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The map label for this gene is htpG

Identifier: 15602889

GI number: 15602889

Start: 1206040

End: 1207935

Strand: Reverse

Name: htpG

Synonym: PM1024

Alternate gene names: 15602889

Gene position: 1207935-1206040 (Counterclockwise)

Preceding gene: 15602890

Following gene: 15602888

Centisome position: 53.51

GC content: 40.24

Gene sequence:

>1896_bases
ATGTCGACGAATCAAGAAACGCGTGGTTTTCAATCAGAAGTCAAACAACTTCTTCAACTAATGATCCATTCTCTCTATTC
CAATAAAGAAATTTTCTTACGTGAATTAATTTCCAATGCCTCTGATGCGGCAGATAAATTGCGTTTTAAAGCCTTGTCTG
TGCCAGAGCTTTATGAAGGTGATGGGGATTTAAAAGTGCGTATTCGTTTTGATGAAGAGAAAGGTACCTTAACCATTAGT
GATAATGGCATTGGGATGACGCGTGATGAAGTAATCGATCATTTAGGTACCATTGCCAAATCGGGTACCAAAGAATTTTT
AAGTGCATTAGGACAAGATCAAGCCAAAGATAGCCAATTAATTGGTCAGTTTGGGGTCGGTTTTTATTCCGCCTTTATTG
TGGCAGATAAAGTCACTGTGAAAACGCGTGCAGCAGGCGTAAGTGCAGATAAAGCGGTGCTTTGGGAATCGGCAGGCGAA
GGTGAGTATTCTGTGGCGGATATTGACAAAAAAGAACGCGGTACCGAAATTACCCTTCACTTACGTGAAGATGAAAAAGC
CTTTTTAAATGATTGGCGCTTACGTGAAATTATCGGCAAATATTCGGATCATATTGGTTTGCCAGTAGAAATTCTAGCCA
AAGAATATGACGATGAAGGCAAAGAAACCGGCATTAAATGGGAAAAAATCAATAAAGCGCAAGCCTTGTGGACACGTGCA
AAAAATGAGATTTCGGAGGAAGAATATCAAGAGTTCTATAAGCATTTAAGTCATGATTTTACCGATCCGTTACTTTGGGC
ACACAATAAAGTAGAAGGAAATCAAGAATATACCAGTTTACTTTATGTGCCAGCAAAAGCCCCTTGGGATTTATTTAATC
GCGAACATAAACACGGCTTAAAGCTGTATGTGCAACGTGTCTTTATTATGGATGATGCGCAAGTCTTTATGCCAAATTAT
CTGCGTTTTATGCGTGGTTTATTAGATTCCAATGATTTGCCACTGAATGTATCGCGCGAAATTTTACAAGATAACAAAGT
CACGAGTGCTTTACGTAAAGCCCTAACGAAACGTGCATTGCAAATGCTCGAAAAATTAGCCAAAGACGATGCAGAGAAAT
ACCAACGCTTTTGGCAAGAGTTTGGTTTGGTGTTAAAAGAAGGTCCAGCAGAAGATTTTGCAAATAAAGAAACGATTGCA
AAATTATTACGTTTTGCTTCAACACACAATGACAGCAGCCAACAAAGCGTGTCGTTAGAAGACTATGTGGCACGTATGAA
AGAAGGACAAAAGGCGATTTATTATATTACGGCAGATACTTATGTCGCCGCGAAAAACTCACCGCACTTAGAATTGTTCA
ATAAGAAAGGCATTGAAGTATTATTGTTGTCCGATCGTATTGATGAATGGATGTTAAGCTACTTAACGGAATTTGATGGT
AAGCCACTGCAAACCATCAGTAAAGCGGATTTAGATCTAGGTGATTTAGCGGATAAAGAGGAAGACAGTCAAAAAGCACA
AGATGAGCAATATGCTTCTTTTGTGGAACGTGTGAAAACCTTGCTTGGCGAGCGCGTGAAAGAAGTGCGCTTAACTCACC
GTTTAACGGATACGCCAGCGGTTGTTTCGACGGGTGATGACCAGATGACCACCCAAATGGCGAAATTGTTCGCTGCGGCG
GGTCAAGCGATGCCAGAGGTTAAATACACCTTCGAATTAAATCCAGAACATGGTTTAGTACAAAAAGTAGCAGAAATTGC
CGATGAGCAGCAATTTGCCGATTGGATTGAATTGCTACTTGAACAAGCAATGTTGGCTGAGCGTGGTAGCCTTGAAAATC
CAGTTGCCTTTATTAAACGCATGAACACCTTGTTAAGTAAACTCACAAGTCATTAA

Upstream 100 bases:

>100_bases
TTTGCGCTTAATAGTAGTATTTTCCCTTGAAATTTCGTTTTTTGCACTTATATCAGGAAGCACTTATTAAGTGTAATAAA
GCGTAACAGAAGGAAATATT

Downstream 100 bases:

>100_bases
CGTCGTATTTTGAAATATGCTAAAATCCCTTGGGTCAAATATCTAAGGGATTTTTATTTTAAGGAGAAATGATGATTACT
GTTTATGGCATTAAAAATTG

Product: heat shock protein 90

Products: NA

Alternate protein names: Heat shock protein htpG; High temperature protein G

Number of amino acids: Translated: 631; Mature: 630

Protein sequence:

>631_residues
MSTNQETRGFQSEVKQLLQLMIHSLYSNKEIFLRELISNASDAADKLRFKALSVPELYEGDGDLKVRIRFDEEKGTLTIS
DNGIGMTRDEVIDHLGTIAKSGTKEFLSALGQDQAKDSQLIGQFGVGFYSAFIVADKVTVKTRAAGVSADKAVLWESAGE
GEYSVADIDKKERGTEITLHLREDEKAFLNDWRLREIIGKYSDHIGLPVEILAKEYDDEGKETGIKWEKINKAQALWTRA
KNEISEEEYQEFYKHLSHDFTDPLLWAHNKVEGNQEYTSLLYVPAKAPWDLFNREHKHGLKLYVQRVFIMDDAQVFMPNY
LRFMRGLLDSNDLPLNVSREILQDNKVTSALRKALTKRALQMLEKLAKDDAEKYQRFWQEFGLVLKEGPAEDFANKETIA
KLLRFASTHNDSSQQSVSLEDYVARMKEGQKAIYYITADTYVAAKNSPHLELFNKKGIEVLLLSDRIDEWMLSYLTEFDG
KPLQTISKADLDLGDLADKEEDSQKAQDEQYASFVERVKTLLGERVKEVRLTHRLTDTPAVVSTGDDQMTTQMAKLFAAA
GQAMPEVKYTFELNPEHGLVQKVAEIADEQQFADWIELLLEQAMLAERGSLENPVAFIKRMNTLLSKLTSH

Sequences:

>Translated_631_residues
MSTNQETRGFQSEVKQLLQLMIHSLYSNKEIFLRELISNASDAADKLRFKALSVPELYEGDGDLKVRIRFDEEKGTLTIS
DNGIGMTRDEVIDHLGTIAKSGTKEFLSALGQDQAKDSQLIGQFGVGFYSAFIVADKVTVKTRAAGVSADKAVLWESAGE
GEYSVADIDKKERGTEITLHLREDEKAFLNDWRLREIIGKYSDHIGLPVEILAKEYDDEGKETGIKWEKINKAQALWTRA
KNEISEEEYQEFYKHLSHDFTDPLLWAHNKVEGNQEYTSLLYVPAKAPWDLFNREHKHGLKLYVQRVFIMDDAQVFMPNY
LRFMRGLLDSNDLPLNVSREILQDNKVTSALRKALTKRALQMLEKLAKDDAEKYQRFWQEFGLVLKEGPAEDFANKETIA
KLLRFASTHNDSSQQSVSLEDYVARMKEGQKAIYYITADTYVAAKNSPHLELFNKKGIEVLLLSDRIDEWMLSYLTEFDG
KPLQTISKADLDLGDLADKEEDSQKAQDEQYASFVERVKTLLGERVKEVRLTHRLTDTPAVVSTGDDQMTTQMAKLFAAA
GQAMPEVKYTFELNPEHGLVQKVAEIADEQQFADWIELLLEQAMLAERGSLENPVAFIKRMNTLLSKLTSH
>Mature_630_residues
STNQETRGFQSEVKQLLQLMIHSLYSNKEIFLRELISNASDAADKLRFKALSVPELYEGDGDLKVRIRFDEEKGTLTISD
NGIGMTRDEVIDHLGTIAKSGTKEFLSALGQDQAKDSQLIGQFGVGFYSAFIVADKVTVKTRAAGVSADKAVLWESAGEG
EYSVADIDKKERGTEITLHLREDEKAFLNDWRLREIIGKYSDHIGLPVEILAKEYDDEGKETGIKWEKINKAQALWTRAK
NEISEEEYQEFYKHLSHDFTDPLLWAHNKVEGNQEYTSLLYVPAKAPWDLFNREHKHGLKLYVQRVFIMDDAQVFMPNYL
RFMRGLLDSNDLPLNVSREILQDNKVTSALRKALTKRALQMLEKLAKDDAEKYQRFWQEFGLVLKEGPAEDFANKETIAK
LLRFASTHNDSSQQSVSLEDYVARMKEGQKAIYYITADTYVAAKNSPHLELFNKKGIEVLLLSDRIDEWMLSYLTEFDGK
PLQTISKADLDLGDLADKEEDSQKAQDEQYASFVERVKTLLGERVKEVRLTHRLTDTPAVVSTGDDQMTTQMAKLFAAAG
QAMPEVKYTFELNPEHGLVQKVAEIADEQQFADWIELLLEQAMLAERGSLENPVAFIKRMNTLLSKLTSH

Specific function: Molecular chaperone. Has ATPase activity

COG id: COG0326

COG function: function code O; Molecular chaperone, HSP90 family

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 90 family

Homologues:

Organism=Homo sapiens, GI20149594, Length=683, Percent_Identity=36.896046852123, Blast_Score=425, Evalue=1e-119,
Organism=Homo sapiens, GI4507677, Length=679, Percent_Identity=36.2297496318115, Blast_Score=405, Evalue=1e-113,
Organism=Homo sapiens, GI155722983, Length=636, Percent_Identity=35.8490566037736, Blast_Score=380, Evalue=1e-105,
Organism=Homo sapiens, GI154146191, Length=414, Percent_Identity=36.7149758454106, Blast_Score=271, Evalue=1e-72,
Organism=Homo sapiens, GI153792590, Length=414, Percent_Identity=37.1980676328502, Blast_Score=269, Evalue=6e-72,
Organism=Escherichia coli, GI1786679, Length=621, Percent_Identity=76.4895330112721, Blast_Score=998, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17559162, Length=674, Percent_Identity=37.3887240356083, Blast_Score=450, Evalue=1e-126,
Organism=Caenorhabditis elegans, GI17542208, Length=676, Percent_Identity=35.9467455621302, Blast_Score=394, Evalue=1e-110,
Organism=Caenorhabditis elegans, GI115535205, Length=655, Percent_Identity=33.4351145038168, Blast_Score=330, Evalue=1e-90,
Organism=Caenorhabditis elegans, GI115535167, Length=437, Percent_Identity=36.6132723112128, Blast_Score=271, Evalue=6e-73,
Organism=Saccharomyces cerevisiae, GI6323840, Length=681, Percent_Identity=38.7665198237885, Blast_Score=455, Evalue=1e-129,
Organism=Saccharomyces cerevisiae, GI6325016, Length=685, Percent_Identity=38.2481751824818, Blast_Score=453, Evalue=1e-128,
Organism=Drosophila melanogaster, GI17647529, Length=690, Percent_Identity=36.8115942028986, Blast_Score=449, Evalue=1e-126,
Organism=Drosophila melanogaster, GI21357739, Length=633, Percent_Identity=38.7045813586098, Blast_Score=394, Evalue=1e-110,
Organism=Drosophila melanogaster, GI24586016, Length=650, Percent_Identity=33.6923076923077, Blast_Score=350, Evalue=2e-96,

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 2419 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): HTPG_PASMU (Q9CM20)

Other databases:

- EMBL:   AE004439
- RefSeq:   NP_245961.1
- ProteinModelPortal:   Q9CM20
- SMR:   Q9CM20
- GeneID:   1244371
- GenomeReviews:   AE004439_GR
- KEGG:   pmu:PM1024
- NMPDR:   fig|272843.1.peg.1024
- HOGENOM:   HBG631012
- OMA:   AIYYITA
- ProtClustDB:   PRK05218
- BioCyc:   PMUL272843:PM1024-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00505
- InterPro:   IPR003594
- InterPro:   IPR019805
- InterPro:   IPR001404
- InterPro:   IPR020575
- InterPro:   IPR020568
- Gene3D:   G3DSA:3.30.565.10
- PANTHER:   PTHR11528
- PIRSF:   PIRSF002583
- PRINTS:   PR00775
- SMART:   SM00387

Pfam domain/function: PF02518 HATPase_c; PF00183 HSP90; SSF55874 ATP_bd_ATPase; SSF54211 Ribosomal_S5_D2-typ_fold

EC number: NA

Molecular weight: Translated: 71853; Mature: 71722

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: PS00298 HSP90

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTNQETRGFQSEVKQLLQLMIHSLYSNKEIFLRELISNASDAADKLRFKALSVPELYEG
CCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHCC
DGDLKVRIRFDEEKGTLTISDNGIGMTRDEVIDHLGTIAKSGTKEFLSALGQDQAKDSQL
CCCEEEEEEEECCCCEEEECCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHH
IGQFGVGFYSAFIVADKVTVKTRAAGVSADKAVLWESAGEGEYSVADIDKKERGTEITLH
HHHHHHHHHHHHHHHCCEEEEHHHCCCCCCHHHHCCCCCCCCEEEECCCCCCCCCEEEEE
LREDEKAFLNDWRLREIIGKYSDHIGLPVEILAKEYDDEGKETGIKWEKINKAQALWTRA
EECCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCHHCCCCHHHHHHHHHHHHHH
KNEISEEEYQEFYKHLSHDFTDPLLWAHNKVEGNQEYTSLLYVPAKAPWDLFNREHKHGL
HHCCCHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCCEEEEEEECCCCCHHHHCCHHHHHH
KLYVQRVFIMDDAQVFMPNYLRFMRGLLDSNDLPLNVSREILQDNKVTSALRKALTKRAL
HHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHH
QMLEKLAKDDAEKYQRFWQEFGLVLKEGPAEDFANKETIAKLLRFASTHNDSSQQSVSLE
HHHHHHHHHHHHHHHHHHHHHCHHHCCCCCHHHCCHHHHHHHHHHHHCCCCCCHHCCCHH
DYVARMKEGQKAIYYITADTYVAAKNSPHLELFNKKGIEVLLLSDRIDEWMLSYLTEFDG
HHHHHHHCCCEEEEEEEECEEEEECCCCCEEEECCCCCEEEEECHHHHHHHHHHHHHCCC
KPLQTISKADLDLGDLADKEEDSQKAQDEQYASFVERVKTLLGERVKEVRLTHRLTDTPA
CHHHHHHHCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
VVSTGDDQMTTQMAKLFAAAGQAMPEVKYTFELNPEHGLVQKVAEIADEQQFADWIELLL
EEECCCHHHHHHHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
EQAMLAERGSLENPVAFIKRMNTLLSKLTSH
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
STNQETRGFQSEVKQLLQLMIHSLYSNKEIFLRELISNASDAADKLRFKALSVPELYEG
CCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHCC
DGDLKVRIRFDEEKGTLTISDNGIGMTRDEVIDHLGTIAKSGTKEFLSALGQDQAKDSQL
CCCEEEEEEEECCCCEEEECCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHH
IGQFGVGFYSAFIVADKVTVKTRAAGVSADKAVLWESAGEGEYSVADIDKKERGTEITLH
HHHHHHHHHHHHHHHCCEEEEHHHCCCCCCHHHHCCCCCCCCEEEECCCCCCCCCEEEEE
LREDEKAFLNDWRLREIIGKYSDHIGLPVEILAKEYDDEGKETGIKWEKINKAQALWTRA
EECCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCHHCCCCHHHHHHHHHHHHHH
KNEISEEEYQEFYKHLSHDFTDPLLWAHNKVEGNQEYTSLLYVPAKAPWDLFNREHKHGL
HHCCCHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCCEEEEEEECCCCCHHHHCCHHHHHH
KLYVQRVFIMDDAQVFMPNYLRFMRGLLDSNDLPLNVSREILQDNKVTSALRKALTKRAL
HHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHH
QMLEKLAKDDAEKYQRFWQEFGLVLKEGPAEDFANKETIAKLLRFASTHNDSSQQSVSLE
HHHHHHHHHHHHHHHHHHHHHCHHHCCCCCHHHCCHHHHHHHHHHHHCCCCCCHHCCCHH
DYVARMKEGQKAIYYITADTYVAAKNSPHLELFNKKGIEVLLLSDRIDEWMLSYLTEFDG
HHHHHHHCCCEEEEEEEECEEEEECCCCCEEEECCCCCEEEEECHHHHHHHHHHHHHCCC
KPLQTISKADLDLGDLADKEEDSQKAQDEQYASFVERVKTLLGERVKEVRLTHRLTDTPA
CHHHHHHHCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
VVSTGDDQMTTQMAKLFAAAGQAMPEVKYTFELNPEHGLVQKVAEIADEQQFADWIELLL
EEECCCHHHHHHHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
EQAMLAERGSLENPVAFIKRMNTLLSKLTSH
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11248100