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The map label for this gene is lsrG [H]

Identifier: 15603144

GI number: 15603144

Start: 1472400

End: 1472714

Strand: Direct

Name: lsrG [H]

Synonym: PM1279

Alternate gene names: 15603144

Gene position: 1472400-1472714 (Clockwise)

Preceding gene: 15603143

Following gene: 15603145

Centisome position: 65.22

GC content: 39.68

Gene sequence:

>315_bases
ATGTTTGCAATGTTAGTGGAAATCAATATTAAAGAAGGTAAAGAACAAGAATTCCTAGAGGTTTTTGCACGCAACCATAT
TGGTACAAGACAAGAACCGGGTAACTTGCGTTTTGATGTATTACGCGATCCTGAAATCAAAACACGTTTTTATGCTTATG
AAGTGTACGTCAATGAACAAGCCTTAGAGGCGCATCGTCAAACGGCACATTACCATCGTTGTGTCGCAGAATTAGAACCT
TTGATGACGGGGGCGAGAAGTAAAAAACTGTTTGATTGGGTCATGCCTGAGAACTTAACGAATGAATGTGGATAA

Upstream 100 bases:

>100_bases
GAAAAATAACGCGTGAATAAGCCTATCAAAGAGCGGTTGAAATTCGGTGAAAACCAACCGCTCTTTTCATGATGTTTTTC
TTTATGTTAGGGAGTCGACT

Downstream 100 bases:

>100_bases
AAAACAGCTAATTCAACAATTAAAAACACAACCGATAAGCGTGGGCATTTTGGCTTCTGATTGGTTGAAATTCGCCGATA
CACTCACGACTTTATCGCGA

Product: autoinducer-2 (AI-2) modifying protein LsrG

Products: NA

Alternate protein names: AI-2-degrading protein lsrG [H]

Number of amino acids: Translated: 104; Mature: 104

Protein sequence:

>104_residues
MFAMLVEINIKEGKEQEFLEVFARNHIGTRQEPGNLRFDVLRDPEIKTRFYAYEVYVNEQALEAHRQTAHYHRCVAELEP
LMTGARSKKLFDWVMPENLTNECG

Sequences:

>Translated_104_residues
MFAMLVEINIKEGKEQEFLEVFARNHIGTRQEPGNLRFDVLRDPEIKTRFYAYEVYVNEQALEAHRQTAHYHRCVAELEP
LMTGARSKKLFDWVMPENLTNECG
>Mature_104_residues
MFAMLVEINIKEGKEQEFLEVFARNHIGTRQEPGNLRFDVLRDPEIKTRFYAYEVYVNEQALEAHRQTAHYHRCVAELEP
LMTGARSKKLFDWVMPENLTNECG

Specific function: Involved in the degradation of phospho-AI-2, thereby terminating induction of the lsr operon and closing the AI-2 signaling cycle. Catalyzes the cleavage of phosphorylated 4,5- dihydroxy-2,3-pentanedione (P-DPD) to 2-phosphoglycolic acid (PG) and another

COG id: COG1359

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lsrG family [H]

Homologues:

Organism=Escherichia coli, GI1787797, Length=96, Percent_Identity=58.3333333333333, Blast_Score=122, Evalue=4e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007138
- InterPro:   IPR011008 [H]

Pfam domain/function: PF03992 ABM [H]

EC number: NA

Molecular weight: Translated: 12260; Mature: 12260

Theoretical pI: Translated: 5.62; Mature: 5.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFAMLVEINIKEGKEQEFLEVFARNHIGTRQEPGNLRFDVLRDPEIKTRFYAYEVYVNEQ
CEEEEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCEEEEEEEEEECHH
ALEAHRQTAHYHRCVAELEPLMTGARSKKLFDWVMPENLTNECG
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MFAMLVEINIKEGKEQEFLEVFARNHIGTRQEPGNLRFDVLRDPEIKTRFYAYEVYVNEQ
CEEEEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCEEEEEEEEEECHH
ALEAHRQTAHYHRCVAELEPLMTGARSKKLFDWVMPENLTNECG
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA