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The map label for this gene is menG

Identifier: 15603033

GI number: 15603033

Start: 1364187

End: 1364687

Strand: Reverse

Name: menG

Synonym: PM1168

Alternate gene names: 15603033

Gene position: 1364687-1364187 (Counterclockwise)

Preceding gene: 15603034

Following gene: 15603032

Centisome position: 60.45

GC content: 39.52

Gene sequence:

>501_bases
ATGTACATTGATACTTCTGAGCTTTGTGATATTTATCTTGATCAAGTGGATGTAGTTGAACCTATTTTTTCAAGTTTTGG
TGGCGTAAATCGTTTTTATGGCAAAGTCACTACCGTAAAATGCTTTGAAAATAATGGCTTAATTACAGATATTTTAGAAG
AGAACGGCGAAGGTCGTGTTTTATTGATTGATGGTGGTGGTGCAGTACGTCGTGCTTTAGTCGATGCAGAGCTCGCACAA
TTAGCAGTCGATAATGGTTGGGAAGGCATTATTGTTTATGGTGCGGTTCGTCAAATTCAACAACTCGAAGAGATGGACAT
TGGTATACACGCCTTAGCCCCTATTCCTGTGGGCGCAGATAAACAGAACATCGGTGAAATTGATGTACCAGTCAATTTTG
GTGGTGTGACATTTTTCCCTGAAGATTATGTGTACGCCGATTTAACAGGTATTATTTTATCGCAAGAGCCTTTAGAGCTA
GATGAGTTTAATGACGCGTAA

Upstream 100 bases:

>100_bases
TGGCGTTACTTATCAATCTGTTATTTAGTTTAGGCTTGCTTATCAGCTAGCAATAGGCATATACTAACGAAATGAATTTT
CTTCAAAATAAGGTAATGTT

Downstream 100 bases:

>100_bases
TTTGCGCTGATATGACATTGCATAAAAGTGCAGCTGAAAAAGTCAAATTTTCGCTGCACTTTTTTGTTGCGCGATTGTTT
TTATGCGCTTGTTCACAAAT

Product: ribonuclease activity regulator protein RraA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 166; Mature: 166

Protein sequence:

>166_residues
MYIDTSELCDIYLDQVDVVEPIFSSFGGVNRFYGKVTTVKCFENNGLITDILEENGEGRVLLIDGGGAVRRALVDAELAQ
LAVDNGWEGIIVYGAVRQIQQLEEMDIGIHALAPIPVGADKQNIGEIDVPVNFGGVTFFPEDYVYADLTGIILSQEPLEL
DEFNDA

Sequences:

>Translated_166_residues
MYIDTSELCDIYLDQVDVVEPIFSSFGGVNRFYGKVTTVKCFENNGLITDILEENGEGRVLLIDGGGAVRRALVDAELAQ
LAVDNGWEGIIVYGAVRQIQQLEEMDIGIHALAPIPVGADKQNIGEIDVPVNFGGVTFFPEDYVYADLTGIILSQEPLEL
DEFNDA
>Mature_166_residues
MYIDTSELCDIYLDQVDVVEPIFSSFGGVNRFYGKVTTVKCFENNGLITDILEENGEGRVLLIDGGGAVRRALVDAELAQ
LAVDNGWEGIIVYGAVRQIQQLEEMDIGIHALAPIPVGADKQNIGEIDVPVNFGGVTFFPEDYVYADLTGIILSQEPLEL
DEFNDA

Specific function: Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities

COG id: COG0684

COG function: function code H; Demethylmenaquinone methyltransferase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RraA family

Homologues:

Organism=Escherichia coli, GI1790364, Length=161, Percent_Identity=67.0807453416149, Blast_Score=224, Evalue=2e-60,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RRAA_PASMU (Q9CLP9)

Other databases:

- EMBL:   AE004439
- RefSeq:   NP_246105.1
- ProteinModelPortal:   Q9CLP9
- SMR:   Q9CLP9
- PRIDE:   Q9CLP9
- GeneID:   1244515
- GenomeReviews:   AE004439_GR
- KEGG:   pmu:PM1168
- NMPDR:   fig|272843.1.peg.1168
- HOGENOM:   HBG668175
- OMA:   QNEWEGI
- ProtClustDB:   PRK09372
- BioCyc:   PMUL272843:PM1168-MONOMER
- HAMAP:   MF_00471
- InterPro:   IPR005493
- InterPro:   IPR014339
- InterPro:   IPR010203
- Gene3D:   G3DSA:3.50.30.40
- TIGRFAMs:   TIGR01935
- TIGRFAMs:   TIGR02998

Pfam domain/function: PF03737 Methyltransf_6; SSF89562 RNaseE_inh/diMeMenaQ_MeTrfase

EC number: NA

Molecular weight: Translated: 18145; Mature: 18145

Theoretical pI: Translated: 3.66; Mature: 3.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYIDTSELCDIYLDQVDVVEPIFSSFGGVNRFYGKVTTVKCFENNGLITDILEENGEGRV
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCEEEEEEECCCCEEEEHHHCCCCCEE
LLIDGGGAVRRALVDAELAQLAVDNGWEGIIVYGAVRQIQQLEEMDIGIHALAPIPVGAD
EEEECCHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHCCCEEEECCCCCCCC
KQNIGEIDVPVNFGGVTFFPEDYVYADLTGIILSQEPLELDEFNDA
CCCCCEEEEEEECCCEEECCCCCEEEEEEEEEECCCCCCCCCCCCC
>Mature Secondary Structure
MYIDTSELCDIYLDQVDVVEPIFSSFGGVNRFYGKVTTVKCFENNGLITDILEENGEGRV
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCEEEEEEECCCCEEEEHHHCCCCCEE
LLIDGGGAVRRALVDAELAQLAVDNGWEGIIVYGAVRQIQQLEEMDIGIHALAPIPVGAD
EEEECCHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHCCCEEEECCCCCCCC
KQNIGEIDVPVNFGGVTFFPEDYVYADLTGIILSQEPLELDEFNDA
CCCCCEEEEEEECCCEEECCCCCEEEEEEEEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11248100