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The map label for this gene is apaH

Identifier: 15603075

GI number: 15603075

Start: 1402127

End: 1402954

Strand: Direct

Name: apaH

Synonym: PM1210

Alternate gene names: 15603075

Gene position: 1402127-1402954 (Clockwise)

Preceding gene: 15603074

Following gene: 15603076

Centisome position: 62.11

GC content: 41.43

Gene sequence:

>828_bases
ATGGCAACATATTTAGTAGGCGATTTACAGGGTTGTTACGATGAATTGCAACGTTTACTGGAAAAAGTGCAGTTCGATTC
AACACAAGATCAACTTTATTTGGTTGGGGATTTAGTGGCACGCGGGGATAAATCTCTCGAATGCTTGCGCTTTGTCAAAT
CTCTGGGTAAATCTGCCAAAACGGTGTTAGGCAACCATGATTTACACTTGATTTCCACTGCACTGGGTATTAAAAAAGTG
AAAGTGAGAGATCGAGTGGATGCCATTTTTCATGCTCCTGATTTTGAAGAATTAATTGATTGGCTACGTCATCAACCTTT
ACTTGTACACAATGAGCAACAGAACTTTTTAATGACCCATGCCGGCATTTCGCCGGATTGGGATCTTGCCACGGCGAAAC
AATGTGCGCATGAAGTGGAAAACGTGCTACGTCATGGTGATTACCACAATTTAATTGAAAATATGTATGAAAATCGCCCT
GATCGTTGGCATGATGATTTACAAGGTTTAGATCGTTTACGGTACAGCATTAATGTCTTTACCCGTATGCGTTTTTGCTA
TTGGGATCACCGCTTAGATTTCGACTGTAAGCTGCCACCAGAATCCGCCCCAGAAGAGCTCACGCCTTGGTTTAATTTAG
CCAACCCACTTTATCAAACAATCCCCATTGTGTTTGGACATTGGGCAAGTCTAGTCAATACGACAACACCGAATAATATC
TATGCGTTGGATACAGGTTGTGTATGGGGTAATCGCATGACTATGCTACGTTGGGAAGACAAACAATACTTTAGCCAACA
TGCGGTAAAAAATTATCGCGATTTTTAA

Upstream 100 bases:

>100_bases
ACGCTTAGCTAACTGGTTAACAGACAATCCACCAGCCGATGTTAACAAAGACGAAATGATTGAACATCTAGACGATTAAT
GGCATAAGTGCGGTGTAAAA

Downstream 100 bases:

>100_bases
TTAATCTGTTTATTTCCTATTCGTTTTCAGGTAACCTGTGCCACGTTTATTCATTGTTAAAACTGAATAAGCAAGATGCA
TATAACATGTTATGTTTATC

Product: diadenosine tetraphosphatase

Products: NA

Alternate protein names: Ap4A hydrolase; Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolase; Diadenosine tetraphosphatase

Number of amino acids: Translated: 275; Mature: 274

Protein sequence:

>275_residues
MATYLVGDLQGCYDELQRLLEKVQFDSTQDQLYLVGDLVARGDKSLECLRFVKSLGKSAKTVLGNHDLHLISTALGIKKV
KVRDRVDAIFHAPDFEELIDWLRHQPLLVHNEQQNFLMTHAGISPDWDLATAKQCAHEVENVLRHGDYHNLIENMYENRP
DRWHDDLQGLDRLRYSINVFTRMRFCYWDHRLDFDCKLPPESAPEELTPWFNLANPLYQTIPIVFGHWASLVNTTTPNNI
YALDTGCVWGNRMTMLRWEDKQYFSQHAVKNYRDF

Sequences:

>Translated_275_residues
MATYLVGDLQGCYDELQRLLEKVQFDSTQDQLYLVGDLVARGDKSLECLRFVKSLGKSAKTVLGNHDLHLISTALGIKKV
KVRDRVDAIFHAPDFEELIDWLRHQPLLVHNEQQNFLMTHAGISPDWDLATAKQCAHEVENVLRHGDYHNLIENMYENRP
DRWHDDLQGLDRLRYSINVFTRMRFCYWDHRLDFDCKLPPESAPEELTPWFNLANPLYQTIPIVFGHWASLVNTTTPNNI
YALDTGCVWGNRMTMLRWEDKQYFSQHAVKNYRDF
>Mature_274_residues
ATYLVGDLQGCYDELQRLLEKVQFDSTQDQLYLVGDLVARGDKSLECLRFVKSLGKSAKTVLGNHDLHLISTALGIKKVK
VRDRVDAIFHAPDFEELIDWLRHQPLLVHNEQQNFLMTHAGISPDWDLATAKQCAHEVENVLRHGDYHNLIENMYENRPD
RWHDDLQGLDRLRYSINVFTRMRFCYWDHRLDFDCKLPPESAPEELTPWFNLANPLYQTIPIVFGHWASLVNTTTPNNIY
ALDTGCVWGNRMTMLRWEDKQYFSQHAVKNYRDF

Specific function: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP

COG id: COG0639

COG function: function code T; Diadenosine tetraphosphatase and related serine/threonine protein phosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Ap4A hydrolase family

Homologues:

Organism=Escherichia coli, GI1786234, Length=266, Percent_Identity=54.5112781954887, Blast_Score=310, Evalue=6e-86,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): APAH_PASMU (P57922)

Other databases:

- EMBL:   AE004439
- RefSeq:   NP_246147.1
- ProteinModelPortal:   P57922
- SMR:   P57922
- GeneID:   1244557
- GenomeReviews:   AE004439_GR
- KEGG:   pmu:PM1210
- NMPDR:   fig|272843.1.peg.1210
- HOGENOM:   HBG724457
- OMA:   LVFGHWA
- ProtClustDB:   PRK00166
- BioCyc:   PMUL272843:PM1210-MONOMER
- BRENDA:   3.6.1.41
- HAMAP:   MF_00199
- InterPro:   IPR004617
- InterPro:   IPR004843
- PIRSF:   PIRSF000903
- TIGRFAMs:   TIGR00668

Pfam domain/function: PF00149 Metallophos

EC number: =3.6.1.41

Molecular weight: Translated: 32225; Mature: 32094

Theoretical pI: Translated: 6.18; Mature: 6.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATYLVGDLQGCYDELQRLLEKVQFDSTQDQLYLVGDLVARGDKSLECLRFVKSLGKSAK
CCCEEEHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHCCCCHHHHHHHHHHHCCHHH
TVLGNHDLHLISTALGIKKVKVRDRVDAIFHAPDFEELIDWLRHQPLLVHNEQQNFLMTH
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCEEEECCCCCEEEEE
AGISPDWDLATAKQCAHEVENVLRHGDYHNLIENMYENRPDRWHDDLQGLDRLRYSINVF
CCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
TRMRFCYWDHRLDFDCKLPPESAPEELTPWFNLANPLYQTIPIVFGHWASLVNTTTPNNI
HHHHHHHHHCCCCCCCCCCCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCE
YALDTGCVWGNRMTMLRWEDKQYFSQHAVKNYRDF
EEEECCEEECCCEEEEEECHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ATYLVGDLQGCYDELQRLLEKVQFDSTQDQLYLVGDLVARGDKSLECLRFVKSLGKSAK
CCEEEHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHCCCCHHHHHHHHHHHCCHHH
TVLGNHDLHLISTALGIKKVKVRDRVDAIFHAPDFEELIDWLRHQPLLVHNEQQNFLMTH
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCEEEECCCCCEEEEE
AGISPDWDLATAKQCAHEVENVLRHGDYHNLIENMYENRPDRWHDDLQGLDRLRYSINVF
CCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
TRMRFCYWDHRLDFDCKLPPESAPEELTPWFNLANPLYQTIPIVFGHWASLVNTTTPNNI
HHHHHHHHHCCCCCCCCCCCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCE
YALDTGCVWGNRMTMLRWEDKQYFSQHAVKNYRDF
EEEECCEEECCCEEEEEECHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11248100