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The map label for this gene is dcuB [H]

Identifier: 15603783

GI number: 15603783

Start: 2156643

End: 2157974

Strand: Direct

Name: dcuB [H]

Synonym: PM1918

Alternate gene names: 15603783

Gene position: 2156643-2157974 (Clockwise)

Preceding gene: 15603782

Following gene: 15603784

Centisome position: 95.53

GC content: 42.64

Gene sequence:

>1332_bases
ATGCTTTATTTAGAGTTTTTATTCCTGCTGGTCGCCCTTTATTTGGGTAGCCGTTTTGGCGGGATCGGGCTTGGTGTGGT
ATCTGGTATTGGTTTATTAATTGAAGTCTTTATTTTCCGCATGCCTCCAACTTCACCACCGATTGAAGTGATGTTAATTA
TTTTAGCCGTCGTGACTTGTGCTTCCATTTTAGAAGCTGCGGGCGGGCTAAAATTCATGTTGCAGATCGCAGAGCGAGTG
TTACGCAGTAATCCAAAACGTGTCACCATTTTGGGACCTTTAGTGACATATACGATGACCTTTATGCTCGGTACGGGTCA
TGCCGTTTATTCGATTATGCCAATCATTGGTGATGTGGCATTAAAAAATAAAATTCGTCCAGAACGCCCGATGGCTGCGG
CTTCTGTGGCTTCACAACTTGCGATTACGTCGAGCCCAATTTCTGCGGCAGTGGTGTATTATTTAGCACAAATCGTTGCC
CTGCCGGGTTTTGAACATGTCACCTTGTTAAGCATTATTTCTGTGACTGTACCGGCGACTTTAATCGGCACGATTGCATT
GTCTTTATATAGCTTACGTCGCGGTAAAGAACTCGAGGCTGATCCTGAATATCAGCGTCGTTTAGAAGATCCAGTTTGGC
GTGATCGTATTTTAAATACCACGAGTACATCTTTAAACGAAACATTGCCTCCAGCGGCAAGACATGCGGTTTATTTATTC
TTATTAGCCTTAATTACTATTGTAATTATCGCGATGTTCCCTGAGATTCGTACTATTGGTGAAGCGAAAAAACCGATTTC
TATGTCATTAATTATTCAAATGATGATGCTCGGTTTCGGGGGGATTATTTTATTGGTGACCAAAACCAATGTCCAAACTG
TACCAAATGGCGTGGTCTTTAAATCGGGTATGGTTGCAGCCATTGCGATTTTCGGTATCGCTTGGATGAGTGATACTTAT
TTCCAATATGCAATGCCGTCGTTTAAAGCGGGTATTACAGAAATGGTACAAACCTATCCATGGACATTCGCCTTTGCCTT
GTTTGCGGTATCTGTGGTGATTAACAGCCAAGCAGCAACCGCACGGATGTTATTACCAGTAGGGATTGCGATGGGATTAC
CAGCACCATTACTTATCGGATTAATGCCGGCAACCTATGGTTATTTCTTTATCCCGAACTATCCATCTGATATTGCCACC
GTGAACTTTGATGTGACAGGCACAACCAAAATTGGTAAATATTACTTTAACCACAGTTTCATGGTGCCGGGATTAATTGG
TGTGGTGACAGCCTGTTGTGTAGGATATACCTTGGCACAAATTCTGATTTAA

Upstream 100 bases:

>100_bases
TATAAAAAATTACATCAAAGAGAATGAAAACGATTGTGTGCAAAGAGAAATCAAGTATGATTGTTTCTAGAATTTTTTAT
AACATTTTAGAGGTATATTT

Downstream 100 bases:

>100_bases
GTATTCTTTTTCTGTTTTCCCATGCGGTCATAAAGTAATTTATTGACCGCATTTTTTTACTTGAGCATAATCAATACCTT
GATATTCAGTAGGCACTTAG

Product: anaerobic C4-dicarboxylate transporter

Products: C4-dicarboxylates [Periplasm]; C4-dicarboxylates [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 443; Mature: 443

Protein sequence:

>443_residues
MLYLEFLFLLVALYLGSRFGGIGLGVVSGIGLLIEVFIFRMPPTSPPIEVMLIILAVVTCASILEAAGGLKFMLQIAERV
LRSNPKRVTILGPLVTYTMTFMLGTGHAVYSIMPIIGDVALKNKIRPERPMAAASVASQLAITSSPISAAVVYYLAQIVA
LPGFEHVTLLSIISVTVPATLIGTIALSLYSLRRGKELEADPEYQRRLEDPVWRDRILNTTSTSLNETLPPAARHAVYLF
LLALITIVIIAMFPEIRTIGEAKKPISMSLIIQMMMLGFGGIILLVTKTNVQTVPNGVVFKSGMVAAIAIFGIAWMSDTY
FQYAMPSFKAGITEMVQTYPWTFAFALFAVSVVINSQAATARMLLPVGIAMGLPAPLLIGLMPATYGYFFIPNYPSDIAT
VNFDVTGTTKIGKYYFNHSFMVPGLIGVVTACCVGYTLAQILI

Sequences:

>Translated_443_residues
MLYLEFLFLLVALYLGSRFGGIGLGVVSGIGLLIEVFIFRMPPTSPPIEVMLIILAVVTCASILEAAGGLKFMLQIAERV
LRSNPKRVTILGPLVTYTMTFMLGTGHAVYSIMPIIGDVALKNKIRPERPMAAASVASQLAITSSPISAAVVYYLAQIVA
LPGFEHVTLLSIISVTVPATLIGTIALSLYSLRRGKELEADPEYQRRLEDPVWRDRILNTTSTSLNETLPPAARHAVYLF
LLALITIVIIAMFPEIRTIGEAKKPISMSLIIQMMMLGFGGIILLVTKTNVQTVPNGVVFKSGMVAAIAIFGIAWMSDTY
FQYAMPSFKAGITEMVQTYPWTFAFALFAVSVVINSQAATARMLLPVGIAMGLPAPLLIGLMPATYGYFFIPNYPSDIAT
VNFDVTGTTKIGKYYFNHSFMVPGLIGVVTACCVGYTLAQILI
>Mature_443_residues
MLYLEFLFLLVALYLGSRFGGIGLGVVSGIGLLIEVFIFRMPPTSPPIEVMLIILAVVTCASILEAAGGLKFMLQIAERV
LRSNPKRVTILGPLVTYTMTFMLGTGHAVYSIMPIIGDVALKNKIRPERPMAAASVASQLAITSSPISAAVVYYLAQIVA
LPGFEHVTLLSIISVTVPATLIGTIALSLYSLRRGKELEADPEYQRRLEDPVWRDRILNTTSTSLNETLPPAARHAVYLF
LLALITIVIIAMFPEIRTIGEAKKPISMSLIIQMMMLGFGGIILLVTKTNVQTVPNGVVFKSGMVAAIAIFGIAWMSDTY
FQYAMPSFKAGITEMVQTYPWTFAFALFAVSVVINSQAATARMLLPVGIAMGLPAPLLIGLMPATYGYFFIPNYPSDIAT
VNFDVTGTTKIGKYYFNHSFMVPGLIGVVTACCVGYTLAQILI

Specific function: Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane [H]

COG id: COG2704

COG function: function code R; Anaerobic C4-dicarboxylate transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dcuA/dcuB transporter (TC 2.A.13.1) family [H]

Homologues:

Organism=Escherichia coli, GI1790565, Length=405, Percent_Identity=44.6913580246914, Blast_Score=358, Evalue=1e-100,
Organism=Escherichia coli, GI1790580, Length=445, Percent_Identity=35.7303370786517, Blast_Score=265, Evalue=3e-72,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004668 [H]

Pfam domain/function: PF03605 DcuA_DcuB [H]

EC number: NA

Molecular weight: Translated: 48000; Mature: 48000

Theoretical pI: Translated: 9.26; Mature: 9.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLYLEFLFLLVALYLGSRFGGIGLGVVSGIGLLIEVFIFRMPPTSPPIEVMLIILAVVTC
CHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
ASILEAAGGLKFMLQIAERVLRSNPKRVTILGPLVTYTMTFMLGTGHAVYSIMPIIGDVA
HHHHHHHCCHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
LKNKIRPERPMAAASVASQLAITSSPISAAVVYYLAQIVALPGFEHVTLLSIISVTVPAT
HHCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
LIGTIALSLYSLRRGKELEADPEYQRRLEDPVWRDRILNTTSTSLNETLPPAARHAVYLF
HHHHHHHHHHHHHCCCCCCCCCHHHHHHCCHHHHHHHCCCCCCCHHHCCCHHHHHHHHHH
LLALITIVIIAMFPEIRTIGEAKKPISMSLIIQMMMLGFGGIILLVTKTNVQTVPNGVVF
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCEECCCCEEE
KSGMVAAIAIFGIAWMSDTYFQYAMPSFKAGITEMVQTYPWTFAFALFAVSVVINSQAAT
CCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHH
ARMLLPVGIAMGLPAPLLIGLMPATYGYFFIPNYPSDIATVNFDVTGTTKIGKYYFNHSF
HHHHHHHHHHHCCCHHHHHHHHHHHCCEEECCCCCCCCEEEEEEECCCHHHHHHHHCCCC
MVPGLIGVVTACCVGYTLAQILI
HHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MLYLEFLFLLVALYLGSRFGGIGLGVVSGIGLLIEVFIFRMPPTSPPIEVMLIILAVVTC
CHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
ASILEAAGGLKFMLQIAERVLRSNPKRVTILGPLVTYTMTFMLGTGHAVYSIMPIIGDVA
HHHHHHHCCHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
LKNKIRPERPMAAASVASQLAITSSPISAAVVYYLAQIVALPGFEHVTLLSIISVTVPAT
HHCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
LIGTIALSLYSLRRGKELEADPEYQRRLEDPVWRDRILNTTSTSLNETLPPAARHAVYLF
HHHHHHHHHHHHHCCCCCCCCCHHHHHHCCHHHHHHHCCCCCCCHHHCCCHHHHHHHHHH
LLALITIVIIAMFPEIRTIGEAKKPISMSLIIQMMMLGFGGIILLVTKTNVQTVPNGVVF
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCEECCCCEEE
KSGMVAAIAIFGIAWMSDTYFQYAMPSFKAGITEMVQTYPWTFAFALFAVSVVINSQAAT
CCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHH
ARMLLPVGIAMGLPAPLLIGLMPATYGYFFIPNYPSDIATVNFDVTGTTKIGKYYFNHSF
HHHHHHHHHHHCCCHHHHHHHHHHHCCEEECCCCCCCCEEEEEEECCCHHHHHHHHCCCC
MVPGLIGVVTACCVGYTLAQILI
HHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: C4-dicarboxylates [Periplasm]; C4-dicarboxylates [Periplasm] [C]

Specific reaction: C4-dicarboxylates [Periplasm] + C4-dicarboxylates [Periplasm] = C4-dicarboxylates [Periplasm] + C4-dicarboxylates [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]