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The map label for this gene is murR [H]

Identifier: 15603442

GI number: 15603442

Start: 1786275

End: 1787135

Strand: Direct

Name: murR [H]

Synonym: PM1577

Alternate gene names: 15603442

Gene position: 1786275-1787135 (Clockwise)

Preceding gene: 15603439

Following gene: 15603443

Centisome position: 79.13

GC content: 40.42

Gene sequence:

>861_bases
ATGGGATTTTTAATTAAGCTGAAACATACTTATCCTTCGCTTTCCCCGAATGAACAGCGAATTGCAGACTTTATTTTAAA
ACACCCACACGAAGTAAAATCTTCTTCATCAAAAGCGTTAGCAAATCAAATTGCCGTGAGCCAATCTGCGATCATTAAGT
TTAGCCAGAAGTTAGGCGCGGATAAATTTAGTGATTTCAAACTGGCGATTAGTGAGGCATTGATTCGTCAAGAGACACAG
TCAGAACCGCGTGTCCATTTACACGACAGTATTACCGATAAAGACGATTTAAGTGAAATTGCAGAAAAACTGTTTGTAGA
AAAACAACAGGCATTGAAAGAAAGTTTAAGTTTGAACGCGATTCCTTATGTTGCGCGTGTGGTTGAGCAGCTCATGCAGG
CGAAACGTATTCAGTTGATGGGCATTGGGAATTCTGCGTTAGTAGCTAAAGATTTCTTTTATAAATTAACGAAAATTGGT
TTGCCCGTTGTGACCGAAACGGATACTCATGCTTCTTTAGCAATGAGCCAGAGTTTAACGCCACAAGATATTCTTTTTTT
GATTTCGTTTTCTGGACGCCACCGCGAAATTTTATTGGCGGCAGAGAATGCCAAAGCTCGCCAGATTAAAATAATCGCGT
TGACGGCGTTAACGACTAATCCATTGCATGAATTAGCAGATTATTTACTCTATTCGGTTGCCGATGAGTCCACGTTTCGT
AGTTCGTCCATTGCTTCACGAACAGCACAGCATGCAATAACAGACTTGTTATTTATGGGTATCTTGCAACAGAAAGAACA
TGCCAATGACCTGATTTTAGAAAGCCGTGCCTTGATTGGTCAACTGAACAAAGGACGTTAG

Upstream 100 bases:

>100_bases
TTTACTTTGGATTATTTTATTCCAAAATACCTCAATAATGGAGATTATTTATTCATTCTGTGAGCTTGCTCACTTTTTAT
TCTTATACGGGAGCTGCCCT

Downstream 100 bases:

>100_bases
GACAAGCCAAAAAGTGCGGTGTTTTTTTGGATTTTTTTGTTAAGTGCAAGAGGTATGTGTTCTTTAACAATTTCTTTACA
AGAAAGCAGGAGCATGATAA

Product: hypothetical protein

Products: NA

Alternate protein names: MurPQ operon repressor [H]

Number of amino acids: Translated: 286; Mature: 285

Protein sequence:

>286_residues
MGFLIKLKHTYPSLSPNEQRIADFILKHPHEVKSSSSKALANQIAVSQSAIIKFSQKLGADKFSDFKLAISEALIRQETQ
SEPRVHLHDSITDKDDLSEIAEKLFVEKQQALKESLSLNAIPYVARVVEQLMQAKRIQLMGIGNSALVAKDFFYKLTKIG
LPVVTETDTHASLAMSQSLTPQDILFLISFSGRHREILLAAENAKARQIKIIALTALTTNPLHELADYLLYSVADESTFR
SSSIASRTAQHAITDLLFMGILQQKEHANDLILESRALIGQLNKGR

Sequences:

>Translated_286_residues
MGFLIKLKHTYPSLSPNEQRIADFILKHPHEVKSSSSKALANQIAVSQSAIIKFSQKLGADKFSDFKLAISEALIRQETQ
SEPRVHLHDSITDKDDLSEIAEKLFVEKQQALKESLSLNAIPYVARVVEQLMQAKRIQLMGIGNSALVAKDFFYKLTKIG
LPVVTETDTHASLAMSQSLTPQDILFLISFSGRHREILLAAENAKARQIKIIALTALTTNPLHELADYLLYSVADESTFR
SSSIASRTAQHAITDLLFMGILQQKEHANDLILESRALIGQLNKGR
>Mature_285_residues
GFLIKLKHTYPSLSPNEQRIADFILKHPHEVKSSSSKALANQIAVSQSAIIKFSQKLGADKFSDFKLAISEALIRQETQS
EPRVHLHDSITDKDDLSEIAEKLFVEKQQALKESLSLNAIPYVARVVEQLMQAKRIQLMGIGNSALVAKDFFYKLTKIGL
PVVTETDTHASLAMSQSLTPQDILFLISFSGRHREILLAAENAKARQIKIIALTALTTNPLHELADYLLYSVADESTFRS
SSIASRTAQHAITDLLFMGILQQKEHANDLILESRALIGQLNKGR

Specific function: Represses the expression of the murPQ operon involved in the uptake and degradation of N-acetylmuramic acid (MurNAc). Binds to two adjacent inverted repeats within the operator region. MurNAc 6-phosphate, the substrate of murQ, is the specific inducer tha

COG id: COG1737

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI1788767, Length=264, Percent_Identity=42.0454545454545, Blast_Score=214, Evalue=4e-57,
Organism=Escherichia coli, GI87082130, Length=283, Percent_Identity=39.2226148409894, Blast_Score=191, Evalue=3e-50,
Organism=Escherichia coli, GI87082369, Length=286, Percent_Identity=25.5244755244755, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1788159, Length=263, Percent_Identity=28.8973384030418, Blast_Score=92, Evalue=3e-20,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022821
- InterPro:   IPR000281
- InterPro:   IPR001347
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01418 HTH_6; PF01380 SIS [H]

EC number: NA

Molecular weight: Translated: 31802; Mature: 31671

Theoretical pI: Translated: 9.25; Mature: 9.25

Prosite motif: PS51071 HTH_RPIR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGFLIKLKHTYPSLSPNEQRIADFILKHPHEVKSSSSKALANQIAVSQSAIIKFSQKLGA
CCEEEEEECCCCCCCCCHHHHHHHHHHCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCC
DKFSDFKLAISEALIRQETQSEPRVHLHDSITDKDDLSEIAEKLFVEKQQALKESLSLNA
CCCCHHHHHHHHHHHHHHHCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
IPYVARVVEQLMQAKRIQLMGIGNSALVAKDFFYKLTKIGLPVVTETDTHASLAMSQSLT
HHHHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHHCCCCEEECCCCHHHHHHHCCCC
PQDILFLISFSGRHREILLAAENAKARQIKIIALTALTTNPLHELADYLLYSVADESTFR
HHHEEEEEECCCCCEEEEEEECCCCCEEEEEEEEEEECCCHHHHHHHHHHHHHHCCHHHH
SSSIASRTAQHAITDLLFMGILQQKEHANDLILESRALIGQLNKGR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
GFLIKLKHTYPSLSPNEQRIADFILKHPHEVKSSSSKALANQIAVSQSAIIKFSQKLGA
CEEEEEECCCCCCCCCHHHHHHHHHHCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCC
DKFSDFKLAISEALIRQETQSEPRVHLHDSITDKDDLSEIAEKLFVEKQQALKESLSLNA
CCCCHHHHHHHHHHHHHHHCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
IPYVARVVEQLMQAKRIQLMGIGNSALVAKDFFYKLTKIGLPVVTETDTHASLAMSQSLT
HHHHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHHCCCCEEECCCCHHHHHHHCCCC
PQDILFLISFSGRHREILLAAENAKARQIKIIALTALTTNPLHELADYLLYSVADESTFR
HHHEEEEEECCCCCEEEEEEECCCCCEEEEEEEEEEECCCHHHHHHHHHHHHHHCCHHHH
SSSIASRTAQHAITDLLFMGILQQKEHANDLILESRALIGQLNKGR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA