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The map label for this gene is modD

Identifier: 15602976

GI number: 15602976

Start: 1305918

End: 1306766

Strand: Direct

Name: modD

Synonym: PM1111

Alternate gene names: 15602976

Gene position: 1305918-1306766 (Clockwise)

Preceding gene: 15602975

Following gene: 15602981

Centisome position: 57.85

GC content: 40.87

Gene sequence:

>849_bases
ATGCTTTATTTTTCAGACAACGAACTCGATGACTTTTTATTAGAAGATATCTATCGTGGTGATCTCACCACCCATGCATT
AGGATTAGAAAGTATCCCCGCTGAGATTTGCTTTAAACGTAAAAATGCCGGCATCGTCGCGGGTATCAGTATTGCGGAAA
AACTGCTCCGAAAACTCGACATTCACCCACAAGTGTATGTGAAAGAAGGAGAATTTGTCGAAGCAGGAAGCTTATTATTA
AGCGCCAAAGGCAGTGCTGATAAGCTACATCAAGCGTGGAAAGTGGTTCAATTGGTCTTGGAATGGTCATGTGGGGTTGC
ACAATATACCGCTGAAATGATTAGCAATGCGAAAGCCATTAATCCTGCTGCTGTTGTTGCTTGTACACGTAAAAGTATTC
CTAATACGCGCAAATTAGCCACAAATGCAGTCTTAGCCGCAGGTGGACATATTCACCGTCAAGGCTTGAGCGAAACCCTC
TTGGTATTTACCAATCATCGTAATCTCCTCTCTGATCCAGAAGATTGGCAAGGCATCGTGACAAGACTAAAGCAACAAGC
ACCAGAAAATAAAATTACACTGGAAGCTGATAACTTAGTGCAATTTGAACAAATGTTGACAGCCGATCCTGATATTATTC
AATTAGATAAATTCACGCTGGAACAAGTCAAACAAGCCTTGCATTTATTAGCGTTAGCCAATAAAAACATTACCTTATCT
GTGGCAGGTGGTGTTAACAAGCATAATGTGGCAGAGTATGCGAAACTCGGGATCCAACTTTTCATTACATCAGCACCTTA
TTATGCAGCGCCAGAAGATATTAAAGTGATTATCGAAAAACAGGTATAA

Upstream 100 bases:

>100_bases
CGTTATTAGTCACACACGATCCCAAAGAGGCCGATTACCTTTCTCACCGGCAAATTCGATTACACCAAGGACAACTTATT
TAATTGATAAGGACTGCACT

Downstream 100 bases:

>100_bases
ATAAGACAGTAAAAAATTGCGCCTAAGGGACACTTAGGCGCAATCATACTGTTTATCAACGAATAGGTACGCAACCGCCT
CGTTTAAATCTTAACTTACT

Product: molybdenum transport protein ModD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 282; Mature: 282

Protein sequence:

>282_residues
MLYFSDNELDDFLLEDIYRGDLTTHALGLESIPAEICFKRKNAGIVAGISIAEKLLRKLDIHPQVYVKEGEFVEAGSLLL
SAKGSADKLHQAWKVVQLVLEWSCGVAQYTAEMISNAKAINPAAVVACTRKSIPNTRKLATNAVLAAGGHIHRQGLSETL
LVFTNHRNLLSDPEDWQGIVTRLKQQAPENKITLEADNLVQFEQMLTADPDIIQLDKFTLEQVKQALHLLALANKNITLS
VAGGVNKHNVAEYAKLGIQLFITSAPYYAAPEDIKVIIEKQV

Sequences:

>Translated_282_residues
MLYFSDNELDDFLLEDIYRGDLTTHALGLESIPAEICFKRKNAGIVAGISIAEKLLRKLDIHPQVYVKEGEFVEAGSLLL
SAKGSADKLHQAWKVVQLVLEWSCGVAQYTAEMISNAKAINPAAVVACTRKSIPNTRKLATNAVLAAGGHIHRQGLSETL
LVFTNHRNLLSDPEDWQGIVTRLKQQAPENKITLEADNLVQFEQMLTADPDIIQLDKFTLEQVKQALHLLALANKNITLS
VAGGVNKHNVAEYAKLGIQLFITSAPYYAAPEDIKVIIEKQV
>Mature_282_residues
MLYFSDNELDDFLLEDIYRGDLTTHALGLESIPAEICFKRKNAGIVAGISIAEKLLRKLDIHPQVYVKEGEFVEAGSLLL
SAKGSADKLHQAWKVVQLVLEWSCGVAQYTAEMISNAKAINPAAVVACTRKSIPNTRKLATNAVLAAGGHIHRQGLSETL
LVFTNHRNLLSDPEDWQGIVTRLKQQAPENKITLEADNLVQFEQMLTADPDIIQLDKFTLEQVKQALHLLALANKNITLS
VAGGVNKHNVAEYAKLGIQLFITSAPYYAAPEDIKVIIEKQV

Specific function: NAD biosynthesis; aspartate to NaMN; third (last) step. [C]

COG id: COG0157

COG function: function code H; Nicotinate-nucleotide pyrophosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nadC/modD family

Homologues:

Organism=Escherichia coli, GI1786299, Length=248, Percent_Identity=26.2096774193548, Blast_Score=61, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6321162, Length=279, Percent_Identity=24.7311827956989, Blast_Score=79, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MODD_PASMU (Q9CLU4)

Other databases:

- EMBL:   AE004439
- RefSeq:   NP_246048.1
- ProteinModelPortal:   Q9CLU4
- SMR:   Q9CLU4
- GeneID:   1244458
- GenomeReviews:   AE004439_GR
- KEGG:   pmu:PM1111
- NMPDR:   fig|272843.1.peg.1111
- HOGENOM:   HBG751540
- OMA:   VACTRKN
- ProtClustDB:   PRK06096
- BioCyc:   PMUL272843:PM1111-MONOMER
- InterPro:   IPR013785
- InterPro:   IPR006242
- InterPro:   IPR002638
- InterPro:   IPR022412
- Gene3D:   G3DSA:3.20.20.70
- TIGRFAMs:   TIGR01334

Pfam domain/function: PF01729 QRPTase_C; PF02749 QRPTase_N; SSF51690 Q_phspho_trans

EC number: 2.4.2.-

Molecular weight: Translated: 31078; Mature: 31078

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLYFSDNELDDFLLEDIYRGDLTTHALGLESIPAEICFKRKNAGIVAGISIAEKLLRKLD
CEEECCCCHHHHHHHHHHHCCCHHHHHCHHHCCHHHHHHCCCCCEEEHHHHHHHHHHHHC
IHPQVYVKEGEFVEAGSLLLSAKGSADKLHQAWKVVQLVLEWSCGVAQYTAEMISNAKAI
CCCEEEEECCCEEECCCEEEECCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCC
NPAAVVACTRKSIPNTRKLATNAVLAAGGHIHRQGLSETLLVFTNHRNLLSDPEDWQGIV
CCHHHEEEHHHCCCCHHHHHHHHHHHCCCCHHHCCCCCEEEEEECCCCCCCCCHHHHHHH
TRLKQQAPENKITLEADNLVQFEQMLTADPDIIQLDKFTLEQVKQALHLLALANKNITLS
HHHHHHCCCCCEEEEHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHCCCCEEEE
VAGGVNKHNVAEYAKLGIQLFITSAPYYAAPEDIKVIIEKQV
EECCCCCHHHHHHHHCCEEEEEECCCCCCCCCHHEEEEECCC
>Mature Secondary Structure
MLYFSDNELDDFLLEDIYRGDLTTHALGLESIPAEICFKRKNAGIVAGISIAEKLLRKLD
CEEECCCCHHHHHHHHHHHCCCHHHHHCHHHCCHHHHHHCCCCCEEEHHHHHHHHHHHHC
IHPQVYVKEGEFVEAGSLLLSAKGSADKLHQAWKVVQLVLEWSCGVAQYTAEMISNAKAI
CCCEEEEECCCEEECCCEEEECCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCC
NPAAVVACTRKSIPNTRKLATNAVLAAGGHIHRQGLSETLLVFTNHRNLLSDPEDWQGIV
CCHHHEEEHHHCCCCHHHHHHHHHHHCCCCHHHCCCCCEEEEEECCCCCCCCCHHHHHHH
TRLKQQAPENKITLEADNLVQFEQMLTADPDIIQLDKFTLEQVKQALHLLALANKNITLS
HHHHHHCCCCCEEEEHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHCCCCEEEE
VAGGVNKHNVAEYAKLGIQLFITSAPYYAAPEDIKVIIEKQV
EECCCCCHHHHHHHHCCEEEEEECCCCCCCCCHHEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11248100