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The map label for this gene is rpiR [C]

Identifier: 15603579

GI number: 15603579

Start: 1922061

End: 1922927

Strand: Direct

Name: rpiR [C]

Synonym: PM1714

Alternate gene names: 15603579

Gene position: 1922061-1922927 (Clockwise)

Preceding gene: 15603578

Following gene: 15603580

Centisome position: 85.14

GC content: 38.87

Gene sequence:

>867_bases
ATGTTAATTAGTGGAAAAATTTTAGACACGATTGGTGCACTACATGATAGTTTAACCAAAACAGAAAAAAGAATTGCAGC
GACAATTCTCGCCTCACCTGATTTATTAAGTCAGTCTTCACTGTCTGATATTGCTAAACATCTTGATGTGGGCGAAGCCA
CTTTCATTCGTTTCTGTCGTACATTAGGCTTTAGAGGCTTCACTGACTTTAAATTAGAACTTGCTATTGAATTAGCCACA
AGAGAAAAGCAATATCATTCTTTACTTGATACGGACATTTCACCTTCTGATGATCCTAAAAATATCGCGGCGAAATTACA
GGGTGCAGTGACGAATGTCATTGCTGAAACCATTAACTTACTCGATTTTAATGAGTTAGAAAAAGTGGTGAATACCATGA
TGAAAGCCAAACGCATTTTTCTCTTCGGCGTGGGCTCATCTGGAATAACCGCAGAAGATGCAAAAAATAAATTCATGCGC
ATCGGTTTACAAGTGGATTCCACCTCAAATAACCACTTTATGTATATGCAAGCTGCACTCATGCAAGAAGGTGATGTTGT
AGTCGGTATTAGTCATTCTGGTTATTCGAAAGAAGTCATTCAAGCACTAAACATCGCGAAAAAGAATAGCGCAACCACTA
TCGCGATTACGCATAATTTGCGTTCACCCATTACGCACGCTGCGGATTATGTCCTGATTAATGGTAATCGCCAAGGGCAA
CTACAAGGTGATTCAATGGGAACAAAAATTGCTCAGCTTTTCGTTTTAGATTTGATCTACACCTTAATCGTACAAGCGAC
GGAAGATACAGCCACTAAAACGAAGCAAAAAACCGTTAACGTCATTCTCGAACAACGTGTTAAATAA

Upstream 100 bases:

>100_bases
CTGGCTGTAATGTGGATAACCAAGTGATAAGTTTGAAAAAACTTGTCGTAAAAGTGCCGGTTGAATTGCTGTGATTCACC
CCACATTGTAAGGAGCCTCT

Downstream 100 bases:

>100_bases
CACATCTATAGGAGTATCCAATGAAAAACTTAAAAGGTATCTTCAGTGCATTGTTAGTTTCTTTCAACGCTGATGGTTCA
ATCAATGAAAAAGGCTTACG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 288; Mature: 288

Protein sequence:

>288_residues
MLISGKILDTIGALHDSLTKTEKRIAATILASPDLLSQSSLSDIAKHLDVGEATFIRFCRTLGFRGFTDFKLELAIELAT
REKQYHSLLDTDISPSDDPKNIAAKLQGAVTNVIAETINLLDFNELEKVVNTMMKAKRIFLFGVGSSGITAEDAKNKFMR
IGLQVDSTSNNHFMYMQAALMQEGDVVVGISHSGYSKEVIQALNIAKKNSATTIAITHNLRSPITHAADYVLINGNRQGQ
LQGDSMGTKIAQLFVLDLIYTLIVQATEDTATKTKQKTVNVILEQRVK

Sequences:

>Translated_288_residues
MLISGKILDTIGALHDSLTKTEKRIAATILASPDLLSQSSLSDIAKHLDVGEATFIRFCRTLGFRGFTDFKLELAIELAT
REKQYHSLLDTDISPSDDPKNIAAKLQGAVTNVIAETINLLDFNELEKVVNTMMKAKRIFLFGVGSSGITAEDAKNKFMR
IGLQVDSTSNNHFMYMQAALMQEGDVVVGISHSGYSKEVIQALNIAKKNSATTIAITHNLRSPITHAADYVLINGNRQGQ
LQGDSMGTKIAQLFVLDLIYTLIVQATEDTATKTKQKTVNVILEQRVK
>Mature_288_residues
MLISGKILDTIGALHDSLTKTEKRIAATILASPDLLSQSSLSDIAKHLDVGEATFIRFCRTLGFRGFTDFKLELAIELAT
REKQYHSLLDTDISPSDDPKNIAAKLQGAVTNVIAETINLLDFNELEKVVNTMMKAKRIFLFGVGSSGITAEDAKNKFMR
IGLQVDSTSNNHFMYMQAALMQEGDVVVGISHSGYSKEVIQALNIAKKNSATTIAITHNLRSPITHAADYVLINGNRQGQ
LQGDSMGTKIAQLFVLDLIYTLIVQATEDTATKTKQKTVNVILEQRVK

Specific function: Regulatory Protein Involved In Rpib Gene Repression. Also Involved In Als Operon Repression. [C]

COG id: COG1737

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI87082369, Length=268, Percent_Identity=29.4776119402985, Blast_Score=146, Evalue=1e-36,
Organism=Escherichia coli, GI1788767, Length=274, Percent_Identity=31.021897810219, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI1788159, Length=255, Percent_Identity=31.3725490196078, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI87082130, Length=251, Percent_Identity=23.5059760956175, Blast_Score=88, Evalue=8e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000281
- InterPro:   IPR001347
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01418 HTH_6; PF01380 SIS [H]

EC number: NA

Molecular weight: Translated: 31572; Mature: 31572

Theoretical pI: Translated: 7.79; Mature: 7.79

Prosite motif: PS51071 HTH_RPIR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLISGKILDTIGALHDSLTKTEKRIAATILASPDLLSQSSLSDIAKHLDVGEATFIRFCR
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCHHHHHHHHH
TLGFRGFTDFKLELAIELATREKQYHSLLDTDISPSDDPKNIAAKLQGAVTNVIAETINL
HHCCCCCCCEEEEEEEEEHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
LDFNELEKVVNTMMKAKRIFLFGVGSSGITAEDAKNKFMRIGLQVDSTSNNHFMYMQAAL
CCHHHHHHHHHHHHHHCEEEEEEECCCCCCHHHHHCCEEEEEEEEECCCCCEEEEEEEHH
MQEGDVVVGISHSGYSKEVIQALNIAKKNSATTIAITHNLRSPITHAADYVLINGNRQGQ
HCCCCEEEEECCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHCCCEEEEECCCCCC
LQGDSMGTKIAQLFVLDLIYTLIVQATEDTATKTKQKTVNVILEQRVK
CCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLISGKILDTIGALHDSLTKTEKRIAATILASPDLLSQSSLSDIAKHLDVGEATFIRFCR
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCHHHHHHHHH
TLGFRGFTDFKLELAIELATREKQYHSLLDTDISPSDDPKNIAAKLQGAVTNVIAETINL
HHCCCCCCCEEEEEEEEEHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
LDFNELEKVVNTMMKAKRIFLFGVGSSGITAEDAKNKFMRIGLQVDSTSNNHFMYMQAAL
CCHHHHHHHHHHHHHHCEEEEEEECCCCCCHHHHHCCEEEEEEEEECCCCCEEEEEEEHH
MQEGDVVVGISHSGYSKEVIQALNIAKKNSATTIAITHNLRSPITHAADYVLINGNRQGQ
HCCCCEEEEECCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHCCCEEEEECCCCCC
LQGDSMGTKIAQLFVLDLIYTLIVQATEDTATKTKQKTVNVILEQRVK
CCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]