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The map label for this gene is yfiC [C]

Identifier: 15603704

GI number: 15603704

Start: 2078324

End: 2079037

Strand: Reverse

Name: yfiC [C]

Synonym: PM1839

Alternate gene names: 15603704

Gene position: 2079037-2078324 (Counterclockwise)

Preceding gene: 15603708

Following gene: 15603702

Centisome position: 92.1

GC content: 43.42

Gene sequence:

>714_bases
ATGTCAGCAAAACAAAACGGTTTTACCTTTAAACAATTTCATATTGATCACCATCGTTGTGCAATGAAAGTAGGCACTGA
CGGGATTTTATTAGGCGCGTGGGCGGATGTCAGTCAATCTGAACGGATTCTCGATTTGGGAACTGGCACAGGTTTAATCG
CCTTGATGTTAGCGCAACGTAGCACCAAAGAAAGCGAAATTCATGCCGTCGAATTAGATCAGGCTGCTTATTTGCAAGCA
CAGGCAAATGTTCACGCTTCGCCATGGGCACAGCGTGTGCATGTCTATCAACAAGATGCCGCCGAATTTTGCCGAAACGC
TGTGAATAAGTTTGATTTAATTGTGGCAAATCCCCCTTATTTTCCACAGGGTGTGGATTGTGCCACGCCACAACGTGATC
TGGCACGTTATACTGCCACGCATCGTCATGTTGATTGGTTAAATTGGGCATCTCATTGTCTTAGCGAGCAAGGCAAAATC
AGCATGGTGTTGCCTTTTGAGGCGGGTGAAACGTTGTTAAAACAGACCGCACTTTATTGTATTGCCCGTTGTGAAGTGAT
CACTAAAAAAGGCAAAGCTCCACAACGTTTACTTCTCACATTTTCTTTGCAAGCCCAACCGTTGCAGCCAAGCCAATTGA
TTATTTATGATGAAAGCAATCGCTATCATCCGGATTTTATTGGCTTAACCAAAGATTTTTATTTAGCGTTTTAA

Upstream 100 bases:

>100_bases
TCTATCATTGTAAAATTGTGGCAGATTATAGCGCACTTTGTCCGTGTTGCGAAATGAAGACGCTATTTATACCAAAAGGC
GGTCAATATTAAGGAAATGT

Downstream 100 bases:

>100_bases
ACACACAAAAAGGGAGCGAATATCGCTCCCATATCAATTGATAAAGTTTATTGTACTGACTGACGATGGGCTTTTTCCAA
TTTTGTCCAGTTGTAATAGC

Product: hypothetical protein

Products: NA

Alternate protein names: tRNA m6A37 methyltransferase

Number of amino acids: Translated: 237; Mature: 236

Protein sequence:

>237_residues
MSAKQNGFTFKQFHIDHHRCAMKVGTDGILLGAWADVSQSERILDLGTGTGLIALMLAQRSTKESEIHAVELDQAAYLQA
QANVHASPWAQRVHVYQQDAAEFCRNAVNKFDLIVANPPYFPQGVDCATPQRDLARYTATHRHVDWLNWASHCLSEQGKI
SMVLPFEAGETLLKQTALYCIARCEVITKKGKAPQRLLLTFSLQAQPLQPSQLIIYDESNRYHPDFIGLTKDFYLAF

Sequences:

>Translated_237_residues
MSAKQNGFTFKQFHIDHHRCAMKVGTDGILLGAWADVSQSERILDLGTGTGLIALMLAQRSTKESEIHAVELDQAAYLQA
QANVHASPWAQRVHVYQQDAAEFCRNAVNKFDLIVANPPYFPQGVDCATPQRDLARYTATHRHVDWLNWASHCLSEQGKI
SMVLPFEAGETLLKQTALYCIARCEVITKKGKAPQRLLLTFSLQAQPLQPSQLIIYDESNRYHPDFIGLTKDFYLAF
>Mature_236_residues
SAKQNGFTFKQFHIDHHRCAMKVGTDGILLGAWADVSQSERILDLGTGTGLIALMLAQRSTKESEIHAVELDQAAYLQAQ
ANVHASPWAQRVHVYQQDAAEFCRNAVNKFDLIVANPPYFPQGVDCATPQRDLARYTATHRHVDWLNWASHCLSEQGKIS
MVLPFEAGETLLKQTALYCIARCEVITKKGKAPQRLLLTFSLQAQPLQPSQLIIYDESNRYHPDFIGLTKDFYLAF

Specific function: Specifically methylates the adenine in position 37 of tRNA(Val)

COG id: COG4123

COG function: function code R; Predicted O-methyltransferase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. tRNA (adenine-N(6)-)-methyltransferase family

Homologues:

Organism=Escherichia coli, GI87082131, Length=235, Percent_Identity=45.9574468085106, Blast_Score=215, Evalue=2e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): TRMN6_PASMU (Q9CJZ9)

Other databases:

- EMBL:   AE004439
- RefSeq:   NP_246778.1
- ProteinModelPortal:   Q9CJZ9
- GeneID:   1245186
- GenomeReviews:   AE004439_GR
- KEGG:   pmu:PM1839
- NMPDR:   fig|272843.1.peg.1840
- HOGENOM:   HBG307609
- OMA:   FKQFHIN
- ProtClustDB:   CLSK870634
- BioCyc:   PMUL272843:PM1839-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01872
- InterPro:   IPR002052
- InterPro:   IPR002296
- InterPro:   IPR007848
- InterPro:   IPR022882
- PRINTS:   PR00507

Pfam domain/function: PF05175 MTS

EC number: =2.1.1.55

Molecular weight: Translated: 26662; Mature: 26530

Theoretical pI: Translated: 7.29; Mature: 7.29

Prosite motif: PS00092 N6_MTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAKQNGFTFKQFHIDHHRCAMKVGTDGILLGAWADVSQSERILDLGTGTGLIALMLAQR
CCCCCCCCEEEEEECCHHHEEEEECCCCEEEEEECCCCCCCEEEEECCCHHHHHHHHHHC
STKESEIHAVELDQAAYLQAQANVHASPWAQRVHVYQQDAAEFCRNAVNKFDLIVANPPY
CCCCCCEEEEEECHHHEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCC
FPQGVDCATPQRDLARYTATHRHVDWLNWASHCLSEQGKISMVLPFEAGETLLKQTALYC
CCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHH
IARCEVITKKGKAPQRLLLTFSLQAQPLQPSQLIIYDESNRYHPDFIGLTKDFYLAF
HHHHHHHHCCCCCCCEEEEEEEECCCCCCCCEEEEEECCCCCCCCEECCCCEEEEEC
>Mature Secondary Structure 
SAKQNGFTFKQFHIDHHRCAMKVGTDGILLGAWADVSQSERILDLGTGTGLIALMLAQR
CCCCCCCEEEEEECCHHHEEEEECCCCEEEEEECCCCCCCEEEEECCCHHHHHHHHHHC
STKESEIHAVELDQAAYLQAQANVHASPWAQRVHVYQQDAAEFCRNAVNKFDLIVANPPY
CCCCCCEEEEEECHHHEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCC
FPQGVDCATPQRDLARYTATHRHVDWLNWASHCLSEQGKISMVLPFEAGETLLKQTALYC
CCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHH
IARCEVITKKGKAPQRLLLTFSLQAQPLQPSQLIIYDESNRYHPDFIGLTKDFYLAF
HHHHHHHHCCCCCCCEEEEEEEECCCCCCCCEEEEEECCCCCCCCEECCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11248100