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The map label for this gene is yhxB [C]

Identifier: 15602939

GI number: 15602939

Start: 1265437

End: 1267092

Strand: Direct

Name: yhxB [C]

Synonym: PM1074

Alternate gene names: 15602939

Gene position: 1265437-1267092 (Clockwise)

Preceding gene: 15602938

Following gene: 15602942

Centisome position: 56.06

GC content: 43.54

Gene sequence:

>1656_bases
ATGTCAATCTTTACCCTTGCTCAACATTGGTTAGCACAAGATCCTGATCCTGAAACACATGCAGAACTTACCGCACTTCT
TGACGCGGCAAAAACGGGGGATGCGAAAGCAAGCACAGAATTAAATGCACGCTTTGATGGTCGTTTACAGTTTGGTACTG
CAGGCTTGCGTGGTCGTTTACAAGCCGGACCAATGGGGATGAACCGCGTGTTAGTTGCACAAGCAGCGGGGGGCTTAGCC
GATTATTTAAAAGACTATGATAAAACCCCTTCCATTGTCATTGGCTATGACGGGCGTAAAAATTCAGATGTATTTGCACG
CGATACTGCCGAAATTATGGCAGGCGCAGGCATCAAAGCCTACTTATTACCACGTAAATTGCCAACCCCAGTCCTTGCTT
ATGCGATCAAATATTTTGATACCACAGCGGGGGTCATGGTGACCGCAAGTCATAACCCACCAGAAGATAATGGCTATAAA
GTCTATTTAGGTAAAGCCAATGGTGGCGGTCAAATTGTTTCTCCAGCAGACCAAGACATCGCTAAACTGATTGATAAAGT
GGCGGCTGGCTCCATTAAAGATTTACCACGTAGCCAAGATTTTATCGTACTGGATGACGAAGTCGTTGATGCCTACATTG
CGAAAACAGCTAGCCTTGCCAAAGAACCCCAAACAGACATTAATTATGTCTATACCGCAATGCACGGTGTCGGCTATGAA
GTATTGAGCAAAACGTTAGCTAAAGCAGGTTTACCACAACCACATTTAGTGGCGGAGCAAGTGTGGCCAGATGGCACGTT
CCCAACAGTAAACTTCCCGAATCCAGAAGAAAAAGGCGCATTAGACTTAGCCATTAAAGTGGCGAAAGAGAAAAATGCCG
AATTTATCATTGCGAATGACCCAGATGCTGACCGCTTAGCCGTCGCGGTACCAGATGCAGAAGGCAACTGGAAACCGTTG
CATGGTAATGTGGTCGGTTGTTTCTTAGGTTGGTACTTAGCGAAACAATATCATGCACAAGGACAAAAAGGCATTCTTGC
TTGTTCATTAGTTTCTTCGCCAGCACTGGCTGAGATTGCGAAAAAATACGGTTTCCAATCAGAAGAAACACTCACTGGCT
TTAAATATATTGGTAAAGTCGATGGGTTATTATTCGGCTTTGAGGAAGCATTAGGTTATTTAGTTGACCCAGACAAAGTC
CGTGATAAAGACGGTATTTCTGCCGCTATTTCGTTTTTAGATTTAGTACGTTACTTGAAAAAACAAGGCAAAACACTCGC
CGACTATGCCGATGAATTCACTCAAGAATTTGGTGCTTATGTAAGTGGACAAATCTCGATTCGTGTTGATGACTTATCTG
AAATTGGCAAATTAATGAGTGCACTGCGTCAAAATCCACCAAGCGATATCGGCGGTTTCAAAGTCGCACAATTCTTGGAT
CACACCAAAACCGATCGCCAAAGTGATATTTTAGTTTTCGTTCTTGAAAATGGTAGTCGTTTGATCGTACGCCCATCTGG
TACAGAACCAAAAATCAAGTTCTACCTCGATGCGAAAGGGAAAGATCCAAAAGATGCTGAGCAAGTGTTAGCCCAATTTG
ATGAAAGTGTTCGTCACATTTTACGTCAAGATGAATTTGGTAAGCAGGATTGCTAA

Upstream 100 bases:

>100_bases
GTTCAAATAATTTGAGTTTGATCATTTTCATTCTGCTTTTTTTCGGCTAGTCTAACTATGTTATATACCGCATAATTTTT
AATAAAATTAAGGAGAATTT

Downstream 100 bases:

>100_bases
TCTGACTTAAGCTACAACATGGCACAGTACACTGTGCCATTTTTCTTTACGCAGCTTAAGATAAACAGCGATTCAACGTC
CCTTCACATTTAATATTTTT

Product: YhxB

Products: NA

Alternate protein names: PMM [H]

Number of amino acids: Translated: 551; Mature: 550

Protein sequence:

>551_residues
MSIFTLAQHWLAQDPDPETHAELTALLDAAKTGDAKASTELNARFDGRLQFGTAGLRGRLQAGPMGMNRVLVAQAAGGLA
DYLKDYDKTPSIVIGYDGRKNSDVFARDTAEIMAGAGIKAYLLPRKLPTPVLAYAIKYFDTTAGVMVTASHNPPEDNGYK
VYLGKANGGGQIVSPADQDIAKLIDKVAAGSIKDLPRSQDFIVLDDEVVDAYIAKTASLAKEPQTDINYVYTAMHGVGYE
VLSKTLAKAGLPQPHLVAEQVWPDGTFPTVNFPNPEEKGALDLAIKVAKEKNAEFIIANDPDADRLAVAVPDAEGNWKPL
HGNVVGCFLGWYLAKQYHAQGQKGILACSLVSSPALAEIAKKYGFQSEETLTGFKYIGKVDGLLFGFEEALGYLVDPDKV
RDKDGISAAISFLDLVRYLKKQGKTLADYADEFTQEFGAYVSGQISIRVDDLSEIGKLMSALRQNPPSDIGGFKVAQFLD
HTKTDRQSDILVFVLENGSRLIVRPSGTEPKIKFYLDAKGKDPKDAEQVLAQFDESVRHILRQDEFGKQDC

Sequences:

>Translated_551_residues
MSIFTLAQHWLAQDPDPETHAELTALLDAAKTGDAKASTELNARFDGRLQFGTAGLRGRLQAGPMGMNRVLVAQAAGGLA
DYLKDYDKTPSIVIGYDGRKNSDVFARDTAEIMAGAGIKAYLLPRKLPTPVLAYAIKYFDTTAGVMVTASHNPPEDNGYK
VYLGKANGGGQIVSPADQDIAKLIDKVAAGSIKDLPRSQDFIVLDDEVVDAYIAKTASLAKEPQTDINYVYTAMHGVGYE
VLSKTLAKAGLPQPHLVAEQVWPDGTFPTVNFPNPEEKGALDLAIKVAKEKNAEFIIANDPDADRLAVAVPDAEGNWKPL
HGNVVGCFLGWYLAKQYHAQGQKGILACSLVSSPALAEIAKKYGFQSEETLTGFKYIGKVDGLLFGFEEALGYLVDPDKV
RDKDGISAAISFLDLVRYLKKQGKTLADYADEFTQEFGAYVSGQISIRVDDLSEIGKLMSALRQNPPSDIGGFKVAQFLD
HTKTDRQSDILVFVLENGSRLIVRPSGTEPKIKFYLDAKGKDPKDAEQVLAQFDESVRHILRQDEFGKQDC
>Mature_550_residues
SIFTLAQHWLAQDPDPETHAELTALLDAAKTGDAKASTELNARFDGRLQFGTAGLRGRLQAGPMGMNRVLVAQAAGGLAD
YLKDYDKTPSIVIGYDGRKNSDVFARDTAEIMAGAGIKAYLLPRKLPTPVLAYAIKYFDTTAGVMVTASHNPPEDNGYKV
YLGKANGGGQIVSPADQDIAKLIDKVAAGSIKDLPRSQDFIVLDDEVVDAYIAKTASLAKEPQTDINYVYTAMHGVGYEV
LSKTLAKAGLPQPHLVAEQVWPDGTFPTVNFPNPEEKGALDLAIKVAKEKNAEFIIANDPDADRLAVAVPDAEGNWKPLH
GNVVGCFLGWYLAKQYHAQGQKGILACSLVSSPALAEIAKKYGFQSEETLTGFKYIGKVDGLLFGFEEALGYLVDPDKVR
DKDGISAAISFLDLVRYLKKQGKTLADYADEFTQEFGAYVSGQISIRVDDLSEIGKLMSALRQNPPSDIGGFKVAQFLDH
TKTDRQSDILVFVLENGSRLIVRPSGTEPKIKFYLDAKGKDPKDAEQVLAQFDESVRHILRQDEFGKQDC

Specific function: This Enzyme Participates In Both The Breakdown And Synthesis Of Glucose. [C]

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family [H]

Homologues:

Organism=Homo sapiens, GI63055049, Length=590, Percent_Identity=33.728813559322, Blast_Score=285, Evalue=1e-76,
Organism=Homo sapiens, GI31377548, Length=563, Percent_Identity=33.7477797513321, Blast_Score=270, Evalue=3e-72,
Organism=Escherichia coli, GI1786904, Length=505, Percent_Identity=24.950495049505, Blast_Score=77, Evalue=4e-15,
Organism=Escherichia coli, GI1789566, Length=503, Percent_Identity=25.844930417495, Blast_Score=70, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI71993870, Length=588, Percent_Identity=34.1836734693878, Blast_Score=289, Evalue=3e-78,
Organism=Caenorhabditis elegans, GI71993878, Length=314, Percent_Identity=36.624203821656, Blast_Score=182, Evalue=6e-46,
Organism=Saccharomyces cerevisiae, GI6323934, Length=612, Percent_Identity=35.9477124183007, Blast_Score=280, Evalue=3e-76,
Organism=Drosophila melanogaster, GI20129809, Length=594, Percent_Identity=35.016835016835, Blast_Score=289, Evalue=4e-78,
Organism=Drosophila melanogaster, GI24651977, Length=553, Percent_Identity=35.2622061482821, Blast_Score=265, Evalue=5e-71,
Organism=Drosophila melanogaster, GI24653722, Length=493, Percent_Identity=33.0628803245436, Blast_Score=229, Evalue=4e-60,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841 [H]

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV [H]

EC number: =5.4.2.8 [H]

Molecular weight: Translated: 59900; Mature: 59769

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: PS00710 PGM_PMM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIFTLAQHWLAQDPDPETHAELTALLDAAKTGDAKASTELNARFDGRLQFGTAGLRGRL
CCHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCEECCEEEECCCCCCCCC
QAGPMGMNRVLVAQAAGGLADYLKDYDKTPSIVIGYDGRKNSDVFARDTAEIMAGAGIKA
CCCCCCCCEEEEEHHCCCHHHHHHHHCCCCCEEEECCCCCCCCEEHHHHHHHHHCCCCEE
YLLPRKLPTPVLAYAIKYFDTTAGVMVTASHNPPEDNGYKVYLGKANGGGQIVSPADQDI
EECCCCCCCHHHHHHHHHHCCCCCEEEEECCCCCCCCCEEEEEEECCCCCCCCCCCHHHH
AKLIDKVAAGSIKDLPRSQDFIVLDDEVVDAYIAKTASLAKEPQTDINYVYTAMHGVGYE
HHHHHHHHCCCHHCCCCCCCEEEECHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCHH
VLSKTLAKAGLPQPHLVAEQVWPDGTFPTVNFPNPEEKGALDLAIKVAKEKNAEFIIAND
HHHHHHHHCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCEEEECC
PDADRLAVAVPDAEGNWKPLHGNVVGCFLGWYLAKQYHAQGQKGILACSLVSSPALAEIA
CCCCEEEEEECCCCCCCEECCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHH
KKYGFQSEETLTGFKYIGKVDGLLFGFEEALGYLVDPDKVRDKDGISAAISFLDLVRYLK
HHHCCCCCHHHHHHHHHHHHHHHHEEHHHHCCCCCCCHHHCCCCHHHHHHHHHHHHHHHH
KQGKTLADYADEFTQEFGAYVSGQISIRVDDLSEIGKLMSALRQNPPSDIGGFKVAQFLD
HCCCCHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
HTKTDRQSDILVFVLENGSRLIVRPSGTEPKIKFYLDAKGKDPKDAEQVLAQFDESVRHI
HHCCCCCCCEEEEEEECCCEEEEECCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHH
LRQDEFGKQDC
HHCCCCCCCCC
>Mature Secondary Structure 
SIFTLAQHWLAQDPDPETHAELTALLDAAKTGDAKASTELNARFDGRLQFGTAGLRGRL
CHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCEECCEEEECCCCCCCCC
QAGPMGMNRVLVAQAAGGLADYLKDYDKTPSIVIGYDGRKNSDVFARDTAEIMAGAGIKA
CCCCCCCCEEEEEHHCCCHHHHHHHHCCCCCEEEECCCCCCCCEEHHHHHHHHHCCCCEE
YLLPRKLPTPVLAYAIKYFDTTAGVMVTASHNPPEDNGYKVYLGKANGGGQIVSPADQDI
EECCCCCCCHHHHHHHHHHCCCCCEEEEECCCCCCCCCEEEEEEECCCCCCCCCCCHHHH
AKLIDKVAAGSIKDLPRSQDFIVLDDEVVDAYIAKTASLAKEPQTDINYVYTAMHGVGYE
HHHHHHHHCCCHHCCCCCCCEEEECHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCHH
VLSKTLAKAGLPQPHLVAEQVWPDGTFPTVNFPNPEEKGALDLAIKVAKEKNAEFIIAND
HHHHHHHHCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCEEEECC
PDADRLAVAVPDAEGNWKPLHGNVVGCFLGWYLAKQYHAQGQKGILACSLVSSPALAEIA
CCCCEEEEEECCCCCCCEECCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHH
KKYGFQSEETLTGFKYIGKVDGLLFGFEEALGYLVDPDKVRDKDGISAAISFLDLVRYLK
HHHCCCCCHHHHHHHHHHHHHHHHEEHHHHCCCCCCCHHHCCCCHHHHHHHHHHHHHHHH
KQGKTLADYADEFTQEFGAYVSGQISIRVDDLSEIGKLMSALRQNPPSDIGGFKVAQFLD
HCCCCHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
HTKTDRQSDILVFVLENGSRLIVRPSGTEPKIKFYLDAKGKDPKDAEQVLAQFDESVRHI
HHCCCCCCCEEEEEEECCCEEEEECCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHH
LRQDEFGKQDC
HHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800; 10675023 [H]