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The map label for this gene is tolR [H]

Identifier: 15602834

GI number: 15602834

Start: 1142012

End: 1142434

Strand: Reverse

Name: tolR [H]

Synonym: PM0969

Alternate gene names: 15602834

Gene position: 1142434-1142012 (Counterclockwise)

Preceding gene: 15602835

Following gene: 15602833

Centisome position: 50.61

GC content: 39.72

Gene sequence:

>423_bases
ATGTCTTACCGCCGTAAACGTAGAGATGTGAAATCTGAGATCAACATCGTTCCTTTTTTGGACGTGTTACTCGTGTTGTT
GCTGATTTTTATGGCAACAGCGCCAATTATTAGCCAAAGTGTCCAAGTTGAATTGCCTGATGCGGTAGAGAGCCAAAGTG
TCAGTAATGAAGATAAAGTGCCGGTTATTTTAGAAGTAGCAGGCATCGGACAATATAGTTTAGCGATTGGTACAGAGCGC
TTAGAGGGACTGACTGAAGAGATGGTTACTCAATTGTCTAAACAAGAATTCGATAAAGATAATAATACGTTGTTTTTAGT
GGGTGGTGCGAGAGATGTTCCTTATGAAGAAGTGATCAAAGCACTCAACTTGCTTCATCTTGCAGGTATTAAATCTGTTG
GATTAATGACAAACCCGATTTAA

Upstream 100 bases:

>100_bases
ATTTGGTAAAAATGGCACACACTAATCGCTAAGCGATGTTTAGCGTTCCGTGCCTTTTGAGATAAGTGCGGTTGTTTTTT
TAGAATTTTGAGGGGAGATA

Downstream 100 bases:

>100_bases
TAAAAAGGCAATATTGTGCAAAGTAAGCAGAACAATAAAGACATCAGTGCGGTTATTCTTTCCGTCATTTTGCACGCGAT
CTTATTTGGCTTATTGATTT

Product: colicin uptake protein TolR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 140; Mature: 139

Protein sequence:

>140_residues
MSYRRKRRDVKSEINIVPFLDVLLVLLLIFMATAPIISQSVQVELPDAVESQSVSNEDKVPVILEVAGIGQYSLAIGTER
LEGLTEEMVTQLSKQEFDKDNNTLFLVGGARDVPYEEVIKALNLLHLAGIKSVGLMTNPI

Sequences:

>Translated_140_residues
MSYRRKRRDVKSEINIVPFLDVLLVLLLIFMATAPIISQSVQVELPDAVESQSVSNEDKVPVILEVAGIGQYSLAIGTER
LEGLTEEMVTQLSKQEFDKDNNTLFLVGGARDVPYEEVIKALNLLHLAGIKSVGLMTNPI
>Mature_139_residues
SYRRKRRDVKSEINIVPFLDVLLVLLLIFMATAPIISQSVQVELPDAVESQSVSNEDKVPVILEVAGIGQYSLAIGTERL
EGLTEEMVTQLSKQEFDKDNNTLFLVGGARDVPYEEVIKALNLLHLAGIKSVGLMTNPI

Specific function: Involved in the tonB-independent uptake of proteins [H]

COG id: COG0848

COG function: function code U; Biopolymer transport protein

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the exbD/tolR family [H]

Homologues:

Organism=Escherichia coli, GI1786959, Length=132, Percent_Identity=66.6666666666667, Blast_Score=154, Evalue=3e-39,
Organism=Escherichia coli, GI1789380, Length=123, Percent_Identity=35.7723577235772, Blast_Score=67, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003400 [H]

Pfam domain/function: PF02472 ExbD [H]

EC number: NA

Molecular weight: Translated: 15467; Mature: 15336

Theoretical pI: Translated: 4.49; Mature: 4.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYRRKRRDVKSEINIVPFLDVLLVLLLIFMATAPIISQSVQVELPDAVESQSVSNEDKV
CCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCHHHHCCCCCCCCC
PVILEVAGIGQYSLAIGTERLEGLTEEMVTQLSKQEFDKDNNTLFLVGGARDVPYEEVIK
CEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHH
ALNLLHLAGIKSVGLMTNPI
HHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
SYRRKRRDVKSEINIVPFLDVLLVLLLIFMATAPIISQSVQVELPDAVESQSVSNEDKV
CHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCHHHHCCCCCCCCC
PVILEVAGIGQYSLAIGTERLEGLTEEMVTQLSKQEFDKDNNTLFLVGGARDVPYEEVIK
CEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHH
ALNLLHLAGIKSVGLMTNPI
HHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800; 8921895 [H]