Click here to switch to the map view.

The map label for this gene is siaT [H]

Identifier: 15603518

GI number: 15603518

Start: 1861327

End: 1862607

Strand: Direct

Name: siaT [H]

Synonym: PM1653

Alternate gene names: 15603518

Gene position: 1861327-1862607 (Clockwise)

Preceding gene: 15603517

Following gene: 15603523

Centisome position: 82.45

GC content: 38.41

Gene sequence:

>1281_bases
ATGATTGCATTCTTAGTTTTAATTGCACTTGTTCTACTTGTTATGATTAATGTGCCTATCGCAGTAGCAATTGGTATTGT
TTCACTCATAGGTATGTTAATTACAAATAGTTTTGATGCAATATATAACGTCGCACTGTCTGTTTTTGATGGCGCCTCTA
ATTTTTCATTACTTGCTATTCCGCTTTTCATTTTAGCAGGAGCATTAATGAATACAGGGGGAATATCGGTTAGGCTGATT
AATTTTGTTAATGCTTTAATCGGCTTCGTCCGAGGTGGGCTTGCAATGGTCAATGTGGGTGTTTCCATGATCTTTGCTGA
AATTTCCGGATCTTCTGTAGCGGATGTTGCCGCACTGGGTTCTATCCTCATTCCTGCAATGAAAAAAAGAGGTTATAAAT
CAAGCTTTTCTGCTGCTGTTACTTCATCATCGGCTTCCTTAGCGGTGATTATCCCACCCTCACTTCCCATGATTATTTAT
GGTGCGATGGCGGATGTTTCTATTTCTAAGCTTTTTGTGGCAGGACTTGCCGCAGGTGGTGTAGCTTCGTTAGGTATGTT
TGCTGTATGTTATTATTATGCGGTTAAATATAATTTACCGAGGGAAGAACACTTCAGCATGTCCAAATTATGCACAGCAT
TCAAAAATGCGTTCTGGGCGTTAACGTTACCTGTTCTAATTTTAGGTGGGATTATTTCAGGTTTTACCACTGCAACAGAA
GCGGCCGGCTTAGCTGTACTTTTAGCATTAATCATTGGTTTTTTCATTTACAAAGAGCTCACACTCAATGCAGTATATAA
AGCATTGGTAGAAAGTGTAAATGGAACATCCGTTGTCATGCTACTGGTTGCGACGTCAGCTGTTTTGGGATTGTTTTTAA
CAGAACAGAAAGTACCTCAACAAATGGCTGCAGCAATTTTAAATATCTCGGACAATAAATATATCGTTTTAATGATGCTA
AATGTCATGTTATTTATTGTTGGTATGTTTTTACATGGCGCGGCGGCCATTATTTTAGTCGTCCCTATTGTTATGCCTCT
GATTACACAATTGGGCATTGATCCGATTCATTTTGGTATCATCTTAACGTTAAACATTGCAGTGGGTCAGCAAACACCAC
CGGTGGCAAGTGTATTAATCACAGCCTCATCTATCGCGAAAAAAGATATTTGGAGTGTCACTAAGGATAATGTTTGGTTT
ATTGTTGTATTATTAATTTCTTTAATGATGGTCACTTATATTCCTGCATTGACGGTTGGTATGGTGGACCTATTCTATTA
A

Upstream 100 bases:

>100_bases
CTCTCAGCAAAGGAAAAACCCAAGATGATGAGGAAATAGAACAAGCATTACGAGATGTGGACAGTAATGAAGGTATGAAG
ATAGCAAGGGAGAAATTACA

Downstream 100 bases:

>100_bases
TGATGAAACGAAATAAAGCCTGCCATCAGAGGAAGTTGATCGCAGGCTTTATTATTTTCAACCCAATTTGAACACAACAC
ACCGCAGAATGTGTTACAGG

Product: hypothetical protein

Products: NA

Alternate protein names: N-acetylneuraminic acid permease; N-acetylneuraminic acid transporter; Neu5Ac permease [H]

Number of amino acids: Translated: 426; Mature: 426

Protein sequence:

>426_residues
MIAFLVLIALVLLVMINVPIAVAIGIVSLIGMLITNSFDAIYNVALSVFDGASNFSLLAIPLFILAGALMNTGGISVRLI
NFVNALIGFVRGGLAMVNVGVSMIFAEISGSSVADVAALGSILIPAMKKRGYKSSFSAAVTSSSASLAVIIPPSLPMIIY
GAMADVSISKLFVAGLAAGGVASLGMFAVCYYYAVKYNLPREEHFSMSKLCTAFKNAFWALTLPVLILGGIISGFTTATE
AAGLAVLLALIIGFFIYKELTLNAVYKALVESVNGTSVVMLLVATSAVLGLFLTEQKVPQQMAAAILNISDNKYIVLMML
NVMLFIVGMFLHGAAAIILVVPIVMPLITQLGIDPIHFGIILTLNIAVGQQTPPVASVLITASSIAKKDIWSVTKDNVWF
IVVLLISLMMVTYIPALTVGMVDLFY

Sequences:

>Translated_426_residues
MIAFLVLIALVLLVMINVPIAVAIGIVSLIGMLITNSFDAIYNVALSVFDGASNFSLLAIPLFILAGALMNTGGISVRLI
NFVNALIGFVRGGLAMVNVGVSMIFAEISGSSVADVAALGSILIPAMKKRGYKSSFSAAVTSSSASLAVIIPPSLPMIIY
GAMADVSISKLFVAGLAAGGVASLGMFAVCYYYAVKYNLPREEHFSMSKLCTAFKNAFWALTLPVLILGGIISGFTTATE
AAGLAVLLALIIGFFIYKELTLNAVYKALVESVNGTSVVMLLVATSAVLGLFLTEQKVPQQMAAAILNISDNKYIVLMML
NVMLFIVGMFLHGAAAIILVVPIVMPLITQLGIDPIHFGIILTLNIAVGQQTPPVASVLITASSIAKKDIWSVTKDNVWF
IVVLLISLMMVTYIPALTVGMVDLFY
>Mature_426_residues
MIAFLVLIALVLLVMINVPIAVAIGIVSLIGMLITNSFDAIYNVALSVFDGASNFSLLAIPLFILAGALMNTGGISVRLI
NFVNALIGFVRGGLAMVNVGVSMIFAEISGSSVADVAALGSILIPAMKKRGYKSSFSAAVTSSSASLAVIIPPSLPMIIY
GAMADVSISKLFVAGLAAGGVASLGMFAVCYYYAVKYNLPREEHFSMSKLCTAFKNAFWALTLPVLILGGIISGFTTATE
AAGLAVLLALIIGFFIYKELTLNAVYKALVESVNGTSVVMLLVATSAVLGLFLTEQKVPQQMAAAILNISDNKYIVLMML
NVMLFIVGMFLHGAAAIILVVPIVMPLITQLGIDPIHFGIILTLNIAVGQQTPPVASVLITASSIAKKDIWSVTKDNVWF
IVVLLISLMMVTYIPALTVGMVDLFY

Specific function: Part of the tripartite ATP-independent periplasmic (TRAP) transport system siaPT involved in the uptake of sialic acid [H]

COG id: COG1593

COG function: function code G; TRAP-type C4-dicarboxylate transport system, large permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the TRAP transporter large permease family [H]

Homologues:

Organism=Escherichia coli, GI48994950, Length=372, Percent_Identity=37.6344086021505, Blast_Score=221, Evalue=5e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010656
- InterPro:   IPR007387
- InterPro:   IPR004681 [H]

Pfam domain/function: PF06808 DctM; PF04290 DctQ [H]

EC number: NA

Molecular weight: Translated: 44903; Mature: 44903

Theoretical pI: Translated: 8.58; Mature: 8.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIAFLVLIALVLLVMINVPIAVAIGIVSLIGMLITNSFDAIYNVALSVFDGASNFSLLAI
CHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCHHHHH
PLFILAGALMNTGGISVRLINFVNALIGFVRGGLAMVNVGVSMIFAEISGSSVADVAALG
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHH
SILIPAMKKRGYKSSFSAAVTSSSASLAVIIPPSLPMIIYGAMADVSISKLFVAGLAAGG
HHHHHHHHHCCCCCHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCH
VASLGMFAVCYYYAVKYNLPREEHFSMSKLCTAFKNAFWALTLPVLILGGIISGFTTATE
HHHHHHHHHHHHHHHHCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAGLAVLLALIIGFFIYKELTLNAVYKALVESVNGTSVVMLLVATSAVLGLFLTEQKVPQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
QMAAAILNISDNKYIVLMMLNVMLFIVGMFLHGAAAIILVVPIVMPLITQLGIDPIHFGI
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHEEE
ILTLNIAVGQQTPPVASVLITASSIAKKDIWSVTKDNVWFIVVLLISLMMVTYIPALTVG
EEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
MVDLFY
HHHHCC
>Mature Secondary Structure
MIAFLVLIALVLLVMINVPIAVAIGIVSLIGMLITNSFDAIYNVALSVFDGASNFSLLAI
CHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCHHHHH
PLFILAGALMNTGGISVRLINFVNALIGFVRGGLAMVNVGVSMIFAEISGSSVADVAALG
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHH
SILIPAMKKRGYKSSFSAAVTSSSASLAVIIPPSLPMIIYGAMADVSISKLFVAGLAAGG
HHHHHHHHHCCCCCHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCH
VASLGMFAVCYYYAVKYNLPREEHFSMSKLCTAFKNAFWALTLPVLILGGIISGFTTATE
HHHHHHHHHHHHHHHHCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAGLAVLLALIIGFFIYKELTLNAVYKALVESVNGTSVVMLLVATSAVLGLFLTEQKVPQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
QMAAAILNISDNKYIVLMMLNVMLFIVGMFLHGAAAIILVVPIVMPLITQLGIDPIHFGI
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHEEE
ILTLNIAVGQQTPPVASVLITASSIAKKDIWSVTKDNVWFIVVLLISLMMVTYIPALTVG
EEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
MVDLFY
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]