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The map label for this gene is nusG

Identifier: 15603609

GI number: 15603609

Start: 1966243

End: 1966794

Strand: Reverse

Name: nusG

Synonym: PM1744

Alternate gene names: 15603609

Gene position: 1966794-1966243 (Counterclockwise)

Preceding gene: 15603610

Following gene: 15603608

Centisome position: 87.12

GC content: 40.04

Gene sequence:

>552_bases
ATGACAGAAACAACAACCAAAAAACGTTGGTATGTGTTACAGGCTTTTTCTGGTTTTGAAGGTCGTGTTGCAACAACATT
GCGTGAATATATTAAGTTACACCAAATGGAAGATCAATTTGGTGAAGTGCTTGTGCCGACAGAAGAAGTCGTAGAAAACG
TAGCCGGAAAAAGACGTAAAAGTGAGCGCAAATTTTTTCCAGGTTATGTGTTAGTGCAAATGGAAATGAATGACGAAACT
TGGCATTTAGTACGCAGTGTACCACGTGTTATGGGTTTTATTGGTGGTACAGCAGATAAACCAGCGCCAATTTCACAGCG
TGAAGCGGATCGTATTTTAAATCGTTTACAAGAAAGTTCAGAAAAACCTCGCCACAGAAAAGAATTCCAGCCTGGTGAAG
AAGTTCGCGTCACTGAAGGACCATTCGCTGACTTTAATGGTACAGTGGAAGAAGTGGATTATGAAAAAGGTCGCTTAAAA
GTGTCTGTTTCTATCTTTGGTCGTGCAACACCTGTTGAACTTGAATTCAGCCAAGTTGAGAAAACAAATTAA

Upstream 100 bases:

>100_bases
ATTGTGGCAGGTGTAACGATTGTTGTGTCTTTAATCCTGTGGGGATTAGATTCAGTGATTGTTGCGTTAATTACTTTCTT
AACAGATTTGAGGTTCTAAA

Downstream 100 bases:

>100_bases
TTTTTAACCGCACTTAGCTATTCTACTTAATCGATAAGTGTGGTCAGTTTATTGAGTAATTTTTACTTGAAGTTTGGGTT
GTGTTTAATTACAATACAGC

Product: transcription antitermination protein NusG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 183; Mature: 182

Protein sequence:

>183_residues
MTETTTKKRWYVLQAFSGFEGRVATTLREYIKLHQMEDQFGEVLVPTEEVVENVAGKRRKSERKFFPGYVLVQMEMNDET
WHLVRSVPRVMGFIGGTADKPAPISQREADRILNRLQESSEKPRHRKEFQPGEEVRVTEGPFADFNGTVEEVDYEKGRLK
VSVSIFGRATPVELEFSQVEKTN

Sequences:

>Translated_183_residues
MTETTTKKRWYVLQAFSGFEGRVATTLREYIKLHQMEDQFGEVLVPTEEVVENVAGKRRKSERKFFPGYVLVQMEMNDET
WHLVRSVPRVMGFIGGTADKPAPISQREADRILNRLQESSEKPRHRKEFQPGEEVRVTEGPFADFNGTVEEVDYEKGRLK
VSVSIFGRATPVELEFSQVEKTN
>Mature_182_residues
TETTTKKRWYVLQAFSGFEGRVATTLREYIKLHQMEDQFGEVLVPTEEVVENVAGKRRKSERKFFPGYVLVQMEMNDETW
HLVRSVPRVMGFIGGTADKPAPISQREADRILNRLQESSEKPRHRKEFQPGEEVRVTEGPFADFNGTVEEVDYEKGRLKV
SVSIFGRATPVELEFSQVEKTN

Specific function: Influences transcription termination and antitermination. Acts as a component of the transcription complex, and interacts with the termination factor rho and RNA polymerase

COG id: COG0250

COG function: function code K; Transcription antiterminator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KOW domain

Homologues:

Organism=Escherichia coli, GI1790414, Length=176, Percent_Identity=79.5454545454545, Blast_Score=293, Evalue=5e-81,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NUSG_PASMU (Q9CK84)

Other databases:

- EMBL:   AE004439
- RefSeq:   NP_246683.1
- ProteinModelPortal:   Q9CK84
- SMR:   Q9CK84
- GeneID:   1245091
- GenomeReviews:   AE004439_GR
- KEGG:   pmu:PM1744
- NMPDR:   fig|272843.1.peg.1745
- HOGENOM:   HBG751162
- OMA:   VASGCEK
- ProtClustDB:   PRK05609
- BioCyc:   PMUL272843:PM1744-MONOMER
- InterPro:   IPR005824
- InterPro:   IPR001062
- InterPro:   IPR015869
- InterPro:   IPR006645
- InterPro:   IPR014722
- InterPro:   IPR008991
- Gene3D:   G3DSA:2.30.30.30
- Gene3D:   G3DSA:3.30.70.940
- PRINTS:   PR00338
- SMART:   SM00739
- SMART:   SM00738
- TIGRFAMs:   TIGR00922

Pfam domain/function: PF00467 KOW; PF02357 NusG; SSF82679 Transcrpt_antiterm_NusG_N; SSF50104 Transl_SH3_like

EC number: NA

Molecular weight: Translated: 21114; Mature: 20983

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: PS01014 NUSG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTETTTKKRWYVLQAFSGFEGRVATTLREYIKLHQMEDQFGEVLVPTEEVVENVAGKRRK
CCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCEECCHHHHHHHHHHHHHH
SERKFFPGYVLVQMEMNDETWHLVRSVPRVMGFIGGTADKPAPISQREADRILNRLQESS
HCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHH
EKPRHRKEFQPGEEVRVTEGPFADFNGTVEEVDYEKGRLKVSVSIFGRATPVELEFSQVE
CCCCHHHHCCCCCCEEECCCCCCCCCCCHHHCCCCCCEEEEEEEEECCCCCCEEEHHHHC
KTN
CCC
>Mature Secondary Structure 
TETTTKKRWYVLQAFSGFEGRVATTLREYIKLHQMEDQFGEVLVPTEEVVENVAGKRRK
CCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCEECCHHHHHHHHHHHHHH
SERKFFPGYVLVQMEMNDETWHLVRSVPRVMGFIGGTADKPAPISQREADRILNRLQESS
HCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHH
EKPRHRKEFQPGEEVRVTEGPFADFNGTVEEVDYEKGRLKVSVSIFGRATPVELEFSQVE
CCCCHHHHCCCCCCEEECCCCCCCCCCCHHHCCCCCCEEEEEEEEECCCCCCEEEHHHHC
KTN
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11248100