Click here to switch to the map view.

The map label for this gene is wbjD [H]

Identifier: 15602874

GI number: 15602874

Start: 1190387

End: 1191517

Strand: Direct

Name: wbjD [H]

Synonym: PM1009

Alternate gene names: 15602874

Gene position: 1190387-1191517 (Clockwise)

Preceding gene: 15602873

Following gene: 15602875

Centisome position: 52.73

GC content: 40.23

Gene sequence:

>1131_bases
ATGAAAAAGCTAAAAGTCATGACGGTTGTTGGTACTCGACCAGAAATTATTCGCTTATCTCGAGTCATTGTGGCTTGTGA
TAAACACTTTCAGCACATTCTTGTCCATACTGGACAAAACTATGACTACGAATTGAACGAGGTCTTTTTCCATGATTTAG
GTATTCGCAAACCTGACTACTTCCTTAATGCTGCGGGAAAAACCAGTTCAGCCACCATCGGAAATGTCATTATTGCCGTT
GATCAATTACTGGAGGAAACCCAGCCAGAAGCATTATTAGTTCTTGGTGATACCAATAGCTGCCTTGCCGTATTACCCGC
CAAGCGTCGAAAAATCCCAACGTTCCATATGGAAGCAGGAAATCGTTGTTTTGATATGCGTGTGCCAGAAGAAATCAATC
GTCGTATTGTAGATCATACAGCCGACATTAACCTGACTTACAGCACTATCGCAAGAGATTACCTCCTCGCTGAAGGACTA
AGTCCAGATCTCATCATCAAGACAGGGAGTCCGATGTTTGAAGTACTGCATTTCTATCATGAGCAGATTAAGCACTCAAA
AATATTAGATAAATTAGGATTAACCCCTTTCCAATATTTTGTAGTCAGTGCGCACCGCGAAGAAAATATTAATTCAGAAC
CGCACTTTTTGGATTTAATCCATACATTAAATGCGGTTGCGAAAAAATATCAATATCCTGTGATCGTTTCGACACATCCA
AGAACCCGAAAACGGATCGAGGAGTTAAACATCACTTTTCATCCATTAATTCAGCTATTAAAACCGTTAGGCTTCCTTGA
CTACAACAAATTACAGCTCATGGCAAAAGCCACTCTATCTGATAGTGGAACGATCAATGAAGAGTCCTCTATTTTAAATT
TTCCTGCATTAAATCTACGACAGGCTCATGAAAGACCTGAAGGAATGGAGGAAGCGGCTGTCATGTTAGTTGGACTACAA
GCTGAACGTGTTTTACAAGGTTTAGCTATTCTTGATGAGCAACGTCGTGGACAAGAGCGAGATTTACGCTTAGTCGCAGA
TTACAGTATGCCGAATGTAAGTGCCAAAGTGATACGTATCCTTTTAAGTTATACCGATTATGTTAACCGCGTTATTTGGA
AAAAATACTGA

Upstream 100 bases:

>100_bases
TCATGATGAGATGTTTGTCATGTTATGGGCAAATGAAATATTTGACCGTGAAAAACCCGATACGTATGCCATGCCAATTA
CATCTTAATAGGAATAACTA

Downstream 100 bases:

>100_bases
TGAAGATTTTACTATTAACTCAATGGTTTGAGCCCGAGCCAGCTATTAAAGGGTTGGCATTTGCAAAAGAATTAAAAGCG
CAGGGACATGACGTACAAGT

Product: UDP-N-acetylglucosamine 2-epimerase

Products: NA

Alternate protein names: UDP-GlcNAc-2-epimerase [H]

Number of amino acids: Translated: 376; Mature: 376

Protein sequence:

>376_residues
MKKLKVMTVVGTRPEIIRLSRVIVACDKHFQHILVHTGQNYDYELNEVFFHDLGIRKPDYFLNAAGKTSSATIGNVIIAV
DQLLEETQPEALLVLGDTNSCLAVLPAKRRKIPTFHMEAGNRCFDMRVPEEINRRIVDHTADINLTYSTIARDYLLAEGL
SPDLIIKTGSPMFEVLHFYHEQIKHSKILDKLGLTPFQYFVVSAHREENINSEPHFLDLIHTLNAVAKKYQYPVIVSTHP
RTRKRIEELNITFHPLIQLLKPLGFLDYNKLQLMAKATLSDSGTINEESSILNFPALNLRQAHERPEGMEEAAVMLVGLQ
AERVLQGLAILDEQRRGQERDLRLVADYSMPNVSAKVIRILLSYTDYVNRVIWKKY

Sequences:

>Translated_376_residues
MKKLKVMTVVGTRPEIIRLSRVIVACDKHFQHILVHTGQNYDYELNEVFFHDLGIRKPDYFLNAAGKTSSATIGNVIIAV
DQLLEETQPEALLVLGDTNSCLAVLPAKRRKIPTFHMEAGNRCFDMRVPEEINRRIVDHTADINLTYSTIARDYLLAEGL
SPDLIIKTGSPMFEVLHFYHEQIKHSKILDKLGLTPFQYFVVSAHREENINSEPHFLDLIHTLNAVAKKYQYPVIVSTHP
RTRKRIEELNITFHPLIQLLKPLGFLDYNKLQLMAKATLSDSGTINEESSILNFPALNLRQAHERPEGMEEAAVMLVGLQ
AERVLQGLAILDEQRRGQERDLRLVADYSMPNVSAKVIRILLSYTDYVNRVIWKKY
>Mature_376_residues
MKKLKVMTVVGTRPEIIRLSRVIVACDKHFQHILVHTGQNYDYELNEVFFHDLGIRKPDYFLNAAGKTSSATIGNVIIAV
DQLLEETQPEALLVLGDTNSCLAVLPAKRRKIPTFHMEAGNRCFDMRVPEEINRRIVDHTADINLTYSTIARDYLLAEGL
SPDLIIKTGSPMFEVLHFYHEQIKHSKILDKLGLTPFQYFVVSAHREENINSEPHFLDLIHTLNAVAKKYQYPVIVSTHP
RTRKRIEELNITFHPLIQLLKPLGFLDYNKLQLMAKATLSDSGTINEESSILNFPALNLRQAHERPEGMEEAAVMLVGLQ
AERVLQGLAILDEQRRGQERDLRLVADYSMPNVSAKVIRILLSYTDYVNRVIWKKY

Specific function: Catalyzes the reversible epimerization at C-2 of UDP-N- acetylglucosamine (UDP-GlcNAc) to produce UDP-N-acetylmannosamine (UDP-ManNAc), the activated donor of ManNAc residues [H]

COG id: COG0381

COG function: function code M; UDP-N-acetylglucosamine 2-epimerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-N-acetylglucosamine 2-epimerase family [H]

Homologues:

Organism=Escherichia coli, GI48994967, Length=342, Percent_Identity=30.4093567251462, Blast_Score=110, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003331 [H]

Pfam domain/function: PF02350 Epimerase_2 [H]

EC number: =5.1.3.14 [H]

Molecular weight: Translated: 43022; Mature: 43022

Theoretical pI: Translated: 7.80; Mature: 7.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLKVMTVVGTRPEIIRLSRVIVACDKHFQHILVHTGQNYDYELNEVFFHDLGIRKPDY
CCCEEEEEEECCCCHHHHHHHHHHHHHHHHHEEEEECCCCCCEEHHHHHHHHCCCCCCCC
FLNAAGKTSSATIGNVIIAVDQLLEETQPEALLVLGDTNSCLAVLPAKRRKIPTFHMEAG
EEECCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEEEECHHHCCCCEEEECCC
NRCFDMRVPEEINRRIVDHTADINLTYSTIARDYLLAEGLSPDLIIKTGSPMFEVLHFYH
CEEEECCCCHHHHHHHHCCCCCCEEEHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHH
EQIKHSKILDKLGLTPFQYFVVSAHREENINSEPHFLDLIHTLNAVAKKYQYPVIVSTHP
HHHHHHHHHHHHCCCHHHHHEEEHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCEEEECCC
RTRKRIEELNITFHPLIQLLKPLGFLDYNKLQLMAKATLSDSGTINEESSILNFPALNLR
HHHHHHHHCCCCHHHHHHHHHHCCCCCCHHHHHEEHHHCCCCCCCCCCCCEECCCCCCHH
QAHERPEGMEEAAVMLVGLQAERVLQGLAILDEQRRGQERDLRLVADYSMPNVSAKVIRI
HHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHH
LLSYTDYVNRVIWKKY
HHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKKLKVMTVVGTRPEIIRLSRVIVACDKHFQHILVHTGQNYDYELNEVFFHDLGIRKPDY
CCCEEEEEEECCCCHHHHHHHHHHHHHHHHHEEEEECCCCCCEEHHHHHHHHCCCCCCCC
FLNAAGKTSSATIGNVIIAVDQLLEETQPEALLVLGDTNSCLAVLPAKRRKIPTFHMEAG
EEECCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEEEECHHHCCCCEEEECCC
NRCFDMRVPEEINRRIVDHTADINLTYSTIARDYLLAEGLSPDLIIKTGSPMFEVLHFYH
CEEEECCCCHHHHHHHHCCCCCCEEEHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHH
EQIKHSKILDKLGLTPFQYFVVSAHREENINSEPHFLDLIHTLNAVAKKYQYPVIVSTHP
HHHHHHHHHHHHCCCHHHHHEEEHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCEEEECCC
RTRKRIEELNITFHPLIQLLKPLGFLDYNKLQLMAKATLSDSGTINEESSILNFPALNLR
HHHHHHHHCCCCHHHHHHHHHHCCCCCCHHHHHEEHHHCCCCCCCCCCCCEECCCCCCHH
QAHERPEGMEEAAVMLVGLQAERVLQGLAILDEQRRGQERDLRLVADYSMPNVSAKVIRI
HHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHH
LLSYTDYVNRVIWKKY
HHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]