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The map label for this gene is rpoB [H]

Identifier: 13470542

GI number: 13470542

Start: 193431

End: 197567

Strand: Direct

Name: rpoB [H]

Synonym: mlr0276

Alternate gene names: 13470542

Gene position: 193431-197567 (Clockwise)

Preceding gene: 13470541

Following gene: 13470543

Centisome position: 2.75

GC content: 62.75

Gene sequence:

>4137_bases
ATGGCCCAGACCCAGACTTTCAATGGCCGCAGACGCGTACGCAAGTTCTTCGGAAAGATTCCGGAAGTTGCGGAGATGCC
GAACCTGATCGAGGTTCAGAAGGCATCCTATGACCAGTTCCTGATGGTGGACGAGCCCAAGGGCGGCCGTCCGGACGAGG
GACTGCAGGCTGTTTTCAAGTCGGTCTTCCCGATCTCCGATTTTTCCGGCTCCTCGATGCTGGAGTTCGTGAAGTACGAG
TTCGAAGGACCGAAATTCGACGTTGACGAATGCCGTCAGCGCGACCTGACCTATGCCGCGCCGCTGAAGGTGACGCTGCG
CCTCATCGTGTTCGATATCGACGAGGATACCGGCGCCAAGTCGATCAAGGACATCAAGGAGCAGGACGTCTACATGGGCG
ACATGCCGCTCATGACCTTGAACGGCACCTTCATCGTCAACGGCACCGAGCGCGTCATCGTCTCGCAGATGCACCGTTCG
CCGGGCGTCTTCTTCGACCACGACAAAGGCAAGTCGCACTCGTCGGGCAAGCTTCTGTTTGCCGCGCGCGTCATTCCCTA
TCGCGGCTCGTGGCTCGACATCGAGTTCGATTCCAAGGACGTCGTGCACGCCCGCATCGACCGCCGCCGCAAGATTCCGG
TGACGTCGCTGTTGATGGCGCTCGGCATGGATGGCGAAGAGATCCTGTCGACCTTCTACAACAAGATCACCTATGTGCGC
GCCGGCGACCACTGGCGTATTCCGTTCAACGTCGAGCGTTTCCGCGGCCTCAAGGCCGTCGGCGACCTGGTCGATGCCGA
TACGGGCGAGATCGTTGTCGAGGCCGGCAAGAAGATCACCGCCCGTCAGGCGCGCCAGCTCGGTGAGAAGGGCCTGAAGG
CGATCAAGGCGACCGACGAGGATCTGCTCGGCAACTACCTGGCCGAGGACATCGTCAATTACGCCACCGGCGAGATCTTC
CTTGAAGCCGGCGACGAGATCGACGAGAAGACCCTGAAGGTGCTGCTTGGCACCGGCGAGCAGGAGATCAAGGTTCTCGA
CATCGACCACGTCAATGTCGGCGCCTATATCCGCAACACGCTCAACGTCGACAAGAACGAGAGCCGCCAGGACGCGCTGT
TCGACATCTATCGTGTCATGCGCCCGGGCGAGCCGCCGACGCTCGAGACCGCCGAAGCCATGTTCAACTCGCTGTTCTTC
GACTCAGAGCGCTATGACCTGTCGGCTGTCGGCCGCGTCAAGATGAACATGCGCCTCGAGCTCAAGGCCGAGGACACCGT
GCGCGTGCTGCGCAAGGAAGACATCCTGGCCGTGGTCAAGACGCTGGTCGAACTGCGCGACGGCAAGGGCGAGATCGACG
ACATCGACAATCTCGGCAACCGCCGCGTGCGTTCCGTCGGCGAGTTGATGGAGAACCAGTACCGCGTCGGCCTGTTGCGC
ATGGAGCGCGCGATCAAGGAGCGTATGTCCTCGATCGAGATCGACACGGTGATGCCGCAGGACCTGATCAACGCCAAGCC
GGCGGCCGCCGCCGTGCGCGAGTTCTTCGGTTCCTCGCAGCTGTCGCAGTTCATGGACCAGACCAACCCGCTGTCGGAGA
TCACCCACAAGCGCCGCCTGTCGGCGCTTGGACCAGGCGGTCTGACCCGCGAGCGCGCCGGCTTCGAAGTGCGCGACGTG
CACCCGACGCATTACGGCCGTATCTGCCCGATCGAGACGCCGGAAGGCCCGAATATCGGTCTGATCAACTCGCTGGCCAC
CTTCGCGCGCGTCAACAAGTACGGCTTTATCGAGAGCCCGTACCGCAAGATCGTCGATGGCAAGCTGACCAATGACGTCG
TCTATCTCTCGGCGATGGAAGAAGCCAAGCACCATGTCGCGCAGGCCAACGCCGAGCTCGACAAGAATGGCGGCTTCGTC
GACGAGTTCGTCATTTGCCGCAGTGCCGGCGAAGTGATGATGGCGCCGCGCGAGAATGTCGACCTGATGGACGTGTCGCC
CAAGCAGATGGTGTCGGTGGCCGCGGCCCTGATCCCGTTCCTGGAAAACGACGACGCCAACCGTGCGCTGATGGGCTCGA
ACATGCAGCGTCAGGCCGTGCCGCTGGTGCGCGCCGAGGCGCCGTTTGTCGGCACCGGCATGGAGCCGATCGTTGCCCGT
GACTCCGGCGCCGCCATCGGCGCCCGCCGCGGCGGCATCGTCGACCAGGTGGACGCGACGCGTATCGTTATCCGCGCGAC
GGAAGATCTCGATCCGGGCAAGTCCGGCGTCGACATCTACCGGCTGATGAAGTTCCAGCGTTCGAACCAGAACACCTGCA
TCAACCAGCGTCCGCTGGTGCGCATGGGTGACCGGGTCAACAAGGGCGACATCATCGCCGACGGTCCGTCGACCGAGCTC
GGTGATTTGGCGCTCGGCCGCAACGTGCTGGTCGCGTTCATGCCGTGGAACGGCTACAACTACGAGGACTCGATCCTGCT
CTCCGAGCGCATCGTCGCCGACGACGTCTTCACCTCGATCCACATCGAGGAGTTCGAGGTCATGGCGCGCGATACCAAGC
TTGGTCCGGAGGAAATCACCCGCGACATTCCGAACGTTTCGGAAGAAGCGCTGAAGAACCTCGACGAAGCCGGCATCGTC
TATATCGGCGCGGAAGTGCAGCCGGGCGACATCCTGGTCGGCAAGATCACGCCGAAGGGCGAGAGCCCGATGACGCCGGA
AGAAAAGCTTCTGCGCGCCATCTTCGGTGAAAAGGCTTCCGACGTGCGCGACACTTCGATGCGCATGCCTCCGGGTACTT
TCGGCACCGTCGTCGAGGTGCGCGTGTTCAATCGCCACGGTGTGGAGAAGGACGAGCGCGCCATGGCGATCGAGCGCGAG
GAGATCGAACGCCTCGCCAAGGACCGCGACGACGAGCAGGCCATTTTGGACCGCAACGTCTACGCGCGTCTTTCCGACGT
GCTCGTCGGCAAGGAAGCGATCGCTGGACCGAAGGGCTTCAAGAAGGGCTCGACGCTGTCCAAGGACACGCTCGACGAGT
ATCCGCGTTCGCAGTGGTGGCAGTTTGCCGTGGAGAATGAAAAGCTCCAGAGCGAACTGGAAGCCCTGCGTGGCCAGTAC
GACGACTCCAAGAAGGCGCTCGAACAGCGCTTCATGGACAAGGTCGAGAAGGTGCAGCGCGGCGACGAAATGCCTCCGGG
CGTCATGAAGATGGTCAAGGTCTTCGTGGCGGTGAAGCGCAAGATGCAGCCGGGCGACAAGATGGCCGGCCGTCACGGCA
ACAAGGGTGTCGTGTCGCGCATCGTTCCGGTCGAGGACATGCCTTTCCTCGAGGACGGCACGCATGCCGATATCGTGCTC
AACCCGCTGGGTGTGCCGAGCCGCATGAATGTCGGGCAGATCCTGGAAACGCATCTGGGCTGGGCCTGCGCGGGCATGGG
CAAGAAGATCGGCGAGCTGATCGACACCTACAAGGCGGCGGGCGACATCAAGCCGCTGCGCAAGACGCTGGAAAGCTTCA
TGCCGGCCAATGACCGCAACGAGCCGATCCGCGAGTATGACGACGAGAGCATTGTTCGCCTCAGCGAGCAGATGCGCCGC
GGCGTCTCGATCGCGACCCCGGTGTTCGACGGTGCGCACGAGGCTGACATCAACATCATGCTGGAGCAGGCGGGCCTGCA
CACCAGCGGTCAGTCGCAGCTCTATGACGGACGCACGGGCGAGCCGTTCGATCGCAAGGTGACGATGGGCTATATCTACA
TGCTCAAGCTTCACCACCTGGTGGACGACAAGATCCACGCGCGTTCGATCGGTCCGTACTCGCTCGTCACCCAGCAGCCG
CTGGGCGGCAAGGCGCAGTTCGGTGGCCAGCGCTTCGGCGAAATGGAGGTCTGGGCGCTGGAAGCCTACGGCGCCGCCTA
CACGCTGCAGGAAATGCTGACGGTGAAGTCGGACGACGTCGCCGGCCGCACCAAGGTCTACGAGGCGATCGTGCGCGGCG
ACGACACGTTCGAGGCCGGGATTCCGGAGAGCTTCAACGTGCTCGTCAAGGAAATGCGGTCTCTCGGCCTCAATGTCGAG
CTGGAGAACACCAAGCTCGACGACGCCCCTGTCCGGCTGCCCGACGCGGCCGAGTAA

Upstream 100 bases:

>100_bases
AGGCGAACGGAGAACAGACAGAGAGCCGCCGCCCAGGTGGCTCGGTATGCAAGGCGGACCGCGGCGAGGTCCGCCCCGAG
TTTAGAGCTAAGGAGCGACG

Downstream 100 bases:

>100_bases
AGGCTACAGCGCGCCGCACGAAGTTGCGGCGCGCAAAGGAATTCGACGGCCGGTGGCCGACAAAAGATGGCGGGCGTTTG
GCCCGCGACTAGATGCAAGG

Product: DNA-directed RNA polymerase subunit beta

Products: NA

Alternate protein names: RNAP subunit beta; RNA polymerase subunit beta; Transcriptase subunit beta [H]

Number of amino acids: Translated: 1378; Mature: 1377

Protein sequence:

>1378_residues
MAQTQTFNGRRRVRKFFGKIPEVAEMPNLIEVQKASYDQFLMVDEPKGGRPDEGLQAVFKSVFPISDFSGSSMLEFVKYE
FEGPKFDVDECRQRDLTYAAPLKVTLRLIVFDIDEDTGAKSIKDIKEQDVYMGDMPLMTLNGTFIVNGTERVIVSQMHRS
PGVFFDHDKGKSHSSGKLLFAARVIPYRGSWLDIEFDSKDVVHARIDRRRKIPVTSLLMALGMDGEEILSTFYNKITYVR
AGDHWRIPFNVERFRGLKAVGDLVDADTGEIVVEAGKKITARQARQLGEKGLKAIKATDEDLLGNYLAEDIVNYATGEIF
LEAGDEIDEKTLKVLLGTGEQEIKVLDIDHVNVGAYIRNTLNVDKNESRQDALFDIYRVMRPGEPPTLETAEAMFNSLFF
DSERYDLSAVGRVKMNMRLELKAEDTVRVLRKEDILAVVKTLVELRDGKGEIDDIDNLGNRRVRSVGELMENQYRVGLLR
MERAIKERMSSIEIDTVMPQDLINAKPAAAAVREFFGSSQLSQFMDQTNPLSEITHKRRLSALGPGGLTRERAGFEVRDV
HPTHYGRICPIETPEGPNIGLINSLATFARVNKYGFIESPYRKIVDGKLTNDVVYLSAMEEAKHHVAQANAELDKNGGFV
DEFVICRSAGEVMMAPRENVDLMDVSPKQMVSVAAALIPFLENDDANRALMGSNMQRQAVPLVRAEAPFVGTGMEPIVAR
DSGAAIGARRGGIVDQVDATRIVIRATEDLDPGKSGVDIYRLMKFQRSNQNTCINQRPLVRMGDRVNKGDIIADGPSTEL
GDLALGRNVLVAFMPWNGYNYEDSILLSERIVADDVFTSIHIEEFEVMARDTKLGPEEITRDIPNVSEEALKNLDEAGIV
YIGAEVQPGDILVGKITPKGESPMTPEEKLLRAIFGEKASDVRDTSMRMPPGTFGTVVEVRVFNRHGVEKDERAMAIERE
EIERLAKDRDDEQAILDRNVYARLSDVLVGKEAIAGPKGFKKGSTLSKDTLDEYPRSQWWQFAVENEKLQSELEALRGQY
DDSKKALEQRFMDKVEKVQRGDEMPPGVMKMVKVFVAVKRKMQPGDKMAGRHGNKGVVSRIVPVEDMPFLEDGTHADIVL
NPLGVPSRMNVGQILETHLGWACAGMGKKIGELIDTYKAAGDIKPLRKTLESFMPANDRNEPIREYDDESIVRLSEQMRR
GVSIATPVFDGAHEADINIMLEQAGLHTSGQSQLYDGRTGEPFDRKVTMGYIYMLKLHHLVDDKIHARSIGPYSLVTQQP
LGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVAGRTKVYEAIVRGDDTFEAGIPESFNVLVKEMRSLGLNVE
LENTKLDDAPVRLPDAAE

Sequences:

>Translated_1378_residues
MAQTQTFNGRRRVRKFFGKIPEVAEMPNLIEVQKASYDQFLMVDEPKGGRPDEGLQAVFKSVFPISDFSGSSMLEFVKYE
FEGPKFDVDECRQRDLTYAAPLKVTLRLIVFDIDEDTGAKSIKDIKEQDVYMGDMPLMTLNGTFIVNGTERVIVSQMHRS
PGVFFDHDKGKSHSSGKLLFAARVIPYRGSWLDIEFDSKDVVHARIDRRRKIPVTSLLMALGMDGEEILSTFYNKITYVR
AGDHWRIPFNVERFRGLKAVGDLVDADTGEIVVEAGKKITARQARQLGEKGLKAIKATDEDLLGNYLAEDIVNYATGEIF
LEAGDEIDEKTLKVLLGTGEQEIKVLDIDHVNVGAYIRNTLNVDKNESRQDALFDIYRVMRPGEPPTLETAEAMFNSLFF
DSERYDLSAVGRVKMNMRLELKAEDTVRVLRKEDILAVVKTLVELRDGKGEIDDIDNLGNRRVRSVGELMENQYRVGLLR
MERAIKERMSSIEIDTVMPQDLINAKPAAAAVREFFGSSQLSQFMDQTNPLSEITHKRRLSALGPGGLTRERAGFEVRDV
HPTHYGRICPIETPEGPNIGLINSLATFARVNKYGFIESPYRKIVDGKLTNDVVYLSAMEEAKHHVAQANAELDKNGGFV
DEFVICRSAGEVMMAPRENVDLMDVSPKQMVSVAAALIPFLENDDANRALMGSNMQRQAVPLVRAEAPFVGTGMEPIVAR
DSGAAIGARRGGIVDQVDATRIVIRATEDLDPGKSGVDIYRLMKFQRSNQNTCINQRPLVRMGDRVNKGDIIADGPSTEL
GDLALGRNVLVAFMPWNGYNYEDSILLSERIVADDVFTSIHIEEFEVMARDTKLGPEEITRDIPNVSEEALKNLDEAGIV
YIGAEVQPGDILVGKITPKGESPMTPEEKLLRAIFGEKASDVRDTSMRMPPGTFGTVVEVRVFNRHGVEKDERAMAIERE
EIERLAKDRDDEQAILDRNVYARLSDVLVGKEAIAGPKGFKKGSTLSKDTLDEYPRSQWWQFAVENEKLQSELEALRGQY
DDSKKALEQRFMDKVEKVQRGDEMPPGVMKMVKVFVAVKRKMQPGDKMAGRHGNKGVVSRIVPVEDMPFLEDGTHADIVL
NPLGVPSRMNVGQILETHLGWACAGMGKKIGELIDTYKAAGDIKPLRKTLESFMPANDRNEPIREYDDESIVRLSEQMRR
GVSIATPVFDGAHEADINIMLEQAGLHTSGQSQLYDGRTGEPFDRKVTMGYIYMLKLHHLVDDKIHARSIGPYSLVTQQP
LGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVAGRTKVYEAIVRGDDTFEAGIPESFNVLVKEMRSLGLNVE
LENTKLDDAPVRLPDAAE
>Mature_1377_residues
AQTQTFNGRRRVRKFFGKIPEVAEMPNLIEVQKASYDQFLMVDEPKGGRPDEGLQAVFKSVFPISDFSGSSMLEFVKYEF
EGPKFDVDECRQRDLTYAAPLKVTLRLIVFDIDEDTGAKSIKDIKEQDVYMGDMPLMTLNGTFIVNGTERVIVSQMHRSP
GVFFDHDKGKSHSSGKLLFAARVIPYRGSWLDIEFDSKDVVHARIDRRRKIPVTSLLMALGMDGEEILSTFYNKITYVRA
GDHWRIPFNVERFRGLKAVGDLVDADTGEIVVEAGKKITARQARQLGEKGLKAIKATDEDLLGNYLAEDIVNYATGEIFL
EAGDEIDEKTLKVLLGTGEQEIKVLDIDHVNVGAYIRNTLNVDKNESRQDALFDIYRVMRPGEPPTLETAEAMFNSLFFD
SERYDLSAVGRVKMNMRLELKAEDTVRVLRKEDILAVVKTLVELRDGKGEIDDIDNLGNRRVRSVGELMENQYRVGLLRM
ERAIKERMSSIEIDTVMPQDLINAKPAAAAVREFFGSSQLSQFMDQTNPLSEITHKRRLSALGPGGLTRERAGFEVRDVH
PTHYGRICPIETPEGPNIGLINSLATFARVNKYGFIESPYRKIVDGKLTNDVVYLSAMEEAKHHVAQANAELDKNGGFVD
EFVICRSAGEVMMAPRENVDLMDVSPKQMVSVAAALIPFLENDDANRALMGSNMQRQAVPLVRAEAPFVGTGMEPIVARD
SGAAIGARRGGIVDQVDATRIVIRATEDLDPGKSGVDIYRLMKFQRSNQNTCINQRPLVRMGDRVNKGDIIADGPSTELG
DLALGRNVLVAFMPWNGYNYEDSILLSERIVADDVFTSIHIEEFEVMARDTKLGPEEITRDIPNVSEEALKNLDEAGIVY
IGAEVQPGDILVGKITPKGESPMTPEEKLLRAIFGEKASDVRDTSMRMPPGTFGTVVEVRVFNRHGVEKDERAMAIEREE
IERLAKDRDDEQAILDRNVYARLSDVLVGKEAIAGPKGFKKGSTLSKDTLDEYPRSQWWQFAVENEKLQSELEALRGQYD
DSKKALEQRFMDKVEKVQRGDEMPPGVMKMVKVFVAVKRKMQPGDKMAGRHGNKGVVSRIVPVEDMPFLEDGTHADIVLN
PLGVPSRMNVGQILETHLGWACAGMGKKIGELIDTYKAAGDIKPLRKTLESFMPANDRNEPIREYDDESIVRLSEQMRRG
VSIATPVFDGAHEADINIMLEQAGLHTSGQSQLYDGRTGEPFDRKVTMGYIYMLKLHHLVDDKIHARSIGPYSLVTQQPL
GGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVAGRTKVYEAIVRGDDTFEAGIPESFNVLVKEMRSLGLNVEL
ENTKLDDAPVRLPDAAE

Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates [H]

COG id: COG0085

COG function: function code K; DNA-directed RNA polymerase, beta subunit/140 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA polymerase beta chain family [H]

Homologues:

Organism=Homo sapiens, GI4505941, Length=249, Percent_Identity=32.9317269076305, Blast_Score=126, Evalue=2e-28,
Organism=Homo sapiens, GI238908505, Length=308, Percent_Identity=29.2207792207792, Blast_Score=125, Evalue=2e-28,
Organism=Homo sapiens, GI238908503, Length=308, Percent_Identity=29.2207792207792, Blast_Score=125, Evalue=2e-28,
Organism=Homo sapiens, GI33469941, Length=322, Percent_Identity=27.9503105590062, Blast_Score=124, Evalue=7e-28,
Organism=Homo sapiens, GI212286172, Length=322, Percent_Identity=27.9503105590062, Blast_Score=123, Evalue=1e-27,
Organism=Escherichia coli, GI1790419, Length=1365, Percent_Identity=58.2417582417582, Blast_Score=1618, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17552304, Length=309, Percent_Identity=29.4498381877023, Blast_Score=125, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI25144348, Length=297, Percent_Identity=29.96632996633, Blast_Score=122, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI17506623, Length=238, Percent_Identity=31.9327731092437, Blast_Score=120, Evalue=7e-27,
Organism=Saccharomyces cerevisiae, GI6324781, Length=297, Percent_Identity=31.6498316498317, Blast_Score=131, Evalue=7e-31,
Organism=Saccharomyces cerevisiae, GI6324725, Length=310, Percent_Identity=29.0322580645161, Blast_Score=125, Evalue=6e-29,
Organism=Saccharomyces cerevisiae, GI6325267, Length=250, Percent_Identity=32.4, Blast_Score=124, Evalue=1e-28,
Organism=Drosophila melanogaster, GI17136444, Length=249, Percent_Identity=32.5301204819277, Blast_Score=126, Evalue=1e-28,
Organism=Drosophila melanogaster, GI17136446, Length=320, Percent_Identity=30, Blast_Score=115, Evalue=2e-25,
Organism=Drosophila melanogaster, GI17647877, Length=110, Percent_Identity=40.9090909090909, Blast_Score=90, Evalue=1e-17,

Paralogues:

None

Copy number: 4233 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010243
- InterPro:   IPR019462
- InterPro:   IPR015712
- InterPro:   IPR007120
- InterPro:   IPR007121
- InterPro:   IPR007644
- InterPro:   IPR007642
- InterPro:   IPR007645
- InterPro:   IPR007641
- InterPro:   IPR014724 [H]

Pfam domain/function: PF04563 RNA_pol_Rpb2_1; PF04561 RNA_pol_Rpb2_2; PF04565 RNA_pol_Rpb2_3; PF10385 RNA_pol_Rpb2_45; PF00562 RNA_pol_Rpb2_6; PF04560 RNA_pol_Rpb2_7 [H]

EC number: =2.7.7.6 [H]

Molecular weight: Translated: 153904; Mature: 153772

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: PS01166 RNA_POL_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQTQTFNGRRRVRKFFGKIPEVAEMPNLIEVQKASYDQFLMVDEPKGGRPDEGLQAVFK
CCCCCCCCHHHHHHHHHHCCCCHHHCCCHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHH
SVFPISDFSGSSMLEFVKYEFEGPKFDVDECRQRDLTYAAPLKVTLRLIVFDIDEDTGAK
HHCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHCCCCEECCCEEEEEEEEEEECCCCCHH
SIKDIKEQDVYMGDMPLMTLNGTFIVNGTERVIVSQMHRSPGVFFDHDKGKSHSSGKLLF
HHHHHHHHCCEECCCCEEEECCEEEECCCHHHHHHHHHCCCCCEEECCCCCCCCCCCEEE
AARVIPYRGSWLDIEFDSKDVVHARIDRRRKIPVTSLLMALGMDGEEILSTFYNKITYVR
EEEEECCCCCEEEEEECCCCHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHEEEEE
AGDHWRIPFNVERFRGLKAVGDLVDADTGEIVVEAGKKITARQARQLGEKGLKAIKATDE
CCCEEECCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHCCCH
DLLGNYLAEDIVNYATGEIFLEAGDEIDEKTLKVLLGTGEQEIKVLDIDHVNVGAYIRNT
HHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHH
LNVDKNESRQDALFDIYRVMRPGEPPTLETAEAMFNSLFFDSERYDLSAVGRVKMNMRLE
CCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCHHEECEEEEEEEEE
LKAEDTVRVLRKEDILAVVKTLVELRDGKGEIDDIDNLGNRRVRSVGELMENQYRVGLLR
ECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHH
MERAIKERMSSIEIDTVMPQDLINAKPAAAAVREFFGSSQLSQFMDQTNPLSEITHKRRL
HHHHHHHHHHCCEEHHCCCHHHHCCCHHHHHHHHHHCHHHHHHHHHCCCCHHHHHHHHHH
SALGPGGLTRERAGFEVRDVHPTHYGRICPIETPEGPNIGLINSLATFARVNKYGFIESP
HHCCCCCCCHHHCCCEEEECCCCCCCCEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCCH
YRKIVDGKLTNDVVYLSAMEEAKHHVAQANAELDKNGGFVDEFVICRSAGEVMMAPRENV
HHHHHCCCCCCCEEEEHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCEEECCCCCC
DLMDVSPKQMVSVAAALIPFLENDDANRALMGSNMQRQAVPLVRAEAPFVGTGMEPIVAR
CEEECCHHHHHHHHHHHHHHHCCCCCCCHHHCCCCHHHCCCEEECCCCCCCCCCCCEEEC
DSGAAIGARRGGIVDQVDATRIVIRATEDLDPGKSGVDIYRLMKFQRSNQNTCINQRPLV
CCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHH
RMGDRVNKGDIIADGPSTELGDLALGRNVLVAFMPWNGYNYEDSILLSERIVADDVFTSI
HHCCCCCCCCEEECCCCCCHHHHHCCCCEEEEEECCCCCCCCCCEEHHHHHHHHHHHHHH
HIEEFEVMARDTKLGPEEITRDIPNVSEEALKNLDEAGIVYIGAEVQPGDILVGKITPKG
HHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHCCCCCCEEEEECCCCCCCEEEEEECCCC
ESPMTPEEKLLRAIFGEKASDVRDTSMRMPPGTFGTVVEVRVFNRHGVEKDERAMAIERE
CCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHH
EIERLAKDRDDEQAILDRNVYARLSDVLVGKEAIAGPKGFKKGSTLSKDTLDEYPRSQWW
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCCHHHHH
QFAVENEKLQSELEALRGQYDDSKKALEQRFMDKVEKVQRGDEMPPGVMKMVKVFVAVKR
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
KMQPGDKMAGRHGNKGVVSRIVPVEDMPFLEDGTHADIVLNPLGVPSRMNVGQILETHLG
HCCCCHHHCCCCCCCCHHHEECCCCCCCCCCCCCCCEEEECCCCCCCCCCHHHHHHHHHC
WACAGMGKKIGELIDTYKAAGDIKPLRKTLESFMPANDRNEPIREYDDESIVRLSEQMRR
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCHHHCCCHHHHHHHHHHHC
GVSIATPVFDGAHEADINIMLEQAGLHTSGQSQLYDGRTGEPFDRKVTMGYIYMLKLHHL
CCEEECCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
VDDKIHARSIGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDV
HCCCHHHCCCCCHHHEECCCCCCCCCCCCCCCCCEEEEEEEHHCHHHHHHHHHHHCCCCC
AGRTKVYEAIVRGDDTFEAGIPESFNVLVKEMRSLGLNVELENTKLDDAPVRLPDAAE
CHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
AQTQTFNGRRRVRKFFGKIPEVAEMPNLIEVQKASYDQFLMVDEPKGGRPDEGLQAVFK
CCCCCCCHHHHHHHHHHCCCCHHHCCCHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHH
SVFPISDFSGSSMLEFVKYEFEGPKFDVDECRQRDLTYAAPLKVTLRLIVFDIDEDTGAK
HHCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHCCCCEECCCEEEEEEEEEEECCCCCHH
SIKDIKEQDVYMGDMPLMTLNGTFIVNGTERVIVSQMHRSPGVFFDHDKGKSHSSGKLLF
HHHHHHHHCCEECCCCEEEECCEEEECCCHHHHHHHHHCCCCCEEECCCCCCCCCCCEEE
AARVIPYRGSWLDIEFDSKDVVHARIDRRRKIPVTSLLMALGMDGEEILSTFYNKITYVR
EEEEECCCCCEEEEEECCCCHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHEEEEE
AGDHWRIPFNVERFRGLKAVGDLVDADTGEIVVEAGKKITARQARQLGEKGLKAIKATDE
CCCEEECCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHCCCH
DLLGNYLAEDIVNYATGEIFLEAGDEIDEKTLKVLLGTGEQEIKVLDIDHVNVGAYIRNT
HHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHH
LNVDKNESRQDALFDIYRVMRPGEPPTLETAEAMFNSLFFDSERYDLSAVGRVKMNMRLE
CCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCHHEECEEEEEEEEE
LKAEDTVRVLRKEDILAVVKTLVELRDGKGEIDDIDNLGNRRVRSVGELMENQYRVGLLR
ECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHH
MERAIKERMSSIEIDTVMPQDLINAKPAAAAVREFFGSSQLSQFMDQTNPLSEITHKRRL
HHHHHHHHHHCCEEHHCCCHHHHCCCHHHHHHHHHHCHHHHHHHHHCCCCHHHHHHHHHH
SALGPGGLTRERAGFEVRDVHPTHYGRICPIETPEGPNIGLINSLATFARVNKYGFIESP
HHCCCCCCCHHHCCCEEEECCCCCCCCEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCCH
YRKIVDGKLTNDVVYLSAMEEAKHHVAQANAELDKNGGFVDEFVICRSAGEVMMAPRENV
HHHHHCCCCCCCEEEEHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCEEECCCCCC
DLMDVSPKQMVSVAAALIPFLENDDANRALMGSNMQRQAVPLVRAEAPFVGTGMEPIVAR
CEEECCHHHHHHHHHHHHHHHCCCCCCCHHHCCCCHHHCCCEEECCCCCCCCCCCCEEEC
DSGAAIGARRGGIVDQVDATRIVIRATEDLDPGKSGVDIYRLMKFQRSNQNTCINQRPLV
CCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHH
RMGDRVNKGDIIADGPSTELGDLALGRNVLVAFMPWNGYNYEDSILLSERIVADDVFTSI
HHCCCCCCCCEEECCCCCCHHHHHCCCCEEEEEECCCCCCCCCCEEHHHHHHHHHHHHHH
HIEEFEVMARDTKLGPEEITRDIPNVSEEALKNLDEAGIVYIGAEVQPGDILVGKITPKG
HHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHCCCCCCEEEEECCCCCCCEEEEEECCCC
ESPMTPEEKLLRAIFGEKASDVRDTSMRMPPGTFGTVVEVRVFNRHGVEKDERAMAIERE
CCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHH
EIERLAKDRDDEQAILDRNVYARLSDVLVGKEAIAGPKGFKKGSTLSKDTLDEYPRSQWW
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCCHHHHH
QFAVENEKLQSELEALRGQYDDSKKALEQRFMDKVEKVQRGDEMPPGVMKMVKVFVAVKR
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
KMQPGDKMAGRHGNKGVVSRIVPVEDMPFLEDGTHADIVLNPLGVPSRMNVGQILETHLG
HCCCCHHHCCCCCCCCHHHEECCCCCCCCCCCCCCCEEEECCCCCCCCCCHHHHHHHHHC
WACAGMGKKIGELIDTYKAAGDIKPLRKTLESFMPANDRNEPIREYDDESIVRLSEQMRR
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCHHHCCCHHHHHHHHHHHC
GVSIATPVFDGAHEADINIMLEQAGLHTSGQSQLYDGRTGEPFDRKVTMGYIYMLKLHHL
CCEEECCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
VDDKIHARSIGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDV
HCCCHHHCCCCCHHHEECCCCCCCCCCCCCCCCCEEEEEEEHHCHHHHHHHHHHHCCCCC
AGRTKVYEAIVRGDDTFEAGIPESFNVLVKEMRSLGLNVELENTKLDDAPVRLPDAAE
CHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA