCCEECCCCCCCCEEECCH
SFVKNDYKGYLEDRRPNSQGDPYQIASQVLKTISQVATDAKVSAAA
HHHHCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12597275 [H]