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The map label for this gene is dod_1 [H]

Identifier: 15603145

GI number: 15603145

Start: 1472707

End: 1473396

Strand: Direct

Name: dod_1 [H]

Synonym: PM1280

Alternate gene names: 15603145

Gene position: 1472707-1473396 (Clockwise)

Preceding gene: 15603144

Following gene: 15603147

Centisome position: 65.24

GC content: 42.46

Gene sequence:

>690_bases
GTGGATAAAAAACAGCTAATTCAACAATTAAAAACACAACCGATAAGCGTGGGCATTTTGGCTTCTGATTGGTTGAAATT
CGCCGATACACTCACGACTTTATCGCGACATCATTTGCGTTTGTTGCACTTTGATATTGGAGATGGGCAATTTTCGCCTT
TCTTTACTGTGGGTGCGCTTGCGGTGAAACAATTCCCGTCCCCTTGGCTTAAAGATGTACATTTAATGGTAAACGATCCT
TTTCATGTAGCTAAAGCCTGTGCTGATGCGGGGGCGGATATCATTACATTGCAAGTGGAACAGACAGACTGTCTGGCTGA
AACGATAAGTTATTTACGGGAACATTATCCCGATTTACTTATCGGACTGACACTTTGTCCTGATACAGAGATTGATTTGT
TAACCCCTTATTTAGCGCAAGTCGATTTAATTCAGATTCTGACCCTTGATCCGAGAACGGGTGTAAAAGCGGAAACAGAT
GCCGTCATTAAACGTATTACGCGAATAAGTAATATGTTAGGGGAGCATCGCGATCAAAAATTGATTTCTGTAGATGGTTC
AATGAATTTAGCACTGGCAAGCCAATTATTTCCTTTGGGGATTGATTGGGTCGTCTCGGGTAGTGCGTTGTTTAGCCAAG
CAGATGTAGATGCCACGTTATCGGAATGGAAGACCCATCTCTGTCGCTAA

Upstream 100 bases:

>100_bases
CATTACCATCGTTGTGTCGCAGAATTAGAACCTTTGATGACGGGGGCGAGAAGTAAAAAACTGTTTGATTGGGTCATGCC
TGAGAACTTAACGAATGAAT

Downstream 100 bases:

>100_bases
TCAGTGTTTTGCGTATTTTTCTGCACCTAGTTTTAGGTGCAGATCATGTTATTTATAACGCCGCTTTAATCTCACCAAGC
CTTCACTCATAAATAAAATC

Product: ribulose-phosphate 3-epimerase

Products: fructose-6-phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 229; Mature: 229

Protein sequence:

>229_residues
MDKKQLIQQLKTQPISVGILASDWLKFADTLTTLSRHHLRLLHFDIGDGQFSPFFTVGALAVKQFPSPWLKDVHLMVNDP
FHVAKACADAGADIITLQVEQTDCLAETISYLREHYPDLLIGLTLCPDTEIDLLTPYLAQVDLIQILTLDPRTGVKAETD
AVIKRITRISNMLGEHRDQKLISVDGSMNLALASQLFPLGIDWVVSGSALFSQADVDATLSEWKTHLCR

Sequences:

>Translated_229_residues
MDKKQLIQQLKTQPISVGILASDWLKFADTLTTLSRHHLRLLHFDIGDGQFSPFFTVGALAVKQFPSPWLKDVHLMVNDP
FHVAKACADAGADIITLQVEQTDCLAETISYLREHYPDLLIGLTLCPDTEIDLLTPYLAQVDLIQILTLDPRTGVKAETD
AVIKRITRISNMLGEHRDQKLISVDGSMNLALASQLFPLGIDWVVSGSALFSQADVDATLSEWKTHLCR
>Mature_229_residues
MDKKQLIQQLKTQPISVGILASDWLKFADTLTTLSRHHLRLLHFDIGDGQFSPFFTVGALAVKQFPSPWLKDVHLMVNDP
FHVAKACADAGADIITLQVEQTDCLAETISYLREHYPDLLIGLTLCPDTEIDLLTPYLAQVDLIQILTLDPRTGVKAETD
AVIKRITRISNMLGEHRDQKLISVDGSMNLALASQLFPLGIDWVVSGSALFSQADVDATLSEWKTHLCR

Specific function: D-ALLOSE METABOLISM. ESSENTIAL FOR THIS PATHWAY. [C]

COG id: COG0036

COG function: function code G; Pentose-5-phosphate-3-epimerase

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribulose-phosphate 3-epimerase family [H]

Homologues:

Organism=Homo sapiens, GI40385883, Length=211, Percent_Identity=26.0663507109005, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI219879828, Length=211, Percent_Identity=25.1184834123223, Blast_Score=67, Evalue=1e-11,
Organism=Escherichia coli, GI1790523, Length=205, Percent_Identity=31.219512195122, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1789788, Length=223, Percent_Identity=23.7668161434978, Blast_Score=82, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24586301, Length=213, Percent_Identity=25.3521126760563, Blast_Score=68, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR000056
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00834 Ribul_P_3_epim [H]

EC number: 5.1.3.- [C]

Molecular weight: Translated: 25462; Mature: 25462

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKKQLIQQLKTQPISVGILASDWLKFADTLTTLSRHHLRLLHFDIGDGQFSPFFTVGAL
CCHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCHHHHHHHH
AVKQFPSPWLKDVHLMVNDPFHVAKACADAGADIITLQVEQTDCLAETISYLREHYPDLL
HHHHCCCHHHHHEEHEECCCHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHCCHHE
IGLTLCPDTEIDLLTPYLAQVDLIQILTLDPRTGVKAETDAVIKRITRISNMLGEHRDQK
EEEEECCCCCHHHHHHHHHHHHHHHEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCE
LISVDGSMNLALASQLFPLGIDWVVSGSALFSQADVDATLSEWKTHLCR
EEEECCCCCHHHHHHHCCCCHHHEECCHHHHHHCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MDKKQLIQQLKTQPISVGILASDWLKFADTLTTLSRHHLRLLHFDIGDGQFSPFFTVGAL
CCHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCHHHHHHHH
AVKQFPSPWLKDVHLMVNDPFHVAKACADAGADIITLQVEQTDCLAETISYLREHYPDLL
HHHHCCCHHHHHEEHEECCCHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHCCHHE
IGLTLCPDTEIDLLTPYLAQVDLIQILTLDPRTGVKAETDAVIKRITRISNMLGEHRDQK
EEEEECCCCCHHHHHHHHHHHHHHHEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCE
LISVDGSMNLALASQLFPLGIDWVVSGSALFSQADVDATLSEWKTHLCR
EEEECCCCCHHHHHHHCCCCHHHEECCHHHHHHCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: D-allulose-6-phosphate [C]

Specific reaction: D-allulose-6-phosphate = fructose-6-phosphate [C]

General reaction: Isomerases; Racemases and Epimerases; Acting on Carbohydrates and Derivatives [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA