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The map label for this gene is copA [C]

Identifier: 15603756

GI number: 15603756

Start: 2132147

End: 2132359

Strand: Direct

Name: copA [C]

Synonym: PM1891

Alternate gene names: 15603756

Gene position: 2132147-2132359 (Clockwise)

Preceding gene: 15603755

Following gene: 15603757

Centisome position: 94.45

GC content: 43.19

Gene sequence:

>213_bases
ATGCAAACTGTGACACTGAATATTGAGGGGATGCACTGTGGTGGTTGTGTCAAAACTGTAGAGCGCGTATTGAATGGGTT
AGACGGCGTAACACAAGTGGACGTGAACTTAGAGCACGCTTGTGCCACAATTCAATATGACACCAATCGCGTGTCCATTG
CTCAATTAATTGATGTGGTGGAAAATGCAGGTTTTGATGTACAACCTATTTAA

Upstream 100 bases:

>100_bases
GAAACTTTTTCAATAACATTGCTGTGTAAGCACAGTGTGGTCATTGTTAAAGCCGTTTTGTTATTCAATTTGCTAACATA
AAAACAAGGAGGAAGACCTC

Downstream 100 bases:

>100_bases
CCATTGATGTGATGGCGTTTCAGGGTGAGCTTAGCTCACCTTTGCTATTTGCGTTGCATGAGAGCACGCAAGTGAACGTT
TTACTCGGTCCTTTTTATTA

Product: hypothetical protein

Products: ADP; Orthophosphate. [C]

Alternate protein names: NA

Number of amino acids: Translated: 70; Mature: 70

Protein sequence:

>70_residues
MQTVTLNIEGMHCGGCVKTVERVLNGLDGVTQVDVNLEHACATIQYDTNRVSIAQLIDVVENAGFDVQPI

Sequences:

>Translated_70_residues
MQTVTLNIEGMHCGGCVKTVERVLNGLDGVTQVDVNLEHACATIQYDTNRVSIAQLIDVVENAGFDVQPI
>Mature_70_residues
MQTVTLNIEGMHCGGCVKTVERVLNGLDGVTQVDVNLEHACATIQYDTNRVSIAQLIDVVENAGFDVQPI

Specific function: Involved In Copper Efflux. [C]

COG id: COG2608

COG function: function code P; Copper chaperone

Gene ontology:

Cell location: Integral Membrane Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HMA domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001757
- InterPro:   IPR017969
- InterPro:   IPR006121 [H]

Pfam domain/function: PF00403 HMA [H]

EC number: 3.6.3.4 [C]

Molecular weight: Translated: 7558; Mature: 7558

Theoretical pI: Translated: 4.13; Mature: 4.13

Prosite motif: PS01047 HMA_1 ; PS50846 HMA_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
7.1 %Cys+Met (Translated Protein)
4.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
7.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTVTLNIEGMHCGGCVKTVERVLNGLDGVTQVDVNLEHACATIQYDTNRVSIAQLIDVV
CCEEEEEECCEECCHHHHHHHHHHHCCCCCEEECCCCCCEEEEEEECCCEEHHHHHHHHH
ENAGFDVQPI
HCCCCCCCCC
>Mature Secondary Structure
MQTVTLNIEGMHCGGCVKTVERVLNGLDGVTQVDVNLEHACATIQYDTNRVSIAQLIDVV
CCEEEEEECCEECCHHHHHHHHHHHCCCCCEEECCCCCCEEEEEEECCCEEHHHHHHHHH
ENAGFDVQPI
HCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Cu [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O [C]

Specific reaction: ATP + H2O = ADP + Orthophosphate. [C]

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800; 10675023 [H]