Click here to switch to the map view.

The map label for this gene is fbp [H]

Identifier: 15602795

GI number: 15602795

Start: 1098047

End: 1099048

Strand: Direct

Name: fbp [H]

Synonym: PM0930

Alternate gene names: 15602795

Gene position: 1098047-1099048 (Clockwise)

Preceding gene: 15602790

Following gene: 15602796

Centisome position: 48.64

GC content: 41.22

Gene sequence:

>1002_bases
ATGAAAACGTTGGGGCAATTTATTGTTGAAAAACAAGCAGAATATCCAAATGCAAAAGGGGAACTCAGTGGGATTTTATC
CTCCATTCGATTGGTCGCAAAGGTGATCCATCGAGATATCAATAAAGCAGGGTTAACCAATAACATTATTGGTACATCAG
GGGCTGAAAATGTGCAGGGCGAAACCCAAATGAAATTGGATCTGTTCGCACATAACACCATGAAACAAGCCTTAATCAGC
CGTGAAGAAGTCGCTGGTTTTGCCTCCGAAGAAGAAGAAAATTTTGTTGCTTTCGATACAGAACGTGGACGCAATGCTAA
ATATGTGATTTTAACCGATCCCCTCGATGGCTCTTCCAACATTGATGTTAACGTTGCAGTCGGCACAATCTTCTCTATCT
ACCGCCGTGTTTCTCCTATCGGCACGCCTGTGACCTTAGCAGATTTTATGCAACCTGGTAATCGACAAGTCGCCGCTGGT
TACATCGTTTATGGTTCTTCAACCATGTTAGTGTATACCACAGGTAATGGTGTTAACGGGTTCACTTATGATCCATCATT
AGGGGTATTCTGTTTATCCCATGAAAATATTCAAATTCCTGCGAATGGAAAAATTTACTCTATCAATGAAGGTCAATATT
TGAAATTCCCGCAAGGCGTGAAAAAATACATTAAATATTGCCAAGAAGAAGATAAAGCAACACATCGCCCTTATACTTCT
CGCTATATCGGCTCACTCGTATCCGATTTTCATCGTAACATGCTGAAAGGTGGGATCTATATTTACCCAAGCGCAACGAA
CTATCCGAACGGCAAACTTCGTTTATTATATGAAGGTAATCCAATGGCATTTTTAGCGGAACAAGCAGGCGGTATGGCGA
GTGATGGTTATCAGCGTATTTTAGATATTCAACCGACGGAATTACATCAACGCGTGCCACTTTTCCTCGGTTCGAAAGAG
ATGGTGGAAAAAGCACAAGACTTTATGAAAACATTTGGCTAA

Upstream 100 bases:

>100_bases
ATCACATTGTTAACATTCGACTTTTCTATGATAAACCTAAGGTTGCTATAATAAATCAACTCATCAAATGAGTAAATTTA
TTAATAACAAGGATTAATAT

Downstream 100 bases:

>100_bases
CACTGAATGTAAAGAAATTAAAAGAGCCCTCAATTCATTTGACGGGCTTTTTTCGATTGCCTATTATATCGCCAAATTAG
AATAGAGAGGATTTACTTTT

Product: fructose-1,6-bisphosphatase

Products: NA

Alternate protein names: FBPase class 1; D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 [H]

Number of amino acids: Translated: 333; Mature: 333

Protein sequence:

>333_residues
MKTLGQFIVEKQAEYPNAKGELSGILSSIRLVAKVIHRDINKAGLTNNIIGTSGAENVQGETQMKLDLFAHNTMKQALIS
REEVAGFASEEEENFVAFDTERGRNAKYVILTDPLDGSSNIDVNVAVGTIFSIYRRVSPIGTPVTLADFMQPGNRQVAAG
YIVYGSSTMLVYTTGNGVNGFTYDPSLGVFCLSHENIQIPANGKIYSINEGQYLKFPQGVKKYIKYCQEEDKATHRPYTS
RYIGSLVSDFHRNMLKGGIYIYPSATNYPNGKLRLLYEGNPMAFLAEQAGGMASDGYQRILDIQPTELHQRVPLFLGSKE
MVEKAQDFMKTFG

Sequences:

>Translated_333_residues
MKTLGQFIVEKQAEYPNAKGELSGILSSIRLVAKVIHRDINKAGLTNNIIGTSGAENVQGETQMKLDLFAHNTMKQALIS
REEVAGFASEEEENFVAFDTERGRNAKYVILTDPLDGSSNIDVNVAVGTIFSIYRRVSPIGTPVTLADFMQPGNRQVAAG
YIVYGSSTMLVYTTGNGVNGFTYDPSLGVFCLSHENIQIPANGKIYSINEGQYLKFPQGVKKYIKYCQEEDKATHRPYTS
RYIGSLVSDFHRNMLKGGIYIYPSATNYPNGKLRLLYEGNPMAFLAEQAGGMASDGYQRILDIQPTELHQRVPLFLGSKE
MVEKAQDFMKTFG
>Mature_333_residues
MKTLGQFIVEKQAEYPNAKGELSGILSSIRLVAKVIHRDINKAGLTNNIIGTSGAENVQGETQMKLDLFAHNTMKQALIS
REEVAGFASEEEENFVAFDTERGRNAKYVILTDPLDGSSNIDVNVAVGTIFSIYRRVSPIGTPVTLADFMQPGNRQVAAG
YIVYGSSTMLVYTTGNGVNGFTYDPSLGVFCLSHENIQIPANGKIYSINEGQYLKFPQGVKKYIKYCQEEDKATHRPYTS
RYIGSLVSDFHRNMLKGGIYIYPSATNYPNGKLRLLYEGNPMAFLAEQAGGMASDGYQRILDIQPTELHQRVPLFLGSKE
MVEKAQDFMKTFG

Specific function: INVOLVED IN SEVERAL METABOLIC PATHWAYS. IN E.COLI AND YEAST IT IS NECESSARY FOR GROWTH ON SUBSTANCES SUCH AS GLYCEROL, SUCCINATE AND ACETATE. [C]

COG id: COG0158

COG function: function code G; Fructose-1,6-bisphosphatase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FBPase class 1 family [H]

Homologues:

Organism=Homo sapiens, GI189083692, Length=332, Percent_Identity=42.1686746987952, Blast_Score=244, Evalue=7e-65,
Organism=Homo sapiens, GI16579888, Length=332, Percent_Identity=42.1686746987952, Blast_Score=244, Evalue=7e-65,
Organism=Homo sapiens, GI22907028, Length=325, Percent_Identity=41.8461538461538, Blast_Score=238, Evalue=4e-63,
Organism=Escherichia coli, GI1790679, Length=332, Percent_Identity=70.7831325301205, Blast_Score=491, Evalue=1e-140,
Organism=Caenorhabditis elegans, GI17508131, Length=330, Percent_Identity=45.1515151515152, Blast_Score=300, Evalue=7e-82,
Organism=Saccharomyces cerevisiae, GI6323409, Length=329, Percent_Identity=41.6413373860182, Blast_Score=262, Evalue=7e-71,
Organism=Drosophila melanogaster, GI45550998, Length=328, Percent_Identity=46.9512195121951, Blast_Score=282, Evalue=2e-76,
Organism=Drosophila melanogaster, GI19921562, Length=328, Percent_Identity=46.9512195121951, Blast_Score=281, Evalue=3e-76,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000146
- InterPro:   IPR020548 [H]

Pfam domain/function: PF00316 FBPase [H]

EC number: =3.1.3.11 [H]

Molecular weight: Translated: 36862; Mature: 36862

Theoretical pI: Translated: 7.14; Mature: 7.14

Prosite motif: PS00124 FBPASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTLGQFIVEKQAEYPNAKGELSGILSSIRLVAKVIHRDINKAGLTNNIIGTSGAENVQG
CCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
ETQMKLDLFAHNTMKQALISREEVAGFASEEEENFVAFDTERGRNAKYVILTDPLDGSSN
CCEEEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCEEEEEEECCCCCCCC
IDVNVAVGTIFSIYRRVSPIGTPVTLADFMQPGNRQVAAGYIVYGSSTMLVYTTGNGVNG
EEEEEHHHHHHHHHHHHCCCCCCEEHHHHHCCCCCEEEEEEEEECCCEEEEEEECCCCCC
FTYDPSLGVFCLSHENIQIPANGKIYSINEGQYLKFPQGVKKYIKYCQEEDKATHRPYTS
EEECCCCCEEEEECCCEEECCCCEEEEECCCCEEECCHHHHHHHHHHHHHHHHCCCCHHH
RYIGSLVSDFHRNMLKGGIYIYPSATNYPNGKLRLLYEGNPMAFLAEQAGGMASDGYQRI
HHHHHHHHHHHHHHHHCCEEEEECCCCCCCCEEEEEECCCCEEEEEHHCCCCCCCCHHHE
LDIQPTELHQRVPLFLGSKEMVEKAQDFMKTFG
ECCCHHHHHHCCCEEECCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKTLGQFIVEKQAEYPNAKGELSGILSSIRLVAKVIHRDINKAGLTNNIIGTSGAENVQG
CCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
ETQMKLDLFAHNTMKQALISREEVAGFASEEEENFVAFDTERGRNAKYVILTDPLDGSSN
CCEEEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCEEEEEEECCCCCCCC
IDVNVAVGTIFSIYRRVSPIGTPVTLADFMQPGNRQVAAGYIVYGSSTMLVYTTGNGVNG
EEEEEHHHHHHHHHHHHCCCCCCEEHHHHHCCCCCEEEEEEEEECCCEEEEEEECCCCCC
FTYDPSLGVFCLSHENIQIPANGKIYSINEGQYLKFPQGVKKYIKYCQEEDKATHRPYTS
EEECCCCCEEEEECCCEEECCCCEEEEECCCCEEECCHHHHHHHHHHHHHHHHCCCCHHH
RYIGSLVSDFHRNMLKGGIYIYPSATNYPNGKLRLLYEGNPMAFLAEQAGGMASDGYQRI
HHHHHHHHHHHHHHHHCCEEEEECCCCCCCCEEEEEECCCCEEEEEHHCCCCCCCCHHHE
LDIQPTELHQRVPLFLGSKEMVEKAQDFMKTFG
ECCCHHHHHHCCCEEECCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA