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The map label for this gene is hfq

Identifier: 15602771

GI number: 15602771

Start: 1064798

End: 1065088

Strand: Direct

Name: hfq

Synonym: PM0906

Alternate gene names: 15602771

Gene position: 1064798-1065088 (Clockwise)

Preceding gene: 15602770

Following gene: 15602772

Centisome position: 47.17

GC content: 34.36

Gene sequence:

>291_bases
ATGGCAAAAGGACAATCTTTACAAGATCCTTATTTAAACGCATTACGTCGTGAACGTATCCCTGTTTCCATTTACCTCGT
AAATGGGATTAAACTACAAGGTCAGATTGAATCATTTGATCAATTTGTTATTTTATTAAAAAATACAGTTAATCAAATGG
TGTACAAACACGCAATTTCAACTGTTGTTCCTGCGCGCTCAGTGTCTCATCACAATAATAGCAATAATTCCAATCAACAG
AATTATCAACAAGAGCAACAAACTGACAGCAACGTAGAAAAAGCAGAATAG

Upstream 100 bases:

>100_bases
AATTAATTTATTGTTATATTGAGATTTGGAGGAAATACAGAACTCTCTGTGTTTAGCTAGTTGTATCATTTTATTTAGAT
TTAAAAGAAGGAAAGAAAAA

Downstream 100 bases:

>100_bases
TTTCAAGTTGAACACATTTATTGCAAGTGCGGTAGATCTTCAGAATGAATCGACCGCACTTTCTTCATTACCTTCACCAC
ATTCTGAATCCCTTTTTGAT

Product: RNA-binding protein Hfq

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 96; Mature: 95

Protein sequence:

>96_residues
MAKGQSLQDPYLNALRRERIPVSIYLVNGIKLQGQIESFDQFVILLKNTVNQMVYKHAISTVVPARSVSHHNNSNNSNQQ
NYQQEQQTDSNVEKAE

Sequences:

>Translated_96_residues
MAKGQSLQDPYLNALRRERIPVSIYLVNGIKLQGQIESFDQFVILLKNTVNQMVYKHAISTVVPARSVSHHNNSNNSNQQ
NYQQEQQTDSNVEKAE
>Mature_95_residues
AKGQSLQDPYLNALRRERIPVSIYLVNGIKLQGQIESFDQFVILLKNTVNQMVYKHAISTVVPARSVSHHNNSNNSNQQN
YQQEQQTDSNVEKAE

Specific function: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs

COG id: COG1923

COG function: function code R; Uncharacterized host factor I protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hfq family

Homologues:

Organism=Escherichia coli, GI1790614, Length=83, Percent_Identity=84.3373493975904, Blast_Score=147, Evalue=1e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HFQ_PASMU (Q9CMC6)

Other databases:

- EMBL:   AE004439
- RefSeq:   NP_245843.1
- ProteinModelPortal:   Q9CMC6
- SMR:   Q9CMC6
- GeneID:   1244253
- GenomeReviews:   AE004439_GR
- KEGG:   pmu:PM0906
- NMPDR:   fig|272843.1.peg.906
- HOGENOM:   HBG645207
- OMA:   PYLNVLR
- ProtClustDB:   PRK00395
- BioCyc:   PMUL272843:PM0906-MONOMER
- HAMAP:   MF_00436
- InterPro:   IPR005001
- InterPro:   IPR010920
- InterPro:   IPR001163
- TIGRFAMs:   TIGR02383

Pfam domain/function: PF01423 LSM; SSF50182 Sm_like_riboprot

EC number: NA

Molecular weight: Translated: 10956; Mature: 10825

Theoretical pI: Translated: 8.94; Mature: 8.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKGQSLQDPYLNALRRERIPVSIYLVNGIKLQGQIESFDQFVILLKNTVNQMVYKHAIS
CCCCCCCCCHHHHHHHHCCCCEEEEEECCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHH
TVVPARSVSHHNNSNNSNQQNYQQEQQTDSNVEKAE
HHHCCHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
AKGQSLQDPYLNALRRERIPVSIYLVNGIKLQGQIESFDQFVILLKNTVNQMVYKHAIS
CCCCCCCCHHHHHHHHCCCCEEEEEECCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHH
TVVPARSVSHHNNSNNSNQQNYQQEQQTDSNVEKAE
HHHCCHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11248100