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The map label for this gene is glpA [H]

Identifier: 15603307

GI number: 15603307

Start: 1627590

End: 1629281

Strand: Reverse

Name: glpA [H]

Synonym: PM1442

Alternate gene names: 15603307

Gene position: 1629281-1627590 (Counterclockwise)

Preceding gene: 15603312

Following gene: 15603306

Centisome position: 72.17

GC content: 46.81

Gene sequence:

>1692_bases
ATGACAATATCACCTCAGATGTATAAAAGTACCGCAGATACAAGCCCGATGACGACGGATGTGATTATTATTGGTGGTGG
TGCCACCGGTGCCGGGATTGCACGAGATTGCGCGCTGCGTGGTGTGAACTGTGTCTTATTAGAACGGCGGGATATTGCAA
CAGGCGCCACAGGACGGAATCATGGCTTGTTACACAGTGGCGCGAGATATGCGGTAAACGATCCAGAATCTGCCAAAGAA
TGTATTGAAGAGAATAAAATTTTACGTCGTATTGCCCGCCATTGTGTTGATGAAACAGAAGGCTTATTTATTACCCTCCC
CGAAGATGATCTGTCTTACCAAAAGCAATTTATCCAAAGCTGTACGCAGGCTGGCATAGACGCCATTGCGATTGATCCTG
ATCTTGCGAAACATTTAGAACCTTCTGTTAATCCTGATTTAGTCGGTGCGGTCGTAGTGCCAGACGGTTCTATTGATCCT
TTTCGCTTAACGGCATCCAATATGCTCGATGCAACGGAAAATGGCGCGCGTATTTTTACCTACTGTGAAGTGAAAAACCT
CATTCAAGAAGGCGGTCGTGTCATTGGTGTGAGCGTTTACGATCATAAATATAAAATTAATCGTCAGTTTTTTGCCCCAG
TGGTGGTCAATGCCAGTGGGATTTGGGGACAAGGTATTGCCGCTTATGCAGATTTGAACATTCGTATGTTCCCAGCGAAA
GGAGCATTACTGGTGATGGGGCACCGTATTAATAAAATGGTGATTAACCGCTGTCGTAAACCTGCCGATGCGGATATTTT
GGTGCCGGGTGATACTATTTGTGTGATCGGAACGACATCGAGCCGTATTCCTTATGATCAAATTGACAATATGGTGGTCA
CCCCTGAAGAAGTGGATATTTTATTCCGCGAAGGTGAAAAGTTGGCGCCTTCATTACGTCATACTCGTGTATTACGGGCT
TATGCCGGAGTACGACCGCTCGTCGCCACCGATGACGATCCTTCTGGTCGTAACGTTAGCCGTGGCATTGTGTTGCTTGA
TCATGCAGAAAGGGATGGGTTGGAAGGCTTTGTCACCATTACGGGTGGAAAACTGATGACTTATCGCTTAATGGCTGAAT
GGGCAACTGACTTGGTATGTAAAAAATTGAATAAACATGCTGAGTGTGTGACAGCAACCCAGCCCTTACCCGGCTCAAGT
GAAAGCCGTTTAGAAACGAATAAACGGGTTATTTCATTACCGAGTACGATTCGCTATTCTGCGGTTTATCGGCATGGCTC
ACGTGCAACGCGATTATTACACTCAGAACGTCTTGACCGCTCTTTAGTGTGCGAATGTGAGGCAGTGACCGCTGGGGAAG
TGCGTTATGCGGTTGATGAACTGAGTGTCAATAATTTAGTCGATTTACGCCGCCGTACACGTGTGGGCATGGGGACTTGT
CAGGCAGAGTTGTGTGCCTGTCGTGCAGCTGGCTTAATGGCACGTTTTGGGGTAGCGACACCACGTCAATCAACCACACA
GCTTGCCTCTTTTATGGAAGAGCGTTGGCGTGGTATTGAACCAATTGCATGGGGCGAAGCCATGCGAGAAGCGGATTTTA
CCTCATGGGTTTATTACAGCTTACTCGGTTTAAATGATGTAAAACCGCTTGAACAACAAGCACAGCAAGGGACGGATGAC
AATGAATTTTGA

Upstream 100 bases:

>100_bases
TTTTTCAATCAAATGATTGTTTGTTTGTGCGTGTTTAGCCTAAAATGACAGCAGAAGTAATGTTTTTTTGATTGTTTTTT
GTTTATGTGGGAGAGGAAAG

Downstream 100 bases:

>100_bases
TGTCGTAATTATTGGCGGTGGTCTTGCAGGTTTAACATGTGGCATCGCGTTACAAACACAAGGCAAGCAGTGCGTGATCA
TTAACAATGGTCAGGCCGCG

Product: sn-glycerol-3-phosphate dehydrogenase subunit A

Products: NA

Alternate protein names: G-3-P dehydrogenase [H]

Number of amino acids: Translated: 563; Mature: 562

Protein sequence:

>563_residues
MTISPQMYKSTADTSPMTTDVIIIGGGATGAGIARDCALRGVNCVLLERRDIATGATGRNHGLLHSGARYAVNDPESAKE
CIEENKILRRIARHCVDETEGLFITLPEDDLSYQKQFIQSCTQAGIDAIAIDPDLAKHLEPSVNPDLVGAVVVPDGSIDP
FRLTASNMLDATENGARIFTYCEVKNLIQEGGRVIGVSVYDHKYKINRQFFAPVVVNASGIWGQGIAAYADLNIRMFPAK
GALLVMGHRINKMVINRCRKPADADILVPGDTICVIGTTSSRIPYDQIDNMVVTPEEVDILFREGEKLAPSLRHTRVLRA
YAGVRPLVATDDDPSGRNVSRGIVLLDHAERDGLEGFVTITGGKLMTYRLMAEWATDLVCKKLNKHAECVTATQPLPGSS
ESRLETNKRVISLPSTIRYSAVYRHGSRATRLLHSERLDRSLVCECEAVTAGEVRYAVDELSVNNLVDLRRRTRVGMGTC
QAELCACRAAGLMARFGVATPRQSTTQLASFMEERWRGIEPIAWGEAMREADFTSWVYYSLLGLNDVKPLEQQAQQGTDD
NEF

Sequences:

>Translated_563_residues
MTISPQMYKSTADTSPMTTDVIIIGGGATGAGIARDCALRGVNCVLLERRDIATGATGRNHGLLHSGARYAVNDPESAKE
CIEENKILRRIARHCVDETEGLFITLPEDDLSYQKQFIQSCTQAGIDAIAIDPDLAKHLEPSVNPDLVGAVVVPDGSIDP
FRLTASNMLDATENGARIFTYCEVKNLIQEGGRVIGVSVYDHKYKINRQFFAPVVVNASGIWGQGIAAYADLNIRMFPAK
GALLVMGHRINKMVINRCRKPADADILVPGDTICVIGTTSSRIPYDQIDNMVVTPEEVDILFREGEKLAPSLRHTRVLRA
YAGVRPLVATDDDPSGRNVSRGIVLLDHAERDGLEGFVTITGGKLMTYRLMAEWATDLVCKKLNKHAECVTATQPLPGSS
ESRLETNKRVISLPSTIRYSAVYRHGSRATRLLHSERLDRSLVCECEAVTAGEVRYAVDELSVNNLVDLRRRTRVGMGTC
QAELCACRAAGLMARFGVATPRQSTTQLASFMEERWRGIEPIAWGEAMREADFTSWVYYSLLGLNDVKPLEQQAQQGTDD
NEF
>Mature_562_residues
TISPQMYKSTADTSPMTTDVIIIGGGATGAGIARDCALRGVNCVLLERRDIATGATGRNHGLLHSGARYAVNDPESAKEC
IEENKILRRIARHCVDETEGLFITLPEDDLSYQKQFIQSCTQAGIDAIAIDPDLAKHLEPSVNPDLVGAVVVPDGSIDPF
RLTASNMLDATENGARIFTYCEVKNLIQEGGRVIGVSVYDHKYKINRQFFAPVVVNASGIWGQGIAAYADLNIRMFPAKG
ALLVMGHRINKMVINRCRKPADADILVPGDTICVIGTTSSRIPYDQIDNMVVTPEEVDILFREGEKLAPSLRHTRVLRAY
AGVRPLVATDDDPSGRNVSRGIVLLDHAERDGLEGFVTITGGKLMTYRLMAEWATDLVCKKLNKHAECVTATQPLPGSSE
SRLETNKRVISLPSTIRYSAVYRHGSRATRLLHSERLDRSLVCECEAVTAGEVRYAVDELSVNNLVDLRRRTRVGMGTCQ
AELCACRAAGLMARFGVATPRQSTTQLASFMEERWRGIEPIAWGEAMREADFTSWVYYSLLGLNDVKPLEQQAQQGTDDN
EF

Specific function: Conversion Of Glycerol 3-Phosphate To Dihydroxyacetone. Uses Fumarate Or Nitrate As Electron Acceptor. [C]

COG id: COG0578

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein. Note=Loosely bound to the cytoplasmic membrane often occurring in vesicles associated with fumarate reductase (By similarity) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI285002233, Length=521, Percent_Identity=27.447216890595, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI285002231, Length=521, Percent_Identity=27.447216890595, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI197927446, Length=298, Percent_Identity=24.1610738255034, Blast_Score=70, Evalue=6e-12,
Organism=Homo sapiens, GI21361378, Length=298, Percent_Identity=24.1610738255034, Blast_Score=70, Evalue=6e-12,
Organism=Escherichia coli, GI1788574, Length=510, Percent_Identity=70.1960784313725, Blast_Score=740, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17509253, Length=412, Percent_Identity=27.9126213592233, Blast_Score=86, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI115534726, Length=406, Percent_Identity=25.615763546798, Blast_Score=76, Evalue=6e-14,
Organism=Drosophila melanogaster, GI161077125, Length=435, Percent_Identity=28.0459770114943, Blast_Score=93, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24653942, Length=435, Percent_Identity=28.0459770114943, Blast_Score=93, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24653944, Length=435, Percent_Identity=28.0459770114943, Blast_Score=93, Evalue=4e-19,
Organism=Drosophila melanogaster, GI20130025, Length=435, Percent_Identity=28.0459770114943, Blast_Score=93, Evalue=4e-19,
Organism=Drosophila melanogaster, GI20130091, Length=245, Percent_Identity=31.8367346938775, Blast_Score=92, Evalue=9e-19,
Organism=Drosophila melanogaster, GI24586295, Length=389, Percent_Identity=23.9074550128535, Blast_Score=66, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007419
- InterPro:   IPR006076
- InterPro:   IPR017752
- InterPro:   IPR000447 [H]

Pfam domain/function: PF01266 DAO; PF04324 Fer2_BFD [H]

EC number: =1.1.5.3 [H]

Molecular weight: Translated: 61847; Mature: 61716

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: PS00977 FAD_G3PDH_1 ; PS00978 FAD_G3PDH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTISPQMYKSTADTSPMTTDVIIIGGGATGAGIARDCALRGVNCVLLERRDIATGATGRN
CCCCCHHHHCCCCCCCCEEEEEEECCCCCCCCHHHHHHHCCCCEEEEECCCCCCCCCCCC
HGLLHSGARYAVNDPESAKECIEENKILRRIARHCVDETEGLFITLPEDDLSYQKQFIQS
CCCEECCCCEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHH
CTQAGIDAIAIDPDLAKHLEPSVNPDLVGAVVVPDGSIDPFRLTASNMLDATENGARIFT
HHHCCCCEEEECHHHHHHCCCCCCCCCEEEEEECCCCCCCEEEEHHHHHCCCCCCCEEEE
YCEVKNLIQEGGRVIGVSVYDHKYKINRQFFAPVVVNASGIWGQGIAAYADLNIRMFPAK
EHHHHHHHHCCCEEEEEEEECCEEEECCEEECEEEEECCCCCCCCEEEEEECEEEEECCC
GALLVMGHRINKMVINRCRKPADADILVPGDTICVIGTTSSRIPYDQIDNMVVTPEEVDI
CEEEEECCHHHHHHHHHCCCCCCCEEEECCCEEEEEECCCCCCCHHHHCCEEECCHHHHH
LFREGEKLAPSLRHTRVLRAYAGVRPLVATDDDPSGRNVSRGIVLLDHAERDGLEGFVTI
EECCCCHHCCHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCEEEEECCCCCCCCEEEEE
TGGKLMTYRLMAEWATDLVCKKLNKHAECVTATQPLPGSSESRLETNKRVISLPSTIRYS
ECCCEEHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHCCCEEEECCCHHHHH
AVYRHGSRATRLLHSERLDRSLVCECEAVTAGEVRYAVDELSVNNLVDLRRRTRVGMGTC
HHHHCCHHHHHHHHHHHCCCHHEEEEECCCCCCHHHHHHHHCHHHHHHHHHHHHCCCCHH
QAELCACRAAGLMARFGVATPRQSTTQLASFMEERWRGIEPIAWGEAMREADFTSWVYYS
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCHHHHHHH
LLGLNDVKPLEQQAQQGTDDNEF
HHCCCCCCHHHHHHHCCCCCCCC
>Mature Secondary Structure 
TISPQMYKSTADTSPMTTDVIIIGGGATGAGIARDCALRGVNCVLLERRDIATGATGRN
CCCCHHHHCCCCCCCCEEEEEEECCCCCCCCHHHHHHHCCCCEEEEECCCCCCCCCCCC
HGLLHSGARYAVNDPESAKECIEENKILRRIARHCVDETEGLFITLPEDDLSYQKQFIQS
CCCEECCCCEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHH
CTQAGIDAIAIDPDLAKHLEPSVNPDLVGAVVVPDGSIDPFRLTASNMLDATENGARIFT
HHHCCCCEEEECHHHHHHCCCCCCCCCEEEEEECCCCCCCEEEEHHHHHCCCCCCCEEEE
YCEVKNLIQEGGRVIGVSVYDHKYKINRQFFAPVVVNASGIWGQGIAAYADLNIRMFPAK
EHHHHHHHHCCCEEEEEEEECCEEEECCEEECEEEEECCCCCCCCEEEEEECEEEEECCC
GALLVMGHRINKMVINRCRKPADADILVPGDTICVIGTTSSRIPYDQIDNMVVTPEEVDI
CEEEEECCHHHHHHHHHCCCCCCCEEEECCCEEEEEECCCCCCCHHHHCCEEECCHHHHH
LFREGEKLAPSLRHTRVLRAYAGVRPLVATDDDPSGRNVSRGIVLLDHAERDGLEGFVTI
EECCCCHHCCHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCEEEEECCCCCCCCEEEEE
TGGKLMTYRLMAEWATDLVCKKLNKHAECVTATQPLPGSSESRLETNKRVISLPSTIRYS
ECCCEEHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHCCCEEEECCCHHHHH
AVYRHGSRATRLLHSERLDRSLVCECEAVTAGEVRYAVDELSVNNLVDLRRRTRVGMGTC
HHHHCCHHHHHHHHHHHCCCHHEEEEECCCCCCHHHHHHHHCHHHHHHHHHHHHCCCCHH
QAELCACRAAGLMARFGVATPRQSTTQLASFMEERWRGIEPIAWGEAMREADFTSWVYYS
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCHHHHHHH
LLGLNDVKPLEQQAQQGTDDNEF
HHCCCCCCHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]