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The map label for this gene is ppiD [H]

Identifier: 15603844

GI number: 15603844

Start: 2216438

End: 2218318

Strand: Direct

Name: ppiD [H]

Synonym: PM1979

Alternate gene names: 15603844

Gene position: 2216438-2218318 (Clockwise)

Preceding gene: 15603843

Following gene: 161723302

Centisome position: 98.18

GC content: 41.04

Gene sequence:

>1881_bases
ATGTTAATTGAAAAACTTCACGGCATGACCAACAGTTGGGTATCCAAATTTTTGTTAGGTCTGATTGCTGTGGCTTTTGT
GTTAAGCGGGATTACAGGTTACGTTTTTACGCGCGTAGATACTTCAGCGGTAAAAATCAATGGTGAAGAAATTTCACAAC
AAACCTTTTATCAACGTTATGAATCAGAGTCAGAGCGTTTAAGACAGCAACTCGGTGCACAATTTGCTGCTTTATCGGGC
TCGCCTGAGTTTGTGGCTGGTTTAAGACAAAGTGTGCTAAATAATTTAATTAACCAAGAATTATTACGCCAGTATGCTGA
TGAGTTGAAAATAGGTATTAGCGATGAACGTGTTAAACAAGAAATTGTGACAAGTCAATTTTTCCAACAAGAAGGAAAAT
TTGATAATGCCCTGTATCAGCGCATGTTGCAATTAAATGGCTTAACGCCAGATGCCTACGCCAATATTGTGCGTGAGGGG
TTACGTTTAGAGCAGCTGCAAACGGGATTAGCGGAAAGTGAATTTATTGTTCCTGCACAACAAGCGCAATTAACGGAATT
GTTCTTTCAAGCAAGAACAGTACGTTTAGCGCCATTTTCGCTCGATCAAGTGTTAGAAAAGCAAACCATTTCCGATGAAG
AGGTTAGTGCGTATTATGAAGCAAATAAAGGGGCGTTTTTAGTACCAGAATTGGCTAAAGTGCAATACATGACATTAACA
CGTGCTGATGTCGAAAAACATATTCAAGTGTCAGATGTAGAAATTGCACAATATTATCAAGATAATAAAGCCCTTTATGT
GTCCCAAGGTCAGCAACGCTTATCGCATATTCAAGTGGCAACGGAAGCGGAAGCCAAAGAGATTTATCAAGCATTGCAAG
ATGGCGCTAATTTTGCTGGTTTAGCGAGCGCGCGTTCACTCGATAAAATTTCTGCTGAAAATGGTGGTGATTTGAGTTGG
GCCAGTGCAGGGACGTTCCCAAAAGCTTTTGAAGAGGCAGCTAACGCGCTTCAAGTGGGGCAATTCAGTCAACCGGTGAA
AGTAGATGATCAGTTCCATATTATTTTGGTCACAGAGCGTAAAGAACCATCAACTTTACCATTAGAGGTTGTGAAAACCC
AGATTGCAGATCAAATTCGTCAGAATTTAGTCAATAATCAGTATTTCTCGATTGAAAAACAACTGGCAGAAAAAGCGTTT
GAACACCCAGAAGGATTAGAAAAAGCTGCTGAAGTGGCGGGATTAACCATTCAAGAGACAGACTTTTTCTCAGCAAATGA
TGTGCCTGCGGCGTTAAATTATCCAAATGTGATTTCGGCGATCTTCCATTCTGATATCTCACAAGGGGGCGTGAACTCTG
AGCCGATGAATGTGGGCGAACAACATGCTGTGCTCGTGCGTGTTATTGCAAACAAACCCGAAGGTACAAGAAGCTTAGAG
GAAGCAAAAGCCGATATTATCAGCTACTTGAAGCGCCAAAAAGCAGAAGAAATTGTATTGGCAGAAGCAAACCAAGCGGC
ACAGCGTTTAAATGACAATGCAAGCTCAACGTTACCAGAAGGCGTTCAGTTTGGCTCAGCGGAGAAATGGGTTTTTGCTG
AAAATCGCGATGCGGCATTAAATAATGTGATTTTTGCCATGTCATTAACGGATAATAAACCGAGCTATATCGCATCGAAA
GCAAGCAATGGCGAGGTGGTTTTAGTGGAATTAAGTCATATTGAGCAAGGTGCATTAAGTGCAGCAGAAAGTGAATTATT
CACAAAACAGCTTGCACAAGCCCGTCAAGTTGCGTTGCAAAATACTTTATTACAAGCTTTACGAGCGAAAGCGAAAATTG
AAGTGAATGAAAAGTTCTTCCAGCAAAATGAAGAGCAATAA

Upstream 100 bases:

>100_bases
TATGATTTGGCTTATTTTATTTTGCCAGTGCGAAAATCAGTACTTTTGATTATAATCGTACACATTTTCGGTTGATTTAA
ATACGTATAGGATAATAACA

Downstream 100 bases:

>100_bases
GACGTAAAACTTGTGACATGAGAGCCTAGCGAATTTGCTAGGCTTTTTTTCGTATCAGGAAAGTAGAAGGCATTATTGCG
ATTGCCAACCAACGCCGATA

Product: hypothetical protein

Products: NA

Alternate protein names: PPIase D; Rotamase D [H]

Number of amino acids: Translated: 626; Mature: 626

Protein sequence:

>626_residues
MLIEKLHGMTNSWVSKFLLGLIAVAFVLSGITGYVFTRVDTSAVKINGEEISQQTFYQRYESESERLRQQLGAQFAALSG
SPEFVAGLRQSVLNNLINQELLRQYADELKIGISDERVKQEIVTSQFFQQEGKFDNALYQRMLQLNGLTPDAYANIVREG
LRLEQLQTGLAESEFIVPAQQAQLTELFFQARTVRLAPFSLDQVLEKQTISDEEVSAYYEANKGAFLVPELAKVQYMTLT
RADVEKHIQVSDVEIAQYYQDNKALYVSQGQQRLSHIQVATEAEAKEIYQALQDGANFAGLASARSLDKISAENGGDLSW
ASAGTFPKAFEEAANALQVGQFSQPVKVDDQFHIILVTERKEPSTLPLEVVKTQIADQIRQNLVNNQYFSIEKQLAEKAF
EHPEGLEKAAEVAGLTIQETDFFSANDVPAALNYPNVISAIFHSDISQGGVNSEPMNVGEQHAVLVRVIANKPEGTRSLE
EAKADIISYLKRQKAEEIVLAEANQAAQRLNDNASSTLPEGVQFGSAEKWVFAENRDAALNNVIFAMSLTDNKPSYIASK
ASNGEVVLVELSHIEQGALSAAESELFTKQLAQARQVALQNTLLQALRAKAKIEVNEKFFQQNEEQ

Sequences:

>Translated_626_residues
MLIEKLHGMTNSWVSKFLLGLIAVAFVLSGITGYVFTRVDTSAVKINGEEISQQTFYQRYESESERLRQQLGAQFAALSG
SPEFVAGLRQSVLNNLINQELLRQYADELKIGISDERVKQEIVTSQFFQQEGKFDNALYQRMLQLNGLTPDAYANIVREG
LRLEQLQTGLAESEFIVPAQQAQLTELFFQARTVRLAPFSLDQVLEKQTISDEEVSAYYEANKGAFLVPELAKVQYMTLT
RADVEKHIQVSDVEIAQYYQDNKALYVSQGQQRLSHIQVATEAEAKEIYQALQDGANFAGLASARSLDKISAENGGDLSW
ASAGTFPKAFEEAANALQVGQFSQPVKVDDQFHIILVTERKEPSTLPLEVVKTQIADQIRQNLVNNQYFSIEKQLAEKAF
EHPEGLEKAAEVAGLTIQETDFFSANDVPAALNYPNVISAIFHSDISQGGVNSEPMNVGEQHAVLVRVIANKPEGTRSLE
EAKADIISYLKRQKAEEIVLAEANQAAQRLNDNASSTLPEGVQFGSAEKWVFAENRDAALNNVIFAMSLTDNKPSYIASK
ASNGEVVLVELSHIEQGALSAAESELFTKQLAQARQVALQNTLLQALRAKAKIEVNEKFFQQNEEQ
>Mature_626_residues
MLIEKLHGMTNSWVSKFLLGLIAVAFVLSGITGYVFTRVDTSAVKINGEEISQQTFYQRYESESERLRQQLGAQFAALSG
SPEFVAGLRQSVLNNLINQELLRQYADELKIGISDERVKQEIVTSQFFQQEGKFDNALYQRMLQLNGLTPDAYANIVREG
LRLEQLQTGLAESEFIVPAQQAQLTELFFQARTVRLAPFSLDQVLEKQTISDEEVSAYYEANKGAFLVPELAKVQYMTLT
RADVEKHIQVSDVEIAQYYQDNKALYVSQGQQRLSHIQVATEAEAKEIYQALQDGANFAGLASARSLDKISAENGGDLSW
ASAGTFPKAFEEAANALQVGQFSQPVKVDDQFHIILVTERKEPSTLPLEVVKTQIADQIRQNLVNNQYFSIEKQLAEKAF
EHPEGLEKAAEVAGLTIQETDFFSANDVPAALNYPNVISAIFHSDISQGGVNSEPMNVGEQHAVLVRVIANKPEGTRSLE
EAKADIISYLKRQKAEEIVLAEANQAAQRLNDNASSTLPEGVQFGSAEKWVFAENRDAALNNVIFAMSLTDNKPSYIASK
ASNGEVVLVELSHIEQGALSAAESELFTKQLAQARQVALQNTLLQALRAKAKIEVNEKFFQQNEEQ

Specific function: PPIases accelerate the folding of proteins. Seems to be involved in the folding of outer membrane proteins [H]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein; Periplasmic side (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

Organism=Escherichia coli, GI1786645, Length=628, Percent_Identity=32.3248407643312, Blast_Score=333, Evalue=3e-92,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 69442; Mature: 69442

Theoretical pI: Translated: 4.55; Mature: 4.55

Prosite motif: PS01096 PPIC_PPIASE_1 ; PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIEKLHGMTNSWVSKFLLGLIAVAFVLSGITGYVFTRVDTSAVKINGEEISQQTFYQRY
CCHHHHCCCHHHHHHHHHHHHHHHHHHHHCHHHHEEEEECCCEEEECHHHHHHHHHHHHH
ESESERLRQQLGAQFAALSGSPEFVAGLRQSVLNNLINQELLRQYADELKIGISDERVKQ
HHHHHHHHHHHCCHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
EIVTSQFFQQEGKFDNALYQRMLQLNGLTPDAYANIVREGLRLEQLQTGLAESEFIVPAQ
HHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEECCHH
QAQLTELFFQARTVRLAPFSLDQVLEKQTISDEEVSAYYEANKGAFLVPELAKVQYMTLT
HHHHHHHHHHHHHEEECCCCHHHHHHHHCCCHHHHHHHHCCCCCCEECCHHHHHHHHHHH
RADVEKHIQVSDVEIAQYYQDNKALYVSQGQQRLSHIQVATEAEAKEIYQALQDGANFAG
HHHHHHCCCCCHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
LASARSLDKISAENGGDLSWASAGTFPKAFEEAANALQVGQFSQPVKVDDQFHIILVTER
HHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECC
KEPSTLPLEVVKTQIADQIRQNLVNNQYFSIEKQLAEKAFEHPEGLEKAAEVAGLTIQET
CCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCEEECC
DFFSANDVPAALNYPNVISAIFHSDISQGGVNSEPMNVGEQHAVLVRVIANKPEGTRSLE
CCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHH
EAKADIISYLKRQKAEEIVLAEANQAAQRLNDNASSTLPEGVQFGSAEKWVFAENRDAAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEECCCCCHH
NNVIFAMSLTDNKPSYIASKASNGEVVLVELSHIEQGALSAAESELFTKQLAQARQVALQ
CCEEEEEEECCCCCCCEEECCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
NTLLQALRAKAKIEVNEKFFQQNEEQ
HHHHHHHHHHHHEEECHHHHCCCCCC
>Mature Secondary Structure
MLIEKLHGMTNSWVSKFLLGLIAVAFVLSGITGYVFTRVDTSAVKINGEEISQQTFYQRY
CCHHHHCCCHHHHHHHHHHHHHHHHHHHHCHHHHEEEEECCCEEEECHHHHHHHHHHHHH
ESESERLRQQLGAQFAALSGSPEFVAGLRQSVLNNLINQELLRQYADELKIGISDERVKQ
HHHHHHHHHHHCCHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
EIVTSQFFQQEGKFDNALYQRMLQLNGLTPDAYANIVREGLRLEQLQTGLAESEFIVPAQ
HHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEECCHH
QAQLTELFFQARTVRLAPFSLDQVLEKQTISDEEVSAYYEANKGAFLVPELAKVQYMTLT
HHHHHHHHHHHHHEEECCCCHHHHHHHHCCCHHHHHHHHCCCCCCEECCHHHHHHHHHHH
RADVEKHIQVSDVEIAQYYQDNKALYVSQGQQRLSHIQVATEAEAKEIYQALQDGANFAG
HHHHHHCCCCCHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
LASARSLDKISAENGGDLSWASAGTFPKAFEEAANALQVGQFSQPVKVDDQFHIILVTER
HHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECC
KEPSTLPLEVVKTQIADQIRQNLVNNQYFSIEKQLAEKAFEHPEGLEKAAEVAGLTIQET
CCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCEEECC
DFFSANDVPAALNYPNVISAIFHSDISQGGVNSEPMNVGEQHAVLVRVIANKPEGTRSLE
CCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHH
EAKADIISYLKRQKAEEIVLAEANQAAQRLNDNASSTLPEGVQFGSAEKWVFAENRDAAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEECCCCCHH
NNVIFAMSLTDNKPSYIASKASNGEVVLVELSHIEQGALSAAESELFTKQLAQARQVALQ
CCEEEEEEECCCCCCCEEECCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
NTLLQALRAKAKIEVNEKFFQQNEEQ
HHHHHHHHHHHHEEECHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]