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The map label for this gene is hupA

Identifier: 15603597

GI number: 15603597

Start: 1949201

End: 1949473

Strand: Reverse

Name: hupA

Synonym: PM1732

Alternate gene names: 15603597

Gene position: 1949473-1949201 (Counterclockwise)

Preceding gene: 15603598

Following gene: 15603596

Centisome position: 86.36

GC content: 41.76

Gene sequence:

>273_bases
ATGAACAAAACGGATTTAATTGATGCGATTGCAAGTGCGGCTGAGTTAAACAAGAAGCAAGCAAAAGCAGCATTAGAAGC
AACTCTAGAAGCGATTTCTGGTAGTTTAAAAGCGGGTGAACCAGTGCAATTAATCGGCTTTGGTACATTCAAAGTAAATT
CACGCAAAGCGCGTACAGGGCGTAACCCACAAACAGGTGCAGAAATCAAAATTGCTGCTTCTAAAGTGCCTGCTTTCGTT
GCCGGTAAAGCCTTAAAAGACGCTGTTAAATAA

Upstream 100 bases:

>100_bases
TAGATTAAGCTTGGCATTGCTGTGTCTACAGTAATCATTTTATCGGAAACACATCATGTCTTTCCTCACGATTTAAATAA
AAAGTAGAAGGTATTTATTT

Downstream 100 bases:

>100_bases
TTAAGTCATACTTTTTCATATTTCTAAAAAGCTCTGTGAACGCATCACAGAGCTTTTTCATATGTACACAAACACTCCAA
ATGAATCGGTTTTCTGTATT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 90; Mature: 90

Protein sequence:

>90_residues
MNKTDLIDAIASAAELNKKQAKAALEATLEAISGSLKAGEPVQLIGFGTFKVNSRKARTGRNPQTGAEIKIAASKVPAFV
AGKALKDAVK

Sequences:

>Translated_90_residues
MNKTDLIDAIASAAELNKKQAKAALEATLEAISGSLKAGEPVQLIGFGTFKVNSRKARTGRNPQTGAEIKIAASKVPAFV
AGKALKDAVK
>Mature_90_residues
MNKTDLIDAIASAAELNKKQAKAALEATLEAISGSLKAGEPVQLIGFGTFKVNSRKARTGRNPQTGAEIKIAASKVPAFV
AGKALKDAVK

Specific function: Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions

COG id: COG0776

COG function: function code L; Bacterial nucleoid DNA-binding protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial histone-like protein family

Homologues:

Organism=Escherichia coli, GI1790433, Length=90, Percent_Identity=76.6666666666667, Blast_Score=136, Evalue=3e-34,
Organism=Escherichia coli, GI1786644, Length=89, Percent_Identity=61.7977528089888, Blast_Score=108, Evalue=9e-26,
Organism=Escherichia coli, GI1787141, Length=88, Percent_Identity=36.3636363636364, Blast_Score=70, Evalue=3e-14,
Organism=Escherichia coli, GI1788005, Length=90, Percent_Identity=36.6666666666667, Blast_Score=65, Evalue=1e-12,

Paralogues:

None

Copy number: 1380 Molecules/Cell In: Growth-Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): DBH_PASMU (Q9CK94)

Other databases:

- EMBL:   AE004439
- RefSeq:   NP_246671.1
- ProteinModelPortal:   Q9CK94
- SMR:   Q9CK94
- GeneID:   1245079
- GenomeReviews:   AE004439_GR
- KEGG:   pmu:PM1732
- NMPDR:   fig|272843.1.peg.1733
- HOGENOM:   HBG705085
- OMA:   ISAMAEK
- ProtClustDB:   CLSK870593
- BioCyc:   PMUL272843:PM1732-MONOMER
- InterPro:   IPR000119
- InterPro:   IPR020816
- InterPro:   IPR010992
- Gene3D:   G3DSA:4.10.520.10
- PRINTS:   PR01727
- SMART:   SM00411

Pfam domain/function: PF00216 Bac_DNA_binding; SSF47729 IHF_like_DNA_bnd

EC number: NA

Molecular weight: Translated: 9307; Mature: 9307

Theoretical pI: Translated: 10.79; Mature: 10.79

Prosite motif: PS00045 HISTONE_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKTDLIDAIASAAELNKKQAKAALEATLEAISGSLKAGEPVQLIGFGTFKVNSRKARTG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEEEECCCCCCCC
RNPQTGAEIKIAASKVPAFVAGKALKDAVK
CCCCCCCEEEEECCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MNKTDLIDAIASAAELNKKQAKAALEATLEAISGSLKAGEPVQLIGFGTFKVNSRKARTG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEEEECCCCCCCC
RNPQTGAEIKIAASKVPAFVAGKALKDAVK
CCCCCCCEEEEECCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11248100