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The map label for this gene is dcuD [H]

Identifier: 15602798

GI number: 15602798

Start: 1101090

End: 1102478

Strand: Direct

Name: dcuD [H]

Synonym: PM0933

Alternate gene names: 15602798

Gene position: 1101090-1102478 (Clockwise)

Preceding gene: 15602797

Following gene: 15602800

Centisome position: 48.78

GC content: 42.84

Gene sequence:

>1389_bases
ATGCTAGGACTACTGCTTGGATTAGCGGTAACCATTCTTGTTGGTTATCTCATTGTCAAAAAGTACAAAGCACAATTTGT
GTTACTGTGTGGTGGTATTATCTTGATGTGTTTTGCGGTGCTATTTGGACTGGGTGAAATTCTGCCTGCCAATAAGTCAA
CTGGTTGGGTCGGTTTCGATATTTTTGAATTTATCAAAAACCTATTTAGTACACGTGCTGCCGATTTAGGTTTAATGATT
ATGGCTGTCGGCGGATTTGCTCGTTATATGGATAAAATCGGTGCCAGTGAAGCGTTAGTGAATATTGCAGTCAAGCCACT
CAACGCCATTAAAGCGCCTTATTTAGTCTTGGCCTTAGCCTATATTGTTGGACAAATCCTCAATATTTTTATTCCAAGTG
CATCAGGACTCGGTCTTCTTTTAATGCTCACTATTTTCCCGATCTTAGTCAATTTAGGCGTAAGTCGAGAAGGTGCAGCC
GCGCTTATCGCGACTACGGCCTGTTTGGATTTAGGACCCGCATCTGGTAATGCGGTATTAGCTGCCAAAACTGCCAATAT
TGACATTGCAGAATACTTTGTCGGTTATCAATTAAAATTAGCCATTATCACGATGTTAGTGATTTCAACCTCACATTTCT
TCGTGCAAAAATGGTTTGATAAAAGACAAGCTCTCACGGGTGGTGGTTCTGAATATGACGCAAGTCTAGAAGTTAACCTT
GACAAACAAGACAAGCAAGCCTCGCCGGTACCTGCTGTTTATGTCCTGCTCCCCCTCCTACCTTTAGTTCTCATCTTAAC
CTTTAGTAAATTATTGGTGAGTAGCATTAAAATGAATGTTGCCACCGCAATGATCATCAGCTTATTTATTGCTATGCTAT
TTGAGTTTGTGCGCAAAAAAGATGTCAAACAGGTGTTTGCCGAAATGCAAGTGTTCTTTGATGGCATGGGAAAACAATTT
GCAGCGGTAGTCACCCTCATTGTGGCGGGTGAAACCTTCGCTAAAGGGTTAACCGCTGTCGGCGCGATTGATACCATTAT
TTCAGGTGCACAAACCTTTGGCTTTGGTGTTTTCTTAATGACATTGGTGATGGTCTTAATTATTGCCCTTTCTGCTATTG
TTATGGGTTCGGGGAATGCACCTTTCTTCGCCTTTGCCGCTTTAGCCCCTAAAGTCGCTAGCGGATTAGGTATTTCACCT
GTCTTGATGGTTCTCCCAATGCAACTGGTAGCAGGTATTGCAAGAAGTATGTCGCCAATTACGGCTGTCATTGTCGCAGT
ATCCGGTGTGGCGAATGTGTCACCGTTTGATTTGATTAAGCGTACCGCGTTGCCAATGGCCTTTGCCTTGATTACGGTAT
TCTTGGGTACCTTCCTACTCTACCACTAA

Upstream 100 bases:

>100_bases
ACAGTCCTGATGAATACTTAAATATCGACTCCATCGAACCGAGAGTCAAACTCGTATCTGAAGTCATAAAATATTGTACT
CAACATAAAGGAGGCACGTC

Downstream 100 bases:

>100_bases
TTATCTCTTATCATTCGGGCGTACAATGTACGCCCATTATTTTTGTGACAGCACGCTACTTTATCTAAACATGGCTAATT
CTCTTATCGAATAAAAGCAA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 462; Mature: 462

Protein sequence:

>462_residues
MLGLLLGLAVTILVGYLIVKKYKAQFVLLCGGIILMCFAVLFGLGEILPANKSTGWVGFDIFEFIKNLFSTRAADLGLMI
MAVGGFARYMDKIGASEALVNIAVKPLNAIKAPYLVLALAYIVGQILNIFIPSASGLGLLLMLTIFPILVNLGVSREGAA
ALIATTACLDLGPASGNAVLAAKTANIDIAEYFVGYQLKLAIITMLVISTSHFFVQKWFDKRQALTGGGSEYDASLEVNL
DKQDKQASPVPAVYVLLPLLPLVLILTFSKLLVSSIKMNVATAMIISLFIAMLFEFVRKKDVKQVFAEMQVFFDGMGKQF
AAVVTLIVAGETFAKGLTAVGAIDTIISGAQTFGFGVFLMTLVMVLIIALSAIVMGSGNAPFFAFAALAPKVASGLGISP
VLMVLPMQLVAGIARSMSPITAVIVAVSGVANVSPFDLIKRTALPMAFALITVFLGTFLLYH

Sequences:

>Translated_462_residues
MLGLLLGLAVTILVGYLIVKKYKAQFVLLCGGIILMCFAVLFGLGEILPANKSTGWVGFDIFEFIKNLFSTRAADLGLMI
MAVGGFARYMDKIGASEALVNIAVKPLNAIKAPYLVLALAYIVGQILNIFIPSASGLGLLLMLTIFPILVNLGVSREGAA
ALIATTACLDLGPASGNAVLAAKTANIDIAEYFVGYQLKLAIITMLVISTSHFFVQKWFDKRQALTGGGSEYDASLEVNL
DKQDKQASPVPAVYVLLPLLPLVLILTFSKLLVSSIKMNVATAMIISLFIAMLFEFVRKKDVKQVFAEMQVFFDGMGKQF
AAVVTLIVAGETFAKGLTAVGAIDTIISGAQTFGFGVFLMTLVMVLIIALSAIVMGSGNAPFFAFAALAPKVASGLGISP
VLMVLPMQLVAGIARSMSPITAVIVAVSGVANVSPFDLIKRTALPMAFALITVFLGTFLLYH
>Mature_462_residues
MLGLLLGLAVTILVGYLIVKKYKAQFVLLCGGIILMCFAVLFGLGEILPANKSTGWVGFDIFEFIKNLFSTRAADLGLMI
MAVGGFARYMDKIGASEALVNIAVKPLNAIKAPYLVLALAYIVGQILNIFIPSASGLGLLLMLTIFPILVNLGVSREGAA
ALIATTACLDLGPASGNAVLAAKTANIDIAEYFVGYQLKLAIITMLVISTSHFFVQKWFDKRQALTGGGSEYDASLEVNL
DKQDKQASPVPAVYVLLPLLPLVLILTFSKLLVSSIKMNVATAMIISLFIAMLFEFVRKKDVKQVFAEMQVFFDGMGKQF
AAVVTLIVAGETFAKGLTAVGAIDTIISGAQTFGFGVFLMTLVMVLIIALSAIVMGSGNAPFFAFAALAPKVASGLGISP
VLMVLPMQLVAGIARSMSPITAVIVAVSGVANVSPFDLIKRTALPMAFALITVFLGTFLLYH

Specific function: May have a role in the transport of dicarboxylates from the periplasm across the inner membrane. Seems not to be essential for growth. It is likely to be a cryptic gene, as no or low expression has been found under a number of growth conditions and when t

COG id: COG3069

COG function: function code C; C4-dicarboxylate transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dcuC/dcuD transporter (TC 2.A.61) family [H]

Homologues:

Organism=Escherichia coli, GI1789622, Length=469, Percent_Identity=44.7761194029851, Blast_Score=407, Evalue=1e-115,
Organism=Escherichia coli, GI1786839, Length=429, Percent_Identity=37.7622377622378, Blast_Score=261, Evalue=5e-71,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018385
- InterPro:   IPR004669 [H]

Pfam domain/function: PF03606 DcuC [H]

EC number: NA

Molecular weight: Translated: 48944; Mature: 48944

Theoretical pI: Translated: 9.54; Mature: 9.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLGLLLGLAVTILVGYLIVKKYKAQFVLLCGGIILMCFAVLFGLGEILPANKSTGWVGFD
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCHHH
IFEFIKNLFSTRAADLGLMIMAVGGFARYMDKIGASEALVNIAVKPLNAIKAPYLVLALA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHH
YIVGQILNIFIPSASGLGLLLMLTIFPILVNLGVSREGAAALIATTACLDLGPASGNAVL
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCEEE
AAKTANIDIAEYFVGYQLKLAIITMLVISTSHFFVQKWFDKRQALTGGGSEYDASLEVNL
EEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEC
DKQDKQASPVPAVYVLLPLLPLVLILTFSKLLVSSIKMNVATAMIISLFIAMLFEFVRKK
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DVKQVFAEMQVFFDGMGKQFAAVVTLIVAGETFAKGLTAVGAIDTIISGAQTFGFGVFLM
HHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLVMVLIIALSAIVMGSGNAPFFAFAALAPKVASGLGISPVLMVLPMQLVAGIARSMSPI
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCHH
TAVIVAVSGVANVSPFDLIKRTALPMAFALITVFLGTFLLYH
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLGLLLGLAVTILVGYLIVKKYKAQFVLLCGGIILMCFAVLFGLGEILPANKSTGWVGFD
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCHHH
IFEFIKNLFSTRAADLGLMIMAVGGFARYMDKIGASEALVNIAVKPLNAIKAPYLVLALA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHH
YIVGQILNIFIPSASGLGLLLMLTIFPILVNLGVSREGAAALIATTACLDLGPASGNAVL
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCEEE
AAKTANIDIAEYFVGYQLKLAIITMLVISTSHFFVQKWFDKRQALTGGGSEYDASLEVNL
EEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEC
DKQDKQASPVPAVYVLLPLLPLVLILTFSKLLVSSIKMNVATAMIISLFIAMLFEFVRKK
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DVKQVFAEMQVFFDGMGKQFAAVVTLIVAGETFAKGLTAVGAIDTIISGAQTFGFGVFLM
HHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLVMVLIIALSAIVMGSGNAPFFAFAALAPKVASGLGISPVLMVLPMQLVAGIARSMSPI
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCHH
TAVIVAVSGVANVSPFDLIKRTALPMAFALITVFLGTFLLYH
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]