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The map label for this gene is ruvA

Identifier: 15602842

GI number: 15602842

Start: 1148739

End: 1149353

Strand: Reverse

Name: ruvA

Synonym: PM0977

Alternate gene names: 15602842

Gene position: 1149353-1148739 (Counterclockwise)

Preceding gene: 15602843

Following gene: 15602841

Centisome position: 50.91

GC content: 40.16

Gene sequence:

>615_bases
ATGATTGGTCATTTGACGGGACGTTTAGTTGAAAAACACCCTCCTGAGATTTTGTTAGATGTGCAAGGCGTTGGCTACGA
ATTATTATTACCGATGACCAGCTTTTATCAGCTTCCCGATATTGGTCAACAGACAGCTCTATTTACTCATCTTGTTGTGC
GTGAAGATGCACATTTACTGTTTGGTTTTTCGCAAAAAACCGACCGCACTTTGTTTCGTGAATTAATCAAAACCAATGGT
GTAGGACCTAAGCTCGCACTGGCTATTTTATCAGCCATGTCAGTGGAAGAGTTTGCTTATGCGATTGAACGTGAAGAACT
CTCTAAATTAGTGAAGATTCCTGGGGTTGGTAAGAAAACAGCAGAACGTTTATTAGTGGAATTAAAAGGGAAGTTCAAAG
GCATTCAACAAGAAGACTTCTTTATTGAAAGTCAACATCTTAAACAGCCTGAACATGCTTTAAATGAACAAGATATCCCT
GCCAGTGAAGCTATTTCTGCGCTGATTGCGTTAGGTTATAAAGCCGCAGAAGCTGAAAAACTGGTGAAAAAAATCAGCAA
GCCGGCACTTTCTAGTGAGCAACTTATCCGTGAAGCATTAAAAGCCGCCTTATAA

Upstream 100 bases:

>100_bases
GCGATACAGTCGAGGACGCTTTCGTTTAAAAATTTAACTGGATGTTCATCCAGTTTTATTTTATGCTATACAACAAAATA
AATGATGTGATGAGGAAGAT

Downstream 100 bases:

>100_bases
TCTTTAAGTGAAAAGAACATGATTGAAGCAGATAGAATTATTAGTACAAGTGCGAAAGGCGATGAAGAGTATATTGATCG
TGCGATTCGTCCAAAATTGC

Product: Holliday junction DNA helicase RuvA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 204; Mature: 204

Protein sequence:

>204_residues
MIGHLTGRLVEKHPPEILLDVQGVGYELLLPMTSFYQLPDIGQQTALFTHLVVREDAHLLFGFSQKTDRTLFRELIKTNG
VGPKLALAILSAMSVEEFAYAIEREELSKLVKIPGVGKKTAERLLVELKGKFKGIQQEDFFIESQHLKQPEHALNEQDIP
ASEAISALIALGYKAAEAEKLVKKISKPALSSEQLIREALKAAL

Sequences:

>Translated_204_residues
MIGHLTGRLVEKHPPEILLDVQGVGYELLLPMTSFYQLPDIGQQTALFTHLVVREDAHLLFGFSQKTDRTLFRELIKTNG
VGPKLALAILSAMSVEEFAYAIEREELSKLVKIPGVGKKTAERLLVELKGKFKGIQQEDFFIESQHLKQPEHALNEQDIP
ASEAISALIALGYKAAEAEKLVKKISKPALSSEQLIREALKAAL
>Mature_204_residues
MIGHLTGRLVEKHPPEILLDVQGVGYELLLPMTSFYQLPDIGQQTALFTHLVVREDAHLLFGFSQKTDRTLFRELIKTNG
VGPKLALAILSAMSVEEFAYAIEREELSKLVKIPGVGKKTAERLLVELKGKFKGIQQEDFFIESQHLKQPEHALNEQDIP
ASEAISALIALGYKAAEAEKLVKKISKPALSSEQLIREALKAAL

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG0632

COG function: function code L; Holliday junction resolvasome, DNA-binding subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvA family

Homologues:

Organism=Escherichia coli, GI1788168, Length=204, Percent_Identity=58.8235294117647, Blast_Score=243, Evalue=6e-66,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVA_PASMU (P57893)

Other databases:

- EMBL:   AE004439
- RefSeq:   NP_245914.1
- ProteinModelPortal:   P57893
- SMR:   P57893
- GeneID:   1244324
- GenomeReviews:   AE004439_GR
- KEGG:   pmu:PM0977
- NMPDR:   fig|272843.1.peg.977
- HOGENOM:   HBG635309
- OMA:   LFGFAQK
- ProtClustDB:   PRK00116
- BioCyc:   PMUL272843:PM0977-MONOMER
- HAMAP:   MF_00031
- InterPro:   IPR011114
- InterPro:   IPR013849
- InterPro:   IPR003583
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR000085
- InterPro:   IPR010994
- Gene3D:   G3DSA:2.40.50.140
- SMART:   SM00278
- TIGRFAMs:   TIGR00084

Pfam domain/function: PF07499 RuvA_C; PF01330 RuvA_N; SSF50249 Nucleic_acid_OB; SSF47781 RuvA_2_like; SSF46929 RuvA_C-like

EC number: =3.6.4.12

Molecular weight: Translated: 22639; Mature: 22639

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGHLTGRLVEKHPPEILLDVQGVGYELLLPMTSFYQLPDIGQQTALFTHLVVREDAHLL
CCCCHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCHHE
FGFSQKTDRTLFRELIKTNGVGPKLALAILSAMSVEEFAYAIEREELSKLVKIPGVGKKT
ECCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
AERLLVELKGKFKGIQQEDFFIESQHLKQPEHALNEQDIPASEAISALIALGYKAAEAEK
HHHHHHHHHHHHCCCCCHHHEECHHHCCCCHHHCCCCCCCHHHHHHHHHHHCCHHHHHHH
LVKKISKPALSSEQLIREALKAAL
HHHHHHCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MIGHLTGRLVEKHPPEILLDVQGVGYELLLPMTSFYQLPDIGQQTALFTHLVVREDAHLL
CCCCHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCHHE
FGFSQKTDRTLFRELIKTNGVGPKLALAILSAMSVEEFAYAIEREELSKLVKIPGVGKKT
ECCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
AERLLVELKGKFKGIQQEDFFIESQHLKQPEHALNEQDIPASEAISALIALGYKAAEAEK
HHHHHHHHHHHHCCCCCHHHEECHHHCCCCHHHCCCCCCCHHHHHHHHHHHCCHHHHHHH
LVKKISKPALSSEQLIREALKAAL
HHHHHHCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11248100