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The map label for this gene is comM [H]

Identifier: 15603375

GI number: 15603375

Start: 1708182

End: 1709711

Strand: Reverse

Name: comM [H]

Synonym: PM1510

Alternate gene names: 15603375

Gene position: 1709711-1708182 (Counterclockwise)

Preceding gene: 15603376

Following gene: 15603371

Centisome position: 75.74

GC content: 44.71

Gene sequence:

>1530_bases
ATGTCACTTGCAATTGTTTATAGTCGCGCCTCAATGGGCGTACAAGCCCCTTTAGTCACCATTGAGGTGCATTTCAGTAA
TGGTAAACCGCAATTCAACTTAGTCGGCTTACCCGAAAAAACCGTCAAAGAAGCACAAGATCGCGTACGCAGTGCCTTGC
TCAATGCTCAATTTAAATACCCTGCTAAACGGATCACGGTCAATCTCGCCCCCGCCGATTTACCCAAAGAAGGCGGACGT
TTTGATTTACCGATCGCCATTGGTATGCTCGCCGCTTCTGGTCAAATTGATCCACAAAAGTTACAACAATTTGAATTTGT
GGGTGAGTTAGCGCTAACCGGTGATTTACGTGCAGTACATGGCGTCATCCCCGCGATCCTTGCTGCACAAAAAGCCAAGC
GAAAATTGATTATCGCCAGTCAAAATGCCAATGAAGCCTCGTTAGTTTCCCAGCAAGACACCTATTTTGCGCAAGATTTA
TTAGAAGTCGTCAATTTCCTCAATGATCATACCACGTTACCTTTAGCCTCAGAACTGCCCACACAACATGATCCAGCCCT
TTTAGCAACAACACAAAAAGATTTAACCGATATTATCGGACAATCCCATGCTAAACGCGCCTTAACTATTGCTGCCGCAG
GACAACATAATCTGCTTTTTTTGGGTCCGCCCGGTACAGGAAAGACCATGCTCGCCAGCCGATTAACTACATTGTTACCG
GAAATGAACGATCAAGAAGCCATTGAAACCGCCGCAGTGACAAGCCTTGTTCATCATGAATTGAATTTTCATAATTGGAA
ACAACGCCCATTTCGTGCCCCTCATCACAGCGCTTCAACACCGGCTTTAGTAGGGGGCGGCACCATACCCAAACCCGGTG
AAATTTCGCTCGCACACAATGGGGTGTTATTTCTCGATGAGTTACCAGAATTTGAACGTAAAGTATTAGATGCCTTACGT
CAACCTTTGGAAAGTGGTGAAATTATCATTTCGCGTGCCAATGCAAAAATTCAATTTCCTGCTCGTTTTCAATTAATTGC
CGCCATGAATCCTAGCCCAACAGGACATTATCAAGGTACTCACAATCGCACCTCACCACAACAAATCTTGCGTTATCTCA
ATCGCTTATCCGGTCCATTTTTAGATCGCTTTGATTTGTCAATCGAAGTCCCTTTACTACCCAAAGGCGCGTTACAACAG
CAAACGGATCGGGGCGAAAGTAGCGCACAAGTGAGGGAAAAAGTATTAAAAGTACGCGACATACAACTGGCTCGCGCGGG
GAAAATTAATGCTTATTTGACCAGTAAAGAAATTGAGCGAGACTGTAAGATCAGTGATCAAGATGCGTTATTTTTAGAAA
ATGCCTTAGCTAAATTGGGATTATCCGTGCGCGCCTATCATCGTATTTTAAAAGTAGCACGCACCATTGCAGACTTAAAT
AATGAACGCCAAATTCAACAATGCCACCTCGCCGAAGCACTGGGTTATCGGGCGATGGATAGGTTGTTACAGAAGTTATC
TGCGATGTAG

Upstream 100 bases:

>100_bases
GTTTCTGCGATCTAGATCGTAAAAAAGTGCGTTCTTCCTGCCAAAGGAAACGCACTTTTTTATTATCCAGCGGTTTTCTT
TTTTATCAGTGGAATGAACG

Downstream 100 bases:

>100_bases
GCTCGTGCGGTGACAAAACAGCGTTAAAAAGCACCGCACTTGTTTTGAAAACGCTATTGGCACACAATATTCGTCAATAA
CGTGACTTTTTCTTTTAAAT

Product: ComM

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 509; Mature: 508

Protein sequence:

>509_residues
MSLAIVYSRASMGVQAPLVTIEVHFSNGKPQFNLVGLPEKTVKEAQDRVRSALLNAQFKYPAKRITVNLAPADLPKEGGR
FDLPIAIGMLAASGQIDPQKLQQFEFVGELALTGDLRAVHGVIPAILAAQKAKRKLIIASQNANEASLVSQQDTYFAQDL
LEVVNFLNDHTTLPLASELPTQHDPALLATTQKDLTDIIGQSHAKRALTIAAAGQHNLLFLGPPGTGKTMLASRLTTLLP
EMNDQEAIETAAVTSLVHHELNFHNWKQRPFRAPHHSASTPALVGGGTIPKPGEISLAHNGVLFLDELPEFERKVLDALR
QPLESGEIIISRANAKIQFPARFQLIAAMNPSPTGHYQGTHNRTSPQQILRYLNRLSGPFLDRFDLSIEVPLLPKGALQQ
QTDRGESSAQVREKVLKVRDIQLARAGKINAYLTSKEIERDCKISDQDALFLENALAKLGLSVRAYHRILKVARTIADLN
NERQIQQCHLAEALGYRAMDRLLQKLSAM

Sequences:

>Translated_509_residues
MSLAIVYSRASMGVQAPLVTIEVHFSNGKPQFNLVGLPEKTVKEAQDRVRSALLNAQFKYPAKRITVNLAPADLPKEGGR
FDLPIAIGMLAASGQIDPQKLQQFEFVGELALTGDLRAVHGVIPAILAAQKAKRKLIIASQNANEASLVSQQDTYFAQDL
LEVVNFLNDHTTLPLASELPTQHDPALLATTQKDLTDIIGQSHAKRALTIAAAGQHNLLFLGPPGTGKTMLASRLTTLLP
EMNDQEAIETAAVTSLVHHELNFHNWKQRPFRAPHHSASTPALVGGGTIPKPGEISLAHNGVLFLDELPEFERKVLDALR
QPLESGEIIISRANAKIQFPARFQLIAAMNPSPTGHYQGTHNRTSPQQILRYLNRLSGPFLDRFDLSIEVPLLPKGALQQ
QTDRGESSAQVREKVLKVRDIQLARAGKINAYLTSKEIERDCKISDQDALFLENALAKLGLSVRAYHRILKVARTIADLN
NERQIQQCHLAEALGYRAMDRLLQKLSAM
>Mature_508_residues
SLAIVYSRASMGVQAPLVTIEVHFSNGKPQFNLVGLPEKTVKEAQDRVRSALLNAQFKYPAKRITVNLAPADLPKEGGRF
DLPIAIGMLAASGQIDPQKLQQFEFVGELALTGDLRAVHGVIPAILAAQKAKRKLIIASQNANEASLVSQQDTYFAQDLL
EVVNFLNDHTTLPLASELPTQHDPALLATTQKDLTDIIGQSHAKRALTIAAAGQHNLLFLGPPGTGKTMLASRLTTLLPE
MNDQEAIETAAVTSLVHHELNFHNWKQRPFRAPHHSASTPALVGGGTIPKPGEISLAHNGVLFLDELPEFERKVLDALRQ
PLESGEIIISRANAKIQFPARFQLIAAMNPSPTGHYQGTHNRTSPQQILRYLNRLSGPFLDRFDLSIEVPLLPKGALQQQ
TDRGESSAQVREKVLKVRDIQLARAGKINAYLTSKEIERDCKISDQDALFLENALAKLGLSVRAYHRILKVARTIADLNN
ERQIQQCHLAEALGYRAMDRLLQKLSAM

Specific function: Induced during competence development. Not needed for DNA uptake. May be involved in a recombination step [H]

COG id: COG0606

COG function: function code O; Predicted ATPase with chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily [H]

Homologues:

Organism=Escherichia coli, GI145693202, Length=509, Percent_Identity=58.9390962671906, Blast_Score=611, Evalue=1e-176,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR001208
- InterPro:   IPR004482
- InterPro:   IPR000523
- InterPro:   IPR020568 [H]

Pfam domain/function: PF01078 Mg_chelatase [H]

EC number: NA

Molecular weight: Translated: 55941; Mature: 55810

Theoretical pI: Translated: 9.56; Mature: 9.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLAIVYSRASMGVQAPLVTIEVHFSNGKPQFNLVGLPEKTVKEAQDRVRSALLNAQFKY
CCEEEEEECCCCCCCCCEEEEEEEECCCCCCEEEECCCHHHHHHHHHHHHHHHHCCCCCC
PAKRITVNLAPADLPKEGGRFDLPIAIGMLAASGQIDPQKLQQFEFVGELALTGDLRAVH
CCEEEEEEECCCCCCCCCCCEECHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCHHHHH
GVIPAILAAQKAKRKLIIASQNANEASLVSQQDTYFAQDLLEVVNFLNDHTTLPLASELP
HHHHHHHHHHHHCCEEEEEECCCCCHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCHHHCC
TQHDPALLATTQKDLTDIIGQSHAKRALTIAAAGQHNLLFLGPPGTGKTMLASRLTTLLP
CCCCCEEEEECHHHHHHHHCCHHCCCEEEEEECCCCCEEEECCCCCCHHHHHHHHHHHCC
EMNDQEAIETAAVTSLVHHELNFHNWKQRPFRAPHHSASTPALVGGGTIPKPGEISLAHN
CCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCEEEECC
GVLFLDELPEFERKVLDALRQPLESGEIIISRANAKIQFPARFQLIAAMNPSPTGHYQGT
CEEEECCCCHHHHHHHHHHHCCCCCCCEEEEECCCEEECCCEEEEEEECCCCCCCCCCCC
HNRTSPQQILRYLNRLSGPFLDRFDLSIEVPLLPKGALQQQTDRGESSAQVREKVLKVRD
CCCCCHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCHHHHHHCCCCHHHHHHHHHHHHHH
IQLARAGKINAYLTSKEIERDCKISDQDALFLENALAKLGLSVRAYHRILKVARTIADLN
HHHHCCCCCEEEEEHHHHHCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCC
NERQIQQCHLAEALGYRAMDRLLQKLSAM
CCHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SLAIVYSRASMGVQAPLVTIEVHFSNGKPQFNLVGLPEKTVKEAQDRVRSALLNAQFKY
CEEEEEECCCCCCCCCEEEEEEEECCCCCCEEEECCCHHHHHHHHHHHHHHHHCCCCCC
PAKRITVNLAPADLPKEGGRFDLPIAIGMLAASGQIDPQKLQQFEFVGELALTGDLRAVH
CCEEEEEEECCCCCCCCCCCEECHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCHHHHH
GVIPAILAAQKAKRKLIIASQNANEASLVSQQDTYFAQDLLEVVNFLNDHTTLPLASELP
HHHHHHHHHHHHCCEEEEEECCCCCHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCHHHCC
TQHDPALLATTQKDLTDIIGQSHAKRALTIAAAGQHNLLFLGPPGTGKTMLASRLTTLLP
CCCCCEEEEECHHHHHHHHCCHHCCCEEEEEECCCCCEEEECCCCCCHHHHHHHHHHHCC
EMNDQEAIETAAVTSLVHHELNFHNWKQRPFRAPHHSASTPALVGGGTIPKPGEISLAHN
CCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCEEEECC
GVLFLDELPEFERKVLDALRQPLESGEIIISRANAKIQFPARFQLIAAMNPSPTGHYQGT
CEEEECCCCHHHHHHHHHHHCCCCCCCEEEEECCCEEECCCEEEEEEECCCCCCCCCCCC
HNRTSPQQILRYLNRLSGPFLDRFDLSIEVPLLPKGALQQQTDRGESSAQVREKVLKVRD
CCCCCHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCHHHHHHCCCCHHHHHHHHHHHHHH
IQLARAGKINAYLTSKEIERDCKISDQDALFLENALAKLGLSVRAYHRILKVARTIADLN
HHHHCCCCCEEEEEHHHHHCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCC
NERQIQQCHLAEALGYRAMDRLLQKLSAM
CCHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800; 9457884 [H]