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The map label for this gene is serB [H]

Identifier: 15603522

GI number: 15603522

Start: 1864305

End: 1865267

Strand: Reverse

Name: serB [H]

Synonym: PM1657

Alternate gene names: 15603522

Gene position: 1865267-1864305 (Counterclockwise)

Preceding gene: 161723307

Following gene: 15603521

Centisome position: 82.63

GC content: 40.91

Gene sequence:

>963_bases
ATGCAAACACAAAATCTTGCGACGATTACGCAATTTTTTTCTTCTTTCCCTTGTTCGATTACGAGTAGTGAACCAGTAAC
GGAAGGGAAAACACACATTGTTGTCTATGGAGAAACCTTAAATCTGCTCAAGCTTCGTCAATTTCAACAAAAGTGCGGTG
AAAATTTCATTATTTTAGAAGCTTGGAATGTATTACACAATACGGTCGTATTATTACGAGGGGATTGGCACACACAGTGG
CTCGATTATGCACATGAATTGGGCCTTGATTGTGCATTATTGGATTTTAGTCCTCGTTTAGCACAAGCCGGGTTGTTAGT
GATGGATATGGATTCCACGGCAATTCAAATTGAATGTATTGATGAGATTGCAAAATTAGCTGGAACCGGGGAGTTGGTTT
CTTCCATTACGGCACAAGCCATGCGTGGCGAGTTAGACTTTGAACAAAGTTTACGTCGTCGTGTGAGTACTTTAAAAGGG
GCGCCTGAAACGATTTTGAAGACAGTACGTGATAACTTACCTTTAATGCCCGGTTTAGAAGACACATTAGCAGTATTACA
ACAATATGGTTGGAAAACGGCGATTGCTTCAGGTGGTTTTACGTATTTTACTGATTATCTCAAACAGCGTTTGAAGTTAG
ATTATACCGTTGCAAATCAGTTTGCTATTGAAGAAGGGATACTGACTGGTGAAGTCGCGGGTGACGTGGTTGATGCACAG
TATAAAGCACGTACTTTAGGCGAGTTAGCAGAAAAATTTAACATTGCTTTACAGCAAACGGTGGCGATTGGCGATGGCGC
AAATGATCTGGCTATGCTAAGTGTAGCAGGTATGGGCGTTGCATTACATGCCAAGCCGAAGGTACAACAACAAGCCAAAG
TTGTGGTAAACTTTGCAGACTTTAGCGCACTGTTATGTTTACTGAGTGCAAATGATAAATTGGTTAAAGCAAATAAGGAG
TAA

Upstream 100 bases:

>100_bases
TTTTTCTTTGGTTAAATGCAAGTTATTTTTTCCTAAAGATAAGTAAATGGGCTAGAATACCAACACGTTATTTTCAGCTC
GACAATTTACAGGATTTTCT

Downstream 100 bases:

>100_bases
TGATTTATGCCTTCTTTTGATATCGTATCTGAAATTACCTTACATGAAGTGCGCAATGCCGTCGAAAATGCCAATCGTGA
TTTGACGAATCGCTGGGATT

Product: phosphoserine phosphatase

Products: NA

Alternate protein names: PSP; PSPase; O-phosphoserine phosphohydrolase [H]

Number of amino acids: Translated: 320; Mature: 320

Protein sequence:

>320_residues
MQTQNLATITQFFSSFPCSITSSEPVTEGKTHIVVYGETLNLLKLRQFQQKCGENFIILEAWNVLHNTVVLLRGDWHTQW
LDYAHELGLDCALLDFSPRLAQAGLLVMDMDSTAIQIECIDEIAKLAGTGELVSSITAQAMRGELDFEQSLRRRVSTLKG
APETILKTVRDNLPLMPGLEDTLAVLQQYGWKTAIASGGFTYFTDYLKQRLKLDYTVANQFAIEEGILTGEVAGDVVDAQ
YKARTLGELAEKFNIALQQTVAIGDGANDLAMLSVAGMGVALHAKPKVQQQAKVVVNFADFSALLCLLSANDKLVKANKE

Sequences:

>Translated_320_residues
MQTQNLATITQFFSSFPCSITSSEPVTEGKTHIVVYGETLNLLKLRQFQQKCGENFIILEAWNVLHNTVVLLRGDWHTQW
LDYAHELGLDCALLDFSPRLAQAGLLVMDMDSTAIQIECIDEIAKLAGTGELVSSITAQAMRGELDFEQSLRRRVSTLKG
APETILKTVRDNLPLMPGLEDTLAVLQQYGWKTAIASGGFTYFTDYLKQRLKLDYTVANQFAIEEGILTGEVAGDVVDAQ
YKARTLGELAEKFNIALQQTVAIGDGANDLAMLSVAGMGVALHAKPKVQQQAKVVVNFADFSALLCLLSANDKLVKANKE
>Mature_320_residues
MQTQNLATITQFFSSFPCSITSSEPVTEGKTHIVVYGETLNLLKLRQFQQKCGENFIILEAWNVLHNTVVLLRGDWHTQW
LDYAHELGLDCALLDFSPRLAQAGLLVMDMDSTAIQIECIDEIAKLAGTGELVSSITAQAMRGELDFEQSLRRRVSTLKG
APETILKTVRDNLPLMPGLEDTLAVLQQYGWKTAIASGGFTYFTDYLKQRLKLDYTVANQFAIEEGILTGEVAGDVVDAQ
YKARTLGELAEKFNIALQQTVAIGDGANDLAMLSVAGMGVALHAKPKVQQQAKVVVNFADFSALLCLLSANDKLVKANKE

Specific function: Unknown

COG id: COG0560

COG function: function code E; Phosphoserine phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the serB family [H]

Homologues:

Organism=Homo sapiens, GI46249388, Length=176, Percent_Identity=29.5454545454545, Blast_Score=80, Evalue=4e-15,
Organism=Escherichia coli, GI1790849, Length=311, Percent_Identity=51.1254019292604, Blast_Score=310, Evalue=6e-86,
Organism=Saccharomyces cerevisiae, GI6321647, Length=210, Percent_Identity=39.0476190476191, Blast_Score=147, Evalue=2e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006383
- InterPro:   IPR023190
- InterPro:   IPR004469 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.1.3.3 [H]

Molecular weight: Translated: 35133; Mature: 35133

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTQNLATITQFFSSFPCSITSSEPVTEGKTHIVVYGETLNLLKLRQFQQKCGENFIILE
CCCCHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHCCCEEEEE
AWNVLHNTVVLLRGDWHTQWLDYAHELGLDCALLDFSPRLAQAGLLVMDMDSTAIQIECI
EHHHHHCEEEEEECCCHHHHHHHHHHCCCCEEEECCCHHHHHCCEEEEECCCCEEEEHHH
DEIAKLAGTGELVSSITAQAMRGELDFEQSLRRRVSTLKGAPETILKTVRDNLPLMPGLE
HHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCH
DTLAVLQQYGWKTAIASGGFTYFTDYLKQRLKLDYTVANQFAIEEGILTGEVAGDVVDAQ
HHHHHHHHCCCCEECCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCEECHHHCCHHHHH
YKARTLGELAEKFNIALQQTVAIGDGANDLAMLSVAGMGVALHAKPKVQQQAKVVVNFAD
HHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHEEECCCCEEEECCCCHHHHHHHEEEHHH
FSALLCLLSANDKLVKANKE
HHHHHHHHCCCCCEEECCCC
>Mature Secondary Structure
MQTQNLATITQFFSSFPCSITSSEPVTEGKTHIVVYGETLNLLKLRQFQQKCGENFIILE
CCCCHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHCCCEEEEE
AWNVLHNTVVLLRGDWHTQWLDYAHELGLDCALLDFSPRLAQAGLLVMDMDSTAIQIECI
EHHHHHCEEEEEECCCHHHHHHHHHHCCCCEEEECCCHHHHHCCEEEEECCCCEEEEHHH
DEIAKLAGTGELVSSITAQAMRGELDFEQSLRRRVSTLKGAPETILKTVRDNLPLMPGLE
HHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCH
DTLAVLQQYGWKTAIASGGFTYFTDYLKQRLKLDYTVANQFAIEEGILTGEVAGDVVDAQ
HHHHHHHHCCCCEECCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCEECHHHCCHHHHH
YKARTLGELAEKFNIALQQTVAIGDGANDLAMLSVAGMGVALHAKPKVQQQAKVVVNFAD
HHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHEEECCCCEEEECCCCHHHHHHHEEEHHH
FSALLCLLSANDKLVKANKE
HHHHHHHHCCCCCEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]