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The map label for this gene is lnt

Identifier: 15602897

GI number: 15602897

Start: 1213879

End: 1215441

Strand: Reverse

Name: lnt

Synonym: PM1032

Alternate gene names: 15602897

Gene position: 1215441-1213879 (Counterclockwise)

Preceding gene: 15602898

Following gene: 15602895

Centisome position: 53.84

GC content: 40.37

Gene sequence:

>1563_bases
GTGCTTCATTATTTAAAGAAGATGAAAAAAAAGATTTTTACTTATTTTATTGCGATTTTTTCAGGCATTATCGGGGTGTT
AGCCTTTTCCCCTTTTGATTATTGGGGTTGTGCTTACTTATCGCTTTTAGGTCTTATTTTTGTTGCTAAAACAGCGGAAA
AAAAGACCGCACTTTGGTCGGCATTTTTGTGGGGATTAGCTTTTTTCACTTTTGGGATAAATTGGGTACACGTTAGTATT
CATCAATTTGGTGGTGCCTCTGTCGTGGTGAGCTATGTGTTAGTCCTTGTCTTAGCCGCCTATCTTGCATTGTATCCGAT
GCTCTTTGCTTATTTGATCCAGCGTTTTCAAATCAGTAGCTTAGCGATGTTCCCCGTGATTTGGACCTTTACCGAATTTT
TACGCGGCTGGCTCTTTACCGGGTTTCCGTGGTTACAATTTGGTTATAGTCAAATCGATAGCCCATTTGCTCATCTCGCG
CCGATGTTTGGTGTTACTGGCGTCACTTTCTTTGTAATGTGGGTCAGTGCGGTGATTTTTAATTTACTTTCCGTCTTGCT
TATTAAACCAAGAAAGTGGAATGTTGTGATAGCTAATCTCCTTTTACTCACACTAGTTGGTGGATTGTCAGCTTATTCTT
CCAAGGCTGAGTATGTCAGAAAAATAGAAGACAGGGATTTGCTTGTGACGTTAGCACAGGGCAATATTGAGCAAAATTTA
AAATGGGAACCAGAATATCTGTATCAAACTTTAGATATCTATCATAAGTTAATTAGTCAGCATCTCGGTAAAACTGACGT
CATTATTTTGCCTGAATCTGCATTGCCAGTGTTAGAAAATCATATTCAGCCTTTTTTCCAAGGGCTACAAGCACATGCAC
AACAAGCTGGAACGGAAATCGTCATGGGGACTATCTATCAAGATAAAACAGCAAATAAGTTATTAAATTCAATTATTACC
TTGGGAAATACGGATTTCCCTTATTCATTAGAAACGACAAATCGTTACAGTAAGCATCACCTTGTGCCTTTTGGTGAATA
TGTTCCTTTAGAGACATTATTGCGTCCATTAGGGAGTGTGTTTAATTTACCCATGTCTGCTTTCCAAAGTGGTGATGAAA
TTCAATCGCCGTTAGTGGTCAAAAATCGCCAGCTAAGTGCGGCAATTTGTTATGAGATTATTTTGGGTGAGCAACTAAGG
AAGAATGTGAAACAAGACACGGATTTCATTCTCACAGTCTCAAATGATGCGTGGTTTGGTGACTCTATTGGACCTTGGCA
ACATTTACAGATGGCAAGAATGCGTGCTTTAGAGTTTGGGAAACCAGTCATTCGTGCCACTAATACTGGCATTAGCGTGT
TTATTGATGAGCAAGGTAAAATTGTTGCACAAGCGCCGCAATTCATTGAAACGACGTTAACGCATAAAGTGGCGGCTACG
GAAGGTCAAACGCCTTACGCTGTGTTTGGTAATACCGCTATCTATGGACTGTCGTTGCTACTGCTCTTAATGCGTGGGTT
CGGCGCACTGATTCGTCGTCGTTTATTCATGCCCCGTCTGTAA

Upstream 100 bases:

>100_bases
ATTACTGTCACGGATGAGCAGTTAGCTGAAATTGAAAAAGCCGAAGAACTAAAGGAAGATTAAACACGTCGATACGGAAG
ACGAGCACGAGTAAAGACTC

Downstream 100 bases:

>100_bases
GTCAGAACAAACAAAAAAGCACTGAAATATCAGTGCTTTTTTGTCAAAATAGGTTAGCGGCTACGGAAAATAATGCGACC
TTTGTTTAAGTCGTAAGGTG

Product: apolipoprotein N-acyltransferase

Products: NA

Alternate protein names: ALP N-acyltransferase

Number of amino acids: Translated: 520; Mature: 520

Protein sequence:

>520_residues
MLHYLKKMKKKIFTYFIAIFSGIIGVLAFSPFDYWGCAYLSLLGLIFVAKTAEKKTALWSAFLWGLAFFTFGINWVHVSI
HQFGGASVVVSYVLVLVLAAYLALYPMLFAYLIQRFQISSLAMFPVIWTFTEFLRGWLFTGFPWLQFGYSQIDSPFAHLA
PMFGVTGVTFFVMWVSAVIFNLLSVLLIKPRKWNVVIANLLLLTLVGGLSAYSSKAEYVRKIEDRDLLVTLAQGNIEQNL
KWEPEYLYQTLDIYHKLISQHLGKTDVIILPESALPVLENHIQPFFQGLQAHAQQAGTEIVMGTIYQDKTANKLLNSIIT
LGNTDFPYSLETTNRYSKHHLVPFGEYVPLETLLRPLGSVFNLPMSAFQSGDEIQSPLVVKNRQLSAAICYEIILGEQLR
KNVKQDTDFILTVSNDAWFGDSIGPWQHLQMARMRALEFGKPVIRATNTGISVFIDEQGKIVAQAPQFIETTLTHKVAAT
EGQTPYAVFGNTAIYGLSLLLLLMRGFGALIRRRLFMPRL

Sequences:

>Translated_520_residues
MLHYLKKMKKKIFTYFIAIFSGIIGVLAFSPFDYWGCAYLSLLGLIFVAKTAEKKTALWSAFLWGLAFFTFGINWVHVSI
HQFGGASVVVSYVLVLVLAAYLALYPMLFAYLIQRFQISSLAMFPVIWTFTEFLRGWLFTGFPWLQFGYSQIDSPFAHLA
PMFGVTGVTFFVMWVSAVIFNLLSVLLIKPRKWNVVIANLLLLTLVGGLSAYSSKAEYVRKIEDRDLLVTLAQGNIEQNL
KWEPEYLYQTLDIYHKLISQHLGKTDVIILPESALPVLENHIQPFFQGLQAHAQQAGTEIVMGTIYQDKTANKLLNSIIT
LGNTDFPYSLETTNRYSKHHLVPFGEYVPLETLLRPLGSVFNLPMSAFQSGDEIQSPLVVKNRQLSAAICYEIILGEQLR
KNVKQDTDFILTVSNDAWFGDSIGPWQHLQMARMRALEFGKPVIRATNTGISVFIDEQGKIVAQAPQFIETTLTHKVAAT
EGQTPYAVFGNTAIYGLSLLLLLMRGFGALIRRRLFMPRL
>Mature_520_residues
MLHYLKKMKKKIFTYFIAIFSGIIGVLAFSPFDYWGCAYLSLLGLIFVAKTAEKKTALWSAFLWGLAFFTFGINWVHVSI
HQFGGASVVVSYVLVLVLAAYLALYPMLFAYLIQRFQISSLAMFPVIWTFTEFLRGWLFTGFPWLQFGYSQIDSPFAHLA
PMFGVTGVTFFVMWVSAVIFNLLSVLLIKPRKWNVVIANLLLLTLVGGLSAYSSKAEYVRKIEDRDLLVTLAQGNIEQNL
KWEPEYLYQTLDIYHKLISQHLGKTDVIILPESALPVLENHIQPFFQGLQAHAQQAGTEIVMGTIYQDKTANKLLNSIIT
LGNTDFPYSLETTNRYSKHHLVPFGEYVPLETLLRPLGSVFNLPMSAFQSGDEIQSPLVVKNRQLSAAICYEIILGEQLR
KNVKQDTDFILTVSNDAWFGDSIGPWQHLQMARMRALEFGKPVIRATNTGISVFIDEQGKIVAQAPQFIETTLTHKVAAT
EGQTPYAVFGNTAIYGLSLLLLLMRGFGALIRRRLFMPRL

Specific function: Transfers the fatty acyl group on membrane lipoproteins

COG id: COG0815

COG function: function code M; Apolipoprotein N-acyltransferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 CN hydrolase domain

Homologues:

Organism=Escherichia coli, GI1786878, Length=514, Percent_Identity=44.9416342412451, Blast_Score=427, Evalue=1e-121,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LNT_PASMU (Q9CM14)

Other databases:

- EMBL:   AE004439
- RefSeq:   NP_245969.1
- ProteinModelPortal:   Q9CM14
- GeneID:   1244379
- GenomeReviews:   AE004439_GR
- KEGG:   pmu:PM1032
- NMPDR:   fig|272843.1.peg.1032
- HOGENOM:   HBG616234
- OMA:   LENHIQP
- ProtClustDB:   PRK00302
- BioCyc:   PMUL272843:PM1032-MONOMER
- HAMAP:   MF_01148
- InterPro:   IPR004563
- InterPro:   IPR003010
- Gene3D:   G3DSA:3.60.110.10
- TIGRFAMs:   TIGR00546

Pfam domain/function: PF00795 CN_hydrolase; SSF56317 Ntlse/CNhydtse

EC number: 2.3.1.- [C]

Molecular weight: Translated: 58734; Mature: 58734

Theoretical pI: Translated: 9.40; Mature: 9.40

Prosite motif: PS50263 CN_HYDROLASE

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xe14f14c)-; HASH(0xe195c30)-; HASH(0xd27cfc4)-; HASH(0xe0c96d4)-; HASH(0xdcf952c)-; HASH(0xc670870)-; HASH(0xd764468)-; HASH(0xd5f5460)-;

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
>Mature Secondary Structure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CCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferases; Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11248100